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1

Mucosal boosting of H56:CAF01 immunization promotes lung-localized T cells and an accelerated pulmonary response to Mycobacterium tuberculosis infection without enhancing vaccine protection

Woodworth, Joshua S., Christensen, Dennis, Cassidy, Joseph P., Agger, Else Marie, Mortensen, Rasmus, Andersen, Peter

Journal:

Mucosal Immunology

Year:

2019

Language:

english

File:

PDF, 2.90 MB

english, 2019

2

Cationic liposomes as vaccine adjuvants

Christensen, Dennis, Korsholm, Karen S, Rosenkrands, Ida, Lindenstrøm, Thomas, Andersen, Peter, Agger, Else Marie

Journal:

Expert Review of Vaccines

Year:

2007

Language:

english

File:

PDF, 571 KB

english, 2007

3

Re-formulation of selected DNA vaccine candidates and their evaluation as protein vaccines using a guinea pig aerosol infection model of tuberculosis

Julia Vipond, Simon O. Clark, Graham J. Hatch, Richard Vipond, Else Marie Agger, Julia A. Tree, Ann Williams, Philip D. Marsh

Journal:

Year:

2006

Language:

english

File:

PDF, 149 KB

english, 2006

4

High Antigen Dose Is Detrimental to Post-Exposure Vaccine Protection against Tuberculosis

Billeskov, Rolf, Lindenstrøm, Thomas, Woodworth, Joshua, Vilaplana, Cristina, Cardona, Pere-Joan, Cassidy, Joseph P., Mortensen, Rasmus, Agger, Else Marie, Andersen, Peter

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 2.46 MB

english, 2018

5

Subunit vaccines: Distearoylphosphatidylcholine-based liposomes entrapping antigen offer a neutral alternative to dimethyldioctadecylammonium-based cationic liposomes as an adjuvant delivery system

Sarah E. McNeil, Ida Rosenkrands, Else Marie Agger, Peter Andersen, Yvonne Perrie

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 236 KB

english, 2011

6

Adjuvant properties of a simplified C32 monomycolyl glycerol analogue

Veemal Bhowruth, David E. Minnikin, Else Marie Agger, Peter Andersen, Vincent W. Bramwell, Yvonne Perrie, Gurdyal S. Besra

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 274 KB

english, 2009

7

Anti-tumoral effect of active immunotherapy in C57BL/6 mice using a recombinant human VEGF protein as antigen and three chemically unrelated adjuvants

Yanelys Morera, Mónica Bequet-Romero, Marta Ayala, Humberto Lamdán, Else-Marie Agger, Peter Andersen, Jorge V. Gavilondo

Journal:

Year:

2008

Language:

english

File:

PDF, 406 KB

english, 2008

8

Incorporation of the TLR4 Agonist Monophosphoryl Lipid A Into the Bilayer of DDA/TDB Liposomes: Physico-Chemical Characterization and Induction of CD8+T-Cell ResponsesIn Vivo

Pernille Nordly, Else Marie Agger, Peter Andersen, Hanne Mørck Nielsen, Camilla Foged

Journal:

Pharmaceutical Research

Year:

2011

Language:

english

File:

PDF, 282 KB

english, 2011

9

CAF01 liposomes as a mucosal vaccine adjuvant: In vitro and in vivo investigations

Dennis Christensen, Camilla Foged, Ida Rosenkrands, Carina Vingsbo Lundberg, Peter Andersen, Else Marie Agger, Hanne Mørck Nielsen

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 500 KB

english, 2010

10

Human T-cell responses to the RD1-encoded protein TB27.4 (Rv3878) from Mycobacterium tuberculosis

Else Marie Agger, Inger Brock, Limei Meng Okkels, Sandra M. Arend, Claus S. Aagaard, Karin N. Weldingh, Peter Andersen

Journal:

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

11

The adjuvant mechanism of cationic dimethyldioctadecylammonium liposomes

Karen Smith Korsholm, Else Marie Agger, Camilla Foged, Dennis Christensen, Jes Dietrich, Claire Swetman Andersen, Carsten Geisler, Peter Andersen

Journal:

Year:

2007

Language:

english

File:

PDF, 825 KB

english, 2007

12

Adjuvant modulation of the cytokine balance in Mycobacterium tuberculosis subunit vaccines; immunity, pathology and protection

Else Marie Agger, Joseph P. Cassidy, Joseph Brady, Karen S. Korsholm, Carina Vingsbo-Lundberg, Peter Andersen

Journal:

Year:

2008

Language:

english

File:

PDF, 896 KB

english, 2008

13

T-helper 1 and T-helper 2 adjuvants induce distinct differences in the magnitude, quality and kinetics of the early inflammatory response at the site of injection

Karen Smith Korsholm, Rune V. Petersen, Else Marie Agger, Peter Andersen

Journal:

Year:

2010

Language:

english

File:

PDF, 465 KB

english, 2010

14

A comparative study of cationic liposome and niosome-based adjuvant systems for protein subunit vaccines: characterisation, environmental scanning electron microscopy and immunisation studies in mice

Anil Vangala, Daniel Kirby, Ida Rosenkrands, Else Marie Agger, Peter Andersen, Yvonne Perrie

Journal:

Journal of Pharmacy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 5.56 MB

english, 2006

15

CAF05: cationic liposomes that incorporate synthetic cord factor and poly(I:C) induce CTL immunity and reduce tumor burden in mice

Jon Hansen, Thomas Lindenstrøm, Julie Lindberg-Levin, Claus Aagaard, Peter Andersen, Else Marie Agger

Journal:

Cancer Immunology, Immunotherapy

Year:

2012

Language:

english

File:

PDF, 634 KB

english, 2012

16

License to kill: Formulation requirements for optimal priming of CD8+ CTL responses with particulate vaccine delivery systems

Camilla Foged, Jon Hansen, Else Marie Agger

Journal:

European Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 513 KB

english, 2012

17

Comparison of vesicle based antigen delivery systems for delivery of hepatitis B surface antigen

Anil Vangala, Vincent W. Bramwell, Sarah McNeil, Dennis Christensen, Else Marie Agger, Yvonne Perrie

Journal:

Journal of Controlled Release

Year:

2007

Language:

english

File:

PDF, 482 KB

english, 2007

18

Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen

Malou Henriksen-Lacey, Vincent W. Bramwell, Dennis Christensen, Else-Marie Agger, Peter Andersen, Yvonne Perrie

Journal:

Journal of Controlled Release

Year:

2010

Language:

english

File:

PDF, 433 KB

english, 2010

19

Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce a CMI response

Malou Henriksen-Lacey, Dennis Christensen, Vincent W. Bramwell, Thomas Lindenstrøm, Else Marie Agger, Peter Andersen, Yvonne Perrie

Journal:

Journal of Controlled Release

Year:

2010

Language:

english

File:

PDF, 685 KB

english, 2010

20

Immunity by formulation design: Induction of high CD8+ T-cell responses by poly(I:C) incorporated into the CAF01 adjuvant via a double emulsion method

Pernille Nordly, Fabrice Rose, Dennis Christensen, Hanne Mørck Nielsen, Peter Andersen, Else Marie Agger, Camilla Foged

Journal:

Journal of Controlled Release

Year:

2011

Language:

english

File:

PDF, 1.23 MB

english, 2011

21

Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6,6′-dibehenate)—A novel adjuvant inducing both strong CMI and antibody responses

Jesper Davidsen, Ida Rosenkrands, Dennis Christensen, Anil Vangala, Daniel Kirby, Yvonne Perrie, Else Marie Agger, Peter Andersen

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2005

Language:

english

File:

PDF, 605 KB

english, 2005

22

Trehalose preserves DDA/TDB liposomes and their adjuvant effect during freeze-drying

Dennis Christensen, Camilla Foged, Ida Rosenkrands, Hanne Mørck Nielsen, Peter Andersen, Else Marie Agger

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2007

Language:

english

File:

PDF, 723 KB

english, 2007

23

α,α′-trehalose 6,6′-dibehenate in non-phospholipid-based liposomes enables direct interaction with trehalose, offering stability during freeze-drying

Dennis Christensen, Daniel Kirby, Camilla Foged, Else Marie Agger, Peter Andersen, Yvonne Perrie, Hanne Mørck Nielsen

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2008

Language:

english

File:

PDF, 234 KB

english, 2008

24

NIR transmission spectroscopy for rapid determination of lipid and lyoprotector content in liposomal vaccine adjuvant system CAF01

Dennis Christensen, Morten Allesø, Ida Rosenkrands, Jukka Rantanen, Camilla Foged, Else Marie Agger, Peter Andersen, Hanne Mørck Nielsen

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2008

Language:

english

File:

PDF, 234 KB

english, 2008

25

Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo

Pernille Nordly, Karen Smith Korsholm, Esra Alici Pedersen, Tayba Sajid Khilji, Henrik Franzyk, Lene Jorgensen, Hanne Mørck Nielsen, Else Marie Agger, Camilla Foged

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2011

Language:

english

File:

PDF, 531 KB

english, 2011

26

Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6

Jan A.M. Langermans, T. Mark Doherty, Richard A.W. Vervenne, Tridia van der Laan, Konstantin Lyashchenko, Rena Greenwald, Else Marie Agger, Claus Aagaard, Horst Weiler, Dick van Soolingen, Wilfried Da

Journal:

Year:

2005

Language:

english

File:

PDF, 564 KB

english, 2005

27

Protective immunity to tuberculosis with Ag85B-ESAT-6 in a synthetic cationic adjuvant system IC31

Else Marie Agger, Ida Rosenkrands, Anja Weinreich Olsen, Graham Hatch, Ann Williams, Constantia Kritsch, Karen Lingnau, Alexander von Gabain, Claire Swetman Andersen, Karen Smith Korsholm, Peter Ander

Journal:

Year:

2006

Language:

english

File:

PDF, 360 KB

english, 2006

28

Enhanced humoral and cell-mediated immune responses after immunization with trivalent influenza vaccine adjuvanted with cationic liposomes

Ida Rosenkrands, Carina Vingsbo-Lundberg, Trine Junker Bundgaard, Thomas Lindenstrøm, Vincent Enouf, Sylvie van der Werf, Peter Andersen, Else Marie Agger

Journal:

Year:

2011

Language:

english

File:

PDF, 431 KB

english, 2011

29

A new adjuvant enhances the protection of the commercial influenza vaccine in the ferret model

Cyril J. Martel, Trine H. Jensen, Lars P. Nielsen, Birgitte Viuff, Else-Marie Agger, Merete Blixenkrone-Møller, Peter Andersen, Bent Aasted

Journal:

Veterinary Immunology and Immunopathology

Year:

2009

Language:

english

File:

PDF, 92 KB

english, 2009

30

Dendritic Cells Prevent Rather Than Promote Immunity Conferred by a Helicobacter Vaccine Using a Mycobacterial Adjuvant

Iris Hitzler, Mathias Oertli, Burkhard Becher, Else Marie Agger, Anne Müller

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 3.89 MB

english, 2011

31

Cationic Liposomes Formulated with Synthetic Mycobacterial Cordfactor (CAF01): A Versatile Adjuvant for Vaccines with Different Immunological Requirements

Agger, Else Marie, Rosenkrands, Ida, Hansen, Jon, Brahimi, Karima, Vandahl, Brian S., Aagaard, Claus, Werninghaus, Kerstin, Kirschning, Carsten, Lang, Roland, Christensen, Dennis, Theisen, Michael, Fo

Journal:

Year:

2008

Language:

english

File:

PDF, 403 KB

english, 2008

32

Cationic liposomes as vaccine adjuvants

Christensen, Dennis, Korsholm, Karen Smith, Andersen, Peter, Agger, Else Marie

Journal:

Expert Review of Vaccines

Year:

2011

Language:

english

File:

PDF, 2.41 MB

english, 2011

33

The Physical Stability of the Recombinant Tuberculosis Fusion Antigens H1 and H56

Hamborg, Mette, Kramer, Ryan, Schanté, Carole E., Agger, Else Marie, Christensen, Dennis, Jorgensen, Lene, Foged, Camilla, Middaugh, C. Russell

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 3.26 MB

english, 2013

34

Comparison of the Depot Effect and Immunogenicity of Liposomes Based on Dimethyldioctadecylammonium (DDA), 3β-[ N -( N ′, N ′-Dimethylaminoethane)carbomyl] Cholesterol (DC-Chol), and 1,2-Dioleoyl-3-trimethylammonium Propane (DOTAP): Prolonged Liposome Retention Mediates Stronger Th1 Responses

Henriksen-Lacey, Malou, Christensen, Dennis, Bramwell, Vincent W., Lindenstrøm, Thomas, Agger, Else Marie, Andersen, Peter, Perrie, Yvonne

Journal:

Molecular Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 1.84 MB

english, 2011

35

Human B cells produce chemokine CXCL10 in the presence of Mycobacterium tuberculosis specific T cells

Hoff, Soren T., Salman, Ahmed M., Ruhwald, Morten, Ravn, Pernille, Brock, Inger, Elsheikh, Nabila, Andersen, Peter, Agger, Else Marie

Journal:

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

36

Protein Energy Malnutrition during Vaccination Has Limited Influence on Vaccine Efficacy but Abolishes Immunity if Administered during Mycobacterium tuberculosis Infection

Hoang, Truc, Agger, Else Marie, Cassidy, Joseph P., Christensen, Jan P., Andersen, Peter, Ehrt, S.

Journal:

Infection and Immunity

Year:

2015

Language:

english

File:

PDF, 1.37 MB

english, 2015

37

A Liposome-Based Mycobacterial Vaccine Induces Potent Adult and Neonatal Multifunctional T Cells through the Exquisite Targeting of Dendritic Cells

Kamath, Arun T., Rochat, Anne-Françoise, Christensen, Dennis, Agger, Else Marie, Andersen, Peter, Lambert, Paul-Henri, Siegrist, Claire-Anne, Unutmaz, Derya

Journal:

Year:

2009

Language:

english

File:

PDF, 664 KB

english, 2009

38

Liposome Delivery of Chlamydia muridarum Major Outer Membrane Protein Primes a Th1 Response That Protects against Genital Chlamydial Infection in a Mouse Model1

Hansen, Jon, Jensen, Klaus Thorleif, Follmann, Frank, Agger, Else Marie, Theisen, Michael, Andersen, Peter

Journal:

The Journal of Infectious Diseases

Year:

2008

Language:

english

File:

PDF, 683 KB

english, 2008

39

Aluminium hydroxide potentiates a protective Th1 biased immune response against polio virus that allows for dose sparing in mice and rats

Andreasen, Lars Vibe, Hansen, Lasse Bøllehuus, Andersen, Peter, Agger, Else Marie, Dietrich, Jes

Journal:

Year:

2015

Language:

english

File:

PDF, 1.45 MB

english, 2015

40

Antigen Discovery and Tuberculosis Vaccine Development in the Post-genomic Era

Skjøt, Rikke Louise Vinther, Agger, Else Marie, Andersen, Peter

Journal:

Scandinavian Journal of Infectious Diseases

Year:

2001

Language:

english

File:

PDF, 145 KB

english, 2001

41

Liposome-based cationic adjuvant formulations (CAF): Past, present, and future

Christensen, Dennis, Agger, Else Marie, Andreasen, Lars Vibe, Kirby, Daniel, Andersen, Peter, Perrie, Yvonne

Journal:

Journal of Liposome Research

Year:

2009

Language:

english

File:

PDF, 289 KB

english, 2009

42

Novel adjuvant formulations for delivery of anti-tuberculosis vaccine candidates

Agger, Else Marie

Journal:

Advanced Drug Delivery Reviews

Year:

2015

Language:

english

File:

PDF, 593 KB

english, 2015

43

The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons

Carroll, Elizabeth. C., Jin, Lei, Mori, Andres, Muñoz-Wolf, Natalia, Oleszycka, Ewa, Moran, Hannah B.T., Mansouri, Samira, McEntee, Craig P., Lambe, Eimear, Agger, Else Marie, Andersen, Peter, Cunning

Journal:

Year:

2016

File:

PDF, 3.22 MB

2016

44

The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons

Carroll, Elizabeth. C., Jin, Lei, Mori, Andres, Muñoz-Wolf, Natalia, Oleszycka, Ewa, Moran, Hannah B.T., Mansouri, Samira, McEntee, Craig P., Lambe, Eimear, Agger, Else Marie, Andersen, Peter, Cunning

Journal:

Year:

2016

Language:

english

File:

PDF, 3.22 MB

english, 2016

45

Host immunity to Mycobacterium tuberculosis and risk of tuberculosis: A longitudinal study among Greenlanders

Michelsen, Sascha Wilk, Soborg, Bolette, Agger, Else Marie, Diaz, Lars Jorge, Hoff, Soren Tetens, Koch, Anders, Sorensen, Hans Christian Florian, Andersen, Peter, Wohlfahrt, Jan, Melbye, Mads

Journal:

Year:

2016

Language:

english

File:

PDF, 931 KB

english, 2016

46

Low Antigen Dose in Adjuvant-Based Vaccination Selectively Induces CD4 T Cells with Enhanced Functional Avidity and Protective Efficacy

Billeskov, Rolf, Wang, Yichuan, Solaymani-Mohammadi, Shahram, Frey, Blake, Kulkarni, Shweta, Andersen, Peter, Agger, Else Marie, Sui, Yongjun, Berzofsky, Jay A.

Journal:

The Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 2.12 MB

english, 2017

47

Broadening CD4 + and CD8 + T cell responses against hepatitis C virus by vaccination with NS3 overlapping peptide panels in cross-priming liposomes

Filskov, Jonathan, Mikkelsen, Marianne, Hansen, Paul R., Christensen, Jan P., Thomsen, Allan R., Andersen, Peter, Bukh, Jens, Agger, Else Marie

Journal:

Journal of Virology

Year:

2017

Language:

english

File:

PDF, 2.66 MB

english, 2017

48

T Cells Primed by Live Mycobacteria Versus a Tuberculosis Subunit Vaccine Exhibit Distinct Functional Properties

Lindenstrøm, Thomas, Moguche, Albanus, Damborg, Mie, Agger, Else Marie, Urdahl, Kevin, Andersen, Peter

Journal:

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

49

A Novel Liposome-Based Adjuvant CAF01 for Induction of CD8+ Cytotoxic T-Lymphocytes (CTL) to HIV-1 Minimal CTL Peptides in HLA-A*0201 Transgenic Mice

Gram, Gregers Jacob, Karlsson, Ingrid, Agger, Else Marie, Andersen, Peter, Fomsgaard, Anders, Unutmaz, Derya

Journal:

Year:

2009

Language:

english

File:

PDF, 194 KB

english, 2009

50

Syringe Free Vaccination with CAF01 Adjuvated Ag85B-ESAT-6 in Bioneedles Provides Strong and Prolonged Protection Against Tuberculosis

Christensen, Dennis, Lindenstrøm, Thomas, van de Wijdeven, Gijsbert, Andersen, Peter, Agger, Else Marie, Cardona, Pere-Joan

Journal:

Year:

2010

Language:

english

File:

PDF, 394 KB

english, 2010