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51

A chemoenzymic route to (-)-pyrenophorin

Ngooi, T. K., Scilimati, A., Guo, Zhi Wei, Sih, Charles J.

Journal:

Journal of Organic Chemistry

Year:

1989

Language:

english

File:

PDF, 583 KB

english, 1989

52

Kluyveromyces marxianus CBS 6556 growing cells as a new biocatalyst in the asymmetric reduction of substituted acetophenones

Vitale, Paola, D’Introno, Cinzia, Perna, Filippo Maria, Perrone, Maria Grazia, Scilimati, Antonio

Journal:

Tetrahedron: Asymmetry

Year:

2013

Language:

english

File:

PDF, 396 KB

english, 2013

53

β 3 -Adrenoceptor ligand development history through patent review

Perrone, Maria Grazia, Scilimati, Antonio

Journal:

Expert Opinion on Therapeutic Patents

Year:

2011

Language:

english

File:

PDF, 1.64 MB

english, 2011

54

Synthesis, Pharmacological Characterization, and Docking Analysis of a Novel Family of Diarylisoxazoles as Highly Selective Cyclooxygenase-1 (COX-1) Inhibitors

Vitale, Paola, Tacconelli, Stefania, Perrone, Maria Grazia, Malerba, Paola, Simone, Laura, Scilimati, Antonio, Lavecchia, Antonio, Dovizio, Melania, Marcantoni, Emanuela, Bruno, Annalisa, Patrignani,

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 2.00 MB

english, 2013

55

Optically Active Mexiletine Analogues as Stereoselective Blockers of Voltage-Gated Na + Channels

Franchini, Carlo, Carocci, Alessia, Catalano, Alessia, Cavalluzzi, Maria M., Corbo, Filomena, Lentini, Giovanni, Scilimati, Antonio, Tortorella, Paolo, Camerino, Diana Conte, Luca, Annamaria De

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 162 KB

english, 2003

56

Myogenic effect of SP-1f and SP-1h two novel β3-adrenoceptor (β3-AR) agonists in human colonic circular smooth muscle

Maselli, Maria Antonietta, Trisolini, Piero, Ignazzi, Antonia, Notarnicola, Maria, Lorusso, Dionigi, Pezzolla, Francesco, Iacobazzi, Dominga, Scilimati, Antonio, Perrone, Maria Grazia

Journal:

European Journal of Pharmacology

Year:

2014

Language:

english

File:

PDF, 689 KB

english, 2014

57

Selective COX-1 inhibition as a target of theranostic novel diarylisoxazoles

Vitale, Paola, Perrone, Maria Grazia, Malerba, Paola, Lavecchia, Antonio, Scilimati, Antonio

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.47 MB

english, 2014

58

Optically Active Mexiletine Analogues as Stereoselective Blockers of Voltage-Gated Na + Channels.

Franchini, Carlo, Carocci, Alessia, Catalano, Alessia, Cavalluzzi, Maria M., Corbo, Filomena, Lentini, Giovanni, Scilimati, Antonio, Tortorella, Paolo, Camerino, Diana Conte, De Luca, Annamaria

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 41 KB

english, 2005

59

Synthesis of New 2,6-Prolylxylidide Analogues of Tocainide as Stereoselective Blockers of Voltage-Gated Na + Channels with Increased Potency and Improved Use-Dependent Activity

Franchini, Carlo, Corbo, Filomena, Lentini, Giovanni, Bruno, Gemma, Scilimati, Antonio, Tortorella, Vincenzo, Conte Camerino, Diana, De Luca, Annamaria

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 96 KB

english, 2000

60

Upregulation of β3-Adrenergic Receptor mRNA in Human Colon Cancer: A Preliminary Study

Perrone, Maria Grazia, Notarnicola, Maria, Caruso, Maria Gabriella, Tutino, Valeria, Scilimati, Antonio

Journal:

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

61

General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model

Perrone, Maria Grazia, Vitale, Paola, Panella, Andrea, Fortuna, Cosimo G., Scilimati, Antonio

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 2.41 MB

english, 2015

62

The Reaction of Arylaldehydes with Hexamethylphosphorous Triamide and the Use of the Resulting Products for the Synthesis of Enamines and Deoxybenzoins

Babudri, Francesco, Fiandanese, Vito, Musio, Roberta, Naso, Francesco, Sciavovelli, Oronzo, Scilimati, Antonio

Journal:

Year:

1991

File:

PDF, 317 KB

1991

63

A Novel Synthesis of N-Unsubstituted β-Enamino Thioesters from 3-Arylisoxazoles and 3-Aryl-5-phenylthio-2-isoxazolines

Vitale, Paola, Di Nunno, Leonardo, Scilimati, Antonio

Journal:

Year:

2010

Language:

english

File:

PDF, 162 KB

english, 2010

64

Functional 3-Arylisoxazoles and 3-Aryl-2-isoxazolines from Reaction of Aryl Nitrile Oxides and Enolates: Synthesis and Reactivity

Vitale, Paola, Scilimati, Antonio

Journal:

Year:

2013

Language:

english

File:

PDF, 260 KB

english, 2013

65

3-Aryl-5-vinyl-2-isoxazolines and 3-Aryl-5-vinylisoxazoles from Aryl Nitrile Oxides and Methyl Vinyl Ketone Lithium Enolate: Reaction Limits and Synthetic Utility Exploitation

Salomone, Antonio, Scilimati, Antonio, Vitale, Paola

Journal:

Year:

2014

Language:

english

File:

PDF, 237 KB

english, 2014

66

A Highly Efficient Kinetic Resolution of ω-Trimethylsilyl Polyunsaturated Secondary Alcohols by Lipase-Catalyzed Transesterification

Fiandanese, Vito, Hassan, Omar, Naso, Francesco, Scilimati, Antonio

Journal:

Year:

1993

File:

PDF, 177 KB

1993

67

Selective COX-1 Inhibition: A Therapeutic Target to be Reconsidered

G. Perrone, M., Scilimati, A., Simone, L., Vitale, P.

Journal:

Current Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.50 MB

english, 2010

68

A Chemoenzymatic Route to Both Enantiomers of Betaxolol

Di Bono, Giuseppe, Scilimati, Antonio

Journal:

Year:

1995

File:

PDF, 370 KB

1995

69

Cheap and environmentally sustainable stereoselective arylketones reduction by Lactobacillus reuteri whole cells

Perna, F.M., Ricci, M.A., Scilimati, A., Mena, M.C., Pisano, I., Palmieri, L., Agrimi, G., Vitale, P.

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2016

Language:

english

File:

PDF, 916 KB

english, 2016

70

Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs)

Perrone, Maria Grazia, Vitale, Paola, Panella, Andrea, Ferorelli, Savina, Contino, Marialessandra, Lavecchia, Antonio, Scilimati, Antonio

Journal:

Year:

2016

Language:

english

File:

PDF, 2.59 MB

english, 2016

71

ChemInform Abstract: Selective Reduction of Aldehydes to the Corresponding Primary Alcohols by Lithium Enolate of Acetaldehyde.

DI NUNNO, L., SCILIMATI, A.

Journal:

Year:

1988

File:

PDF, 105 KB

1988

72

ChemInform Abstract: Kluyveromyces marxianus CBS 6556 Growing Cells as a New Biocatalyst in the Asymmetric Reduction of Substituted Acetophenones.

Vitale, Paola, D'Introno, Cinzia, Perna, Filippo Maria, Perrone, Maria Grazia, Scilimati, Antonio

Journal:

Year:

2013

File:

PDF, 29 KB

2013

73

ChemInform Abstract: Biocatalytic Resolution of (.+-.)-Hydroxyalkanoic Esters. A Strategy for Enhancing the Enantiomeric Specificity of Lipase-Catalyzed Ester Hydrolysis.

SCILIMATI, A., NGOOI, T. K., SIH, C. J.

Journal:

Year:

1989

File:

PDF, 76 KB

1989

74

ChemInform Abstract: Macrocyclic Lactones via Biocatalysis in Non-Aqueous Media.

GUO, Z., NGOOI, T. K., SCILIMATI, A., FUELLING, G., SIH, C. J.

Journal:

Year:

1989

File:

PDF, 90 KB

1989

75

COX-1 Inhibitors: Beyond Structure Toward Therapy

Vitale, Paola, Panella, Andrea, Scilimati, Antonio, Perrone, Maria Grazia

Journal:

Medicinal Research Reviews

Year:

2016

Language:

english

File:

PDF, 2.23 MB

english, 2016

76

ChemInform Abstract: Functional 3-Arylisoxazoles and 3-Aryl-2-isoxazolines from Reaction of Aryl Nitrile Oxides and Enolates: Synthesis and Reactivity

Vitale, Paola, Scilimati, Antonio

Journal:

Year:

2014

File:

PDF, 18 KB

2014

77

ChemInform Abstract: Five-Membered Ring Heterocycles by Reacting Enolates with Dipoles.

Vitale, Paola, Scilimati, Antonio

Journal:

Year:

2014

File:

PDF, 17 KB

2014

78

Asymmetric Chemoenzymatic Synthesis of 1,3-Diols and 2,4-Disubstituted Aryloxetanes by Using Whole Cell Biocatalysts

Vitale, Paola, Perna, Filippo Maria, Agrimi, Gennaro, Scilimati, Antonio, Salomone, Antonio, Cardellicchio, Cosimo, Capriati, Vito

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 724 KB

english, 2016

79

A novel injectable formulation of 6-fluoro- l -DOPA imaging agent for diagnosis of neuroendocrine tumors and Parkinson’s disease

Trapani, Adriana, Tricarico, Domenico, Mele, Antonietta, Maqoud, Fatima, Mandracchia, Delia, Vitale, Paola, Capriati, Vito, Trapani, Giuseppe, Dimiccoli, Vincenzo, Tolomeo, Anna, Scilimati, Antonio

Journal:

International Journal of Pharmaceutics

Year:

2017

Language:

english

File:

PDF, 1.35 MB

english, 2017

80

SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism

Menga, Alessio, Palmieri, Erika M., Cianciulli, Antonia, Infantino, Vittoria, Mazzone, Massimiliano, Scilimati, Antonio, Palmieri, Ferdinando, Castegna, Alessandra, Iacobazzi, Vito

Journal:

Year:

2017

Language:

english

File:

PDF, 854 KB

english, 2017

81

Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6)

Cingolani, Gino, Panella, Andrea, Perrone, Maria Grazia, Vitale, Paola, Di Mauro, Giuseppe, Fortuna, Cosimo G., Armen, Roger S., Ferorelli, Savina, Smith, William L., Scilimati, Antonio

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 767 KB

english, 2017

82

[ 18 F]F-DOPA synthesis by poly(dimethylsiloxane)-based platforms: thermal aging protocol to reduce chemicals-induced damage

Cesaria, Maura, Arima, Valentina, Rella, Simona, Malitesta, Cosimino, Martucci, Maria Concetta, Manera, Maria Grazia, Tolomeo, Anna, Scilimati, Antonio, Rella, Roberto

Journal:

Sensors and Actuators B: Chemical

Year:

2018

Language:

english

File:

PDF, 3.05 MB

english, 2018

83

Industrial Internet of things at work: a case study analysis in robotic-aided environmental monitoring

Scilimati, Vito, Petitti, Antonio, Boccadoro, Pietro, Colella, Roberto, Di Paola, Donato, Milella, Annalisa, Alfredo Grieco, Luigi

Journal:

IET Wireless Sensor Systems

Year:

2017

Language:

english

File:

PDF, 2.41 MB

english, 2017

84

Bisphosphonates Regulate Osteoblasts/Osteoclasts Proliferation Inducing Bone Mineralization

Scala, Rosa, Angelelli, Mariacristina, Maqoud, Fatima, Scilimati, Antonio, Tricarico, Domenico

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 64 KB

english, 2018

85

Stereoselective Chemoenzymatic Synthesis of Optically Active Aryl-Substituted Oxygen-Containing Heterocycles

Vitale, Paola, Digeo, Antonia, Perna, Filippo, Agrimi, Gennaro, Salomone, Antonio, Scilimati, Antonio, Cardellicchio, Cosimo, Capriati, Vito

Journal:

Year:

2017

Language:

english

File:

PDF, 1.29 MB

english, 2017

86

Five-membered Ring Heterocycles by Reacting Enolates with Dipoles

Vitale, Paola, Scilimati, Antonio

Journal:

Current Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 364 KB

english, 2013

87

Exploring prospects of β3-adrenoceptor agonists and inverse agonists for colon mobility control

Perrone, Maria Grazia, Contino, Marialessandra, Scilimati, Antonio

Journal:

Drugs and Therapy Studies

Year:

2013

Language:

english

File:

PDF, 646 KB

english, 2013

88

Microfluidic pervaporation of ethanol from radiopharmaceutical formulations

Zizzari, A., Bianco, M., Perrone, E., Manera, M.G., Cellamare, S., Ferorelli, S., Purgatorio, R., Scilimati, A., Tolomeo, A., Dimiccoli, V., Rella, R., Arima, V.

Journal:

Chemical Engineering and Processing: Process Intensification

Year:

2019

Language:

english

File:

PDF, 798 KB

english, 2019

89

Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection

Scilimati, Antonio, Ferorelli, Savina, Iaselli, Maria Clara, Miciaccia, Morena, Pati, Maria Laura, Fortuna, Cosimo G., Aleem, Ansari M., Marnett, Lawrence J., Perrone, Maria Grazia

Journal:

European Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.65 MB

english, 2019

90

(S)-Ethyl 2-(tert-butoxycarbonylamino)-3-(2-iodo-4,5-methylenedioxyphenyl)propanoate

Lentini, Giovanni, Cavalluzzi, Maria, Degennaro, Leonardo, Fracchiolla, Giuseppe, Perna, Filippo, Scilimati, Antonio

Journal:

Year:

2019

File:

PDF, 764 KB

2019

91

Intelligent Microarray Data Analysis through Non-negative Matrix Factorization to Study Human Multiple Myeloma Cell Lines

Casalino, Gabriella, Coluccia, Mauro, Pati, Maria L., Pannunzio, Alessandra, Vacca, Angelo, Scilimati, Antonio, Perrone, Maria G.

Journal:

Applied Sciences

Year:

2019

Language:

english

File:

PDF, 6.35 MB

english, 2019

92

Inhibition of cyclooxygenase-1 does not reduce mortality in post-ischemic stroke rats

Rostevanov, Ira S., Boyko, Matthew, Ferorelli, Savina, Scilimati, Antonio, Perrone, Maria Grazia, Kaplanski, Jacob, Zlotnik, Alexander, Azab, Abed N.

Journal:

Neuroscience Letters

Year:

2020

File:

PDF, 2.44 MB

2020

93

Cyclooxygenase Inhibition Safety and Efficacy in Inflammation-Based Psychiatric Disorders

Perrone, Maria Grazia, Centonze, Antonella, Miciaccia, Morena, Ferorelli, Savina, Scilimati, Antonio

Journal:

Year:

2020

File:

PDF, 3.43 MB

2020