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1

CD44 is the principal cell surface receptor for hyaluronate

Alejandro Aruffo, Ivan Stamenkovic, Michael Melnick, Charles B. Underhill, Brian Seed

Journal:

Year:

1990

Language:

english

File:

PDF, 9.78 MB

english, 1990

2

The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and α2–6 sialyltransferase, CD75, on B cells

Ivan Stamenkovic, Dennis Sgroi, Alejandro Aruffo, Man Sun Sy, Terri Anderson

Journal:

Year:

1991

Language:

english

File:

PDF, 4.76 MB

english, 1991

3

Identification of Hyaluronic Acid Binding Sites in the Extracellular Domain of CD44

Robert J. Peach, Diane Hollenbaugh, Ivan Stamenkovic and Alejandro Aruffo

Journal:

The Journal of Cell Biology

Year:

1993

Language:

english

File:

PDF, 1.85 MB

english, 1993

4

Construction and analysis of a detailed three-dimensional model of the ligand binding domain of the human B cell receptor CD40

Jürgen Bajorath, Alejandro Aruffo

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1997

Language:

english

File:

PDF, 415 KB

english, 1997

5

CD44 is not an adhesive receptor for osteopontin

Laura L. Smith, Brad W. Greenfield, Alejandro Aruffo, Cecilia M. Giachelli

Journal:

Journal of Cellular Biochemistry

Year:

1999

Language:

english

File:

PDF, 111 KB

english, 1999

6

Diminished expression of CD40 ligand may contribute to the defective humoral immunity in patients with MHC class II deficiency

Shigeaki Nonoyama, Amos Etzioni, Hano Toru, Dennis P. Ruggerie, David Lewis, Shimon Pollack, Alejandro Aruffo, Jun-Ichi Yata, Hans D. Ochs

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 205 KB

english, 1998

7

Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway

Ignacio Melero, Nathan Bach, Karl Erik Hellström, Alejandro Aruffo, Robert S. Mittler, Lieping Chen

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 134 KB

english, 1998

8

Cell surface receptors and their ligands: In vitro analysis of CD6-CD166 interactions

Michael A. Bowen, Alejandro A. Aruffo, Jürgen Bajorath

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2000

Language:

english

File:

PDF, 460 KB

english, 2000

9

GMP-140 (P-selectin/CD62) binds to chronically stimulated but not resting CD4+ T lymphocytes and regulates their production of proinflammatory cytokines

Nitin K. Damle, Kerry Klussman, Mary T. Dietsch, Alejandro Aruffo, Nahid Mohagheghpour

Journal:

European Journal of Immunology

Year:

1992

Language:

english

File:

PDF, 536 KB

english, 1992

10

Studies on the interdependence of gp39 and B7 expression and function during antigen-specific immune responses

Meenakshi Roy, Alejandro Aruffo, Jeffrey Ledbetter, Peter Linsley, Marilyn Kehry, Randolph Noelle

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 937 KB

english, 1995

11

Specific binding of Fyn and phosphatidylinositol 3-kinase to the B cell surface glycoprotein CD19 through their src homology 2 domains

N. Jan Chalupny, Alejandro Aruffo, James M. Esselstyn, Po-Ying Chan, Jürgen Bajorath, James Blake, Lisa K. Gilliland, Jeffrey A. Ledbetter, Mark A. Tepper

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 922 KB

english, 1995

12

The murine homolog of human Ep-CAM, a homotypic adhesion molecule, is expressed by thymocytes and thymic epithelial cells

Andrew J. Nelson, Robert J. Dunn, Robert Peach, Alejandro Aruffo, Andrew G. Farr

Journal:

European Journal of Immunology

Year:

1996

Language:

english

File:

PDF, 897 KB

english, 1996

13

Characterization of mouse CD6 with novel monoclonal antibodies which enhance the allogeneic mixed leukocyte reaction

Gary C. Starling, Gena S. Whitney, Anthony W. Siadak, Maj-Britt C. Llewellyn, Michael A. Bowen, Andrew G. Farr, Alejandro A. Aruffo

Journal:

European Journal of Immunology

Year:

1996

Language:

english

File:

PDF, 1.05 MB

english, 1996

14

CD40 is functionally expressed on human keratinocytes

Ralf W. Denfeld, Diane Hollenbaugh, Alexandra Fehrenbach, Johannes M. Weiss, Achim von Leoprechting, Brigit Mai, Ursula Voith, Erwin Schöpf, Alejandro Aruffo, Jan C. Simon

Journal:

European Journal of Immunology

Year:

1996

Language:

english

File:

PDF, 711 KB

english, 1996

15

Characterization of mouse ALCAM (CD166): the CD6-binding domain is conserved in different homologs and mediates cross-species binding

Michael A. Bowen, Jürgen Bajorath, Maurizia D'egidio, Gena S. Whitney, Dawn Palmer, Jörg Kobarg, Gary C. Starling, Anthony W. Siadak, Alejandro Aruffo

Journal:

European Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 1.41 MB

english, 1997

16

Analysis of the tyrosine phosphorylation and calcium fluxing of human CD6 isoforms with different cytoplasmatic domains

Jörg Kobarg, Gena S. Whitney, Dawn Palmer, Alejandro Aruffo, Michael A. Bowen

Journal:

European Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 1.34 MB

english, 1997

17

CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation

Randolph J. Noelle, Jeffrey A. Ledbetter, Alejandro Aruffo

Journal:

Immunology Today

Year:

1992

Language:

english

File:

PDF, 338 KB

english, 1992

18

Recombinant globulins: novel research tools and possible pharmaceuticals

Diane Hollenbaugh, N.Jan Chalupny, Alejandro Aruffo

Journal:

Current Opinion in Immunology

Year:

1992

Language:

english

File:

PDF, 463 KB

english, 1992

19

CD4, CD8 and the role of CD45 in T-cell activation

Jeffrey A. Ledbetter, Julie P. Deans, Alejandro Aruffo, Laura S. Grosmaire, Steven B. Kanner, Joseph B. Bolen, Gary L. Schieven

Journal:

Current Opinion in Immunology

Year:

1993

Language:

english

File:

PDF, 1009 KB

english, 1993

20

Expression cloning systems

Alejandro Aruffo

Journal:

Current Opinion in Biotechnology

Year:

1991

Language:

english

File:

PDF, 583 KB

english, 1991

21

Current applications of COS cell based transient expression systems

Caroline P. Edwards, Alejandro Aruffo

Journal:

Current Opinion in Biotechnology

Year:

1993

Language:

english

File:

PDF, 612 KB

english, 1993

22

Syntheses of iron(III) aroyl hydrazones containing pyridoxal and salicylaldehyde. The crystal and molecular structure of two iron(III)-pyridoxal isonicotinoyl hydrazone complexes

Terrance B. Murphy, Norman J. Rose, Verner Schomaker, Alejandro Aruffo

Journal:

Inorganica Chimica Acta

Year:

1985

Language:

english

File:

PDF, 1.16 MB

english, 1985

23

Structural studies of iron(III) complexes of the new iron-binding drug, pyridoxal isonicotinoyl hydrazone

Terrance B. Murphy, David K. Johnson, Norman J. Rose, Alejandro Aruffo, Verner Schomaker

Journal:

Inorganica Chimica Acta

Year:

1982

Language:

english

File:

PDF, 208 KB

english, 1982

24

CD6—ligand interactions: a paradigm for SRCR domain function?

Alejandro Aruffo, Michael A. Bowen, Dhavalkumar D. Patel, Barton F. Haynes, Gary C. Starling, John A. Gebe, Jürgen Bajorath

Journal:

Immunology Today

Year:

1997

Language:

english

File:

PDF, 1.08 MB

english, 1997

25

Therapeutic intervention with inhibitors of co-stimulatory pathways in autoimmune disease

Alejandro Aruffo, Diane Hollenbaugh

Journal:

Current Opinion in Immunology

Year:

2001

Language:

english

File:

PDF, 69 KB

english, 2001

26

CD44 binds to the Shigella IpaB protein and participates in bacterial invasion of epithelial cells

Anouchka Skoudy, Joelle Mounier, Alejandro Aruffo, Hélène Ohayon, Pierre Gounon, Philippe Sansonetti, Guy Tran Van Nhieu

Journal:

Cellular Microbiology

Year:

2000

Language:

english

File:

PDF, 431 KB

english, 2000

27

Knowledge-based model building of proteins: Concepts and examples

Jürgen Bajorath, Ronald Stenkamp, Alejandro Aruffo

Journal:

Protein Science

Year:

1993

Language:

english

File:

PDF, 3.97 MB

english, 1993

28

Molecular model of the N-terminal receptor-binding domain of the human CD6 ligand ALCAM

Jürgen Bajorath, Michael A. Bowen, Alejandro Aruffo

Journal:

Protein Science

Year:

1995

Language:

english

File:

PDF, 1.77 MB

english, 1995

29

Structure-based modeling of the ligand binding domain of the human cell surface receptor CD23 and comparison of two independently derived molecular models

Jürgen Bajorath, Alejandro Aruffo

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 3.27 MB

english, 1996

30

Classification of mutations in the human CD40 ligand, gp39, that are associated with X-linked hyper IgM syndrome

Jürgen Bajorath, Kuniaki Seyama, Shigeaki Nonoyama, Hans D. Ochs, Alejandro Aruffo

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 2.17 MB

english, 1996

31

CD6 recognizes the neural adhesion molecule BEN

John E. Skonier, Michael A. Bowen, Alejandro Aruffo, JÜRgen Bajorath

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 1.81 MB

english, 1997

32

Chromosomal localization of three human genes coding for A15, L6, and S5.7(TAPA1): all members of the transmembrane 4 superfamily of proteins

Kimmo I. Virtaneva, Nobuhiko Emi, John S. Marken, Alejandro Aruffo, Carol Jones, Nigel K. Spurr, Jim P. Schröder

Journal:

Year:

1994

Language:

english

File:

PDF, 599 KB

english, 1994

33

The molecular basis for T cell help in humoral immunity: CD40 and its ligand, gp39

Lisa S. Marshall, Alejandro Aruffo, Jeffrey A. Ledbetter, Randolph J. Noelle

Journal:

Journal of Clinical Immunology

Year:

1993

Language:

english

File:

PDF, 1.38 MB

english, 1993

34

Structural studies of Fe(III) and Cu(II) complexes of salycylaldehyde benzoyl hydrazone, a synthetic chelating agent exhibiting diverse biological properties

Alejandro A. Aruffo, Terrance B. Murphy, David K. Johnson, Norman J. Rose, Verner Schomaker

Journal:

Inorganica Chimica Acta

Year:

1982

Language:

english

File:

PDF, 242 KB

english, 1982

35

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

Larsen, Christian P., Elwood, Eric T., Alexander, Diane Z., Ritchie, Shannon C., Hendrix, Rose, Tucker-Burden, Carol, Cho, Hong Rae, Aruffo, Alejandro, Hollenbaugh, Diane, Linsley, Peter S.

Journal:

Year:

1996

File:

PDF, 1.60 MB

1996

36

The Role of CD40 and its Ligand in the Regulation of the Immune Response

Diane Hollenbaugh, Hans D. Ochs, Randolph J. Noelle, Jeffrey A. Ledbetter, Alejandro Aruffo

Journal:

Immunological Reviews

Year:

1994

Language:

english

File:

PDF, 4.89 MB

english, 1994

37

Prediction of the three-dimensional structure of the human Fas receptor by comparative molecular modeling

Jürgen Bajorath, Alejandro Aruffo

Journal:

Journal of Computer-Aided Molecular Design

Year:

1997

Language:

english

File:

PDF, 935 KB

english, 1997

38

Disruption of T Lymphocyte Reappearance in Anti-Thy-1-Treated Animals in Vivo with Soluble CD44 and L-Selectin Molecules

Ya-Jun Guo, Jin-Hong Wong, Shih-Chang Lin, Alejandro Aruffo, Ivan Stamenkovic, Man-Sun Sy

Journal:

Cellular Immunology

Year:

1994

File:

PDF, 635 KB

1994

39

Characterization of a CD6 Ligand(s) Expressed on Human- and Murine-Derived Cell Lines and Murine Lymphoid Tissues

Siow Fong Wee, Wei-Chun Wang, Andrew G. Farr, Andrew J. Nelson, Dhavalkumar D. Patel, Barton F. Haynes, Peter S. Linsley, Alejandro Aruffo

Journal:

Cellular Immunology

Year:

1994

File:

PDF, 475 KB

1994

40

Phorbol Ester-Induced Upregulation of Polymorphonuclear Leukocyte P-Selectin Ligand Expression

GORDON TODDERUD, JULIE ALFORD, ALEJANDRO ARUFFO, KENNETH M. TRAMPOSCH

Journal:

Cellular Immunology

Year:

1995

Language:

english

File:

PDF, 130 KB

english, 1995

41

Differential Regulation of CD40-Mediated Human B Cell Responses by Antibodies Directed against Different CD40 Epitopes

Naoki Sakata, Eckard Hamelmann, Anthony W. Siadak, Naohiro Terada, Pär Gerwins, Alejandro Aruffo, Gary L. Johnson, Erwin W. Gelfand

Journal:

Cellular Immunology

Year:

2000

Language:

english

File:

PDF, 455 KB

english, 2000

42

Cleavable CD40Ig fusion proteins and the binding to sgp39

Diane Hollenbaugh, Jean Douthwright, Vicki McDonald, Alejandro Aruffo

Journal:

Journal of Immunological Methods

Year:

1995

Language:

english

File:

PDF, 845 KB

english, 1995

43

CD40 ligand triggers interleukin-6 mediated B cell differentiation

Mitsuyoshi Urashima, Dharminder Chauhan, Maria Hatziyanni, Atsushi Ogata, Diane Hollenbaugh, Alejandro Aruffo, Kenneth C. Anderson

Journal:

Leukemia Research

Year:

1996

Language:

english

File:

PDF, 1.30 MB

english, 1996

44

Localization of hyaluronan in mouse embryos during implantation, gastrulation and organogenesis

Bruce A. Fenderson, Ivan Stamenkovic, Alejandro Aruffo

Journal:

Differentiation

Year:

1993

Language:

english

File:

PDF, 2.73 MB

english, 1993

45

Localization of hyaluronan in mouse embryos during implantation, gastrulation and organogenesis

Bruce A. Fenderson, Ivan Stamenkovic, Alejandro Aruffo

Journal:

Differentiation

Year:

1993

Language:

english

File:

PDF, 4.53 MB

english, 1993

46

Identification of the Tumor Antigen 90K Domains Recognized by Monoclonal Antibodies SP2 and L3 and Preparation and Characterization of Novel Anti-90K Monoclonal Antibodies

Nicola Tinari, Maurizia D'Egidio, Stefano Iacobelli, Michael Bowen, Gary Starling, Carrie Seachord, Richard Darveau, Alejandro Aruffo

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 709 KB

english, 1997

47

Retinoic Acid and Vitamin E Modulate Expression and Release of CD178 in Carcinoma Cells: Consequences for Induction of Apoptosis in CD95-Sensitive Cells

Helmut R. Salih, Gary C. Starling, Markus Knauff, Maj-Britt Llewellyn, Patricia M. Davis, William J. Pitts, Alejandro Aruffo, Peter A. Kiener

Journal:

Experimental Cell Research

Year:

2001

Language:

english

File:

PDF, 498 KB

english, 2001

48

The role of CD40L (gp39)/CD40 in T/B cell interaction and primary immunodeficiency

Hans D. Ochs, Diane Hollenbaugh, Alejandro Aruffo

Journal:

Seminars in Immunology

Year:

1994

File:

PDF, 329 KB

1994

49

Interactions between oncostatin M and the IL-6 signal transducer, gp130

Jingwen Liu, Brett Modrell, Alejandro Aruffo, Sonya Scharnowske, Mohammed Shoyab

Journal:

Year:

1994

Language:

english

File:

PDF, 1.21 MB

english, 1994

50

In the absence of a CD40 signal, B cells are tolerogenic

Janet E. Suhlmann, Teresa M. Foy, Alejandro Aruffo, Karen M. Crassi, Jeffrey A. Ledbetter, William R. Green, Jianchao C. Xu, Leonard D. Shultz, Derry Roopeslan, Richard A. Flavell, Loren Fast, Randolp

Journal:

Year:

1995

Language:

english

File:

PDF, 987 KB

english, 1995