A. Pellagatti: search on Z-Library

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1

Application of CRISPR/Cas9 genome editing to the study and treatment of disease

Pellagatti, Andrea, Dolatshad, Hamid, Valletta, Simona, Boultwood, Jacqueline

Journal:

Archives of Toxicology

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

2

Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts

Papaemmanuil, E., Cazzola, M., Boultwood, J., Malcovati, L., Vyas, P., Bowen, D., Pellagatti, A., Wainscoat, J.S., Hellstrom-Lindberg, E., Gambacorti-Passerini, C., Godfrey, A.L., Rapado, I., Cvejic,

Journal:

Boston Medical and Surgical Journal

Year:

2011

Language:

english

File:

PDF, 865 KB

english, 2011

3

Mutations in SETBP1 are recurrent in myelodysplastic syndromes and often coexist with cytogenetic markers associated with disease progression

Fernandez-Mercado, Marta, Pellagatti, Andrea, Di Genua, Cristina, Larrayoz, Maria Jose, Winkelmann, Nils, Aranaz, Paula, Burns, Adam, Schuh, Anna, Calasanz, Maria Jose, Cross, Nicholas C. P., Boultwoo

Journal:

British Journal of Haematology

Year:

2013

Language:

english

File:

PDF, 72 KB

english, 2013

4

A novel polymorphism (219G>A) in the transferrin receptor gene

Mirella Meregalli, Noemi Corbetta, Andrea Pellagatti, Franco Martinez di Montemuros, Dario Tavazzi, Silvia Fargion, Maurizio Sampietro

Journal:

Year:

2000

Language:

english

File:

PDF, 10 KB

english, 2000

5

Molecular analysis of the TFR2 gene: Report of a novel polymorphism (1878C>T)

Mirella Meregalli, Andrea Pellagatti, Elena Bissolotti, Anna Ludovica Fracanzani, Silvia Fargion, Maurizio Sampietro

Journal:

Year:

2000

Language:

english

File:

PDF, 9 KB

english, 2000

6

C023 Expression profiling of CD34+ cells in patients with myelodysplastic syndromes: differences between early and advanced cases and analysis of apoptosis-related genes

A. Pellagatti, M. Cazzola, A. Giagounidis, L. Malcovati, M.G. Della Porta, M. Jädersten, S. Killick, C. Fidler, H. Cattan, D. Bowen, C. Aul, E. Hellström-Lindberg, J.S. Wainscoat, J. Boultwood

Journal:

Leukemia Research

Year:

2007

Language:

english

File:

PDF, 52 KB

english, 2007

7

YI1 Gene expression profiling of day 7 erythroblasts from refractory anemia with ringed sideroblasts (RARS) and microarray-based identification of erythroid granulocyte-CSF (G-CSF) targets

M. Nikpour, A. Pellagatti, A. Liu, M. Karimi, L. Malcovati, A.-M. Forsblom, V. Gogvadze, J.S. Wainscoat, M. Cazzola, B. Zhivotovsky, A. Grandien, J. Boultwood, E. Hellström-Lindberg

Journal:

Leukemia Research

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

8

27 Molecular pathogenesis of the 5q- syndrome

Journal:

Leukemia Research

Year:

2011

Language:

english

File:

PDF, 50 KB

english, 2011

9

Gene expression profiling in the myelodysplastic syndromes using cDNA microarray technology

Andrea Pellagatti, Noor Esoof, Fiona Watkins, Cordelia F. Langford, David Vetrie, Lisa J. Campbell, Carrie Fidler, James D. Cavenagh, Helen Eagleton, Peter Gordon, Barrie Woodcock, Beena Pushkaran, Ma

Journal:

British Journal of Haematology

Year:

2004

Language:

english

File:

PDF, 260 KB

english, 2004

10

Low expression of the putative tumour suppressor gene gravin in chronic myeloid leukaemia, myelodysplastic syndromes and acute myeloid leukaemia

Jacqueline Boultwood, Andrea Pellagatti, Fiona Watkins, Lisa J. Campbell, Noor Esoof, Nicholas C. P. Cross, Helen Eagleton, Tim J. Littlewood, Carrie Fidler, James S. Wainscoat

Journal:

British Journal of Haematology

Year:

2004

Language:

english

File:

PDF, 105 KB

english, 2004

11

Gene expression profiling of CD34+ cells in patients with the 5q− syndrome

Jacqueline Boultwood, Andrea Pellagatti, Helen Cattan, Charles H. Lawrie, Aristoteles Giagounidis, Luca Malcovati, Matteo G. Della Porta, Martin Jädersten, Sally Killick, Carrie Fidler, Mario Cazzola,

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 521 KB

english, 2007

12

Haploinsufficiency of RPS14 in 5q− syndrome is associated with deregulation of ribosomal- and translation-related genes

Andrea Pellagatti, Eva Hellström-Lindberg, Aristoteles Giagounidis, Janet Perry, Luca Malcovati, Matteo G. Della Porta, Martin Jädersten, Sally Killick, Carrie Fidler, Mario Cazzola, James S. Wainscoa

Journal:

British Journal of Haematology

Year:

2008

Language:

english

File:

PDF, 360 KB

english, 2008

13

Marked downregulation of the granulopoiesis regulator LEF1 is associated with disease progression in the myelodysplastic syndromes

Andrea Pellagatti, Teresa Marafioti, Jennifer C. Paterson, Luca Malcovati, Matteo G. Della Porta, Martin Jädersten, Beena Pushkaran, Tracy I. George, Daniel A. Arber, Sally Killick, Aristoteles Giagou

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 242 KB

english, 2009

14

Gene expression profiling of erythroblasts from refractory anaemia with ring sideroblasts (RARS) and effects of G-CSF

Maryam Nikpour, Andrea Pellagatti, Anquan Liu, Mohsen Karimi, Luca Malcovati, Vladimir Gogvadze, Ann-Mari Forsblom, James S. Wainscoat, Mario Cazzola, Boris Zhivotovsky, Alf Grandien, Jacqueline Boult

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 598 KB

english, 2010

15

Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome

Andrea Pellagatti, Mario Cazzola, Aristoteles Giagounidis, Janet Perry, Luca Malcovati, Matteo G. Della Porta, Martin Jädersten, Sally Killick, Paresh Vyas, Eva Hellström-Lindberg, James S. Wainscoat,

Journal:

British Journal of Haematology

Year:

2011

Language:

english

File:

PDF, 77 KB

english, 2011

16

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia

Boultwood, J, Perry, J, Pellagatti, A, Fernandez-Mercado, M, Fernandez-Santamaria, C, Calasanz, M J, Larrayoz, M J, Garcia-Delgado, M, Giagounidis, A, Malcovati, L

Journal:

Year:

2010

Language:

english

File:

PDF, 300 KB

english, 2010

17

Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells

Pellagatti, A, Cazzola, M, Giagounidis, A, Perry, J, Malcovati, L, Della Porta, M G, Jädersten, M, Killick, S, Verma, A, Norbury, C J

Journal:

Year:

2010

Language:

english

File:

PDF, 521 KB

english, 2010

18

High-density single nucleotide polymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression

Boultwood, J, Perry, J, Zaman, R, Fernandez-Santamaria, C, Littlewood, T, Kusec, R, Pellagatti, A, Wang, L, Clark, R E, Wainscoat, J S

Journal:

Year:

2010

Language:

english

File:

PDF, 305 KB

english, 2010

19

Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the α-thalassemia myelodysplasia syndrome (ATMDS)

Gibbons, Richard J, Pellagatti, Andrea, Garrick, David, Wood, William G, Malik, Nicola, Ayyub, Helena, Langford, Cordelia, Boultwood, Jacqueline, Wainscoat, James S, Higgs, Douglas R

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 585 KB

english, 2003

20

Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis

Jerez, A., Sugimoto, Y., Makishima, H., Verma, A., Jankowska, A. M., Przychodzen, B., Visconte, V., Tiu, R. V., O'Keefe, C. L., Mohamedali, A. M., Kulasekararaj, A. G., Pellagatti, A., McGraw, K., Mur

Journal:

Year:

2012

Language:

english

File:

PDF, 665 KB

english, 2012

21

Haploinsufficiency of ribosomal proteins and p53 activation in anemia: Diamond-Blackfan anemia and the 5q- syndrome

Jacqueline Boultwood, Andrea Pellagatti, James S. Wainscoat

Journal:

Advances in Biological Regulation

Year:

2012

Language:

english

File:

PDF, 227 KB

english, 2012

22

The hemochromatosis gene affects the age of onset of sporadic Alzheimer’s disease

M. Sampietro, L. Caputo, A. Casatta, M. Meregalli, A. Pellagatti, J. Tagliabue, G. Annoni, C. Vergani

Journal:

Neurobiology of Aging

Year:

2001

Language:

english

File:

PDF, 130 KB

english, 2001

23

Identification of Gene Expression-Based Prognostic Markers in the Hematopoietic Stem Cells of Patients With Myelodysplastic Syndromes

Pellagatti, A., Benner, A., Mills, K. I., Cazzola, M., Giagounidis, A., Perry, J., Malcovati, L., Della Porta, M. G., Jadersten, M., Verma, A., McDonald, E.-J., Killick, S., Hellstrom-Lindberg, E., Bu

Journal:

Journal of Clinical Oncology

Year:

2013

Language:

english

File:

PDF, 291 KB

english, 2013

24

TP53 suppression promotes erythropoiesis in del(5q) MDS, suggesting a targeted therapeutic strategy in lenalidomide-resistant patients

Caceres, G., McGraw, K., Yip, B. H., Pellagatti, A., Johnson, J., Zhang, L., Liu, K., Zhang, L. M., Fulp, W. J., Lee, J.-H., Al Ali, N. H., Basiorka, A., Smith, L. J., Daugherty, F. J., Littleton, N.,

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

25

The role of splicing factor mutations in the pathogenesis of the myelodysplastic syndromes

Boultwood, Jacqueline, Dolatshad, Hamid, Varanasi, Satya S., Yip, Bon Ham, Pellagatti, Andrea

Journal:

Advances in Biological Regulation

Year:

2014

Language:

english

File:

PDF, 908 KB

english, 2014

26

Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

Savage, Kienan I., Gorski, Julia J., Barros, Eliana M., Irwin, Gareth W., Manti, Lorenzo, Powell, Alexander J., Pellagatti, Andrea, Lukashchuk, Natalia, McCance, Dennis J., McCluggage, W. Glenn, Schet

Journal:

Year:

2014

Language:

english

File:

PDF, 4.22 MB

english, 2014

27

Activation of the mTOR pathway by the amino acid l-leucine in the 5q- syndrome and other ribosomopathies

Boultwood, Jacqueline, Yip, Bon Ham, Vuppusetty, Chaitanya, Pellagatti, Andrea, Wainscoat, James S.

Journal:

Advances in Biological Regulation

Year:

2013

Language:

english

File:

PDF, 511 KB

english, 2013

28

P-105 Loss of proliferative phenotype and expression of CDKN1C/p57KIP2 in CD34+ cells predict poor prognosis of MDS

Dietrich, S., Andrulis, M., Benner, A., Pellagatti, A., Giese, T., Germing, U., Baldus, S., Boultwood, J., Radujkovic, A., Dreger, P., Ho, A.D., Luft, T.

Journal:

Leukemia Research

Year:

2013

Language:

english

File:

PDF, 141 KB

english, 2013

29

Reduced translation of GATA1 in Diamond-Blackfan anemia

Boultwood, Jacqueline, Pellagatti, Andrea

Journal:

Nature Medicine

Year:

2014

Language:

english

File:

PDF, 1.05 MB

english, 2014

30

Whole-exome sequencing in del(5q) myelodysplastic syndromes in transformation to acute myeloid leukemia

Pellagatti, A, Fernandez-Mercado, M, Di Genua, C, Larrayoz, M J, Killick, S, Dolatshad, H, Burns, A, Calasanz, M J, Schuh, A, Boultwood, J

Journal:

Year:

2014

Language:

english

File:

PDF, 282 KB

english, 2014

31

Clinical and biological implications of driver mutations in myelodysplastic syndromes

Papaemmanuil, E., Gerstung, M., Malcovati, L., Tauro, S., Gundem, G., Van Loo, P., Yoon, C. J., Ellis, P., Wedge, D. C., Pellagatti, A., Shlien, A., Groves, M. J., Forbes, S. A., Raine, K., Hinton, J.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.57 MB

english, 2013

32

Effects of L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts

Yip, B H, Pellagatti, A, Vuppusetty, C, Giagounidis, A, Germing, U, Lamikanra, A A, Roberts, D J, Fernandez-Mercado, M, McDonald, E-J, Killick, S, Wainscoat, J S, Boultwood, J

Journal:

Year:

2012

Language:

english

File:

PDF, 393 KB

english, 2012

33

Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

Dolatshad, H, Pellagatti, A, Fernandez-Mercado, M, Yip, B H, Malcovati, L, Attwood, M, Przychodzen, B, Sahgal, N, Kanapin, A A, Lockstone, H, Scifo, L, Vandenberghe, P, Papaemmanuil, E, Smith, C W J,

Journal:

Year:

2015

Language:

english

File:

PDF, 1.37 MB

english, 2015

34

Activation of the mTOR signaling pathway by L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts

Yip, B H, Vuppusetty, C, Attwood, M, Giagounidis, A, Germing, U, Lamikanra, A A, Roberts, D J, Maciejewski, J P, Vandenberghe, P, Mecucci, C, Wainscoat, J S, Pellagatti, A, Boultwood, J

Journal:

Year:

2013

Language:

english

File:

PDF, 1.18 MB

english, 2013

35

Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes

Gerstung, Moritz, Pellagatti, Andrea, Malcovati, Luca, Giagounidis, Aristoteles, Porta, Matteo G Della, Jädersten, Martin, Dolatshad, Hamid, Verma, Amit, Cross, Nicholas C. P., Vyas, Paresh, Killick,

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 1.64 MB

english, 2015

36

Silencing of ASXL1 impairs the granulomonocytic lineage potential of human CD34 + progenitor cells

Davies, Carwyn, Yip, Bon Ham, Fernandez-Mercado, Marta, Woll, Petter S., Agirre, Xabier, Prosper, Felipe, Jacobsen, Sten E., Wainscoat, James S., Pellagatti, Andrea, Boultwood, Jacqueline

Journal:

British Journal of Haematology

Year:

2013

Language:

english

File:

PDF, 417 KB

english, 2013

37

The molecular pathogenesis of the myelodysplastic syndromes

Pellagatti, Andrea, Boultwood, Jacqueline

Journal:

European Journal of Haematology

Year:

2015

Language:

english

File:

PDF, 293 KB

english, 2015

38

Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients

Pellagatti, A., Jadersten, M., Forsblom, A.-M., Cattan, H., Christensson, B., Emanuelsson, E. K., Merup, M., Nilsson, L., Samuelsson, J., Sander, B., Wainscoat, J. S., Boultwood, J., Hellstrom-Lindber

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 1.00 MB

english, 2007

39

52 TARGETED RE-SEQUENCING ANALYSIS OF 31 GENES COMMONLY MUTATED IN MYELOID DISORDERS IN SERIAL SAMPLES FROM MYELODYSPLASTIC SYNDROME PATIENTS WITH DISEASE PROGRESSION

Pellagatti, A., Roy, S., Di Genua, C., Burns, A., McGraw, K., Larrayoz, M.J., Fernandez-Mercado, M., Valletta, S., Mason, J., Killick, S., Mecucci, C., Calasanz, M.J., List, A., Schuh, A., Boultwood,

Journal:

Leukemia Research

Year:

2015

Language:

english

File:

PDF, 194 KB

english, 2015

40

Mutation Patterns of 16 Genes in Primary and Secondary Acute Myeloid Leukemia (AML) with Normal Cytogenetics

Fernandez-Mercado, Marta, Yip, Bon Ham, Pellagatti, Andrea, Davies, Carwyn, Larrayoz, María José, Kondo, Toshinori, Pérez, Cristina, Killick, Sally, McDonald, Emma-Jane, Odero, María Dolores, Agirre,

Journal:

Year:

2012

Language:

english

File:

PDF, 250 KB

english, 2012

41

IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells

Schinke, C., Giricz, O., Li, W., Shastri, A., Gordon, S., Barreyro, L., Bhagat, T., Bhattacharyya, S., Ramachandra, N., Bartenstein, M., Pellagatti, A., Boultwood, J., Wickrema, A., Yu, Y., Will, B.,

Journal:

Year:

2015

Language:

english

File:

PDF, 2.59 MB

english, 2015

42

High and low, but not intermediate, PRAME expression levels are poor prognostic markers in myelodysplastic syndrome at disease presentation

Liberante, Fabio G., Pellagatti, Andrea, Boncheva, Viktoriya, Bowen, David T., Mills, Ken I., Boultwood, Jacqueline, Guinn, Barbara-Ann

Journal:

British Journal of Haematology

Year:

2013

Language:

english

File:

PDF, 148 KB

english, 2013

43

The G-Protein-Coupled Receptor CLR Is Upregulated in an Autocrine Loop with Adrenomedullin in Clear Cell Renal Cell Carcinoma and Associated with Poor Prognosis

Nikitenko, L. L., Leek, R., Henderson, S., Pillay, N., Turley, H., Generali, D., Gunningham, S., Morrin, H. R., Pellagatti, A., Rees, M. C. P., Harris, A. L., Fox, S. B.

Journal:

Clinical Cancer Research

Year:

2013

Language:

english

File:

PDF, 1.02 MB

english, 2013

44

Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

Dolatshad, H, Pellagatti, A, Fernandez-Mercado, M, Yip, B H, Malcovati, L, Attwood, M, Przychodzen, B, Sahgal, N, Kanapin, A A, Lockstone, H, Scifo, L, Vandenberghe, P, Papaemmanuil, E, Smith, C W J,

Journal:

Year:

2015

File:

PDF, 57 KB

2015

45

Application of genome editing technologies to the study and treatment of hematological disease

Pellagatti, Andrea, Dolatshad, Hamid, Yip, Bon Ham, Valletta, Simona, Boultwood, Jacqueline

Journal:

Advances in Biological Regulation

Year:

2015

Language:

english

File:

PDF, 748 KB

english, 2015

46

Targeted resequencing analysis of 31 genes commonly mutated in myeloid disorders in serial samples from myelodysplastic syndrome patients showing disease progression

Pellagatti, A, Roy, S, Di Genua, C, Burns, A, McGraw, K, Valletta, S, Larrayoz, M J, Fernandez-Mercado, M, Mason, J, Killick, S, Mecucci, C, Calasanz, M J, List, A, Schuh, A, Boultwood, J

Journal:

Year:

2015

Language:

english

File:

PDF, 430 KB

english, 2015

47

Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes

Fernandez-Mercado, M., Burns, A., Pellagatti, A., Giagounidis, A., Germing, U., Agirre, X., Prosper, F., Aul, C., Killick, S., Wainscoat, J. S., Schuh, A., Boultwood, J.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013

48

Clinical associations of CSNK1A1 mutation in myelodysplastic syndrome

Boultwood, Jacqueline, Pellagatti, Andrea

Journal:

The Lancet Haematology

Year:

2015

Language:

english

File:

PDF, 105 KB

english, 2015

49

Gene expression profiling in the myelodysplastic syndromes

Pellagatti, Andrea, Fidler, Carrie, Wainscoat, James S., Boultwood, Jacqueline

Journal:

Hematology (American Society of Hematology)

Year:

2005

Language:

english

File:

PDF, 317 KB

english, 2005

50

Cryptic splicing events in the iron transporter ABCB7 and other key target genes in SF3B1 mutant myelodysplastic syndromes

Dolatshad, H, Pellagatti, A, Liberante, F G, Llorian, M, Repapi, E, Steeples, V, Roy, S, Scifo, L, Armstrong, R N, Shaw, J, Yip, B H, Killick, S, Kušec, R, Taylor, S, Mills, K I, Savage, K I, Smith, C

Journal:

Year:

2016

Language:

english

File:

PDF, 2.54 MB

english, 2016