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51

The crystal structure of endoglucanase CelA, a family 8 glycosyl hydrolase from Clostridium thermocellum

Pedro M Alzari, Hélè ne Souchon, Roberto Dominguez

Journal:

Year:

1996

Language:

english

File:

PDF, 1.56 MB

english, 1996

52

ANALYSIS OF HUMAN IL-2/IL-2 RECEPTOR β CHAIN INTERACTIONS: MONOCLONAL ANTIBODY H2-8 AND NEW IL-2 MUTANTS DEFINE THE CRITICAL ROLE OF α HELIX-A OF IL-2

Ralph Eckenberg, Di Xu, Jean-Louis Moreau, Marc Bossus, Jean-Claude Mazié, André Tartar, Xin Yuan Liu, Pedro M. Alzari, Jacques Bertoglio, Jacques Thèze

Journal:

Year:

1997

Language:

english

File:

PDF, 371 KB

english, 1997

53

Crystallization and Preliminary Crystallographic Analysis of a Tetrameric Isolectin from Vicia villosa, Specific for the Tn Antigen

Jean-Luc Eiselé, Diana Tello, Eduardo Osinaga, Alberto Roseto, Pedro M. Alzari

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 134 KB

1993

54

Crystallization and Preliminary Diffraction Analysis of the Catalytic Domain of Xylanase Z from Clostridium thermocellum

Hélène Souchon, Silvia Spinelli, Pierre Béguin, Pedro M. Alzari

Journal:

Journal of Molecular Biology

Year:

1994

File:

PDF, 158 KB

1994

55

The Crystal Structure of a Family 5 Endoglucanase Mutant in Complexed and Uncomplexed Forms Reveals an Induced Fit Activation Mechanism

Roberto Domı́nguez, Hélène Souchon, Marie-Bernard Lascombe, Pedro M. Alzari

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 591 KB

english, 1996

56

The crystal structure of a type I cohesin domain at 1.7 Å resolution

Gisele A Tavares, Pierre Béguin, Pedro M Alzari

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 1022 KB

english, 1997

57

Structure of catalase-A from Saccharomyces cerevisiae

Maria J. Maté, Marcel Zamocky, Leena M. Nykyri, Christian Herzog, Pedro M. Alzari, Christian Betzel, Franz Koller, Ignacio Fita

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 2.14 MB

english, 1999

58

Atomic (0.94 Å) resolution structure of an inverting glycosidase in complex with substrate

Diego M.A Guérin, Marie-Bernard Lascombe, Marcelo Costabel, Hélène Souchon, Victor Lamzin, Pierre Béguin, Pedro M Alzari

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 723 KB

english, 2002

59

The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria

Annemarie Wehenkel, Pablo Fernandez, Marco Bellinzoni, Vincent Catherinot, Nathalie Barilone, Gilles Labesse, Mary Jackson, Pedro M. Alzari

Journal:

Year:

2006

Language:

english

File:

PDF, 295 KB

english, 2006

60

Sub-families of α/β Barrel Enzymes: A New Adenine Deaminase Family

Carin Ribard, Michel Rochet, Bernard Labedan, Bertrand Daignan-Fornier, Pedro Alzari, Claudio Scazzocchio, Nathalie Oestreicher

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.94 MB

english, 2003

61

A Sialidase Mutant Displaying trans-Sialidase Activity

Gastón Paris, Laura Ratier, María Fernanda Amaya, Tong Nguyen, Pedro M. Alzari, Alberto Carlos C. Frasch

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 577 KB

english, 2005

62

Structural and Binding Studies of the Three-metal Center in Two Mycobacterial PPM Ser/Thr Protein Phosphatases

Annemarie Wehenkel, Marco Bellinzoni, Francis Schaeffer, Andrea Villarino, Pedro M. Alzari

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 909 KB

english, 2007

63

Artificial Binding Proteins (Affitins) as Probes for Conformational Changes in Secretin PulD

Martin Krehenbrink, Mohamed Chami, Ingrid Guilvout, Pedro M. Alzari, Frédéric Pécorari, Anthony P. Pugsley

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 743 KB

english, 2008

64

Functional in vitro assembly of the integral membrane bacterial thermosensor DesK

Mariana Martín, Daniela Albanesi, Pedro M. Alzari, Diego de Mendoza

Journal:

Protein Expression and Purification

Year:

2009

Language:

english

File:

PDF, 519 KB

english, 2009

65

Rising standards for tuberculosis drug development

Tanjore S. Balganesh, Pedro M. Alzari, Stewart T. Cole

Journal:

Trends in Pharmacological Sciences

Year:

2008

Language:

english

File:

PDF, 143 KB

english, 2008

66

Analysis of the fine specificity of Tn-binding proteins using synthetic glycopeptide epitopes and a biosensor based on surface plasmon resonance spectroscopy

Eduardo Osinaga, Sylvie Bay, Diana Tello, Alvaro Babino, Otto Pritsch, Karine Assemat, Daniele Cantacuzene, Hiroshi Nakada, Pedro Alzari

Journal:

Year:

2000

Language:

english

File:

PDF, 105 KB

english, 2000

67

The crystal structure of a plant lectin in complex with the Tn antigen

Alvaro Babino, Diana Tello, Adriana Rojas, Sylvie Bay, Eduardo Osinaga, Pedro M Alzari

Journal:

Year:

2003

Language:

english

File:

PDF, 472 KB

english, 2003

68

Amino acid sequence and three-dimensional structure of the Tn-specific isolectin B4 from Vicia villosa

Eduardo Osinaga, Diana Tello, Carlos Batthyany, Mario Bianchet, Gisele Tavares, Rosario Durán, Carlos Cerveñansky, Luc Camoin, Alberto Roseto, Pedro M Alzari

Journal:

Year:

1997

Language:

english

File:

PDF, 867 KB

english, 1997

69

The MBP fusion protein restores the activity of the first phosphatase domain of CD45

Hans K Lorenzo, Donna Farber, Valérie Germain, Oreste Acuto, Pedro M Alzari

Journal:

Year:

1997

Language:

english

File:

PDF, 989 KB

english, 1997

70

The Crystal Structure and Catalytic Mechanism of Cellobiohydrolase CelS, the Major Enzymatic Component of the Clostridium thermocellum Cellulosome

Beatriz G. Guimarães, Hélène Souchon, Betsy L. Lytle, J.H. David Wu, Pedro M. Alzari

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 1.60 MB

english, 2002

71

The High Resolution Structures of Free and Inhibitor-bound Trypanosoma rangeli Sialidase and its Comparison with T. cruzi Trans-sialidase

Maria Fernanda Amaya, Alejandro Buschiazzo, Tong Nguyen, Pedro M. Alzari

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.64 MB

english, 2003

72

Multiple crystal forms of endoglucanase CelD: Signal peptide residues modulate lattice formation

Véronique Chitarra, Hélène Souchon, Silvia Spinelli, Michel Juy, Pierre Béguine, Pedro M. Alzari

Journal:

Journal of Molecular Biology

Year:

1995

Language:

english

File:

PDF, 3.43 MB

english, 1995

73

The Crystal Structure and Mode of Action of Trans-Sialidase, a Key Enzyme in Trypanosoma cruzi Pathogenesis

Alejandro Buschiazzo, Marı́a F. Amaya, Marı́a L. Cremona, Alberto C. Frasch, Pedro M. Alzari

Journal:

Year:

2002

Language:

english

File:

PDF, 539 KB

english, 2002

74

Substrate-Selective Inhibition of Protein Kinase PDK1 by Small Compounds that Bind to the PIF-Pocket Allosteric Docking Site

Katrien Busschots, Laura A. Lopez-Garcia, Carmen Lammi, Adriana Stroba, Stefan Zeuzem, Albrecht Piiper, Pedro M. Alzari, Sonja Neimanis, Jose M. Arencibia, Matthias Engel, Jörg O. Schulze, Ricardo M.

Journal:

Chemistry & Biology

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

75

Crystallization and preliminary X-ray diffraction study of an endoglucanase from Clostridium thermocellum

Gwennaël Joliff, Pierre Béguin, Jacqueline Millet, Jean-Paul Aubert, Pedro Alzari, Michel Juy, Roberto J. Poljak

Journal:

Journal of Molecular Biology

Year:

1986

Language:

english

File:

PDF, 145 KB

english, 1986

76

A Novel Role of Malonyl-ACP in Lipid Homeostasis ,

Martinez, Mariano A., Zaballa, María-Eugenia, Schaeffer, Francis, Bellinzoni, Marco, Albanesi, Daniela, Schujman, Gustavo E., Vila, Alejandro J., Alzari, Pedro M., de Mendoza, Diego

Journal:

Year:

2010

Language:

english

File:

PDF, 2.44 MB

english, 2010

77

Inhibition of Mycobacterium tuberculosis PknG by non-catalytic rubredoxin domain specific modification: reaction of an electrophilic nitro-fatty acid with the Fe–S center

Gil, Magdalena, Graña, Martín, Schopfer, Francisco J., Wagner, Tristan, Denicola, Ana, Freeman, Bruce A., Alzari, Pedro M., Batthyány, Carlos, Durán, Rosario

Journal:

Free Radical Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 6.75 MB

english, 2013

78

A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase)

Wagner, Tristan, Barilone, Nathalie, Alzari, Pedro M., Bellinzoni, Marco

Journal:

Biochemical Journal

Year:

2014

Language:

english

File:

PDF, 1.93 MB

english, 2014

79

Preliminary crystallographic study of a complex between an heteroclitic anti-hen egg-white lysozyme antibody and the heterologous antigen pheasant egg-white lysozyme

Guillon, Véronique, Alzari, Pedro M., Poljak, Roberto J.

Journal:

Journal of Molecular Biology

Year:

1987

Language:

english

File:

PDF, 191 KB

english, 1987

80

Nitroalkene Oleic Acid Irreversibly Inhibited Mycobacterium Tuberculosis PknG by Electrophilic Attack to Cysteins in the Non-Catalytic Rubredoxin Domain

Gil, Magdalena, Denicola, Ana, Batthyany, Carlos, Schopfer, Francisco, Freeman, Bruce, Alzari, Pedro, Durán, Rosario

Journal:

Free Radical Biology and Medicine

Year:

2012

Language:

english

File:

PDF, 220 KB

english, 2012

81

Preliminary crystallographic study of the Fab fragment of a monoclonal antibody directed against a cobra cardiotoxin

Guillon, Véronique, Alzari, Pedro M., Grognet, Jean-Marc

Journal:

Journal of Molecular Biology

Year:

1986

Language:

english

File:

PDF, 155 KB

english, 1986

82

Plasmodium falciparum Subtilisin-Like Protease 2, a Merozoite Candidate for the Merozoite Surface Protein 1-42 Maturase

Jean-Christophe Barale, Thierry Blisnick, Hisashi Fujioka, Pedro M. Alzari, Masamishi Aikawa, Catherine Braun-Breton and Gordon Langsley

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.40 MB

english, 1999

83

Mapping by Site-Directed Mutagenesis of the Region Responsible for Cohesin−Dockerin Interaction on the Surface of the Seventh Cohesin Domain of Clostridium thermocellum CipA †

Miras, Isabelle, Schaeffer, Francis, Béguin, Pierre, Alzari, Pedro M.

Journal:

Year:

2002

Language:

english

File:

PDF, 180 KB

english, 2002

84

GarA is an essential regulator of metabolism in Mycobacterium tuberculosis

Ventura, Marcello, Rieck, Barbara, Boldrin, Francesca, Degiacomi, Giulia, Bellinzoni, Marco, Barilone, Nathalie, Alzaidi, Faisal, Alzari, Pedro M., Manganelli, Riccardo, O'Hare, Helen M.

Journal:

Molecular Microbiology

Year:

2013

Language:

english

File:

PDF, 3.25 MB

english, 2013

85

Kinetic and Mechanistic Analysis of Trypanosoma cruzi Trans-Sialidase Reveals a Classical Ping-Pong Mechanism with Acid/Base Catalysis †

Damager, Iben, Buchini, Sabrina, Amaya, Maria F., Buschiazzo, Alejandro, Alzari, Pedro, Frasch, Alberto C., Watts, Andrew, Withers, Stephen G.

Journal:

Year:

2008

Language:

english

File:

PDF, 113 KB

english, 2008

86

Duplicated Dockerin Subdomains of Clostridium thermocellum Endoglucanase CelD Bind to a Cohesin Domain of the Scaffolding Protein CipA with Distinct Thermodynamic Parameters and a Negative Cooperativity †

Schaeffer, Francis, Matuschek, Markus, Guglielmi, Gérard, Miras, Isabelle, Alzari, Pedro M., Béguin, Pierre

Journal:

Year:

2002

Language:

english

File:

PDF, 167 KB

english, 2002

87

Trypanosoma c ruzi Trans-sialidase Operates through a Covalent Sialyl−Enzyme Intermediate: Tyrosine Is the Catalytic Nucleophile

Watts, Andrew G., Damager, Iben, Amaya, Maria L., Buschiazzo, Alejandro, Alzari, Pedro, Frasch, Alberto C., Withers, Stephen G.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 46 KB

english, 2003

88

Molecular Recognition of Artificial Single-Electron Acceptor Cosubstrates by Glucose Oxidase?

Alzari, Pedro, Anicet, Nathalie, Bourdillon, Christian, Moiroux, Jacques, Savéant, Jean-Michel

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 121 KB

english, 1996

89

Structural Features Involved in the Formation of a Complex between the Monomeric or the Dimeric Form of the Rev-erbβ DNA-Binding Domain and Its DNA Reactive Sites †,‡

Terenzi, Hernan, Alzari, Pedro M., Zakin, Mario M.

Journal:

Year:

1998

Language:

english

File:

PDF, 186 KB

english, 1998

90

Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c

Bellinzoni, Marco, Haouz, Ahmed, Miras, Isabelle, Magnet, Sophie, André-Leroux, Gwénaëlle, Mukherjee, Raju, Shepard, William, Cole, Stewart T., Alzari, Pedro M.

Journal:

Journal of Structural Biology

Year:

2014

Language:

english

File:

PDF, 1.71 MB

english, 2014

91

Stereoselective synthesis and X-ray crystallographic analysis of mixed 6,6-dihalo penicillanates

Belinzoni, Diego U., Mascaretti, Oreste A., Alzari, Pedro M., Punte, Graciela, Faerman, Carlos, Podjarny, Alberto

Journal:

Canadian Journal of Chemistry

Year:

1985

Language:

english

File:

PDF, 346 KB

english, 1985

92

Three-Dimensional Structure of Two Crystal Forms of FabR19.9 from a Monoclonal Anti-Arsonate Antibody

Marie-Bernard Lascombe, Pedro M. Alzari, Roberto J. Poljak and Alfred Nisonoff

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1001 KB

english, 1992

93

Production and Functional Characterization of Two Mouse/Human Chimeric Antibodies With Specificity for the Tumor-Associated Tn-Antigen

Oppezzo, Pablo, Osinaga, Eduardo, Tello, Diana, Bay, Sylvie, Cantacuzene, Daniele, Irigoín, Florencia, Ferreira, Ana, Roseto, Alberto, Cayota, Alfonso, Alzari, Pedro, Pritsch, Otto

Journal:

Year:

2000

Language:

english

File:

PDF, 566 KB

english, 2000

94

Molecular Cloning of a Monoclonal Anti-Tumor Antibody Specific for the Tn Antigen and Expression of an Active Single-Chain Fv Fragment

BABINO, ALVARO, PRITSCH, OTTO, OPPEZZO, PABLO, Du PASQUIER, RENAUD, ROSETO, ALBERTO, OSINAGA, EDUARDO, ALZARI, PEDRO M.

Journal:

Year:

1997

Language:

english

File:

PDF, 2.97 MB

english, 1997

95

The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation

Wagner, Tristan, Alexandre, Matthieu, Duran, Rosario, Barilone, Nathalie, Wehenkel, Annemarie, Alzari, Pedro M., Bellinzoni, Marco

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

96

Structure and Mechanism of the Alkyl Hydroperoxidase AhpC, a Key Element of the Mycobacterium tuberculosis Defense System against Oxidative Stress

Guimarães, Beatriz G., Souchon, Hélène, Honoré, Nadine, Saint-Joanis, Brigitte, Brosch, Roland, Shepard, William, Cole, Stewart T., Alzari, Pedro M.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 1.06 MB

english, 2005

97

Induction of Protective Immunity by Synthetic Vibrio cholerae Hexasaccharide Derived from V. cholerae O1 Ogawa Lipopolysaccharide Bound to a Protein Carrier

Chernyak, Anatoly, Kondo, Seiichi, Wade, Terri K., Meeks, Michael D., Alzari, Pedro M., Fournier, Jean‐Michel, Taylor, Ronald K., Kováč, Pavol, Wade, William F.

Journal:

The Journal of Infectious Diseases

Year:

2002

Language:

english

File:

PDF, 504 KB

english, 2002

98

Three-Dimensional Structure of a Heteroclitic Antigen-Antibody Cross- Reaction Complex

Veronique Chitarra, Pedro M. Alzari, Graham A. Bentley, T. Narayana Bhat, Jean-Luc Eisele, Anne Houdusse, Julien Lescar, Helene Souchon and Roberto J. Poljak

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.16 MB

english, 1993

99

Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation

Mechaly, Ariel E., Sassoon, Nathalie, Betton, Jean-Michel, Alzari, Pedro M., Hughson, Frederick

Journal:

Year:

2014

Language:

english

File:

PDF, 1.73 MB

english, 2014

100

Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus aureus

Albanesi, Daniela, Reh, Georgina, Guerin, Marcelo E., Schaeffer, Francis, Debarbouille, Michel, Buschiazzo, Alejandro, Schujman, Gustavo E., de Mendoza, Diego, Alzari, Pedro M., Saper, Mark A.

Journal:

Year:

2013

Language:

english

File:

PDF, 704 KB

english, 2013

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