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51

Epitope spread is not critical for the relapse and progression of MOG 8-21 induced EAE in Biozzi ABH mice

Paul A. Smith, Margaret Morris-Downes, Nicole Heijmans, Gareth Pryce, Elizabeth Arter, Janet K. O'Neill, Bert 't Hart, David Baker, Sandra Amor

Journal:

Journal of Neuroimmunology

Year:

2005

Language:

english

File:

PDF, 207 KB

english, 2005

52

Restricted immune responses lead to CNS demyelination and axonal damage

Gianluigi Mancardi, Bert A ‘t Hart, Elisabetta Capello, Herbert P.M Brok, Avraham Ben-Nun, Luca Roccatagliata, Debora Giunti, Paola Gazzola, Mariella Dono, Nicole Kerlero de Rosbo, Monica Colombo, Ant

Journal:

Journal of Neuroimmunology

Year:

2000

Language:

english

File:

PDF, 1.08 MB

english, 2000

53

Rhesus monkeys are highly susceptible to experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein: characterisation of immunodominant T- and B-cell epitopes

Nicole Kerlero de Rosbo, Herbert P.M Brok, Jan Bauer, Joel F Kaye, Bert A ’t Hart, Avraham Ben-Nun

Journal:

Journal of Neuroimmunology

Year:

2000

Language:

english

File:

PDF, 1.56 MB

english, 2000

54

Novel monoclonal antibodies against proteolipid protein peptide 139–151 demonstrate demyelination and myelin uptake by macrophages in MS and marmoset EAE lesions

Jon D. Laman, Lizette Visser, Catharina B.M. Maassen, Corline J.A. de Groot, Laurina A. de Jong, Bert A. 't Hart, Marjan van Meurs, Marc M. Schellekens

Journal:

Journal of Neuroimmunology

Year:

2001

Language:

english

File:

PDF, 286 KB

english, 2001

55

Relation between limb toxicity and treatment outcomes after isolated limb perfusion for recurrent melanoma

Bart C Vrouenraets, Guus A.M Hart, Alexander M.M Eggermont, Joost M Klaase, Bert N van Geel, Omgo E Nieweg, Bin B.R Kroon

Journal:

Journal of the American College of Surgeons

Year:

1999

Language:

english

File:

PDF, 235 KB

english, 1999

56

Evaluating the validity of animal models for research into therapies for immune-based disorders

Bert A 't Hart, Sandra Amor, Margreet Jonker

Journal:

Drug Discovery Today

Year:

2004

Language:

english

File:

PDF, 257 KB

english, 2004

57

Broad spectrum immune monitoring in immune-mediated inflammatory disorders

Bert A. 't Hart, Kees Heije

Journal:

Drug Discovery Today

Year:

2005

Language:

english

File:

PDF, 615 KB

english, 2005

58

MRI-guided immunotherapy development for multiple sclerosis in a primate

Bert A. 't Hart, Paul Smith, Sandra Amor, Gustav J. Strijkers, Erwin L.A. Blezer

Journal:

Drug Discovery Today

Year:

2006

Language:

english

File:

PDF, 1.34 MB

english, 2006

59

Modelling of multiple sclerosis: lessons learned in a non-human primate

Bert A 't Hart, Jon D Laman, Jan Bauer, Erwin Blezer, Yvette van Kooyk, Rogier Q Hintzen

Journal:

The Lancet Neurology

Year:

2004

Language:

english

File:

PDF, 2.68 MB

english, 2004

60

Treatment with Anti-MHC-Class-II Antibody Postpones Kidney Allograft Rejection in Primates but Increases the Risk of CMV Activation

Margreet Jonker, Jan Ringers, Eva-Maria Kuhn, Bert't Hart, Roland Foulkes

Journal:

American Journal of Transplantation

Year:

2004

Language:

english

File:

PDF, 87 KB

english, 2004

61

Patient- and treatment-related factors associated with acute regional toxicity after isolated perfusion for melanoma of the extremities

Joost M. Klaase, Bin B.R. Kroon, Bert N. van Geel, Alexander M.M. Eggermont, Hilary R. Franklin, Guus A.M. Hart

Journal:

The American Journal of Surgery

Year:

1994

Language:

english

File:

PDF, 376 KB

english, 1994

62

Yin–Yang regulation of autoimmunity by DCs

Bert A. 't Hart, Yvette van Kooyk

Journal:

Trends in Immunology

Year:

2004

Language:

english

File:

PDF, 888 KB

english, 2004

63

IgG4 immunotherapy for the protection of surface receptors against complement mediated damage in autoimmunity

Mario Losen, Pilar Martínez-Martínez, Herbert Brok, Bert’t Hart, Paul Parren, Marc De Baets

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 51 KB

english, 2007

64

Non-invasive measurement of brain damage in a primate model of multiple sclerosis

Bert A. 't Hart, Jack Vogels, Jan Bauer, Herbert P.M. Brok, Erwin Blezer

Journal:

Trends in Molecular Medicine

Year:

2004

Language:

english

File:

PDF, 1.19 MB

english, 2004

65

Multiple sclerosis – a response-to-damage model

Bert A. ‘t Hart, Rogier Q. Hintzen, Jon D. Laman

Journal:

Trends in Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 547 KB

english, 2009

66

EAE: imperfect but useful models of multiple sclerosis

Bert A. ’t Hart, Bruno Gran, Robert Weissert

Journal:

Trends in Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 253 KB

english, 2011

67

Histopathological Characterization of Magnetic Resonance Imaging-Detectable Brain White Matter Lesions in a Primate Model of Multiple Sclerosis: A Correlative Study in the Experimental Autoimmune Encephalomyelitis Model in Common Marmosets (Callithrix jacchus)

Bert A. 't Hart, Jan Bauer, Henk-Jan Muller, Bert Melchers, Klaas Nicolay, Herbert Brok, Ronald E. Bontrop, Hans Lassmann, Luca Massacesi

Journal:

The American Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 2.33 MB

english, 1998

68

Liposome-mediated peptide loading of MHC-DR molecules in vivo

Bert A. 't Hart, Diënne G. Elferink, Jan Wouter Drijfhout, Gert Storm, Louis van Blooijs, Ronald E. Bontrop, René R.P. de Vries

Journal:

Year:

1997

Language:

english

File:

PDF, 618 KB

english, 1997

69

Expression of accessory molecules and cytokines in acute EAE in marmoset monkeys (Callithrix jacchus)

Jon D Laman, Marjan van Meurs, Marc M Schellekens, Mark de Boer, Bert Melchers, Luca Massacesi, Hans Lassmann, Eric Claassen, Bert A 't Hart

Journal:

Journal of Neuroimmunology

Year:

1998

Language:

english

File:

PDF, 1.25 MB

english, 1998

70

The major histocompatibility complex influences the ethiopathogenesis of MS-like disease in primates at multiple levels

Bert A ’t Hart, Herbert P.M Brok, Sandra Amor, Ronald E Bontrop

Journal:

Human Immunology

Year:

2001

Language:

english

File:

PDF, 109 KB

english, 2001

71

Towards a European nonhuman primate immune-tolerance network

Bert A ‘t Hart, Margreet Jonker

Journal:

Trends in Immunology

Year:

2002

Language:

english

File:

PDF, 209 KB

english, 2002

72

Phagocytes Containing a Disease-Promoting Toll-Like Receptor/Nod Ligand Are Present in the Brain during Demyelinating Disease in Primates

Lizette Visser, Marie-José Melief, Debby van Riel, Marjan van Meurs, Ella A. Sick, Seiichi Inamura, Jeffrey J. Bajramovic, Sandra Amor, Rogier Q. Hintzen, Leonie A. Boven, Bert A. ’t Hart, Jon D. Lama

Journal:

The American Journal of Pathology

Year:

2006

Language:

english

File:

PDF, 1.12 MB

english, 2006

73

Targeted delivery of CpG ODN to CD32 on human and monkey plasmacytoid dendritic cells augments IFNα secretion

Jurjen Tel, Niels Beenhakker, Gerrit Koopman, Bert’t Hart, Geert C. Mudde, I. Jolanda M. de Vries

Journal:

Year:

2012

Language:

english

File:

PDF, 935 KB

english, 2012

74

P300 Latency in Chronic Alcoholics and Depressed Patients : A Preliminary Report

RAY JOHNSON JR., ADOLF PFEFFERBAUM, TESSA HART, BERT S. KOPELL

Journal:

Annals of the New York Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 316 KB

english, 1984

75

Comparative analysis of inflammatory infiltrates in collagen-induced arthritis, kidney graft rejection and delayed-type hypersensitivity in non-human primates

Margreet Jonker, Jacqueline Wubben, Krista Haanstra, Michel Vierboom, Bert ‘t Hart

Journal:

Inflammation Research

Year:

2013

Language:

english

File:

PDF, 1.52 MB

english, 2013

76

Antibodies Against Human BLyS and APRIL Attenuate EAE Development in Marmoset Monkeys

S. Anwar Jagessar, Nicole Heijmans, Jan Bauer, Erwin L. A. Blezer, Jon D. Laman, Thi-Sau Migone, Matt N. Devalaraja, Bert A. ’t Hart

Journal:

Journal of Neuroimmune Pharmacology

Year:

2012

Language:

english

File:

PDF, 665 KB

english, 2012

77

An ear swelling reaction for in vivo monitoring of inflammatory T cell activity in collagen-arthritic rats

Bert A. 't Hart, Elizabeth Kraakman, Margreet Jonker

Journal:

Journal of Immunological Methods

Year:

1994

Language:

english

File:

PDF, 461 KB

english, 1994

78

Reactive oxygen species are involved in the pathogenesis of experimental allergic encephalomyelitis in Lewis rats

Sigrid R. Ruuls, Jan Bauer, Karin Sontrop, Ingeborg Huitinga, Bert A. 't Hart, Christine D. Dijkstra

Journal:

Journal of Neuroimmunology

Year:

1995

Language:

english

File:

PDF, 1.32 MB

english, 1995

79

Non-human primate models of multiple sclerosis

Bert A. ’t Hart, Jeffrey J. Bajramovic

Journal:

Drug Discovery Today: Disease Models

Year:

2008

Language:

english

File:

PDF, 3.33 MB

english, 2008

80

Preclinical evaluation of anti-rheumatic drugs in a non-human primate model of arthritic disease

Michel P.M. Vierboom, Elia Breedveld, Bert A. ’t Hart

Journal:

Drug Discovery Today: Disease Models

Year:

2008

Language:

english

File:

PDF, 1.21 MB

english, 2008

81

The marmoset monkey: a multi-purpose preclinical and translational model of human biology and disease

Bert A. ’t Hart, David H. Abbott, Katsuki Nakamura, Eberhard Fuchs

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 614 KB

english, 2012

82

Demyelination and axonal damage in a non-human primate model of multiple sclerosis

Gianluigi Mancardi, Bert’t Hart, Luca Roccatagliata, Herbert Brok, Debora Giunti, Ronald Bontrop, Luca Massacesi, Elisabetta Capello, Antonio Uccelli

Journal:

Journal of the Neurological Sciences

Year:

2001

Language:

english

File:

PDF, 1.29 MB

english, 2001

83

1H-NMR spectroscopy combined with pattern recognition analysis reveals characteristic chemical patterns in urines of MS patients and non-human primates with MS-like disease

Bert A 't Hart, Jack T.W.E Vogels, Gerwin Spijksma, Herbert P.M Brok, Chris Polman, Jan van der Greef

Journal:

Journal of the Neurological Sciences

Year:

2003

Language:

english

File:

PDF, 255 KB

english, 2003

84

Self- and Nonself-Recognition by C-Type Lectins on Dendritic Cells

Geijtenbeek, Teunis B.H., van Vliet, Sandra J., Engering, Anneke, 't Hart, Bert A., van Kooyk, Yvette

Journal:

Annual Review of Immunology

Year:

2004

Language:

english

File:

PDF, 322 KB

english, 2004

85

The Different Clinical Effects of Anti-BLyS, Anti-APRIL and Anti-CD20 Antibodies Point at a Critical Pathogenic Role of γ-Herpesvirus Infected B Cells in the Marmoset EAE Model

Anwar Jagessar, S., Fagrouch, Zahra, Heijmans, Nicole, Bauer, Jan, Laman, Jon D., Oh, Luke, Migone, Thi, Verschoor, Ernst J., ât Hart, Bert A.

Journal:

Journal of Neuroimmune Pharmacology

Year:

2013

Language:

english

File:

PDF, 636 KB

english, 2013

86

Chronic autoimmune-mediated inflammation: a senescent immune response to injury

’t Hart, Bert A., Chalan, Paulina, Koopman, Gerrit, Boots, Annemieke M.H.

Journal:

Drug Discovery Today

Year:

2013

Language:

english

File:

PDF, 483 KB

english, 2013

87

Commentary on Special Issue: CNS Diseases and the Immune System

Bert A. ‘t Hart, Wilfred F. den Dunnen

Journal:

Journal of Neuroimmune Pharmacology

Year:

2013

Language:

english

File:

PDF, 82 KB

english, 2013

88

Editorial

Bert A. ‘t Hart

Journal:

Journal of Neuroimmune Pharmacology

Year:

2013

Language:

english

File:

PDF, 101 KB

english, 2013

89

Oral Treatment with the NADPH Oxidase Antagonist Apocynin Mitigates Clinical and Pathological Features of Parkinsonism in the MPTP marmoset Model

Philippens, Ingrid H. C. H. M., Wubben, Jacqueline A., Finsen, Bente, Hart, Bert A.

Journal:

Journal of Neuroimmune Pharmacology

Year:

2013

Language:

english

File:

PDF, 6.17 MB

english, 2013

90

Preclinical models of multiple sclerosis in nonhuman primates

’t Hart, Bert A, Jagessar, S Anwar, Kap, Yolanda S, Brok, Herbert PM

Journal:

Expert Review of Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 501 KB

english, 2007

91

PDL241, a novel humanized monoclonal antibody, reveals CD319 as a therapeutic target for rheumatoid arthritis

Woo, Jacky, Vierboom, Michel PM, Kwon, Hakju, Chao, Debra, Ye, Shiming, Li, Jianmin, Lin, Karen, Tang, Irene, Belmar, Nicole A, Hartman, Taymar, Breedveld, Elia, Vexler, Vladimir, ‘t Hart, Bert A, Law

Journal:

Arthritis Research & Therapy

Year:

2013

Language:

english

File:

PDF, 875 KB

english, 2013

92

Improvement of preclinical animal models for autoimmune-mediated disorders via reverse translation of failed therapies

‘t Hart, Bert A., Jagessar, S. Anwar, Kap, Yolanda S., Haanstra, Krista G., Philippens, Ingrid H.C.H.M., Serguera, Che, Langermans, Jan, Vierboom, Michel

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 494 KB

english, 2014

93

Autoimmunity in non-human primates: the role of major histocompatibility complex and T cells, and implications for therapy

Jonker, Margreet, Bakker, Koos, Slierendregt, Bas, Hart, Bert 't, Bontrop, Ronald

Journal:

Human Immunology

Year:

1991

Language:

english

File:

PDF, 529 KB

english, 1991

94

Activation of encephalitogenic T cells in a MOG-induced marmoset EAE model is regulated by linked suppression

Dijkman, Karin, Jagessar, Anwar, Blezer, Erwin, Weissert, Robert, Hart, Bert 't

Journal:

Journal of Neuroimmunology

Year:

2014

Language:

english

File:

PDF, 48 KB

english, 2014

95

Selective manipulation of the CD28 Co-stimulation pathway prevents experimental autoimmune encephalomyelitis induction in the Rhesus Monkey

Haanstra, Krista, Dijkman, Karin, Van Driel, Nikki, Bashir, Noun, Bauer, Jan, Hart, Bert 't, Vanhove, Bernard

Journal:

Journal of Neuroimmunology

Year:

2014

Language:

english

File:

PDF, 49 KB

english, 2014

96

B cell depletion alters T cell homing

Kap, Yolanda, Van Driel, Nikki, Hart, Bert 't

Journal:

Journal of Neuroimmunology

Year:

2014

Language:

english

File:

PDF, 48 KB

english, 2014

97

Processing of MOG is affected by post-translational modification in virus infected non-human primate B cells

Jagessar, Anwar, Dijkman, Karin, Hofman, Sam, Heijmans, Nicole, Faber, Bart, Van Kasteren, Sander, Blorea, Bogdan, Hart, Bert 't

Journal:

Journal of Neuroimmunology

Year:

2014

Language:

english

File:

PDF, 48 KB

english, 2014

98

Feasibility of Adenovirus-Mediated Nonsurgical Synovectomy in Collagen-Induced Arthritis-Affected Rhesus Monkeys

Goossens, Paulien H., Schouten, Govert J., Hart, Bert A. 'T, Bout, Abraham, Brok, Herbert P.M., Kluin, Philip M., Breedveld, Ferdinand C., Valerio, Dinko, Huizinga, Tom W.J.

Journal:

Human Gene Therapy

Year:

1999

Language:

english

File:

PDF, 577 KB

english, 1999

99

Characterization of the natural immune response of rhesus monkey CD4+ve T cells to the bacterial antigen streptolysin O (SLO)

Kraakman, Elizabeth M., Bontrop, Ronald E., Groenesteln, Reno, Jonker, Margreet, Haaijman, Joost J., Hart, Bert A. ‘t

Journal:

Journal of Medical Primatology

Year:

1995

Language:

english

File:

PDF, 674 KB

english, 1995

100

Cytomegalovirus: a culprit or protector in multiple sclerosis?

Vanheusden, Marjan, Stinissen, Piet, ’t Hart, Bert A., Hellings, Niels

Journal:

Trends in Molecular Medicine

Year:

2015

Language:

english

File:

PDF, 987 KB

english, 2015