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51

Combining cytokine-induced killer cells with vaccination in cancer immunotherapy: More than one plus one?

Sharmilan Thanendrarajan, Michael Nowak, Hinrich Abken, Ingo G.H. Schmidt-Wolf

Journal:

Leukemia Research

Year:

2011

Language:

english

File:

PDF, 374 KB

english, 2011

52

Isolation of single chain antibody fragments with specificity for cell surface antigens by phage display utilizing internal image anti-idiotypic antibodies

Andreas Hombach, Christoph Pohl, Claudia Heuser, Ranjan Sircar, Volker Diehl, Hinrich Abken

Journal:

Journal of Immunological Methods

Year:

1998

Language:

english

File:

PDF, 201 KB

english, 1998

53

Sputtered Mo/Sb2Te3 and Ni/Sb2Te3 layers as back contacts for CdTe/CdS solar cells

A.E Abken, O.J Bartelt

Journal:

Thin Solid Films

Year:

2002

Language:

english

File:

PDF, 181 KB

english, 2002

54

Inhibition of membrane-bound electron transport of the methanogenic archaeon Methanosarcina mazei Gö1 by diphenyleneiodonium

Jens Brodersen, , Sebastian Bäumer, , Hans-Jörg Abken, , Gerhard Gottschalk, Uwe Deppenmeier

Journal:

Year:

1999

Language:

english

File:

PDF, 400 KB

english, 1999

55

AGGRESSIVE HEPATITIS IN A PATIENT WITH ACUTE MYELOID LEUKAEMIA DURING COMPLETE REMISSION AND DETECTION OF EPSTEIN-BARR VIRUS DNA IN A LIVER BIOPSY

R. Donhuijsen-Ant, H. Abken, M. Westerhausen, J. Kuupper, B. Miller, H.-J. Knieriem, D. Neumann-Haefelin

Journal:

British Journal of Haematology

Year:

1990

Language:

english

File:

PDF, 270 KB

english, 1990

56

Cutaneous T-cell lymphoma: Molecular genetics, immunology and pathogenesis

U. Reinhold, H. Abken

Journal:

European Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 1.06 MB

english, 1995

57

The complex role of B7 molecules in tumor immunology

Barbara Seliger, Francesco M. Marincola, Soldano Ferrone, Hinrich Abken

Journal:

Trends in Molecular Medicine

Year:

2008

Language:

english

File:

PDF, 398 KB

english, 2008

58

[97] T CELLS REDIRECTED AGAINST HEPATITIS B VIRUS SURFACE PROTEINS ELIMINATE INFECTED HEPATOCYTES

F. Bonne, M. Chmielewski, G. Ebert, A. Schulze, S. Urban, T. Kiirschner, H. Abken, U. Protzer

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 151 KB

english, 2007

59

Chimeric T-cell receptors: highly specific tools to target cytotoxic T-lymphocytes to tumour cells

H. Abken, A. Hombach, C. Heuser, R. Sircar, C. Pohl, U. Reinhold

Journal:

Cancer Treatment Reviews

Year:

1997

Language:

english

File:

PDF, 1.61 MB

english, 1997

60

Purification and properties of an F420H2 dehydrogenase from Methanosarcina mazei Gö1

Hans-Jörg Abken, Uwe Deppenmeier

Journal:

FEMS Microbiology Letters

Year:

1997

Language:

english

File:

PDF, 918 KB

english, 1997

61

In vitro display of DNA elements that modulate the RNA transcription in cis or in trans directions

Barbara Reifenrath-Biesel, Hinrich Abken

Journal:

Year:

1996

Language:

english

File:

PDF, 309 KB

english, 1996

62

62 Proffered Paper: Regression of Metastatic Melanoma by Targeting Melanoma Stem Cells

H. Abken, P. Schmidt, M. Schlaak, A.A. Hombach, C. Bangard, P. Kurschat, P. Zigrino

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 51 KB

english, 2012

63

Tuning tumor-specific T-cell activation: a matter of costimulation?

Hinrich Abken, Andreas Hombach, Claudia Heuser, Kai Kronfeld, Barbara Seliger

Journal:

Trends in Immunology

Year:

2002

Language:

english

File:

PDF, 50 KB

english, 2002

64

HLA-G and MIC expression in tumors and their role in anti-tumor immunity

Barbara Seliger, Hinrich Abken, Soldano Ferrone

Journal:

Trends in Immunology

Year:

2003

Language:

english

File:

PDF, 740 KB

english, 2003

65

CD4+CD7− T cells compose the dominant T-cell clone in the peripheral blood of patients with Sézary syndrome

Gunter Rappl, Joachim Marcus Muche, Hinrich Abken, Wolfram Sterry, Wolfgang Tilgen, Selma Ugurel, Uwe Reinhold

Journal:

Journal of the American Academy of Dermatology

Year:

2001

Language:

english

File:

PDF, 147 KB

english, 2001

66

Rational development of high-affinity T-cell receptor-like antibodies

Stewart-Jones, G., Wadle, A., Hombach, A., Shenderov, E., Held, G., Fischer, E., Kleber, S., Nuber, N., Stenner-Liewen, F., Bauer, S., McMichael, A., Knuth, A., Abken, H., Hombach, A. A., Cerundolo, V

Journal:

Proceedings of the National Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 771 KB

english, 2009

67

T Cells Redirected Against Hepatitis B Virus Surface Proteins Eliminate Infected Hepatocytes

Felix Bohne, Markus Chmielewski, Gregor Ebert, Katja Wiegmann, Timo Kürschner, Andreas Schulze, Stephan Urban, Martin Krönke, Hinrich Abken, Ulrike Protzer

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 1.42 MB

english, 2008

68

A fluorometric assay to monitor mitogenic stimulation of human lymphocytes

Ralf Bialek, Hinrich Abken

Journal:

Journal of Immunological Methods

Year:

1991

Language:

english

File:

PDF, 457 KB

english, 1991

69

Fas ligand expression in normal and neoplastic cells of melanocytic origin

Rappl, Gunter, Seiter, Simone, Ugurel, Selma, Tilgen, Wolfgang, Abken, Hinrich, Reinhold, Uwe

Journal:

Journal of Dermatological Science

Year:

1998

Language:

english

File:

PDF, 155 KB

english, 1998

70

Anti-idiotypic monoclonal antibodies enhance the in-vitro cytotoxicity of CTL targeted to melanoma cells by Grafted chimeric receptors

Reinhold, Uwe, Liu, Lide, Heuser, Claudia, Hombach, Andreas, Ferrone, Soldano, Abken, Hinrich

Journal:

Journal of Dermatological Science

Year:

1998

Language:

english

File:

PDF, 203 KB

english, 1998

71

T cell targeting of TAG72+ tumor cells by a chimeric receptor with antibody-like specificity for a carbohydrate epitope

A Hombach, C Heuser, R Sircar, T Tillmann, V Diehl, W Kruis, C Pohl, H Abken

Journal:

Gastroenterology

Year:

1997

Language:

english

File:

PDF, 341 KB

english, 1997

72

T Cells That Target Carcinoembryonic Antigen Eradicate Orthotopic Pancreatic Carcinomas Without Inducing Autoimmune Colitis in Mice

Markus Chmielewski, Olga Hahn, Gunter Rappl, Michael Nowak, Ingo H. Schmidt–Wolf, Andreas A. Hombach, Hinrich Abken

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 5.36 MB

english, 2012

73

Redirected T Cells That Target Pancreatic Adenocarcinoma Antigens Eliminate Tumors and Metastases in Mice

Amit Maliar, Charlotte Servais, Tova Waks, Markus Chmielewski, Ron Lavy, Peter Altevogt, Hinrich Abken, Zelig Eshhar

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 3.16 MB

english, 2012

74

A DNA-Binding Zinc-Protein Increases the Immortalizing Activity of an Extrachromosomal DNA Sequence from Mouse L929 Cells

HINRICH ABKEN, RALF HEGGER, KLAUS WILLECKE

Journal:

Annals of the New York Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 195 KB

english, 1993

75

Photoluminescence study of polycrystalline photovoltaic CdS thin film layers grown by close-spaced sublimation and chemical bath deposition

Abken, Anke E., Halliday, D. P., Durose, Ken

Journal:

Journal of Applied Physics

Year:

2009

Language:

english

File:

PDF, 706 KB

english, 2009

76

T Cells Expressing a Chimeric Antigen Receptor That Binds Hepatitis B Virus Envelope Proteins Control Virus Replication in Mice

Krebs, Karin, Böttinger, Nina, Huang, Li–Rung, Chmielewski, Markus, Arzberger, Silke, Gasteiger, Georg, Jäger, Clemens, Schmitt, Edgar, Bohne, Felix, Aichler, Michaela, Uckert, Wolfgang, Abken, Hinric

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 482 KB

english, 2013

77

Second mitochondria-derived activator of caspase (SMAC) mimetic potentiates tumor susceptibility toward natural killer cell-mediated killing

Brinkmann, Kerstin, Hombach, Andreas, Seeger, Jens Michael, Wagner-Stippich, Diana, Klubertz, Daniela, Krönke, Martin, Abken, Hinrich, Kashkar, Hamid

Journal:

Leukemia and Lymphoma

Year:

2014

Language:

english

File:

PDF, 1.44 MB

english, 2014

78

Arming cytokine induced killer cells with chimeric antigen receptors (CARs): CD28 outperforms combined CD28-OX40 "super-stimulation"

Hombach, Andreas A., Rappl, Gunter, Abken, Hinrich

Journal:

Molecular Therapy

Year:

2013

Language:

english

File:

PDF, 783 KB

english, 2013

79

Development of Adoptive Cell Therapy for Cancer: A Clinical Perspective

Hawkins, Robert E., Gilham, David E., Debets, Reno, Eshhar, Zelig, Taylor, Naomi, Abken, Hinrich, Schumacher, Ton N.

Journal:

Human Gene Therapy

Year:

2010

Language:

english

File:

PDF, 1.73 MB

english, 2010

80

T cells redirected by a chimeric antigen receptor recognizing HBsAg efficiently control HBV in vivo in transgenic mice

Krebs, K., Böttinger, N., Huang, L., Chmielewski, M., Uckert, W., Abken, H., Heikenwälder, M., Knolle, P., Protzer, U.

Journal:

Year:

2014

Language:

english

File:

PDF, 238 KB

english, 2014

81

A chimeric receptor that selectively targets membrane-bound carcinoembryonic antigen (mCEA) in the presence of soluble CEA

Pohl, C., Hombach, A., Heuser, C., Sircar, R., Tillmann, T., Diehl, V., Kruis, W., Abken, H.

Journal:

Gastroenterology

Year:

1998

Language:

english

File:

PDF, 161 KB

english, 1998

82

340 T CELLS REDIRECTED BY A CHIMERIC ANTIGEN RECEPTOR RECOGNIZING HBsAg EFFICIENTLY CONTROL HBV IN VIVO IN TRANSGENIC MICE

Krebs, K., Böttinger, N., Huang, L.-R., Chmielewski, M., Arzberger, S., Gasteiger, G., Schmitt, E., Bohne, F., Aichler, M., Uckert, W., Abken, H., Heikenwälder, M., Knolle, P., Protzer, U.

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 69 KB

english, 2013

83

Expression of chimeric IgG-ξ and IgG-λ receptors with specificity for TAG72

Hombach, A., Pohl, C., Heuser, C., Sircar, R., Tillman, T., Diehl, V., Kruis, W., Abken, H.

Journal:

Gastroenterology

Year:

1998

Language:

english

File:

PDF, 176 KB

english, 1998

84

Immortalization of Human Lymphocytes by Transfection with DNA from Mouse L929 Cytoplasts

Hinrich Abken, Christoph Bützler and Klaus Willecke

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 1.26 MB

english, 1988

85

Immortalization of Human Lymphocytes by Fusion with Cytoplasts of Transformed Mouse L Cells

Hinrich Abken, Herbert Jungfer, Winfried H. W. Albert and Klaus Willecke

Journal:

The Journal of Cell Biology

Year:

1986

Language:

english

File:

PDF, 3.23 MB

english, 1986

86

A GMP-compliant protocol to expand and transfect cancer patient T cells with mRNA encoding a tumor-specific chimeric antigen receptor

Krug, Christian, Wiesinger, Manuel, Abken, Hinrich, Schuler-Thurner, Beatrice, Schuler, Gerold, Dörrie, Jan, Schaft, Niels

Journal:

Cancer Immunology, Immunotherapy

Year:

2014

Language:

english

File:

PDF, 421 KB

english, 2014

87

S80. Prolongation of T cell response by OX40 co-signalling CARS

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2014

Language:

english

File:

PDF, 72 KB

english, 2014

88

Adoptive Immunotherapy with Redirected T Cells Produces CCR7 − Cells That Are Trapped in the Periphery and Benefit from Combined CD28-OX40 Costimulation

Hombach, Andreas A., Chmielewski, Markus, Rappl, Gunter, Abken, Hinrich

Journal:

Human Gene Therapy

Year:

2013

Language:

english

File:

PDF, 831 KB

english, 2013

89

Extensive Amplification of Human Regulatory T Cells Alters Their Functional Capacities and Targets Them to the Periphery

Rappl, Gunter, Schmidt, Annette, Mauch, Cornelia, Hombach, Andreas A., Abken, Hinrich

Journal:

Rejuvenation Research

Year:

2008

Language:

english

File:

PDF, 12.55 MB

english, 2008

90

An anti-MUC1-antibody–interleukin-2 fusion protein that activates resting NK cells to lysis of MUC1-positive tumour cells

Heuser, C, Ganser, M, Hombach, A, Brand, H, Denton, G, Hanisch, F-G, Abken, H

Journal:

British Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 195 KB

english, 2003

91

Grafting T Cells with Tumor Specificity: The Chimeric Receptor Strategy for Use in Immunotherapy of Malignant Diseases

HOMBACH, ANDREAS, POHL, CHRISTOPH, REINHOLD, UWE, ABKEN, HINRICH

Journal:

Year:

1999

Language:

english

File:

PDF, 712 KB

english, 1999

92

Selective Bispecific T Cell Recruiting Antibody and Antitumor Activity of Adoptive T Cell Transfer

Kobold, S., Steffen, J., Chaloupka, M., Grassmann, S., Henkel, J., Castoldi, R., Zeng, Y., Chmielewski, M., Schmollinger, J. C., Schnurr, M., Rothenfusser, S., Schendel, D. J., Abken, H., Sustmann, C.

Journal:

JNCI Journal of the National Cancer Institute

Year:

2014

Language:

english

File:

PDF, 910 KB

english, 2014

93

Do CARs Need a Driver's License? Adoptive Cell Therapy with Chimeric Antigen Receptor-Redirected T Cells Has Caused Serious Adverse Events

Büning, Hildegard, Uckert, Wolfgang, Cichutek, Klaus, Hawkins, Robert E., Abken, Hinrich

Journal:

Human Gene Therapy

Year:

2010

Language:

english

File:

PDF, 95 KB

english, 2010

94

CD7 − T Cells are Late Memory Cells Generated from CD7 + T Cells

Rappl, Gunter, Schrama, David, Hombach, Andreas, Meuer, Eva Katharina, Schmidt, Annette, Becker, Jürgen C., Abken, Hinrich

Journal:

Rejuvenation Research

Year:

2008

Language:

english

File:

PDF, 1.19 MB

english, 2008

95

263. Antigen-Specific and MHC-Independent Tumor Cell Lysis by Redirected Human CD4+ T Cells Grafted with an Antibody-Type Immunoreceptor

Hombach, Andreas, Koehler, Heike, Rappl, Gunter, Abken, Hinrich

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

96

798. Epstein Barr Virus-Specific Cytotoxic T Lymphocytes (EBV-CTL) Expressing an Anti-CD30 Chimeric T-Cell Receptor (cTcR) for the Treatment of Hodgkin's Disease (HD)

SAVOLDO, B, ROONEY, C, HESLOP, H, ABKEN, H, HOMBACH, A, ZHANG, L, PULE, M, DOTTI, G, BRENNER, M

Journal:

Molecular Therapy

Year:

2005

Language:

english

File:

PDF, 80 KB

english, 2005

97

Targeting two co-operating cytokines efficiently shapes immune responses

Hombach, Andreas A., Abken, Hinrich

Journal:

Year:

2013

Language:

english

File:

PDF, 242 KB

english, 2013

98

Receptor-targeted lentiviral vectors are exceptionally sensitive toward the biophysical properties of the displayed single-chain Fv

Friedel, T., Hanisch, L. J., Muth, A., Honegger, A., Abken, H., Pluckthun, A., Buchholz, C. J., Schneider, I. C.

Journal:

Protein Engineering Design and Selection

Year:

2015

Language:

english

File:

PDF, 1.13 MB

english, 2015

99

Eradication of melanomas by targeted elimination of a minor subset of tumor cells

Schmidt, P., Kopecky, C., Hombach, A., Zigrino, P., Mauch, C., Abken, H.

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.19 MB

english, 2011

100

T Cell Activation by Antibody-Like Immunoreceptors: The Position of the Binding Epitope within the Target Molecule Determines the Efficiency of Activation of Redirected T Cells

Hombach, A. A., Schildgen, V., Heuser, C., Finnern, R., Gilham, D. E., Abken, H.

Journal:

The Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 533 KB

english, 2007

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