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51

Potential antimicrobial agents for the treatment of multidrug-resistant tuberculosis

Alsaad, N., Wilffert, B., van Altena, R., de Lange, W. C. M., van der Werf, T. S., Kosterink, J. G. W., Alffenaar, J.-W. C.

Journal:

European Respiratory Journal

Year:

2014

Language:

english

File:

PDF, 532 KB

english, 2014

52

Raltegravir and rifampicin in patients with HIV and tuberculosis

Klis, Sandor, Daskapan, Alper, Akkerman, Onno W, Alffenaar, Jan-Willem, Stienstra, Ymkje

Journal:

The Lancet Infectious Diseases

Year:

2014

Language:

english

File:

PDF, 91 KB

english, 2014

53

Inflammation Is Associated with Voriconazole Trough Concentrations

van Wanrooy, M. J. P., Span, L. F. R., Rodgers, M. G. G., van den Heuvel, E. R., Uges, D. R. A., van der Werf, T. S., Kosterink, J. G. W., Alffenaar, J.-W. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2014

Language:

english

File:

PDF, 401 KB

english, 2014

54

Insufficient Fluconazole Exposure in Pediatric Cancer Patients and the Need for Therapeutic Drug Monitoring in Critically Ill Children

van der Elst, K. C. M., Pereboom, M., van den Heuvel, E. R., Kosterink, J. G. W., Scholvinck, E. H., Alffenaar, J.-W. C.

Journal:

Clinical Infectious Diseases

Year:

2014

Language:

english

File:

PDF, 157 KB

english, 2014

55

Management of patients with multidrug-resistant/extensively drug-resistant tuberculosis in Europe: a TBNET consensus statement

Lange, C., Abubakar, I., Alffenaar, J.-W. C., Bothamley, G., Caminero, J. A., Carvalho, A. C. C., Chang, K.-C., Codecasa, L., Correia, A., Crudu, V., Davies, P., Dedicoat, M., Drobniewski, F., Duarte,

Journal:

European Respiratory Journal

Year:

2014

Language:

english

File:

PDF, 1.34 MB

english, 2014

56

Pharmacokinetics of Moxifloxacin in Cerebrospinal Fluid and Plasma in Patients with Tuberculous Meningitis

Alffenaar, J. W. C., van Altena, R., Bökkerink, H. J., Luijckx, G. J., van Soolingen, D., Aarnoutse, R. E., van der Werf, T. S.

Journal:

Clinical Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 229 KB

english, 2009

57

Limited-Sampling Strategies for Anidulafungin in Critically Ill Patients

van Wanrooy, Marjolijn J. P., Proost, Johannes H., Rodgers, Michael G. G., Zijlstra, Jan G., Uges, Donald R. A., Kosterink, Jos G. W., van der Werf, Tjip S., Alffenaar, Jan-Willem C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 997 KB

english, 2015

58

Clarithromycin increases linezolid exposure in multidrug-resistant tuberculosis patients

Bolhuis, M. S., van Altena, R., van Soolingen, D., de Lange, W. C. M., Uges, D. R. A., van der Werf, T. S., Kosterink, J. G. W., Alffenaar, J.-W. C.

Journal:

European Respiratory Journal

Year:

2013

Language:

english

File:

PDF, 374 KB

english, 2013

59

Acquired Drug Resistance: We Can Do More Than We Think!

Alffenaar, J.-W. C., Gumbo, T., Aarnoutse, R. E.

Journal:

Clinical Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 53 KB

english, 2015

60

Dried blood spot analysis of creatinine with LC-MS/MS in addition to immunosuppressants analysis

Koster, Remco A., Greijdanus, Ben, Alffenaar, Jan-Willem C., Touw, Daan J.

Journal:

Analytical and Bioanalytical Chemistry

Year:

2015

Language:

english

File:

PDF, 538 KB

english, 2015

61

Dosing Ethambutol in Obese Patients

Alffenaar, J.-W., van der Werf, T., Deshpande, D., Gumbo, T.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2010

Language:

english

File:

PDF, 37 KB

english, 2010

62

Clinical Validation of the Analysis of Fluconazole in Oral Fluid in Hospitalized Children

van der Elst, K. C. M., van Alst, M., Lub-de Hooge, M. N., van Hateren, K., Kosterink, J. G. W., Alffenaar, J.-W. C., Scholvinck, E. H.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2014

Language:

english

File:

PDF, 298 KB

english, 2014

63

Breakpoints and Drug Exposure Are Inevitably Closely Linked

Alffenaar, J. W. C., Akkerman, O. W., Bolhuis, M. S., Boeree, M. J., de Lange, W. C. M., van der Werf, T. S.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 111 KB

english, 2015

64

Low but Sufficient Anidulafungin Exposure in Critically Ill Patients

van Wanrooy, M. J. P., Rodgers, M. G. G., Uges, D. R. A., Arends, J. P., Zijlstra, J. G., van der Werf, T. S., Kosterink, J. G. W., Alffenaar, J.-W. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2014

Language:

english

File:

PDF, 271 KB

english, 2014

65

Dried Blood Spot Analysis for Therapeutic Drug Monitoring of Linezolid in Patients with Multidrug-Resistant Tuberculosis

Vu, D. H., Bolhuis, M. S., Koster, R. A., Greijdanus, B., de Lange, W. C. M., van Altena, R., Brouwers, J. R. B. J., Uges, D. R. A., Alffenaar, J. W. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2012

Language:

english

File:

PDF, 186 KB

english, 2012

66

Plasma and Cerebrospinal Fluid Pharmacokinetics of Moxifloxacin in a Patient with Tuberculous Meningitis

Alffenaar, J. W. C., de Vries, P. M., Luijckx, G. J., van Soolingen, D., van der Werf, T. S., van Altena, R.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2008

Language:

english

File:

PDF, 99 KB

english, 2008

67

Strategy To Limit Sampling of Antituberculosis Drugs Instead of Determining Concentrations at Two Hours Postingestion in Relation to Treatment Response

Akkerman, O. W., van Altena, R., Bolhuis, M. S., van der Werf, T. S., Alffenaar, J.-W.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2014

Language:

english

File:

PDF, 79 KB

english, 2014

68

Evaluation of co-trimoxazole in the treatment of multidrug-resistant tuberculosis

Alsaad, N., van Altena, R., Pranger, A. D., van Soolingen, D., de Lange, W. C. M., van der Werf, T. S., Kosterink, J. G. W., Alffenaar, J.-W. C.

Journal:

European Respiratory Journal

Year:

2013

Language:

english

File:

PDF, 272 KB

english, 2013

69

Clarithromycin Significantly Increases Linezolid Serum Concentrations

Bolhuis, M. S., van Altena, R., Uges, D. R. A., van der Werf, T. S., Kosterink, J. G. W., Alffenaar, J.-W. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2010

Language:

english

File:

PDF, 188 KB

english, 2010

70

The Never Ending Struggle Against Development of Drug Resistance

Daskapan, A., Stienstra, Y., Akkerman, O. W., de Lange, W. C. M., Kosterink, J. G. W., van der Werf, T. S., Alffenaar, J.-W. C.

Journal:

Clinical Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 302 KB

english, 2015

71

Simultaneous Quantification of Anidulafungin and Caspofungin in Plasma by an Accurate and Simple Liquid Chromatography Tandem Mass-Spectrometric Method

van Wanrooy, Marjolijn J. P., Santoe, Riaaz N., van der Elst, Kim C. M., Wilmer, Carli M., van Hateren, Kai, Wessels, A. Mireille A., Greijdanus, Ben, Alffenaar, Jan-Willem C., Uges, Donald R. A.

Journal:

Therapeutic Drug Monitoring

Year:

2013

Language:

english

File:

PDF, 156 KB

english, 2013

72

Fast and Highly Selective LC-MS/MS Screening for THC and 16 Other Abused Drugs and Metabolites in Human Hair to Monitor Patients for Drug Abuse

Koster, Remco A., Alffenaar, Jan-Willem C., Greijdanus, Ben, VanDerNagel, Joanneke E. L., Uges, Donald R. A.

Journal:

Therapeutic Drug Monitoring

Year:

2014

Language:

english

File:

PDF, 148 KB

english, 2014

73

Application of Sweat Patch Screening for 16 Drugs and Metabolites Using a Fast and Highly Selective LC-MS/MS Method

Koster, Remco A., Alffenaar, Jan-Willem C., Greijdanus, Ben, VanDerNagel, Joanneke E. L., Uges, Donald R. A.

Journal:

Therapeutic Drug Monitoring

Year:

2013

Language:

english

File:

PDF, 173 KB

english, 2013

74

Adequate Design of Pharmacokinetic-Pharmacodynamic Studies Will Help Optimize Tuberculosis Treatment for the Future

Sturkenboom, Marieke G. G., Akkerman, Onno W., Bolhuis, Mathieu S., de Lange, Wiel C. M., van der Werf, Tjip S., Alffenaar, Jan-Willem C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 110 KB

english, 2015

75

Dried Blood Spot Analysis Suitable for Therapeutic Drug Monitoring of Voriconazole, Fluconazole, and Posaconazole

van der Elst, K. C. M., Span, L. F. R., van Hateren, K., Vermeulen, K. M., van der Werf, T. S., Greijdanus, B., Kosterink, J. G. W., Uges, D. R. A., Alffenaar, J.-W. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2013

Language:

english

File:

PDF, 278 KB

english, 2013

76

Determination of Moxifloxacin in Human Plasma, Plasma Ultrafiltrate, and Cerebrospinal Fluid by a Rapid and Simple Liquid Chromatography-Tandem Mass Spectrometry Method

Pranger, A. D., Alffenaar, J.-W. C., Mireille, A., Wessels, A., Greijdanus, B., Uges, D. R. A.

Journal:

Journal of Analytical Toxicology

Year:

2010

Language:

english

File:

PDF, 158 KB

english, 2010

77

Pharmacokinetics of Rifampin and Clarithromycin in Patients Treated for Mycobacterium ulcerans Infection

Alffenaar, J. W. C., Nienhuis, W. A., de Velde, F., Zuur, A. T., Wessels, A. M. A., Almeida, D., Grosset, J., Adjei, O., Uges, D. R. A., van der Werf, T. S.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2010

Language:

english

File:

PDF, 217 KB

english, 2010

78

Influence of Inflammation on Voriconazole Metabolism: TABLE 1

Encalada Ventura, M. A., Span, L. F. R., van den Heuvel, E. R., Groothuis, G. M. M., Alffenaar, J.-W. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 130 KB

english, 2015

79

Role of therapeutic drug monitoring in pulmonary infections: use and potential for expanded use of dried blood spot samples

Hofman, Susan, Bolhuis, Mathieu S, Koster, Remco A, Akkerman, Onno W, van Assen, Sander, Stove, Christophe, Alffenaar, Jan-Willem C

Journal:

Year:

2015

Language:

english

File:

PDF, 917 KB

english, 2015

80

Drug concentration in lung tissue in multidrug-resistant tuberculosis

Akkerman, O. W., van Altena, R., Klinkenberg, T., Brouwers, A. H., Bongaerts, A. H. H., van der Werf, T. S., Alffenaar, J.-W.

Journal:

European Respiratory Journal

Year:

2013

Language:

english

File:

PDF, 227 KB

english, 2013

81

Therapeutic drug monitoring: how to improve drug dosage and patient safety in tuberculosis treatment

Sotgiu, Giovanni, Alffenaar, Jan-Willem C., Centis, Rosella, D’Ambrosio, Lia, Spanevello, Antonio, Piana, Andrea, Migliori, Giovanni Battista

Journal:

International Journal of Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 575 KB

english, 2015

82

Evaluation of macrolides for possible use against multidrug-resistant Mycobacterium tuberculosis

van der Paardt, A.-F., Wilffert, B., Akkerman, O. W., de Lange, W. C. M., van Soolingen, D., Sinha, B., van der Werf, T. S., Kosterink, J. G. W., Alffenaar, J.-W. C.

Journal:

European Respiratory Journal

Year:

2015

Language:

english

File:

PDF, 347 KB

english, 2015

83

Intravenous Voriconazole after Toxic Oral Administration

Alffenaar, J. W. C., van Assen, S., de Monchy, J. G. R., Uges, D. R. A., Kosterink, J. G. W., van der Werf, T. S.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2010

Language:

english

File:

PDF, 480 KB

english, 2010

84

Susceptibility of Clinical Mycobacterium tuberculosis Isolates to a Potentially Less Toxic Derivate of Linezolid, PNU-100480

Alffenaar, J. W. C., van der Laan, T., Simons, S., van der Werf, T. S., van de Kasteele, P. J., de Neeling, H., van Soolingen, D.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2011

Language:

english

File:

PDF, 47 KB

english, 2011

85

Clinical Validation of the Analysis of Linezolid and Clarithromycin in Oral Fluid of Patients with Multidrug-Resistant Tuberculosis

Bolhuis, M. S., van Altena, R., van Hateren, K., de Lange, W. C. M., Greijdanus, B., Uges, D. R. A., Kosterink, J. G. W., van der Werf, T. S., Alffenaar, J. W. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2013

Language:

english

File:

PDF, 374 KB

english, 2013

86

Comment on: Daily 300 mg dose of linezolid for multidrug-resistant and extensively drug-resistant tuberculosis: updated analysis of 51 patients

Bolhuis, M. S., van Altena, R., Alffenaar, J.-W. C.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2012

Language:

english

File:

PDF, 83 KB

english, 2012

87

The role of therapeutic drug monitoring in individualised drug dosage and exposure measurement in tuberculosis and HIV co-infection

Daskapan, A., de Lange, W. C. M., Akkerman, O. W., Kosterink, J. G. W., van der Werf, T. S., Stienstra, Y., Alffenaar, J.-W. C.

Journal:

European Respiratory Journal

Year:

2015

Language:

english

File:

PDF, 187 KB

english, 2015

88

Linezolid: safety and efficacy monitoring

Bolhuis, M. S., Pranger, A. D., Alffenaar, J.-W. C.

Journal:

European Respiratory Journal

Year:

2012

Language:

english

File:

PDF, 120 KB

english, 2012

89

Omeprazole Significantly Reduces Posaconazole Serum Trough Level

Alffenaar, Jan‐Willem C., van Assen, Sander, van der Werf, Tjip S., Kosterink, Jos G. W., Uges, Donald R. A.

Journal:

Clinical Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 178 KB

english, 2009

90

Evaluation of moxifloxacin for the treatment of tuberculosis: 3 years of experience

Pranger, A. D., van Altena, R., Aarnoutse, R. E., van Soolingen, D., Uges, D. R. A., Kosterink, J. G. W., van der Werf, T. S., Alffenaar, J. W. C.

Journal:

European Respiratory Journal

Year:

2011

Language:

english

File:

PDF, 380 KB

english, 2011

91

The performance of five different dried blood spot cards for the analysis of six immunosuppressants

Koster, Remco A, Botma, Rixt, Greijdanus, Ben, Uges, Donald RA, Kosterink, Jos GW, Touw, Daan J, Alffenaar, Jan-Willem C

Journal:

Year:

2015

Language:

english

File:

PDF, 1.23 MB

english, 2015

92

Determination of bedaquiline in human serum using liquid chromatography tandem mass spectrometry

Alffenaar, Jan-Willem C., Bolhuis, Mathieu, van Hateren, Kai, Sturkenboom, Marieke, Akkerman, Onno, de Lange, Wiel, Greijdanus, Ben, van der Werf, Tjip, Touw, Daan

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 825 KB

english, 2015

93

Dried Blood Spot Analysis Combined With Limited Sampling Models Can Advance Therapeutic Drug Monitoring of Tuberculosis Drugs

Alffenaar, J.-W. C.

Journal:

The Journal of Infectious Diseases

Year:

2012

Language:

english

File:

PDF, 50 KB

english, 2012

94

The relation of the number of hydrogen-bond acceptors with recoveries of immunosuppressants in DBS analysis

Koster, Remco A, Alffenaar, Jan-Willem C, Botma, Rixt, Greijdanus, Ben, Uges, Donald RA, Kosterink, Jos GW, Touw, Daan J

Journal:

Year:

2015

Language:

english

File:

PDF, 952 KB

english, 2015

95

Limited sampling strategies for therapeutic drug monitoring of amikacin and kanamycin in patients with multidrug-resistant tuberculosis

Dijkstra, J.A., van Altena, R., Akkerman, O.W., de Lange, W.C.M., Proost, J.H., van der Werf, T.S., Kosterink, J.G.W., Alffenaar, J.W.C.

Journal:

International Journal of Antimicrobial Agents

Year:

2015

Language:

english

File:

PDF, 634 KB

english, 2015

96

Dried Blood Spots: A New Tool for Tuberculosis Treatment Optimization

H. Vu, D., W.C. Alffenaar, J., M. Edelbroek, P., R.B.J. Brouwers, J., R.A. Uges, D.

Journal:

Current Pharmaceutical Design

Year:

2011

Language:

english

File:

PDF, 451 KB

english, 2011

97

Pharmacokinetics of bedaquiline in cerebrospinal fluid and serum in multidrug-resistant tuberculous meningitis

Akkerman, O.W., Odish, O.F.F., Bolhuis, M.S., de Lange, W.C.M., Kremer, H.P.H., Luijckx, G.J.R., van der Werf, T.S., Alffenaar, J.W.C.

Journal:

Clinical Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 133 KB

english, 2015

98

Ertapenem in the treatment of multidrug-resistant tuberculosis: first clinical experience: TABLE 1

Tiberi, Simon, D'Ambrosio, Lia, De Lorenzo, Saverio, Viggiani, Pietro, Centis, Rosella, Sotgiu, Giovanni, Alffenaar, Jan Wilem C., Migliori, Giovanni Battista

Journal:

European Respiratory Journal

Year:

2015

Language:

english

File:

PDF, 211 KB

english, 2015

99

Quantification of co-trimoxazole in serum and plasma using MS/MS

Dijkstra, Jacob A, Alsaad, Noor SI, Hateren, Kai van, Greijdanus, Ben, Touw, Daan J, Alffenaar, Jan-Willem C

Journal:

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

100

An interlaboratory quality control programme for the measurement of tuberculosis drugs: TABLE 1

Aarnoutse, Rob E., Sturkenboom, Marieke G.G., Robijns, Karen, Harteveld, Anneke R., Greijdanus, Ben, Uges, Donald R.A., Touw, Daniel J., Alffenaar, Jan-Willem

Journal:

European Respiratory Journal

Year:

2015

Language:

english

File:

PDF, 177 KB

english, 2015