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1

Effect of KRAS and BRAF Mutations on Survival of Metastatic Colorectal Cancer After Liver Resection: A Systematic Review and Meta-Analysis

Tosi, Federica, Magni, Elena, Amatu, Alessio, Mauri, Gianluca, Bencardino, Katia, Truini, Mauro, Veronese, Silvio, De Carlis, Luciano, Ferrari, Giovanni, Nichelatti, Michele, Sartore-Bianchi, Andrea,

Journal:

Clinical Colorectal Cancer

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

2

The right chance for temozolomide in metastatic colorectal cancer?

Sartore-Bianchi, Andrea, Siena, Salvatore

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 170 KB

english, 2018

3

Plasma HER2 ( ERBB2 ) copy number predicts response to HER2-targeted therapy in metastatic colorectal cancer

Siravegna, Giulia, Sartore-Bianchi, Andrea, Nagy, Rebecca J., Raghav, Kanwal, Odegaard, Justin I, Lanman, Richard B., Trusolino, Livio, Marsoni, Silvia, Siena, Salvatore, Bardelli, Alberto

Journal:

Clinical Cancer Research

Year:

2019

Language:

english

File:

PDF, 942 KB

english, 2019

4

Gemcitabine and oxaliplatin in the treatment of patients with immunotherapy-resistant advanced renal cell carcinoma : Final results of a single-institution Phase II study

Camillo Porta, Matteo Zimatore, Ilaria Imarisio, Anna Natalizi, Andrea Sartore-Bianchi, Marco Danova, Alberto Riccardi

Journal:

Year:

2004

Language:

english

File:

PDF, 171 KB

english, 2004

5

Controversial evaluation of EGFR protein and gene status in predicting response to anti-EGFR monoclonal antibodies in metastatic colorectal cancer: a case report and review of the literature

Mauro Moroni, Silvio Veronese, Andrea Sartore-Bianchi, Salvatore Artale, Salvatore Siena

Journal:

Targeted Oncology

Year:

2008

Language:

english

File:

PDF, 277 KB

english, 2008

6

Integrated molecular dissection of the epidermal growth factor receptor (EFGR) oncogenic pathway to predict response to EGFR-targeted monoclonal antibodies in metastatic colorectal cancer

Andrea Sartore-Bianchi, Katia Bencardino, Federica Di Nicolantonio, Federico Pozzi, Chiara Funaioli, Valentina Gambi, Sabrina Arena, Miriam Martini, Simona Lamba, Andrea Cassingena, Roberta Schiavo, A

Journal:

Targeted Oncology

Year:

2010

Language:

english

File:

PDF, 503 KB

english, 2010

7

Correspondence

A. Sartore-Bianchi, P. Pedrazzoli, L. Ponchio, A. Lanza, L. Pavesi

Journal:

Clinical Oncology

Year:

2002

Language:

english

File:

PDF, 43 KB

english, 2002

8

Therapeutic implications of resistance to molecular therapies in metastatic colorectal cancer

A. Sartore-Bianchi, K. Bencardino, A. Cassingena, F. Venturini, C. Funaioli, T. Cipani, A. Amatu, L. Pietrogiovanna, R. Schiavo, F. Di Nicolantonio, S. Artale, A. Bardelli, S. Siena

Journal:

Cancer Treatment Reviews

Year:

2010

Language:

english

File:

PDF, 102 KB

english, 2010

9

Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

Mauro Moroni, Silvio Veronese, Silvia Benvenuti, Giovanna Marrapese, Andrea Sartore-Bianchi, Federica Di Nicolantonio, Marcello Gambacorta, Salvatore Siena, Alberto Bardelli

Journal:

The Lancet Oncology

Year:

2005

Language:

english

File:

PDF, 332 KB

english, 2005

10

EGFR FISH in colorectal cancer: what is the current reality?

Mauro Moroni, Andrea Sartore-Bianchi, Silvio Veronese, Salvatore Siena

Journal:

The Lancet Oncology

Year:

2008

Language:

english

File:

PDF, 186 KB

english, 2008

11

Intrapleural interleukin-2 induces nitric oxide production in pleural effusions from malignant mesothelioma: A possible mechanism of interleukin-2-mediated cytotoxicity?

Porta, Camillo, Rizzo, Vittoria, Zimatore, Matteo, Sartore-Bianchi, Andrea, Danova, Marco, Mutti, Luciano

Journal:

Year:

2002

Language:

english

File:

PDF, 103 KB

english, 2002

12

Erratum to: Integrated molecular dissection of the epidermal growth factor receptor (EGFR) oncogenic pathway to predict response to EGFR-targeted monoclonal antibodies in metastatic colorectal cancer

Andrea Sartore-Bianchi, Katia Bencardino, Federica Di Nicolantonio, Federico Pozzi, Chiara Funaioli, Valentina Gambi, Sabrina Arena, Miriam Martini, Simona Lamba, Andrea Cassingena, Roberta Schiavo, A

Journal:

Targeted Oncology

Year:

2012

File:

PDF, 46 KB

2012

13

Is Codon 13KRASMutation Biologically Different from Codon 12 Mutation?

Alessio Amatu, Andrea Sartore-Bianchi, Katia Bencardino, Andrea Cassingena, Filippo Venturini, Felicia Giacobbe, Lisa Pietrogiovanna, Giovanna Marrapese, Alessandra Gambaro, Alessandro Belotti, Salvat

Journal:

Current Colorectal Cancer Reports

Year:

2012

Language:

english

File:

PDF, 132 KB

english, 2012

14

Raltitrexed–Oxaliplatin combination chemotherapy is inactive as second-line treatment for malignant pleural mesothelioma patients

Porta, Camillo, Zimatore, Matteo, Bonomi, Lucia, Imarisio, Ilaria, Paglino, Chiara, Sartore-Bianchi, Andrea, Mutti, Luciano

Journal:

Year:

2005

Language:

english

File:

PDF, 100 KB

english, 2005

15

PIK3CA Mutations in Colorectal Cancer Are Associated with Clinical Resistance to EGFR-Targeted Monoclonal Antibodies

Sartore-Bianchi, A., Martini, M., Molinari, F., Veronese, S., Nichelatti, M., Artale, S., Di Nicolantonio, F., Saletti, P., De Dosso, S., Mazzucchelli, L., Frattini, M., Siena, S., Bardelli, A.

Journal:

Cancer Research

Year:

2009

Language:

english

File:

PDF, 431 KB

english, 2009

16

KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy

Valtorta, Emanuele, Misale, Sandra, Sartore-Bianchi, Andrea, Nagtegaal, Iris D., Paraf, François, Lauricella, Calogero, Dimartino, Valentina, Hobor, Sebastijan, Jacobs, Bart, Ercolani, Cristiana, Lamb

Journal:

International Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 367 KB

english, 2013

17

Regorafenib for metastatic colorectal cancer

Ricotta, Riccardo, Sartore-Bianchi, Andrea, Verrioli, Antonella, Vanzulli, Angelo, Siena, Salvatore

Journal:

Year:

2013

Language:

english

File:

PDF, 40 KB

english, 2013

18

Panitumumab in combination with infusional oxaliplatin and oral capecitabine for conversion therapy in patients with colon cancer and advanced liver metastases

Leone, Francesco, Artale, Salvatore, Marino, Donatella, Cagnazzo, Celeste, Cascinu, Stefano, Pinto, Carmine, Fornarini, Giuseppe, Tampellini, Marco, Di Fabio, Francesca, Sartore-Bianchi, Andrea, De Ca

Journal:

Year:

2013

Language:

english

File:

PDF, 274 KB

english, 2013

19

Acquired resistance to EGFR-targeted therapies in colorectal cancer

Van Emburgh, Beth O., Sartore-Bianchi, Andrea, Di Nicolantonio, Federica, Siena, Salvatore, Bardelli, Alberto

Journal:

Molecular Oncology

Year:

2014

Language:

english

File:

PDF, 1.15 MB

english, 2014

20

Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer

Bardelli, A., Corso, S., Bertotti, A., Hobor, S., Valtorta, E., Siravegna, G., Sartore-Bianchi, A., Scala, E., Cassingena, A., Zecchin, D., Apicella, M., Migliardi, G., Galimi, F., Lauricella, C., Zan

Journal:

Cancer Discovery

Year:

2013

Language:

english

File:

PDF, 5.95 MB

english, 2013

21

Resistance to Anti-EGFR Therapy in Colorectal Cancer: From Heterogeneity to Convergent Evolution

Misale, S., Di Nicolantonio, F., Sartore-Bianchi, A., Siena, S., Bardelli, A.

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 3.20 MB

english, 2014

22

Mutations of KRAS and BRAF in Primary and Matched Metastatic Sites of Colorectal Cancer

Artale, S., Sartore-Bianchi, A., Veronese, S. M., Gambi, V., Sarnataro, C. S., Gambacorta, M., Lauricella, C., Siena, S.

Journal:

Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 68 KB

english, 2008

23

Epigenetic Inactivation of the BRCA1 Interactor SRBC and Resistance to Oxaliplatin in Colorectal Cancer

Moutinho, C., Martinez-Cardus, A., Santos, C., Navarro-Perez, V., Martinez-Balibrea, E., Musulen, E., Carmona, F. J., Sartore-Bianchi, A., Cassingena, A., Siena, S., Elez, E., Tabernero, J., Salazar,

Journal:

JNCI Journal of the National Cancer Institute

Year:

2014

Language:

english

File:

PDF, 5.86 MB

english, 2014

24

Biomarkers Predicting Clinical Outcome of Epidermal Growth Factor Receptor-Targeted Therapy in Metastatic Colorectal Cancer

Siena, S., Sartore-Bianchi, A., Di Nicolantonio, F., Balfour, J., Bardelli, A.

Journal:

JNCI Journal of the National Cancer Institute

Year:

2009

Language:

english

File:

PDF, 828 KB

english, 2009

25

Oncogenic Activation of the RAS/RAF Signaling Pathway Impairs the Response of Metastatic Colorectal Cancers to Anti-Epidermal Growth Factor Receptor Antibody Therapies

Benvenuti, S., Sartore-Bianchi, A., Di Nicolantonio, F., Zanon, C., Moroni, M., Veronese, S., Siena, S., Bardelli, A.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 309 KB

english, 2007

26

Wild-Type BRAF Is Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer

Di Nicolantonio, F., Martini, M., Molinari, F., Sartore-Bianchi, A., Arena, S., Saletti, P., De Dosso, S., Mazzucchelli, L., Frattini, M., Siena, S., Bardelli, A.

Journal:

Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 261 KB

english, 2008

27

54 MGMT methylation assessed by methyl-BEAMing technique is a prognostic and predictive biomarker in glioblastoma and metastatic colorectal cancer patients

Barault, L., Amatu, A., Bleeker, F.E., Moutinho, C., Cassingena, A., Tosi, F., Venesio, T., Esteller, M., Bardelli, A., Siena, S., Sartore-Bianchi, A., Di Nicolantonio, F.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 54 KB

english, 2014

28

Regorafenib in metastatic colorectal cancer

Sartore-Bianchi, Andrea, Zeppellini, Annalisa, Amatu, Alessio, Ricotta, Riccardo, Bencardino, Katia, Siena, Salvatore

Journal:

Expert Review of Anticancer Therapy

Year:

2014

Language:

english

File:

PDF, 580 KB

english, 2014

29

Bortezomib Inhibits Nuclear Factor- B Dependent Survival and Has Potent In vivo Activity in Mesothelioma

Sartore-Bianchi, A., Gasparri, F., Galvani, A., Nici, L., Darnowski, J. W., Barbone, D., Fennell, D. A., Gaudino, G., Porta, C., Mutti, L.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 531 KB

english, 2007

30

Promoter CpG Island Hypermethylation of the DNA Repair Enzyme MGMT Predicts Clinical Response to Dacarbazine in a Phase II Study for Metastatic Colorectal Cancer

Amatu, A., Sartore-Bianchi, A., Moutinho, C., Belotti, A., Bencardino, K., Chirico, G., Cassingena, A., Rusconi, F., Esposito, A., Nichelatti, M., Esteller, M., Siena, S.

Journal:

Clinical Cancer Research

Year:

2013

Language:

english

File:

PDF, 616 KB

english, 2013

31

Standardisation of EGFR FISH in colorectal cancer: results of an international interlaboratory reproducibility ring study

Sartore-Bianchi, A., Fieuws, S., Veronese, S., Moroni, M., Personeni, N., Frattini, M., Torri, V., Cappuzzo, F., Borght, S. V., Martin, V., Skokan, M., Santoro, A., Gambacorta, M., Tejpar, S., Varella

Journal:

Journal of Clinical Pathology

Year:

2012

Language:

english

File:

PDF, 428 KB

english, 2012

32

In Reply

Sartore-Bianchi, A., Artale, S., Veronese, S., Gambacorta, M., Siena, S.

Journal:

Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

33

Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer

Misale, S., Arena, S., Lamba, S., Siravegna, G., Lallo, A., Hobor, S., Russo, M., Buscarino, M., Lazzari, L., Sartore-Bianchi, A., Bencardino, K., Amatu, A., Lauricella, C., Valtorta, E., Siena, S., D

Journal:

Science Translational Medicine

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

34

Association of KRAS p.G13D Mutation With Outcome in Patients With Chemotherapy-Refractory Metastatic Colorectal Cancer Treated With Cetuximab

De Roock, Wendy, Jonker, Derek J., Di Nicolantonio, Federica, Sartore-Bianchi, Andrea, Tu, Dongsheng, Siena, Salvatore, Lamba, Simona, Arena, Sabrina, Frattini, Milo, Piessevaux, Hubert, Van Cutsem, E

Journal:

JAMA The Journal of the American Medical Association

Year:

2010

Language:

english

File:

PDF, 503 KB

english, 2010

35

Epidermal Growth Factor Receptor Gene Copy Number and Clinical Outcome of Metastatic Colorectal Cancer Treated With Panitumumab

Sartore-Bianchi, A., Moroni, M., Veronese, S., Carnaghi, C., Bajetta, E., Luppi, G., Sobrero, A., Barone, C., Cascinu, S., Colucci, G., Cortesi, E., Nichelatti, M., Gambacorta, M., Siena, S.

Journal:

Journal of Clinical Oncology

Year:

2007

Language:

english

File:

PDF, 330 KB

english, 2007

36

Response: Re: Biomarkers Predicting Clinical Outcome of Epidermal Growth Factor Receptor-Targeted Therapy in Metastatic Colorectal Cancer

Siena, S., Sartore-Bianchi, A., di Nicolantonio, F., Balfour, J., Bardelli, A.

Journal:

JNCI Journal of the National Cancer Institute

Year:

2010

Language:

english

File:

PDF, 99 KB

english, 2010

37

Epidermal Growth Factor Receptor-Targeted Therapy of Colorectal Cancer with Panitumumab

Sartore-Bianchi, Andrea, Sporchia, Andrea, Cerea, Giulio, Maugeri, Maria, Cipani, Tiziana, Andreotti, Ines, Marrapese, Giovanna, Artale, Salvatore, Siena, Salvatore

Journal:

Current Cancer Therapy Reviews

Year:

2007

Language:

english

File:

PDF, 300 KB

english, 2007

38

Effects of Cancer Therapy Targeting Vascular Endothelial Growth Factor Receptor on Central Blood Pressure and Cardiovascular System

Moreo, A., Vallerio, P., Ricotta, R., Stucchi, M., Pozzi, M., Musca, F., Meani, P., Maloberti, A., Facchetti, R., Di Bella, S., Giganti, M. O., Sartore-Bianchi, A., Siena, S., Mancia, G., Giannattasio

Journal:

American Journal of Hypertension

Year:

2015

Language:

english

File:

PDF, 538 KB

english, 2015

39

Anti-EGFR monoclonal antibodies in the treatment of non-small cell lung cancer

Sartore-Bianchi, A., Cerea, G., Schiavetto, I., Giannetta, L., Ricotta, R., Maugeri, M. R., Moroni, M., Marrapese, G., Siena, S.

Journal:

Annals of Oncology

Year:

2006

Language:

english

File:

PDF, 45 KB

english, 2006

40

BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis

Cremolini, C., Di Bartolomeo, M., Amatu, A., Antoniotti, C., Moretto, R., Berenato, R., Perrone, F., Tamborini, E., Aprile, G., Lonardi, S., Sartore-Bianchi, A., Fontanini, G., Milione, M., Lauricella

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

41

Assessment of a HER2 scoring system for colorectal cancer: results from a validation study

E. Valtorta, C. Martino, A. Sartore-bianchi, F. Penaullt-llorca, G. Viale, M. Risio, M. Rugge, W. Grigioni, K. Bencardino, S. Lonardi, V. Zagonel, F. Leone, J. Noe, F. Ciardiello, C. Pinto, R. Labianc

Year:

2015

Language:

english

File:

PDF, 2.81 MB

english, 2015

42

Translational challenges from the 2014 Gastrointestinal Cancers Symposium: toward a true tailored therapy through effective research

Aprile, Giuseppe, Giuliani, Francesco, Cordio, Stefano, Sartore-Bianchi, Andrea, Bencardino, Katia, Ongaro, Elena, Martines, Concetta, Giampieri, Riccardo, Bordonaro, Roberto, Siena, Salvatore, Cascin

Journal:

Future Oncology

Year:

2014

Language:

english

File:

PDF, 1.62 MB

english, 2014

43

Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer

Sartore-Bianchi, A., Ardini, E., Bosotti, R., Amatu, A., Valtorta, E., Somaschini, A., Raddrizzani, L., Palmeri, L., Banfi, P., Bonazzina, E., Misale, S., Marrapese, G., Leone, A., Alzani, R., Luo, D.

Journal:

JNCI Journal of the National Cancer Institute

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

44

Linitis Plastica of the Rectum As a Clinical Presentation of Metastatic Lobular Carcinoma of the Breast

Venturini, F., Gambi, V., Di Lernia, S., Vanzulli, A., Bramerio, M., Bencardino, K., Amatu, A., Cipani, T., Forti, E., Tarenzi, E., Sartore-Bianchi, A., Pugliese, R., Siena, S.

Journal:

Journal of Clinical Oncology

Year:

2014

Language:

english

File:

PDF, 463 KB

english, 2014

45

New frontiers in therapeutic resistance in cancer

Sartore-Bianchi, Andrea, Delorenzi, Mauro, Gagnon-Kugler, Thérèse, Rousseau, Caroline, Batist, Gerald

Journal:

Expert Review of Anticancer Therapy

Year:

2012

Language:

english

File:

PDF, 334 KB

english, 2012

46

Oxaliplatin immune-induced syndrome occurs with cumulative administration and rechallenge: single Institution series and a systematic review study

Bencardino, Katia, Mauri, Gianluca, Amatu, Alessio, Tosi, Federica, Bonazzina, Erica, Palmeri, Laura, Querques, Marialuisa, Ravera, Federica, Menegotto, Alberto, Boiani, Elisa, Sartore-Bianchi, Andrea

Journal:

Clinical Colorectal Cancer

Year:

2016

Language:

english

File:

PDF, 1.50 MB

english, 2016

47

Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial

Sartore-Bianchi, Andrea, Trusolino, Livio, Martino, Cosimo, Bencardino, Katia, Lonardi, Sara, Bergamo, Francesca, Zagonel, Vittorina, Leone, Francesco, Depetris, Ilaria, Martinelli, Erika, Troiani, Te

Journal:

The Lancet Oncology

Year:

2016

Language:

english

File:

PDF, 295 KB

english, 2016

48

Challenging chemoresistant metastatic colorectal cancer: therapeutic strategies from the clinic and from the lab

Sartore-Bianchi, A., Loupakis, F., Argilés, G., Prager, G.W.

Journal:

Annals of Oncology

Year:

2016

Language:

english

File:

PDF, 620 KB

english, 2016

49

2184 A phase 2 study of mechanisms of acquired resistance to panitumumab (pmab) plus irinotecan (iri) for metastatic colorectal cancer (mCRC)

Siena, S., Sartore-Bianchi, A., Karthaus, M., Smith, D., Garcia-Carbonero, R., Van Cutsem, E., Guan, X., Boedigheimer, M., Sidhu, R., Jung, A.S., Oliner, K.S., Tabernero, J., Bardelli, A.

Journal:

European Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 72 KB

english, 2015

50

E08Prognostic significance of KRAS mutation rate in metastatic colorectal cancer patients

Vincenzi, B., Cremolini, C., Sartore-Bianchi, A., Russo, A., Mannavola, F., Perrone, G., Pantano, F., Loupakis, F., Rossini, D., Ongaro, E., Bonazzina, E., Zoccoli, A., De Maglio, G., Fontanini, G., F

Journal:

Annals of Oncology

Year:

2015

Language:

english

File:

PDF, 33 KB

english, 2015

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