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51

Fabrication and characterisation of a novel pellicular adsorbent customised for the effective fluidised bed adsorption of protein products

Yan Sun, Andrzej W. Pacek, Alvin W. Nienow, Andrew Lyddiatt

Journal:

Biotechnology and Bioprocess Engineering

Year:

2001

Language:

english

File:

PDF, 273 KB

english, 2001

52

The application of multi-parameter flow cytometry to the study of recombinantEscherichia colibatch fermentation processes

Gareth Lewis, Ian W. Taylor, Alvin W. Nienow, Christopher J. Hewitt

Journal:

Journal of Industrial Microbiology & Biotechnology

Year:

2004

Language:

english

File:

PDF, 1002 KB

english, 2004

53

The impact of fluid mechanical stress onCorynebacterium glutamicumduring continuous cultivation in an agitated bioreactor

Saethawat Chamsartra, Christopher J. Hewitt, Alvin W. Nienow

Journal:

Biotechnology Letters

Year:

2005

Language:

english

File:

PDF, 460 KB

english, 2005

54

Studies supporting the use of mechanical mixing in large scale beer fermentations

Alvin W. Nienow, Georgina McLeod, Christopher J. Hewitt

Journal:

Biotechnology Letters

Year:

2010

Language:

english

File:

PDF, 445 KB

english, 2010

55

Expansion of human mesenchymal stem cells on microcarriers

Christopher J. Hewitt, Ken Lee, Alvin W. Nienow, Robert J. Thomas, Mark Smith, Colin R. Thomas

Journal:

Biotechnology Letters

Year:

2011

Language:

english

File:

PDF, 1.91 MB

english, 2011

56

Reactor Engineering in Large Scale Animal Cell Culture

Alvin W. Nienow

Journal:

Year:

2006

Language:

english

File:

PDF, 701 KB

english, 2006

57

Macro- and micromixing studies in an unbaffled vessel agitated by a Rushton turbine

Melissa Assirelli, Waldemar Bujalski, Archie Eaglesham, Alvin W. Nienow

Journal:

Chemical Engineering Science

Year:

2008

Language:

english

File:

PDF, 1.17 MB

english, 2008

58

Studies of High Solidity Ratio Hydrofoil Impellers for Aerated Bioreactors. 4. Comparison of Impeller Types

Caroline M. McFarlane, Alvin W. Nienow

Journal:

Biotechnology Progress

Year:

1996

Language:

english

File:

PDF, 159 KB

english, 1996

59

Studies of High Solidity Ratio Hydrofoil Impellers for Aerated Bioreactors. 3. Fluids of Enhanced Viscosity and Exhibiting Coalescence Repression

Caroline M. McFarlane, Alvin W. Nienow

Journal:

Biotechnology Progress

Year:

1996

Language:

english

File:

PDF, 160 KB

english, 1996

60

Reproducibility of Pilot Scale Xanthan Fermentations

Ashraf Amanullah, Leobardo-Carreon Serrano, Enrique Galindo, Alvin W. Nienow

Journal:

Biotechnology Progress

Year:

1996

Language:

english

File:

PDF, 535 KB

english, 1996

61

Zlokarnik Marko, ,Stirring; Theory and Practice (2001) Published by Wiley-VCH 3 527 29996 3 p.362.

Journal:

Chemical Engineering Research and Design

Year:

2002

Language:

english

File:

PDF, 57 KB

english, 2002

62

Using positron emission particle tracking (PEPT) to study the turbulent flow in a baffled vessel agitated by a Rushton turbine: Improving data treatment and validation

Fabio Chiti, Serafim Bakalis, Waldemar Bujalski, Mostafa Barigou, Archie Eaglesham, Alvin W. Nienow

Journal:

Chemical Engineering Research and Design

Year:

2011

Language:

english

File:

PDF, 1.24 MB

english, 2011

63

Mixing of Highly Viscous Simulated Xanthan Fermentation Broths with the Lightnin A-315 Impeller

Enrique Galindot, Alvin W. Nienow

Journal:

Biotechnology Progress

Year:

1992

Language:

english

File:

PDF, 1.26 MB

english, 1992

64

Studies of High Solidity Ratio Hydrofoil Impellers for Aerated Bioreactors. 2. Air—Water Studies

Caroline M. Mcfarlane, Xue -Ming Zhao, Alvin W. Nienow

Journal:

Biotechnology Progress

Year:

1995

Language:

english

File:

PDF, 1.23 MB

english, 1995

65

Studies of High Solidity Ratio Hydrofoil Impellers for Aerated Bioreactors. 1. Review

Caroline M. Mcfarlane, Alvin W. Nienow

Journal:

Biotechnology Progress

Year:

1995

Language:

english

File:

PDF, 1.48 MB

english, 1995

66

Use of multi-staining flow cytometry to characterise the physiological state of Escherichia coli W3110 in high cell density fed-batch cultures

Christopher J. Hewitt, Gerhard Nebe-Von Caron, Alvin W. Nienow, Caroline M. McFarlane

Journal:

Biotechnology and Bioengineering

Year:

1999

Language:

english

File:

PDF, 558 KB

english, 1999

67

The use of emulsification technologies to enhance rapeseed oil consumption during industrial Streptomyces rimosus fed-batch fermentations

Christopher Hewitt, Alvin Nienow

Journal:

Journal of Biotechnology

Year:

2007

Language:

english

File:

PDF, 115 KB

english, 2007

68

The use of multi-parameter flow cytometry to compare the physiological response of Escherichia coli W3110 to glucose limitation during batch, fed-batch and continuous culture cultivations

Christopher J Hewitt, Gerhard Nebe-Von Caron, Alvin W Nienow, Caroline M McFarlane

Journal:

Journal of Biotechnology

Year:

1999

Language:

english

File:

PDF, 600 KB

english, 1999

69

Large-scale expansion and exploitation of pluripotent stem cells for regenerative medicine purposes: beyond the T flask

Want, Andrew J, Nienow, Alvin W, Hewitt, Christopher J, Coopman, Karen

Journal:

Regenerative Medicine

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

70

Generation of Hydrogen Gas during the Catalytic Oxidation of Sodium Lignosulfonate to Vanillin: Initial Results

Ding, Ping, Garrett, Mark, Loe, Øystein, Nienow, Alvin W., Pacek, Andrzej W.

Journal:

Industrial & Engineering Chemistry Research

Year:

2012

Language:

english

File:

PDF, 2.55 MB

english, 2012

71

Catalytic Conversion of Sodium Lignosulfonate to Vanillin: Engineering Aspects. Part 1. Effects of Processing Conditions on Vanillin Yield and Selectivity

Pacek, Andrzej W., Ding, Ping, Garrett, Mark, Sheldrake, Gary, Nienow, Alvin W.

Journal:

Industrial & Engineering Chemistry Research

Year:

2013

Language:

english

File:

PDF, 2.09 MB

english, 2013

72

A quantitative approach for understanding small-scale human mesenchymal stem cell culture - implications for large-scale bioprocess development

Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W., Hewitt, Christopher J.

Journal:

Biotechnology Journal

Year:

2013

Language:

english

File:

PDF, 863 KB

english, 2013

73

Bubble Sizes in Agitated Water−Hydrophilic Organic Solvents for Heterogeneous Catalytic Reactions

Hu, Binjie, Nienow, Alvin W., Stitt, E. Hugh, Pacek, Andrzej W.

Journal:

Industrial & Engineering Chemistry Research

Year:

2007

Language:

english

File:

PDF, 462 KB

english, 2007

74

The translation of cell-based therapies: clinical landscape and manufacturing challenges

Heathman, Thomas RJ, Nienow, Alvin W, McCall, Mark J, Coopman, Karen, Kara, Bo, Hewitt, Christopher J

Journal:

Regenerative Medicine

Year:

2015

Language:

english

File:

PDF, 1.04 MB

english, 2015

75

Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum-free microcarrier process

Heathman, Thomas R. J., Glyn, Veronica A. M., Picken, Andrew, Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W., Kara, Bo, Hewitt, Christopher J.

Journal:

Biotechnology and Bioengineering

Year:

2015

Language:

english

File:

PDF, 1.04 MB

english, 2015

76

Characterization of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development

Heathman, Thomas R.J., Rafiq, Qasim A., Chan, Alexander K.C., Coopman, Karen, Nienow, Alvin W., Kara, Bo, Hewitt, Christopher J.

Journal:

Biochemical Engineering Journal

Year:

2015

Language:

english

File:

PDF, 1.92 MB

english, 2015

77

Serum-free process development: improving the yield and consistency of human mesenchymal stromal cell production

Heathman, Thomas R.J., Stolzing, Alexandra, Fabian, Claire, Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W., Kara, Bo, Hewitt, Christopher J.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

78

Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate

Heathman, Thomas R.J., Stolzing, Alexandra, Fabian, Claire, Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W., Kara, Bo, Hewitt, Christopher J.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.60 MB

english, 2016

79

SPIE Proceedings [SPIE Laser Anemometry: Advances and Applications--Fifth International Conference - Koningshof, Veldhoven, Netherlands (Monday 23 August 1993)] Fifth International Conference on Laser Anemometry: Advances and Applications - Hydrodynamics of a shear thinning fluid in a tank with axial flow impellers

Jaworski, Zdzislaw, Dyster, Kate N., Nienow, Alvin W., Bessem, J. M., Booij, R., Godefroy, H. W. H. E., de Groot, P. J., Prasad, K. K., de Mul, F. F. M., Nijhof, E. J.

Year:

1993

Language:

english

File:

PDF, 230 KB

english, 1993

80

Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors

Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W., Hewitt, Christopher J.

Journal:

Biotechnology Journal

Year:

2016

Language:

english

File:

PDF, 2.17 MB

english, 2016

81

Effect of gas density on power consumption in aerated vessel agitated by a Rushton turbine.

Takahashi, Koji, Nienow, Alvin W.

Journal:

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN

Year:

1992

File:

PDF, 209 KB

1992

82

Power, gas dispersion and homogenisation characteristics of Scaba SRGT and rushton turbine impellers.

Saito, Fumio, Nienow, Alvin W., Chatwin, Sidney, Moore, Iain P. T.

Journal:

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN

Year:

1992

File:

PDF, 942 KB

1992

83

Bubble Sizes and Coalescence Rates in an Aerated Vessel Agitated by a Rushton Turbine.

Takahashi, Koji, Nienow, Alvin W.

Journal:

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN

Year:

1993

File:

PDF, 6.51 MB

1993

84

Estimation of Cavern Sizes in a Shear-thinning Plastic Fluid Agitated by a Rushton Turbine Based on LDA Measurements.

Hirata, Yushi, Nienow, Alvin W., Moore, Iain P. T.

Journal:

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN

Year:

1994

File:

PDF, 2.03 MB

1994

85

Vortex cavity shape and the associated path-line of discharged bubbles in an aerated vessel agitated by a Rushton turbine.

Takahashi, Koji, Nienow, Alvin W.

Journal:

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN

Year:

1992

File:

PDF, 4.22 MB

1992

86

Engineering considerations on the use of liquid/liquid two-phase systems as a cell culture platform

Murasiewicz, Halina, Nienow, Alvin W, Hanga, Mariana P, Coopman, Karen, Hewitt, Christopher J, Pacek, Andrzej W

Journal:

Journal of Chemical Technology & Biotechnology

Year:

2017

Language:

english

File:

PDF, 2.11 MB

english, 2017

87

Scale-up agitation criteria for Trichoderma reesei fermentation

Hardy, Nicolas, Augier, Frédéric, Nienow, Alvin W., Béal, Catherine, Ben Chaabane, Fadhel

Journal:

Chemical Engineering Science

Year:

2017

Language:

english

File:

PDF, 1.71 MB

english, 2017

88

Process development of human multipotent stromal cell microcarrier culture using an automated high-throughput microbioreactor

Rafiq, Qasim A., Hanga, Mariana P., Heathman, Thomas R.J., Coopman, Karen, Nienow, Alvin W., Williams, David J., Hewitt, Christopher J.

Journal:

Biotechnology and Bioengineering

Year:

2017

Language:

english

File:

PDF, 1.51 MB

english, 2017

89

Expansion of bone marrow-derived human mesenchymal stem/stromal cells (hMSCs) using a two-phase liquid/liquid system

Hanga, Mariana P, Murasiewicz, Halina, Pacek, Andrzej W, Nienow, Alvin W, Coopman, Karen, Hewitt, Christopher J

Journal:

Journal of Chemical Technology & Biotechnology

Year:

2017

Language:

english

File:

PDF, 10.35 MB

english, 2017

90

A liquid/liquid two phase system as an economic alternative for the large-scale expansion of bone marrow-derived human mesenchymal stem/stromal cells (hMSCs)

Hanga, Mariana Petronela, Nienow, Alvin W., Coopman, Karen, Hewitt, Christopher J.

Journal:

Journal of Biotechnology

Year:

2017

Language:

english

File:

PDF, 48 KB

english, 2017

91

Qualitative and quantitative demonstration of bead-to-bead transfer with bone marrow-derived human mesenchymal stem cells on microcarriers: utilising the phenomenon to improve culture performance

Rafiq, Qasim A., Ruck, Steven, Hanga, Mariana P., Heathman, Thomas R.J., Coopman, Karen, Nienow, Alvin W., Williams, David J., Hewitt, Christopher J.

Journal:

Biochemical Engineering Journal

Year:

2017

Language:

english

File:

PDF, 1.13 MB

english, 2017

92

Mixing Time for Different Diameters of Impeller at a High Solid Concentration in an Agitated Vessel

Takenaka, Katsuhide, Takahashi, Koji, Bujalski, Waldemar, Nienow, Alvin William, Paolini, Saverio, Paglianti, Alessandro, Etchells, Arthur W.

Journal:

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN

Year:

2005

Language:

english

File:

PDF, 540 KB

english, 2005

93

Agitation and aeration of stirred-bioreactors for the microcarrier culture of human mesenchymal stem cells and potential implications for large-scale bioprocess development

Heathman, Thomas R.J., Nienow, Alvin W., Rafiq, Qasim A., Coopman, Karen, Kara, Bo, Hewitt, Christopher J.

Journal:

Biochemical Engineering Journal

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

94

Foreword: ISMIP, 1995 to 2020, THE International Mixing Conference

Nienow, Alvin W., Hirata, Yushi

Journal:

Chemical Engineering Research and Design

Year:

2018

Language:

english

File:

PDF, 211 KB

english, 2018

95

Development of a process control strategy for the serum-free microcarrier expansion of human mesenchymal stem cells towards cost-effective and commercially viable manufacturing

Heathman, Thomas R.J., Nienow, Alvin W., Rafiq, Qasim A., Coopman, Karen, Kara, Bo, Hewitt, Christopher J.

Journal:

Biochemical Engineering Journal

Year:

2018

Language:

english

File:

PDF, 1009 KB

english, 2018

96

Quantitative measurements of critical impeller speed for solid/liquid suspensions

Ye, Guichuan, Nienow, Alvin W, Alberini, Federico

Journal:

Chemical Engineering & Technology

Year:

2019

Language:

english

File:

PDF, 1.95 MB

english, 2019

97

Quantitative measurements of critical impeller speed for solid/liquid suspensions

Ye, Guichuan, Nienow, Alvin W, Alberini, Federico

Journal:

Chemical Engineering & Technology

Year:

2019

File:

PDF, 1.95 MB

2019

98

Establishing the scalable manufacture of primary human T‐cells in an automated stirred‐tank bioreactor

Costariol, Elena, Rotondi, Marco, Amini, Arman, Hewitt, Christopher J., Nienow, Alvin W., Heathman, Thomas R.J., Micheletti, Martina, Rafiq, Qasim A.

Journal:

Biotechnology and Bioengineering

Year:

2019

Language:

english

File:

PDF, 829 KB

english, 2019

99

Bioprocess development for scalable production of cultivated meat

Hanga, Mariana Petronela, Ali, Junaid, Moutsatsou, Panagiota, Raga, Fritz Anthony, Hewitt, Christopher J, Nienow, Alvin, Wall, Ivan

Journal:

Biotechnology and Bioengineering

Year:

2020

File:

PDF, 986 KB

2020

100

Demonstrating the Manufacture of Human CARâT Cells in an Automated Stirredâtank Bioreactor

Costariol, Elena, Rotondi, Marco C., Amini, Arman, Hewitt, Christopher J., Nienow, Alvin W., Heathman, Thomas R.J., Rafiq, Qasim A.

Journal:

Biotechnology Journal

Year:

2020

File:

PDF, 1.30 MB

2020