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51

Investigation of the allene oxide pathway in the coral Plexaura homomalla: Formation of novel ketols and isomers of prostaglandin A2 from 15-hydroxyeicosatetraenoic acid

Wen-Chao Song, Alan R. Brash

Journal:

Archives of Biochemistry and Biophysics

Year:

1991

Language:

english

File:

PDF, 848 KB

english, 1991

52

The identification of 5β,7α-dihydroxy-11-oxotetranor-prostane-1, 16-dioic acid as a urinary metabolite of prostaglandin F2α in the rat

Alan R. Brash, Thomas A. Baillie

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1979

Language:

english

File:

PDF, 481 KB

english, 1979

53

Identification of lipoxygenase products from arachidonic acid metabolism in stimulated murine eosinophils

John Turk, Thomas H. Rand, Richard L. Maas, John A. Lawson, Alan R. Brash, L.Jackson Roberts II, Daniel G. Colley, John A. Oates

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1983

Language:

english

File:

PDF, 1.12 MB

english, 1983

54

A secondary isotope effect in the lipoxygenase reaction

Alan R. Brash, Christiana D. Ingram, Richard L. Maas

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1986

Language:

english

File:

PDF, 652 KB

english, 1986

55

Investigation of the mechanism of biosynthesis of 8-hydroxyeicosatetraenoic acid in mouse skin

Molly A. Hughes, Alan R. Brash

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1991

Language:

english

File:

PDF, 388 KB

english, 1991

56

Incorporation of 12(S)-hydroxyeicosatetraenoic acid into the phosphatidylcholine signaling pathway

Alain B. Legrand, Jeimin Wang, Gwenn Sobo, Ian A. Blair, Alan R. Brash, John A. Oates

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1996

Language:

english

File:

PDF, 1.23 MB

english, 1996

57

Lipoxin synthesis by arachidonate 12-lipoxygenase purified from porcine leukocytes

Natsuo Ueda, Chieko Yokoyama, Shozo Yamamoto, Brian J. Fitzsimmons, Joshua Rokach, John A. Oates, Alan R. Brash

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 427 KB

english, 1987

58

Systematic synthesis of prostaglandin I2 following sustained infusion of angiotensin II in conscious dogs

Michael L. Watson, Robert J. Workman, William Herzer, Robert A. Branch, John A. Oates, Alan R. Brash

Journal:

European Journal of Pharmacology

Year:

1986

Language:

english

File:

PDF, 550 KB

english, 1986

59

Mechanism of biosynthesis of 11R- and 12R-hydroxyeicosatetraenoic acids by eggs of the sea urchin Strongylocentrotus purpuratus

Dan J. Hawkins, Alan R. Brash

Journal:

Year:

1989

Language:

english

File:

PDF, 335 KB

english, 1989

60

Structure-function features of flaxseed allene oxide synthase

Alan R. Brash, Wen-Chao Song

Journal:

Journal of Lipid Mediators and Cell Signalling

Year:

1995

Language:

english

File:

PDF, 494 KB

english, 1995

61

Identification and characterization of an arachidonate 11R-lipoxygenase

Monika Mortimer, Reet Järving, Alan R. Brash, Nigulas Samel, Ivar Järving

Journal:

Archives of Biochemistry and Biophysics

Year:

2006

Language:

english

File:

PDF, 590 KB

english, 2006

62

Human and mouse eLOX3 have distinct substrate specificities: Implications for their linkage with lipoxygenases in skin

Zheyong Yu, Claus Schneider, William E. Boeglin, Alan R. Brash

Journal:

Archives of Biochemistry and Biophysics

Year:

2006

Language:

english

File:

PDF, 547 KB

english, 2006

63

Role of the conserved distal heme asparagine of coral allene oxide synthase (Asn137) and human catalase (Asn148): Mutations affect the rate but not the essential chemistry of the enzymatic transformations

Benlian Gao, William E. Boeglin, Alan R. Brash

Journal:

Archives of Biochemistry and Biophysics

Year:

2008

Language:

english

File:

PDF, 408 KB

english, 2008

64

Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3

Zheyong Yu, Claus Schneider, William E. Boeglin, Alan R. Brash

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2005

Language:

english

File:

PDF, 611 KB

english, 2005

65

Omega-3 fatty acids are oxygenated at the n-7 carbon by the lipoxygenase domain of a fusion protein in the cyanobacterium Acaryochloris marina

Benlian Gao, William E. Boeglin, Alan R. Brash

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 538 KB

english, 2010

66

A comprehensive model of positional and stereo control in lipoxygenases

Gianguido Coffa, Claus Schneider, Alan R. Brash

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 193 KB

english, 2005

67

15-Lipoxygenase-2 (15-LOX-2) Is Expressed in Benign Prostatic Epithelium and Reduced in Prostate Adenocarcinoma

Scott B. Shappell, William E. Boeglin, Sandy J. Olson, Susan Kasper, Alan R. Brash

Journal:

The American Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 1.52 MB

english, 1999

68

Discovery of 5R-lipoxygenase activity in oocytes of the surf clam, Spisula solidissima

Takahiko Hada, Larry L. Swift, Alan R. Brash

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1997

Language:

english

File:

PDF, 158 KB

english, 1997

69

On the basis for the positional specificity and stereo specificity of lipoxygenases

Alan R Brash, Mitsuo Jisaka, William E Boeglin, Claus Schneider

Journal:

International Congress Series

Year:

2002

Language:

english

File:

PDF, 161 KB

english, 2002

70

Reduced 15-lipoxygenase-2 immunostaining in prostate adenocarcinoma: Correlation with grade and expression in high-grade prostatic intraepithelial neoplasia

Gregory S. Jack, Alan R. Brash, Sandra J. Olson, Suzanne Manning, Christopher S. Coffey, Joseph A. Smith, Jr, Scott B. Shappell

Journal:

Human Pathology

Year:

2000

Language:

english

File:

PDF, 358 KB

english, 2000

71

Corona as a Means of Minimizing the Electric Current Surge from a DC High-Voltage Terminal

Inculet, Ion I., Webster, Alan R., Brash, Stewart W., Cheung, B. S. C.

Journal:

IEEE Transactions on Industry Applications

Year:

1979

Language:

english

File:

PDF, 1.58 MB

english, 1979

72

ENDOGENOUS PROSTACYCLIN AND THROMBOXANE BIOSYNTHESIS DURING CHRONIC VITAMIN E THERAPY IN MAN

Garret A. FitzGerald, Alan R. Brash

Journal:

Annals of the New York Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 161 KB

english, 1982

73

The effect of indomethacin on the biosynthesis and metabolism of prostaglandin F2α in man

Alan R. Brash, Matthew E. Conolly

Journal:

Year:

1978

Language:

english

File:

PDF, 503 KB

english, 1978

74

Metabolism of linoleic and arachidonic acids in VX2 carcinoma tissue: Identification of monohydroxy octadecadienoic acids and monohydroxy eicosatetraenoic acids

Walter C. Hubbard, Aubrey J. Hough Jr., Alan R. Brash, J. Throck Watson, J.A. Oates

Journal:

Year:

1980

Language:

english

File:

PDF, 980 KB

english, 1980

75

Stereoselective hydrogen abstraction in leukotriene A4 synthesis by purified 5-lipoxygenase of porcine leukocytes

Natsuo Ueda, Shozo Yamamoto, John A. Oates, Alan R. Brash

Journal:

Year:

1986

Language:

english

File:

PDF, 326 KB

english, 1986

76

On the mechanism of biosynthesis of 5- and 15-series leukotrienes

Brash, Alan R., Maas, Richard L., Oates, John A.

Journal:

Journal of Allergy and Clinical Immunology

Year:

1984

Language:

english

File:

PDF, 900 KB

english, 1984

77

Activation of soluble guanylate cyclase by arachidonic acid and 15-lipoxygenase products

Rupert Gerzer, Alan R. Brash, Joel G. Hardman

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1986

Language:

english

File:

PDF, 511 KB

english, 1986

78

Straight phase separation of prostaglandin methyl esters on lipophilic gels

Alan R. Brash, Robert L. Jones

Journal:

Year:

1974

Language:

english

File:

PDF, 790 KB

english, 1974

79

Novel Transformations of HPETEs by Cytochrome P45Os

ALAN R. BRASH, MIN S. CHANG, COLIN D. FUNK, WENCHAO SONG

Journal:

Annals of the New York Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 287 KB

english, 1994

80

Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis

Thomas, Christopher P., Boeglin, William E., Garcia-Diaz, Yoel, O’Donnell, Valerie B., Brash, Alan R.

Journal:

Chemistry and Physics of Lipids

Year:

2013

Language:

english

File:

PDF, 1.16 MB

english, 2013

81

Demonstration of HNE-related Aldehyde Formation via Lipoxygenase-catalyzed Synthesis of a bis -Allylic Dihydroperoxide Intermediate

Jin, Jing, Zheng, Yuxiang, Brash, Alan R.

Journal:

Chemical Research in Toxicology

Year:

2013

Language:

english

File:

PDF, 1.32 MB

english, 2013

82

Formation of an allene oxide from (8R)-8-hydroperoxyeicosatetraenoic acid in the coral Plexaura homomalla

Journal:

Journal of the American Chemical Society

Year:

1989

Language:

english

File:

PDF, 300 KB

english, 1989

83

Formation of a cyclopropyl eicosanoid via an allene oxide in the coral Plexaura homomalla: implications for the biosynthesis of 5,6-trans-prostaglandin A2

Baertschi, Steven W., Brash, Alan R., Harris, Thomas M.

Journal:

Journal of the American Chemical Society

Year:

1989

Language:

english

File:

PDF, 398 KB

english, 1989

84

[Methods in Enzymology] Cytochrome P450, Part B Volume 272 || [28] Detection, assay, and isolation of allene oxide synthase

Year:

1996

Language:

english

File:

PDF, 479 KB

english, 1996

85

Cytochrome P450-Dependent Transformations of 15 R - and 15 S -Hydroperoxyeicosatetraenoic Acids: Stereoselective Formation of Epoxy Alcohol Products †

Chang, Min S., Boeglin, William E., Guengerich, F. Peter, Brash, Alan R.

Journal:

Year:

1996

Language:

english

File:

PDF, 602 KB

english, 1996

86

The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier

Muñoz-Garcia, Agustí, Thomas, Christopher P., Keeney, Diane S., Zheng, Yuxiang, Brash, Alan R.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2014

Language:

english

File:

PDF, 2.97 MB

english, 2014

87

Mechanism of the Rearrangement of Vinyl Allene Oxide to 2-Cyclopenten-1-one

Hess,, B. Andes, Smentek, Lidia, Brash, Alan R., Cha, Jin Kun

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 38 KB

english, 1999

88

[Part 2: Biological Sciences] || A Second Pathway of Leukotriene Biosynthesis in Porcine Leukocytes

Richard L. Maas, Alan R. Brash and John A. Oates

Journal:

Proceedings of the National Academy of Sciences

Year:

1981

Language:

english

File:

PDF, 907 KB

english, 1981

89

[Part 1: Biological Sciences] || Evidence for a Lipoxygenase Mechanism in the Biosynthesis of Epoxide and Dihydroxy Leukotrienes from 15(S)-hydroperoxyicosatetraenoic Acid by Human Platelets and Porcine Leukocytes

Richard L. Maas and Alan R. Brash

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 882 KB

english, 1983

90

Isolation and Characterization of Natural Allene Oxides: Unstable Intermediates in the Metabolism of Lipid Hydroperoxides

Alan R. Brash, Steven W. Baertschi, Christiana D. Ingram and Thomas M. Harris

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 887 KB

english, 1988

91

Frequent Clones of p53-Mutated Keratinocytes in Normal Human Skin

Alan S. Jonason, Subrahmanyam Kunala, Gary J. Price, Richard J. Restifo, Henry M. Spinelli, John A. Persing, David J. Leffell, Robert E. Tarone and Douglas E. Brash

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.17 MB

english, 1996

92

Discovery of a Second 15S-Lipoxygenase in Humans

Alan R. Brash, William E. Boeglin and Min S. Chang

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.08 MB

english, 1997

93

A 12R-Lipoxygenase in Human Skin: Mechanistic Evidence, Molecular Cloning, and Expression

William E. Boeglin, Richard B. Kim and Alan R. Brash

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.53 MB

english, 1998

94

Molecular Dynamics Simulations of Arachidonic Acid-Derived Pentadienyl Radical Intermediate Complexes with COX-1 and COX-2: Insights into Oxygenation Regio- and Stereoselectivity †

Furse, Kristina E., Pratt, Derek A., Schneider, Claus, Brash, Alan R., Porter, Ned A., Lybrand, Terry P.

Journal:

Year:

2006

Language:

english

File:

PDF, 991 KB

english, 2006

95

Identification of the Peroxidation Products of 13-Hydroxy-γ-linolenate and 15-Hydroxyarachidonate: Mechanistic Studies on the Formation of Leukotriene-like Diols †

Rector, Christopher L., Stec, Donald F., Brash, Alan R., Porter, Ned A.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 631 KB

english, 2007

96

Analysis of a specific oxygenation reaction of soybean lipoxygenase-1 with fatty acids esterified in phospholipids

Brash, Alan R., Ingram, Christiana D., Harris, Thomas M.

Journal:

Year:

1987

Language:

english

File:

PDF, 880 KB

english, 1987

97

Absolute configuration of cis-12-oxophytodienoic acid of flaxseed: implications for the mechanism of biosynthesis from the 13(S)-hydroperoxide of linolenic acid

Baertschi, Steven W., Ingram, Christiana D., Harris, Thomas M., Brash, Alan R.

Journal:

Year:

1988

Language:

english

File:

PDF, 1.18 MB

english, 1988

98

Inhibitory effects of a novel Val to Thr mutation on the distal heme of human catalase

Mashhadi, Zahra, Boeglin, William E., Brash, Alan R.

Journal:

Year:

2014

Language:

english

File:

PDF, 590 KB

english, 2014

99

A Covalent Linker Allows for Membrane Targeting of an Oxylipin Biosynthetic Complex †‡

Gilbert, Nathaniel C., Niebuhr, Marc, Tsuruta, Hiro, Bordelon, Tee, Ridderbusch, Oswin, Dassey, Adam, Brash, Alan R., Bartlett, Sue G., Newcomer, Marcia E.

Journal:

Year:

2008

Language:

english

File:

PDF, 3.06 MB

english, 2008

100

Induction of Apoptosis in Colorectal Carcinoma Cells Treated with 4-Hydroxy-2-nonenal and Structurally Related Aldehydic Products of Lipid Peroxidation

West, James D., Ji, Chuan, Duncan, Stephen T., Amarnath, Venkataraman, Schneider, Claus, Rizzo, Carmelo J., Brash, Alan R., Marnett, Lawrence J.

Journal:

Chemical Research in Toxicology

Year:

2004

Language:

english

File:

PDF, 315 KB

english, 2004