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51

Novel data analysis methods to overcome cut point challenges and enable comprehensive assessment of antidrug binding activity in confirmatory assays

Mikulskis, Alvydas, Yeung, Dave, Chen, Weiping, Mehta, Devangi, Amaravadi, Lakshmi

Journal:

Journal of Immunological Methods

Year:

2013

Language:

english

File:

PDF, 884 KB

english, 2013

52

Drug Targeting of Oncogenic Pathways in Melanoma

Fecher, Leslie A., Amaravadi, Ravi K., Schuchter, Lynn M., Flaherty, Keith T.

Journal:

Hematology/Oncology Clinics of North America

Year:

2009

Language:

english

File:

PDF, 246 KB

english, 2009

53

Phase I/II Trial of Autophagy Inhibition in Combination with Neoadjuvant Gemcitabine in High Risk Pancreatic Adenocarcinoma: Safety and Response to Treatment

Boone, B.A., Zureikat, A., Bahary, N., Bartlett, D.L., Amaravadi, R., Lotze, M.T., Zeh, H.J.

Journal:

Journal of Surgical Research

Year:

2013

Language:

english

File:

PDF, 78 KB

english, 2013

54

Daclizumab high-yield process in relapsing-remitting multiple sclerosis (SELECTION): a multicentre, randomised, double-blind extension trial

Giovannoni, Gavin, Gold, Ralf, Selmaj, Krzysztof, Havrdova, Eva, Montalban, Xavier, Radue, Ernst-Wilhelm, Stefoski, Dusan, McNeill, Manjit, Amaravadi, Lakshmi, Sweetser, Marianne, Elkins, Jacob, O'Nei

Journal:

The Lancet Neurology

Year:

2014

Language:

english

File:

PDF, 334 KB

english, 2014

55

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Anti-TWEAK Monoclonal Antibody in Patients With Rheumatoid Arthritis

Wisniacki, Nicolas, Amaravadi, Lakshmi, Galluppi, Gerald R., Zheng, Timothy S., Zhang, Ray, Kong, Jessica, Burkly, Linda C.

Journal:

Clinical Therapeutics

Year:

2013

Language:

english

File:

PDF, 347 KB

english, 2013

56

87 Inhibition of Autophagy: a Phase 1 Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Analysis of Hydroxychloroquine in Combination with the HDAC Inhibitor, Vorinostat, in Patients with Advanced Solid Tumors

Mahalingam, D., Mita, M., Sarantopoulos, J., Amaravadi, R., Davis, L., Mita, A., Curiel, T., Nawrocki, S., Carew, J.

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

57

Intelligent marketing information systems:

Amaravadi, Chandra S., Samaddar, Subhashish, Dutta, Siddhartha

Journal:

Marketing Intelligence & Planning

Year:

1995

Language:

english

File:

PDF, 80 KB

english, 1995

58

New FDA Draft Guidance on Immunogenicity

Parenky, Ashwin, Myler, Heather, Amaravadi, Lakshmi, Bechtold-Peters, Karoline, Rosenberg, Amy, Kirshner, Susan, Quarmby, Valerie

Journal:

The AAPS Journal

Year:

2014

Language:

english

File:

PDF, 144 KB

english, 2014

59

382: Identification of pathogenic virus sequences in pancreatic cancer

Amaravadi, M., Bauer, A.S., Hotz-Wagenblatt, A., Botla, S.K., Löchelt, M., Pawlita, M., Büchler, M.W., Giese, N., Hoheisel, J.D.

Journal:

European Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 66 KB

english, 2014

60

The Roles of Therapy-Induced Autophagy and Necrosis in Cancer Treatment

Amaravadi, R. K., Thompson, C. B.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 630 KB

english, 2007

61

Ocular Toxicity in BRAF Mutant Cutaneous Melanoma Patients Treated With Vemurafenib

Choe, Christina H., McArthur, Grant A., Caro, Ivor, Kempen, John H., Amaravadi, Ravi K.

Journal:

American Journal of Ophthalmology

Year:

2014

Language:

english

File:

PDF, 654 KB

english, 2014

62

In vivo maintenance of human regulatory T cells during CD25 blockade

Huss, David J., Mehta, Devangi S., Sharma, Akanksha, You, Xiaojun, Riester, Katherine A., Sheridan, James P., Amaravadi, Lakshmi S., Elkins, Jacob S., Fontenot, Jason D.

Journal:

Journal of Neuroimmunology

Year:

2014

Language:

english

File:

PDF, 50 KB

english, 2014

63

Inhibition of autophagy enhances the effects of the AKT inhibitor MK-2206 when combined with paclitaxel and carboplatin in BRAF wild-type melanoma

Rebecca, Vito W., Massaro, Renato R., Fedorenko, Inna V., Sondak, Vernon K., Anderson, Alexander R. A., Kim, Eunjung, Amaravadi, Ravi K., Maria-Engler, Silvya S., Messina, Jane L., Gibney, Geoffrey T.

Journal:

Pigment Cell & Melanoma Research

Year:

2014

Language:

english

File:

PDF, 8.51 MB

english, 2014

64

Radial Segregation Patterns in Rotating Granular Mixtures: Waviness Selection

Hill, K. M., Gioia, G., Amaravadi, D.

Journal:

Physical Review Letters

Year:

2004

Language:

english

File:

PDF, 273 KB

english, 2004

65

2013 White Paper on recent issues in bioanalysis: ‘ hybrid ’ – the best of LBA and LCMS

Stevenson, Lauren, Garofolo, Fabio, DeSilva, Binodh, Dumont, Isabelle, Martinez, Suzanne, Rocci, Mario, Amaravadi, Lakshmi, Brudny-Kloeppel, Margarete, Musuku, Adrien, Booth, Brian, Dicaire, Catherine

Journal:

Year:

2013

Language:

english

File:

PDF, 893 KB

english, 2013

66

In Vivo Maintenance of Human Regulatory T Cells during CD25 Blockade

Huss, D. J., Mehta, D. S., Sharma, A., You, X., Riester, K. A., Sheridan, J. P., Amaravadi, L. S., Elkins, J. S., Fontenot, J. D.

Journal:

The Journal of Immunology

Year:

2015

Language:

english

File:

PDF, 1.99 MB

english, 2015

67

Identification of secreted proteins that reflect autophagy dynamics within tumor cells

Kraya, Adam A., Piao, Shengfu, Xu, Xiaowei, Zhang, Gao, Herlyn, Meenhard, Gimotty, Phyllis, Levine, Beth, Amaravadi, Ravi K, Speicher, David W

Journal:

Year:

2015

Language:

english

File:

PDF, 1.88 MB

english, 2015

68

You eat what you are: autophagy inhibition as a therapeutic strategy in leukemia

Sehgal, A R, Konig, H, Johnson, D E, Tang, D, Amaravadi, R K, Boyiadzis, M, Lotze, M T

Journal:

Year:

2015

Language:

english

File:

PDF, 986 KB

english, 2015

69

Workshop Report: Crystal City V—Quantitative Bioanalytical Method Validation and Implementation: The 2013 Revised FDA Guidance

Booth, Brian, Arnold, Mark E., DeSilva, Binodh, Amaravadi, Lakshmi, Dudal, Sherri, Fluhler, Eric, Gorovits, Boris, Haidar, Sam H., Kadavil, John, Lowes, Steve, Nicholson, Robert, Rock, Marie, Skelly,

Journal:

The AAPS Journal

Year:

2015

Language:

english

File:

PDF, 261 KB

english, 2015

70

Acute pancreatitis associated with rofecoxib

Amaravadi, Ravi K., Jacobson, Brian C., Solomon, Daniel H., Fischer, Michael A.

Journal:

American Journal of Gastroenterology

Year:

2002

Language:

english

File:

PDF, 24 KB

english, 2002

71

Systemic Treatment with the Antidiabetic Drug Metformin Selectively Impairs p53-Deficient Tumor Cell Growth

Buzzai, M., Jones, R. G., Amaravadi, R. K., Lum, J. J., DeBerardinis, R. J., Zhao, F., Viollet, B., Thompson, C. B.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 591 KB

english, 2007

72

BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth

Wang, T., Xiao, M., Ge, Y., Krepler, C., Belser, E., Lopez-Coral, A., Xu, X., Zhang, G., Azuma, R., Liu, Q., Liu, R., Li, L., Amaravadi, R. K., Xu, W., Karakousis, G., Gangadhar, T. C., Schuchter, L.

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 3.09 MB

english, 2015

73

Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency

McAfee, Q., Zhang, Z., Samanta, A., Levi, S. M., Ma, X.-H., Piao, S., Lynch, J. P., Uehara, T., Sepulveda, A. R., Davis, L. E., Winkler, J. D., Amaravadi, R. K.

Journal:

Proceedings of the National Academy of Sciences

Year:

2012

Language:

english

File:

PDF, 1.34 MB

english, 2012

74

Autophagy in malignant transformation and cancer progression

Galluzzi, L., Pietrocola, F., Bravo-San Pedro, J. M., Amaravadi, R. K., Baehrecke, E. H., Cecconi, F., Codogno, P., Debnath, J., Gewirtz, D. A., Karantza, V., Kimmelman, A., Kumar, S., Levine, B., Mai

Journal:

The EMBO Journal

Year:

2015

Language:

english

File:

PDF, 9.22 MB

english, 2015

75

Combined autophagy and HDAC inhibition

Mahalingam, Devalingam, Mita, Monica, Sarantopoulos, John, Wood, Leslie, Amaravadi, Ravi K, Davis, Lisa E, Mita, Alain C, Curiel, Tyler J, Espitia, Claudia M, Nawrocki, Steffan T, Giles, Francis J, Ca

Journal:

Year:

2014

Language:

english

File:

PDF, 3.52 MB

english, 2014

76

Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma

Barnard, Rebecca A, Wittenburg, Luke A, Amaravadi, Ravi K, Gustafson, Daniel L, Thorburn, Andrew, Thamm, Douglas H

Journal:

Year:

2014

Language:

english

File:

PDF, 1.52 MB

english, 2014

77

Structural and optical properties of zinc titanates synthesized by precipitation method

BUDIGI, LOKESH, NASINA, MADHUSUDHANA RAO, SHAIK, KALEEMULLA, AMARAVADI, SIVAKUMAR

Journal:

Journal of Chemical Sciences

Year:

2015

Language:

english

File:

PDF, 2.95 MB

english, 2015

78

Physiological Role of a Multigrain Diet in Metabolic Regulations of Lipid and Antioxidant Profiles in Hypercholesteremic Rats

Vasant, Rupal A., Patel, Namrata D., Karn, Sanjay S., V. R. L. Narasimhacharya, Amaravadi

Journal:

Journal of Pharmacopuncture

Year:

2014

Language:

english

File:

PDF, 1.24 MB

english, 2014

79

Emerging strategies to effectively target autophagy in cancer

Rebecca, V W, Amaravadi, R K

Journal:

Year:

2015

Language:

english

File:

PDF, 637 KB

english, 2015

80

Tu1997 Mitochondrial-Targeted Autophagy Promotes Cancer Stem Cell Expansion in ESCC

Whelan, Kelly A., Tanaka, Koji, Kinugasa, Hideaki, Natsuizaka, Mitsuteru, Que, Jianwen, Amaravadi, Ravi K., Klein-Szanto, Andres J., Diehl, J. Alan, Rustgi, Anil K., Nakagawa, Hiroshi

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 66 KB

english, 2015

81

miR-200c/Bmi1 axis and epithelial-mesenchymal transition contribute to acquired resistance to BRAF inhibitor treatment

Liu, Shujing, Tetzlaff, Michael T., Wang, Tao, Yang, Ruifeng, Xie, Lin, Zhang, Gao, Krepler, Clemens, Xiao, Min, Beqiri, Marilda, Xu, Wei, Karakousis, Giorgos, Schuchter, Lynn, Amaravadi, Ravi K., Xu,

Journal:

Pigment Cell & Melanoma Research

Year:

2015

Language:

english

File:

PDF, 642 KB

english, 2015

82

SPIE Proceedings [SPIE SPIE's 9th Annual International Symposium on Smart Structures and Materials - San Diego, CA (Sunday 17 March 2002)] Smart Structures and Materials 2002: Modeling, Signal Processing, and Control - Two-dimensional wavelet mapping techniques for damage detection in structural systems

Amizic, Bruno, Amaravadi, Venkat, Rao, Vittal S., Derriso, Mark M., Rao, Vittal S.

Year:

2002

Language:

english

File:

PDF, 351 KB

english, 2002

83

SPIE Proceedings [SPIE SPIE's 8th Annual International Symposium on Smart Structures and Materials - Newport Beach, CA (Sunday 4 March 2001)] Smart Structures and Materials 2001: Smart Structures and Integrated Systems - Structural health monitoring using wavelet transforms

Amaravadi, Venkata K., Rao, Vittal S., Koval, Leslie R., Derriso, Mark M., Davis, L. Porter

Year:

2001

Language:

english

File:

PDF, 846 KB

english, 2001

84

Autophagy Inhibition Sensitizes Colon Cancer Cells to Antiangiogenic and Cytotoxic Therapy

Selvakumaran, M., Amaravadi, R. K., Vasilevskaya, I. A., O'Dwyer, P. J.

Journal:

Clinical Cancer Research

Year:

2013

Language:

english

File:

PDF, 1.79 MB

english, 2013

85

Long-term outcome in BRAFV600E melanoma patients treated with vemurafenib: Patterns of disease progression and clinical management of limited progression

Puzanov, Igor, Amaravadi, Ravi K., McArthur, Grant A., Flaherty, Keith T., Chapman, Paul B., Sosman, Jeffrey A., Ribas, Antoni, Shackleton, Mark, Hwu, Patrick, Chmielowski, Bartosz, Nolop, Keith B., L

Journal:

European Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 508 KB

english, 2015

86

Structural Integrity Monitoring of Bonded Composite Patch Repairs of Aging Airframes Using Wavelet Transforms

Amaravadi, K., Rao, V., Derriso, M.

Journal:

Structural Health Monitoring

Year:

2002

Language:

english

File:

PDF, 710 KB

english, 2002

87

Mouse Models Address Key Concerns Regarding Autophagy Inhibition in Cancer Therapy

Amaravadi, R., Debnath, J.

Journal:

Cancer Discovery

Year:

2014

Language:

english

File:

PDF, 495 KB

english, 2014

88

Marked, Homogeneous, and Early [18F]Fluorodeoxyglucose-Positron Emission Tomography Responses to Vemurafenib in BRAF-Mutant Advanced Melanoma

McArthur, G. A., Puzanov, I., Amaravadi, R., Ribas, A., Chapman, P., Kim, K. B., Sosman, J. A., Lee, R. J., Nolop, K., Flaherty, K. T., Callahan, J., Hicks, R. J.

Journal:

Journal of Clinical Oncology

Year:

2012

Language:

english

File:

PDF, 1.15 MB

english, 2012

89

Targeting the Cell Death-Survival Equation

Benz, E. J., Nathan, D. G., Amaravadi, R. K., Danial, N. N.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 280 KB

english, 2007

90

Punctate LC3B Expression Is a Common Feature of Solid Tumors and Associated with Proliferation, Metastasis, and Poor Outcome

Lazova, R., Camp, R. L., Klump, V., Siddiqui, S. F., Amaravadi, R. K., Pawelek, J. M.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.92 MB

english, 2012

91

[18F] Fluorodeoxyglucose Positron-Emission Tomography-CT Imaging of Carotidynia

Amaravadi, R.R., Behr, S.C., Kousoubris, P.D., Raja, S.

Journal:

American Journal of Neuroradiology

Year:

2008

Language:

english

File:

PDF, 211 KB

english, 2008

92

Phase II Trial of Temozolomide and Sorafenib in Advanced Melanoma Patients with or without Brain Metastases

Amaravadi, R. K., Schuchter, L. M., McDermott, D. F., Kramer, A., Giles, L., Gramlich, K., Carberry, M., Troxel, A. B., Letrero, R., Nathanson, K. L., Atkins, M. B., O'Dwyer, P. J., Flaherty, K. T.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 345 KB

english, 2009

93

Lys05

Amaravadi, Ravi K., Winkler, Jeffrey D.

Journal:

Year:

2012

Language:

english

File:

PDF, 554 KB

english, 2012

94

Measurements of Tumor Cell Autophagy Predict Invasiveness, Resistance to Chemotherapy, and Survival in Melanoma

Ma, X.-H., Piao, S., Wang, D., Mcafee, Q. W., Nathanson, K. L., Lum, J. J., Li, L. Z., Amaravadi, R. K.

Journal:

Clinical Cancer Research

Year:

2011

Language:

english

File:

PDF, 1.68 MB

english, 2011

95

Drosophila Forkhead Homologues Are Expressed in CD34+/HLA-DR − Primitive Human Hematopoietic Progenitors

Hromas, Robert, Klemsz, Michael, Amaravadi, Lakshmi, Hufford, Tricia, Huang, Irene, Desai, Alpana, Srour, Edward, Bruno, Edward, Hoffman, Ronald

Journal:

Leukemia and Lymphoma

Year:

1994

Language:

english

File:

PDF, 515 KB

english, 1994

96

Freeze-drying synthesis and characterisation of Na composites of ZnO, TiO2and ZnTiO3semiconductor oxides

Lokesh, Budigi, Rao, Nasina Madhusudhana, Kaleemulla, Shaik, Sivakumar, Amaravadi

Journal:

Chemical Papers

Year:

2015

Language:

english

File:

PDF, 631 KB

english, 2015

97

PUMA: A Puzzle Piece in Chloroquine’s Antimelanoma Activity

Amaravadi, Ravi K

Journal:

The Journal of Investigative Dermatology

Year:

2013

Language:

english

File:

PDF, 92 KB

english, 2013

98

Phase I/II Trial of Imatinib and Bevacizumab in Patients With Advanced Melanoma and Other Advanced Cancers

Flaherty, K. T., Hamilton, B. K., Rosen, M. A., Amaravadi, R. K., Schuchter, L. M., Gallagher, M., Chen, H., Sehgal, C., O'Dwyer, P. J.

Journal:

Year:

2015

Language:

english

File:

PDF, 847 KB

english, 2015

99

Multiple gastrointestinal polyps in patients treated with BRAF inhibitors

Amaravadi, R. K., Hamilton, K. E., Ma, X., Piao, S., Del Portillo, A., Nathanson, K. L., Carlino, M. S., Long, G. V., Puzanov, I., Xu, X., Morrissette, J. D., Tsai, K. Y., Flaherty, K. T., Sosman, J.,

Journal:

Clinical Cancer Research

Year:

2015

File:

PDF, 611 KB

2015

100

A Phase 1 Study of the SMAC-Mimetic Birinapant in Adults with Refractory Solid Tumors or Lymphoma

R. K. Amaravadi, R. J. Schilder, L. P. Martin, M. Levin, M. A. Graham, D. E. Weng, A. A. Adjei

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015