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51

The GroEL/GroES cis cavity as a passive anti-aggregation device

Arthur L. Horwich, Adrian C. Apetri, Wayne A. Fenton

Journal:

Year:

2009

Language:

english

File:

PDF, 414 KB

english, 2009

52

ATP-triggered ADP release from the asymmetric chaperonin GroEL/GroES/ADP7 is not the rate-limiting step of the GroEL/GroES reaction cycle

Navneet K. Tyagi, Wayne A. Fenton, Arthur L. Horwich

Journal:

Year:

2010

Language:

english

File:

PDF, 314 KB

english, 2010

53

Double mutant MBP refolds at same rate in free solution as inside the GroEL/GroES chaperonin chamber when aggregation in free solution is prevented

Navneet K. Tyagi, Wayne A. Fenton, Ashok A. Deniz, Arthur L. Horwich

Journal:

Year:

2011

Language:

english

File:

PDF, 409 KB

english, 2011

54

Multiple States of a Nucleotide-Bound Group 2 Chaperonin

Daniel K. Clare, Scott Stagg, Joel Quispe, George W. Farr, Arthur L. Horwich, Helen R. Saibil

Journal:

Year:

2008

Language:

english

File:

PDF, 1.09 MB

english, 2008

55

Mechanisms of protein folding

Viara Grantcharova, Eric J Alm, David Baker, Arthur L Horwich

Journal:

Current Opinion in Structural Biology

Year:

2001

Language:

english

File:

PDF, 367 KB

english, 2001

56

Sorting pathways of mitochondrial inner membrane proteins

Kerstin MAHLKE, Nikolaus PFANNER, Jörg MARTIN, Arthur L. HORWICH, Franz-Ulrich HARTL, Walter NEUPERT

Journal:

Year:

1990

Language:

english

File:

PDF, 634 KB

english, 1990

57

Chaperoned Protein Disaggregation—The ClpB Ring Uses Its Central Channel

Arthur L. Horwich

Journal:

Year:

2004

Language:

english

File:

PDF, 68 KB

english, 2004

58

Loops in the Central Channel of ClpA Chaperone Mediate Protein Binding, Unfolding, and Translocation

Jörg Hinnerwisch, Wayne A. Fenton, Krystyna J. Furtak, George W. Farr, Arthur L. Horwich

Journal:

Year:

2005

Language:

english

File:

PDF, 1.50 MB

english, 2005

59

Molecular Chaperones and Protein Quality Control

Bernd Bukau, Jonathan Weissman, Arthur Horwich

Journal:

Year:

2006

Language:

english

File:

PDF, 949 KB

english, 2006

60

No evidence for a forced-unfolding mechanism during ATP/GroES binding to substrate-bound GroEL: no observable protection of metastable Rubisco intermediate or GroEL-bound Rubisco from tritium exchange

Eun Sun Park, Wayne A. Fenton, Arthur L. Horwich

Journal:

Year:

2005

Language:

english

File:

PDF, 97 KB

english, 2005

61

Exploring the Structural Dynamics of the E. coli Chaperonin GroEL Using Translation-libration-screw Crystallographic Refinement of Intermediate States

Charu Chaudhry, Arthur L. Horwich, Axel T. Brunger, Paul D. Adams

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 1.31 MB

english, 2004

62

Topologies of a Substrate Protein Bound to the Chaperonin GroEL

Nadav Elad, George W. Farr, Daniel K. Clare, Elena V. Orlova, Arthur L. Horwich, Helen R. Saibil

Journal:

Year:

2007

Language:

english

File:

PDF, 1.50 MB

english, 2007

63

Chaperonin-Mediated Folding in the Eukaryotic Cytosol Proceeds through Rounds of Release of Native and Nonnative Forms

George W Farr, Elizabeth C Scharl, Robert J Schumacher, Stacey Sondek, Arthur L Horwich

Journal:

Year:

1997

Language:

english

File:

PDF, 355 KB

english, 1997

64

GroEL-GroES Cycling: ATP and Nonnative Polypeptide Direct Alternation of Folding-Active Rings

Hays S. Rye, Alan M. Roseman, Shaoxia Chen, Krystyna Furtak, Wayne A. Fenton, Helen R. Saibil, Arthur L. Horwich

Journal:

Year:

1999

Language:

english

File:

PDF, 561 KB

english, 1999

65

Characterization of the Active Intermediate of a GroEL–GroES-Mediated Protein Folding Reaction

Jonathan S Weissman, Hays S Rye, Wayne A Fenton, Joseph M Beechem, Arthur L Horwich

Journal:

Year:

1996

Language:

english

File:

PDF, 134 KB

english, 1996

66

GroEL/GroES-Mediated Folding of a Protein Too Large to Be Encapsulated

Tapan K. Chaudhuri, George W. Farr, Wayne A. Fenton, Sabine Rospert, Arthur L. Horwich

Journal:

Year:

2001

Language:

english

File:

PDF, 302 KB

english, 2001

67

ATP-Bound States of GroEL Captured by Cryo-Electron Microscopy

Neil A. Ranson, George W. Farr, Alan M. Roseman, Brent Gowen, Wayne A. Fenton, Arthur L. Horwich, Helen R. Saibil

Journal:

Year:

2001

Language:

english

File:

PDF, 918 KB

english, 2001

68

ClpS, a Substrate Modulator of the ClpAP Machine

David A Dougan, Brian G Reid, Arthur L Horwich, Bernd Bukau

Journal:

Year:

2002

Language:

english

File:

PDF, 582 KB

english, 2002

69

Structure and Allostery of the Chaperonin GroEL

Saibil, Helen R., Fenton, Wayne A., Clare, Daniel K., Horwich, Arthur L.

Journal:

Journal of Molecular Biology

Year:

2013

Language:

english

File:

PDF, 3.01 MB

english, 2013

70

Multivalent Binding of Nonnative Substrate Proteins by the Chaperonin GroEL

George W Farr, Krystyna Furtak, Matthew B Rowland, Neil A Ranson, Helen R Saibil, Tomas Kirchhausen, Arthur L Horwich

Journal:

Year:

2000

Language:

english

File:

PDF, 451 KB

english, 2000

71

Allosteric signaling of ATP hydrolysis in GroEL–GroES complexes

Ranson, Neil A, Clare, Daniel K, Farr, George W, Houldershaw, David, Horwich, Arthur L, Saibil, Helen R

Journal:

Nature Structural and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 983 KB

english, 2006

72

Targeting of Nuclear-Encoded Proteins to the Mitochondrial Matrix: Implications for Human Genetic Defects

LEON E. ROSENBERG, WAYNE A. FENTON, ARTHUR L. HORWICH, FRANTISEK KALOUSEK, JAN P. KRAUS

Journal:

Annals of the New York Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 586 KB

english, 1986

73

Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space

Hans Koll, Bernard Guiard, Joachim Rassow, Joachim Ostermann, Arthur L. Horwich, Walter Neupert, Franz-Ulrich Hartl

Journal:

Year:

1992

Language:

english

File:

PDF, 2.59 MB

english, 1992

74

GroEL-mediated protein folding proceeds by multiple rounds of binding and release of nonnative forms

Jonathan S. Weissman, Yechezkel Kashi, Wayne A. Fenton, Arthur L. Horwich

Journal:

Year:

1994

Language:

english

File:

PDF, 1.49 MB

english, 1994

75

A father and son with cholestasis and peripheral pulmonic stenosis: A distinct form of intrahepatic cholestasis

Caroline A. Riely, Douglas R. LaBrecque, Cameron Ghent, Arthur Horwich, Gerald Klatskin

Journal:

The Journal of Pediatrics

Year:

1978

Language:

english

File:

PDF, 2.30 MB

english, 1978

76

Duplication/deficiency mapping of situs inversus viscerum (iv), a gene that determines left-right asymmetry in the mouse

McGrath, James, Horwich, Arthur L., Brueckner, Martina

Journal:

Year:

1992

Language:

english

File:

PDF, 1.30 MB

english, 1992

77

GroEL−GroES-Mediated Protein Folding

Horwich, Arthur L., Farr, George W., Fenton, Wayne A.

Journal:

Chemical Reviews

Year:

2006

Language:

english

File:

PDF, 1.26 MB

english, 2006

78

A biochemical screen for GroEL/GroES inhibitors

Johnson, Steven M., Sharif, Orzala, Mak, Puiying Annie, Wang, Hsiao-Ting, Engels, Ingo H., Brinker, Achim, Schultz, Peter G., Horwich, Arthur L., Chapman, Eli

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 756 KB

english, 2014

79

[Part 1: Biological Sciences] || Molecular Cloning of the cDNA Coding for Rat Ornithine Transcarbamoylase

Arthur L. Horwich, Jan P. Kraus, Kenneth Williams, Frantisek Kalousek, William Konigsberg and Leon E. Rosenberg

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 1.44 MB

english, 1983

80

Import and Processing of Human Ornithine Transcarbamoylase Precursor by Mitochondria from Saccharomyces cerevisiae

Ming Yuan Cheng, Robert A. Pollock, Joseph P. Hendrick and Arthur L. Horwich

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 950 KB

english, 1987

81

Linkage Mapping of a Mouse Gene, iv, that Controls Left-Right Asymmetry of the Heart and Viscera

Martina Brueckner, Peter D'Eustachio and Arthur L. Horwich

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 976 KB

english, 1989

82

Native-Like Structure of a Protein-Folding Intermediate Bound to the Chaperonin GroEL

Matthew S. Goldberg, Jing Zhang, Stacey Sondek, C. Robert Matthews, Robert O. Fox and Arthur L. Horwich

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.50 MB

english, 1997

83

Folding in vivo of a Newly Translated Yeast Cytosolic Enzyme is Mediated by the SSA Class of Cytosolic Yeast Hsp70 Proteins

Suwon Kim, Brenda Schilke, Elizabeth A. Craig and Arthur L. Horwich

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.64 MB

english, 1998

84

Molecular Chaperones || Protein Folding in the Cell: Functions of Two Families of Molecular Chaperone, hsp 60 and TF55-TCP1 [and Discussion]

Arthur L. Horwich, Keith R. Willison, N. J. Cowan, P. Viitanen, P. Micklethwaite, M.-J. Gething, H. Saibil, C. Georgopoulos, F.-U. Hartl, W. J. Welch and K. Willison

Journal:

Philosophical Transactions Biological Sciences

Year:

1993

Language:

english

File:

PDF, 2.12 MB

english, 1993

85

Protein Folding || Unliganded GroEL at 2.8 angstrom: Structure and Functional Implications

Paul B. Sigler and Arthur L. Horwich

Journal:

Philosophical Transactions Biological Sciences

Year:

1995

Language:

english

File:

PDF, 1.92 MB

english, 1995

86

Protein Folding Causes an Arrest of Preprotein Translocation into Mitochondria in Vivo

Ulla Wienhues, Karin Becker, Manfred Schleyer, Bernard Guiard, Maximilian Tropschug, Arthur L. Horwich, Nikolaus Pfanner and Walter Neupert

Journal:

The Journal of Cell Biology

Year:

1991

Language:

english

File:

PDF, 1.73 MB

english, 1991

87

Probing the Sequence of Conformationally Induced Polarity Changes in the Molecular Chaperonin GroEL with Fluorescence Spectroscopy

Kim, So Yeon, Semyonov, Alexander N., Twieg, Robert J., Horwich, Arthur L., Frydman, Judith, Moerner, W. E.

Journal:

Journal of Physical Chemistry B

Year:

2005

Language:

english

File:

PDF, 326 KB

english, 2005

88

Solution NMR Techniques for Large Molecular and Supramolecular Structures

Riek, Roland, Fiaux, Jocelyne, Bertelsen, Eric B., Horwich, Arthur L., Wüthrich, Kurt

Journal:

Journal of the American Chemical Society

Year:

2002

Language:

english

File:

PDF, 317 KB

english, 2002

89

Selective degeneration of a physiological subtype of spinal motor neuron in mice with SOD1-linked ALS

Hadzipasic, Muhamed, Tahvildari, Babak, Nagy, Maria, Bian, Minjuan, Horwich, Arthur L., McCormick, David A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

90

Archaeal-like chaperonins in bacteria

Stephen M. Techtmann, Frank T. Robb and Arthur L. Horwich

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.50 MB

english, 2010

91

Current Topics in Membranes and Transport, Vol. 24: Membrane Protein Biosynthesis and Turnoverby Philip A. Knauf; John S. Cook

Review by: Arthur L. Horwich

Journal:

American Scientist

Year:

1987

Language:

english

File:

PDF, 307 KB

english, 1987

92

Unfolded DapA forms aggregates when diluted into free solution, confounding comparison with folding by the GroEL/GroES chaperonin system

Ambrose, Andrew J., Fenton, Wayne, Mason, Damian J., Chapman, Eli, Horwich, Arthur L.

Journal:

Year:

2015

Language:

english

File:

PDF, 379 KB

english, 2015

93

Overwhelming Sepsis in the Adult Variant of Wiskott-Aldrich Syndrome

Horwich, Arthur L.

Journal:

Archives of Internal Medicine

Year:

1984

Language:

english

File:

PDF, 463 KB

english, 1984

94

Chaperonin-mediated protein folding: using a central cavity to kinetically assist polypeptide chain folding

Horwich, Arthur L., Fenton, Wayne A.

Journal:

Quarterly Reviews of Biophysics

Year:

2009

Language:

english

File:

PDF, 865 KB

english, 2009

95

Chaperonin-mediated protein folding: fate of substrate polypeptide

Fenton, Wayne A., Horwich, Arthur L.

Journal:

Quarterly Reviews of Biophysics

Year:

2003

Language:

english

File:

PDF, 364 KB

english, 2003

96

A cDNA clone for the precursor of rat mitochondrial ornithine transcarbamylase: comparison of rat and human leader sequences and conservation of catalytic sites

Kraus, Jan P., Hodges, Peter E., Williamson, Cynthia L., Horwich, Arthur L., Kalousek, Frantisek, Williams, Kenneth R., Rosenberg, Leon E.

Journal:

Nucleic Acids Research

Year:

1985

Language:

english

File:

PDF, 1.16 MB

english, 1985

97

Heat Shock Transcription Factor σ32 Co-opts the Signal Recognition Particle to Regulate Protein Homeostasis in E. coli

Lim, Bentley, Miyazaki, Ryoji, Neher, Saskia, Siegele, Deborah A., Ito, Koreaki, Walter, Peter, Akiyama, Yoshinori, Yura, Takashi, Gross, Carol A., Horwich, Arthur L.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.10 MB

english, 2013

98

An ALS-Linked Mutant SOD1 Produces a Locomotor Defect Associated with Aggregation and Synaptic Dysfunction When Expressed in Neurons of Caenorhabditis elegans

Wang, Jiou, Farr, George W., Hall, David H., Li, Fei, Furtak, Krystyna, Dreier, Lars, Horwich, Arthur L., Cox, Gregory A.

Journal:

Year:

2009

Language:

english

File:

PDF, 859 KB

english, 2009

99

Precarious Balance of Nitrogen Metabolism in Women with a Urea-Cycle Defect

Horwich, Arthur L., Fenton, Wayne A.

Journal:

Boston Medical and Surgical Journal

Year:

1990

File:

PDF, 594 KB

1990

100

A sequential mechanism for clathrin cage disassembly by 70-kDa heat-shock cognate protein (Hsc70) and auxilin

Alice Rothnie, Anthony R. Clarke, Petr Kuzmic, Angus Cameron, Corinne J. Smith and Arthur L. Horwich

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.30 MB

english, 2011