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51

Endocrine and metabolic regulation of renal drug transporters

Lindsay L. Yacovino, Lauren M. Aleksunes

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2012

Language:

english

File:

PDF, 186 KB

english, 2012

52

Decreased apoptosis during CAR-mediated hepatoprotection against lithocholic acid-induced liver injury in mice

Lisa D. Beilke, Lauren M. Aleksunes, Erik R. Olson, David G. Besselsen, Curtis D. Klaassen, Katerina Dvorak, Nathan J. Cherrington

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 1.63 MB

english, 2009

53

Regulation of Hepatic Phase II Metabolism in Pregnant Mice

Wen, X., Donepudi, A. C., Thomas, P. E., Slitt, A. L., King, R. S., Aleksunes, L. M.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2013

Language:

english

File:

PDF, 939 KB

english, 2013

54

Emerging Role of Nrf2 in Protecting Against Hepatic and Gastrointestinal Disease

Aleksunes, Lauren M., Manautou, José E.

Journal:

Toxicologic Pathology

Year:

2007

Language:

english

File:

PDF, 3.70 MB

english, 2007

55

Characterization of Peroxisome Proliferator-Activated Receptor --Independent Effects of PPAR Activators in the Rodent Liver: Di-(2-ethylhexyl) phthalate also Activates the Constitutive-Activated Receptor

Ren, H., Aleksunes, L. M., Wood, C., Vallanat, B., George, M. H., Klaassen, C. D., Corton, J. C.

Journal:

Toxicological Sciences

Year:

2010

Language:

english

File:

PDF, 662 KB

english, 2010

56

Selective Targeting of Heme Protein in Cytochrome P450 and Nitric Oxide Synthase by Diphenyleneiodonium

Szilagyi, John T., Mishin, Vladimir, Heck, Diane E., Jan, Yi-Hua, Aleksunes, Lauren M., Richardson, Jason R., Heindel, Ned D., Laskin, Debra L., Laskin, Jeffrey D.

Journal:

Toxicological Sciences

Year:

2016

Language:

english

File:

PDF, 1.19 MB

english, 2016

57

Cefoxitin Plasma and Subcutaneous Adipose Tissue Concentration in Patients Undergoing Sleeve Gastrectomy

Brunetti, Luigi, Kagan, Leonid, Forrester, Glenn, Aleksunes, Lauren M., Lin, Hongxia, Buyske, Steven, Nahass, Ronald G.

Journal:

Clinical Therapeutics

Year:

2016

Language:

english

File:

PDF, 259 KB

english, 2016

58

Drug Metabolism in Diseases || Contributors

Aleksunes, L.M.

Year:

2017

Language:

english

File:

PDF, 23 KB

english, 2017

59

Renal xenobiotic transporters are differentially expressed in mice following cisplatin treatment

Lauren M. Aleksunes, Lisa M. Augustine, George L. Scheffer, Nathan J. Cherrington, José E. Manautou

Journal:

Year:

2008

Language:

english

File:

PDF, 855 KB

english, 2008

60

Expression of Organic Anion Transporter 2 in the Human Kidney and Its Potential Role in the Tubular Secretion of Guanine-Containing Antiviral Drugs

Cheng, Y., Vapurcuyan, A., Shahidullah, M., Aleksunes, L. M., Pelis, R. M.

Journal:

Drug Metabolism and Disposition

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

61

In Vitro Transport Activity and Trafficking of MRP2/ABCC2 Polymorphic Variants

Wen, Xia, Joy, Melanie S., Aleksunes, Lauren M.

Journal:

Pharmaceutical Research

Year:

2017

Language:

english

File:

PDF, 1.88 MB

english, 2017

62

The effect of fibroblast growth factor 15 deficiency on the development of high fat diet induced non-alcoholic steatohepatitis

Schumacher, J.D., Kong, B., Pan, Y., Zhan, L., Sun, R., Aa, J., Rizzolo, D., Richardson, J.R., Chen, A., Goedken, M., Aleksunes, L.M., Laskin, D.L., Guo, G.L.

Journal:

Toxicology and Applied Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

63

Differential Regulation of Transporters in Human Placental Cells and Primary Explants in Response to Hypoxia

Aleksunes, Lauren, Gorczyca, Ludwik, Du, Jianyao, Bircsak, Kristin, Wen, Xia, Vetrano, Anna

Journal:

Year:

2019

File:

PDF, 70 KB

2019

64

Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor-E2–related factor-2 transcriptional pathway

Jonathan M. Maher, Matthew Z. Dieter, Lauren M. Aleksunes, Angela L. Slitt, Grace Guo, Yuji Tanaka, George L. Scheffer, Jefferson Y. Chan, Jose E. Manautou, Ying Chen, Timothy P. Dalton, Masayuki Yama

Journal:

Year:

2007

Language:

english

File:

PDF, 1.13 MB

english, 2007

65

Coordinated induction of Nrf2 target genes protects against iron nitrilotriacetate (FeNTA)-induced nephrotoxicity

Yuji Tanaka, Lauren M. Aleksunes, Michael J. Goedken, Chuan Chen, Scott A. Reisman, José E. Manautou, Curtis D. Klaassen

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.89 MB

english, 2008

66

IFPA Meeting 2012 Workshop Report II: Epigenetics and imprinting in the placenta, growth factors and villous trophoblast differentiation, role of the placenta in regulating fetal exposure to xenobiotics during pregnancy, infection and the placenta

Ahmed, M.S., Aleksunes, L.M., Boeuf, P., Chung, M.K., Daoud, G., Desoye, G., Díaz, P., Golos, T.G., Illsley, N.P., Kikuchi, K., Komatsu, R., Lao, T., Morales-Prieto, D.M., Nanovskaya, T., Nobuzane, T.

Journal:

Year:

2013

Language:

english

File:

PDF, 172 KB

english, 2013

67

Screening a Mouse Liver Gene Expression Compendium Identifies Modulators of the Aryl Hydrocarbon Receptor (AhR)

K. Oshida, N. Vasani, R. S. Thomas, D. Applegate, F. J. Gonzalez, L. M. Aleksunes, C. D. Klaassen, J. C. Corton

Year:

2015

Language:

english

File:

PDF, 2.55 MB

english, 2015

68

Fibroblast growth factor 15 deficiency impairs liver regeneration in mice

Kong, B., Huang, J., Zhu, Y., Li, G., Williams, J., Shen, S., Aleksunes, L. M., Richardson, J. R., Apte, U., Rudnick, D. A., Guo, G. L.

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2014

Language:

english

File:

PDF, 3.82 MB

english, 2014

69

Application of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers

Aleksunes, L. M., Yeager, R. L., Klaassen, C. D.

Journal:

Year:

2009

Language:

english

File:

PDF, 814 KB

english, 2009

70

Role of hepatic transporters in prevention of bile acid toxicity after partial hepatectomy in mice

Csanaky, I. L., Aleksunes, L. M., Tanaka, Y., Klaassen, C. D.

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2009

Language:

english

File:

PDF, 1.96 MB

english, 2009

71

Genetic regulation of drug transporters

Aleksunes, Lauren M.

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2018

Language:

english

File:

PDF, 42 KB

english, 2018

72

Identification and Characterization of Efflux Transporters That Modulate the Subtoxic Disposition of Diclofenac and Its Metabolites

Scialis, Renato J., Aleksunes, Lauren M., Csanaky, Iván L., Klaassen, Curtis D., Manautou, José E.

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 928 KB

english, 2019

73

Role of NAD(P)H:quinone oxidoreductase 1 in clofibrate-mediated hepatoprotection from acetaminophen

Jeffrey S. Moffit, Lauren M. Aleksunes, Michael J. Kardas, Angela L. Slitt, Curtis D. Klaassen, José E. Manautou

Journal:

Year:

2007

Language:

english

File:

PDF, 497 KB

english, 2007

74

Constitutive Androstane Receptor-Mediated Changes in Bile Acid Composition Contributes to Hepatoprotection from Lithocholic Acid-Induced Liver Injury in Mice

Beilke, L. D., Aleksunes, L. M., Holland, R. D., Besselsen, D. G., Beger, R. D., Klaassen, C. D., Cherrington, N. J.

Journal:

Drug Metabolism and Disposition

Year:

2009

Language:

english

File:

PDF, 604 KB

english, 2009

75

Predictive modeling of estrogen receptor agonism, antagonism, and binding activities using machine- and deep-learning approaches

Ciallella, Heather L., Russo, Daniel P., Aleksunes, Lauren M., Grimm, Fabian A., Zhu, Hao

Journal:

Laboratory Investigation

Year:

2020

File:

PDF, 1.16 MB

2020

76

Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 1

Qiuqiong Cheng, Keiko Taguchi, Lauren M. Aleksunes, José E. Manautou, Nathan J. Cherrington, Masayuki Yamamoto, Angela L. Slitt

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2011

Language:

english

File:

PDF, 258 KB

english, 2011

77

Regulation of transporter expression in mouse liver, kidney, and intestine during extrahepatic cholestasis

Angela L. Slitt, Katryn Allen, Jennifer Morrone, Lauren M. Aleksunes, Chuan Chen, Jonathan M. Maher, José E. Manautou, Nathan J. Cherrington, Curtis D. Klaassen

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2007

Language:

english

File:

PDF, 805 KB

english, 2007

78

506: Impairment of the placental barrier in response to activation of HIF-1α hypoxia-related signaling

Francois, Lissa, Bircsak, Kristin, Aleksunes, Lauren

Journal:

American Journal of Obstetrics and Gynecology

Year:

2015

Language:

english

File:

PDF, 165 KB

english, 2015

79

Localization of the placental BCRP/ ABCG2 transporter to lipid rafts: Role for cholesterol in mediating efflux activity

Szilagyi, John T., Vetrano, Anna M., Laskin, Jeffrey D., Aleksunes, Lauren M.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.82 MB

english, 2017

80

Urinary protein biomarkers of kidney injury in patients receiving cisplatin chemotherapy

George, Blessy, Joy, Melanie S, Aleksunes, Lauren M

Journal:

Experimental Biology and Medicine

Year:

2017

Language:

english

File:

PDF, 130 KB

english, 2017

81

Bardoxolone methyl modulates efflux transporter and detoxifying enzyme expression in cisplatin-induced kidney cell injury

Atilano-Roque, Amandla, Aleksunes, Lauren M., Joy, Melanie S.

Journal:

Toxicology Letters

Year:

2016

Language:

english

File:

PDF, 660 KB

english, 2016

82

Developmental regulation of the gut-liver (FGF19-CYP7A1) axis in neonates

Memon, Naureen, Griffin, Ian J., Lee, Chris W., Herdt, Aimee, Weinberger, Barry I., Hegyi, Thomas, Carayannopoulos, Mary O., Aleksunes, Lauren M., Guo, Grace L.

Journal:

Journal of Maternal-Fetal and Neonatal Medicine

Year:

2018

Language:

english

File:

PDF, 1.72 MB

english, 2018

83

Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity

Bo Kong, Iván L. Csanaky, Lauren M. Aleksunes, Meghan Patni, Qi Chen, Xiaochao Ma, Hartmut Jaeschke, Scott Weir, Melinda Broward, Curtis D. Klaassen, Grace L. Guo

Journal:

Toxicology and Applied Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

84

Hepatic and renal Bcrp transporter expression in mice treated with perfluorooctanoic acid

Eldasher, Lobna M., Wen, Xia, Little, Michael S., Bircsak, Kristin M., Yacovino, Lindsay L., Aleksunes, Lauren M.

Journal:

Year:

2013

Language:

english

File:

PDF, 797 KB

english, 2013

85

Down-Regulation of Brush Border Efflux Transporter Expression in the Kidneys of Pregnant Mice

Yacovino, L. L., Gibson, C. J., Aleksunes, L. M.

Journal:

Drug Metabolism and Disposition

Year:

2013

Language:

english

File:

PDF, 612 KB

english, 2013

86

Establishment of Metabolism and Transport Pathways in the Rodent and Human Fetal Liver

Moscovitz, Jamie, Aleksunes, Lauren

Journal:

International Journal of Molecular Sciences

Year:

2013

Language:

english

File:

PDF, 504 KB

english, 2013

87

Xenobiotic transporters and kidney injury

George, Blessy, You, Dahea, Joy, Melanie S., Aleksunes, Lauren M.

Journal:

Advanced Drug Delivery Reviews

Year:

2017

Language:

english

File:

PDF, 1.96 MB

english, 2017

88

Anandamide down-regulates placental transporter expression through CB2 receptor-mediated inhibition of cAMP synthesis

Szilagyi, John T., Composto-Wahler, Gabriella M., Joseph, Laurie B., Wang, Bingbing, Rosen, Todd, Laskin, Jeffrey D., Aleksunes, Lauren M.

Journal:

Pharmacological Research

Year:

2019

Language:

english

File:

PDF, 1.17 MB

english, 2019

89

The traditional ayurvedic medicine, Eugenia jambolana (Jamun fruit), decreases liver inflammation, injury and fibrosis during cholestasis

Ajay C. Donepudi, Lauren M. Aleksunes, Maureen V. Driscoll, Navindra P. Seeram, Angela L. Slitt

Journal:

Liver International

Year:

2012

Language:

english

File:

PDF, 882 KB

english, 2012

90

ANIT-Induced Intrahepatic Cholestasis Alters Hepatobiliary Transporter Expression via Nrf2-Dependent and Independent Signaling

Tanaka, Y., Aleksunes, L. M., Cui, Y. J., Klaassen, C. D.

Journal:

Toxicological Sciences

Year:

2009

Language:

english

File:

PDF, 926 KB

english, 2009

91

Antibacterial Spectrum of a Novel Des-Fluoro(6) Quinolone, BMS-284756

Fung-Tomc, J. C., Minassian, B., Kolek, B., Huczko, E., Aleksunes, L., Stickle, T., Washo, T., Gradelski, E., Valera, L., Bonner, D. P.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2000

Language:

english

File:

PDF, 79 KB

english, 2000

92

Repression of Hepatobiliary Transporters and Differential Regulation of Classic and Alternative Bile Acid Pathways in Mice During Pregnancy

Aleksunes, L. M., Yeager, R. L., Wen, X., Cui, J. Y., Klaassen, C. D.

Journal:

Toxicological Sciences

Year:

2012

Language:

english

File:

PDF, 17.04 MB

english, 2012

93

Inherited Disorders of Bilirubin Clearance

Memon, Naureen, Weinberger, Barry I, Hegyi, Thomas, Aleksunes, Lauren M

Journal:

Pediatric Research

Year:

2015

Language:

english

File:

PDF, 2.44 MB

english, 2015

94

Genetic and Dietary Regulation of Glyburide Efflux by the Human Placental Breast Cancer Resistance Protein Transporter

Bircsak, K. M., Gupta, V., Yuen, P. Y. S., Gorczyca, L., Weinberger, B. I., Vetrano, A. M., Aleksunes, L. M.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2016

Language:

english

File:

PDF, 844 KB

english, 2016

95

Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group

Brouwer, KLR, Aleksunes, LM, Brandys, B, Giacoia, GP, Knipp, G, Lukacova, V, Meibohm, B, Nigam, SK, Rieder, M, de Wildt, SN

Journal:

Clinical Pharmacology & Therapeutics

Year:

2015

Language:

english

File:

PDF, 334 KB

english, 2015

96

Epigenetic Regulation of MDR1 and BCRP Transporters by HDAC Inhibition

You, Dahea, Richardson, Jason R., Aleksunes, Lauren M.

Journal:

Drug Metabolism and Disposition

Year:

2020

File:

PDF, 1.02 MB

2020

97

Inhibition of Human MDR1 and BCRP Transporter ATPase Activity by Organochlorine and Pyrethroid Insecticides

Bircsak, Kristin M., Richardson, Jason R., Aleksunes, Lauren M.

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

2013

Language:

english

File:

PDF, 320 KB

english, 2013

98

Nrf2 Regulates the Sensitivity of Mouse Keratinocytes to Nitrogen Mustard via Multidrug Resistance-Associated Protein 1 (Mrp1)

Udasin, Ronald G., Wen, Xia, Bircsak, Kristin M., Aleksunes, Lauren M., Shakarjian, Michael P., Kong, Ah-Ng Tony, Heck, Diane E., Laskin, Debra L., Laskin, Jeffrey D.

Journal:

Toxicological Sciences

Year:

2015

Language:

english

File:

PDF, 650 KB

english, 2015

99

Down-regulation of the placental BCRP/ ABCG2 transporter in response to hypoxia signaling

Francois, Lissa N., Gorczyca, Ludwik, Du, Jianyao, Bircsak, Kristin M., Yen, Elizabeth, Wen, Xia, Tu, Mei-Juan, Yu, Ai-Ming, Illsley, Nicholas P., Zamudio, Stacy, Aleksunes, Lauren M.

Journal:

Year:

2017

Language:

english

File:

PDF, 980 KB

english, 2017

100

Efflux Transporters Regulate Arsenite Induced Genotoxicity in Double Negative and Double Positive T Cells

Xu, Huan, Medina, Sebastian, Lauer, Fredine T., Douillet, Christelle, Jian Liu, Ke, Hudson, Laurie G., Stýblo, Miroslav, Aleksunes, Lauren M., Burchiel, Scott W.

Journal:

Toxicological Sciences

Year:

2017

Language:

english

File:

PDF, 1.44 MB

english, 2017

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