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51

Pharmacokinetic–pharmacodynamic interaction between BIA 3-202, a novel COMT inhibitor, and levodopa/benserazide

Pedro Silveira, Manuel Vaz-da-Silva, Luis Almeida, Joana Maia, Amilcar Falcão, Ana Loureiro, Leonel Torrão, Rita Machado, Lyndon Wright, Patrício Soares-da-Silva

Journal:

European Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 229 KB

english, 2003

52

Effect of nebicapone on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects

Luis Almeida, Amílcar Falcão, Manuel Vaz-da-Silva, Teresa Nunes, Ana-Teresa Santos, José-Francisco Rocha, Carla Neta, Tice Macedo, C. Fontes-Ribeiro, P. Soares-da-Silva

Journal:

European Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 150 KB

english, 2008

53

Different Epidemic Potentials of the HIV-1B and C Subtypes

Marco Salemi, Tulio de Oliveira, Marcelo A. Soares, Oliver Pybus, Ana T. Dumans, Anne-Mieke Vandamme, Amilcar Tanuri, Sharon Cassol, Walter M. Fitch

Journal:

Journal of Molecular Evolution

Year:

2005

Language:

english

File:

PDF, 254 KB

english, 2005

54

Homogenization of Climate Data: Review and New Perspectives Using Geostatistics

Ana Cristina Costa, Amílcar Soares

Journal:

Mathematical Geosciences

Year:

2009

Language:

english

File:

PDF, 458 KB

english, 2009

55

Special Issue on Geostatistics for Environmental Applications

Journal:

Mathematical Geosciences

Year:

2009

Language:

english

File:

PDF, 117 KB

english, 2009

56

Direct Sequential Co-simulation with Joint Probability Distributions

Ana Horta, Amílcar Soares

Journal:

Mathematical Geosciences

Year:

2010

Language:

english

File:

PDF, 4.94 MB

english, 2010

57

Effect of eslicarbazepine acetate on the pharmacokinetics of digoxin in healthy subjects

Manuel Vaz da Silva, Raquel Costa, Eva Soares, Joana Maia, Amílcar Falcão, Luis Almeida, Patrício Soares da Silva

Journal:

Fundamental & Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 134 KB

english, 2009

58

Sequential Indicator Simulation with Correction for Local Probabilities

Journal:

Mathematical Geosciences

Year:

1998

Language:

english

File:

PDF, 198 KB

english, 1998

59

A chiral liquid chromatography method for the simultaneous determination of oxcarbazepine, eslicarbazepine, R-licarbazepine and other new chemical derivatives BIA 2–024, BIA 2–059 and BIA 2–265, in mouse plasma and brain

Ana Fortuna, Gilberto Alves, Anabela Almeida, Bruno Lopes, Amílcar Falcão, Patrício Soares-da-Silva

Journal:

Biomedical Chromatography

Year:

2012

Language:

english

File:

PDF, 236 KB

english, 2012

60

Influence of Soil Physical Properties on Plants of the Mussununga Ecosystem, Brazil

Amilcar Walter Saporetti-Junior, Carlos Ernesto G. Reynaud Schaefer, Agostinho Lopes de Souza, Michellia Pereira Soares, Dorothy Sue Dunn Araújo, João Augusto Alves Meira-Neto

Journal:

Folia Geobotanica

Year:

2012

Language:

english

File:

PDF, 261 KB

english, 2012

61

Pharmacokinetic—pharmacodynamic interaction between nebicapone and controlled-release levodopa/benserazide: A single-center, phase I, double-blind, randomized, placebo-controlled, four-way crossover study in healthy subjects

Teresa Nunes, Rita Machado, José F. Rocha, Carlos Fernandes-Lopes, Raquel Costa, Leonel Torrão, Ana I. Loureiro, Amílcar Falcão, Manuel Vaz-da-Silva, Lyndon Wright, Luis Almeida, Patricio Soares-da-Si

Journal:

Clinical Therapeutics

Year:

2009

Language:

english

File:

PDF, 287 KB

english, 2009

62

Effect of eslicarbazepine acetate on the steady-state pharmacokinetics and pharmacodynamics of warfarin in healthy subjects during a three-stage, open-label, multiple-dose, single-period study

Manuel Vaz-da-Silva, Luis Almeida, Amilcar Falcão, Eva Soares, Joana Maia, Teresa Nunes, Patricio Soares-da-Silva

Journal:

Clinical Therapeutics

Year:

2010

Language:

english

File:

PDF, 326 KB

english, 2010

63

Pharmacokinetics and Tolerability of Etamicastat Following Single and Repeated Administration in Elderly Versus Young Healthy Male Subjects: An Open-Label, Single-Center, Parallel-Group Study

Teresa Nunes, José Francisco Rocha, Manuel Vaz-da-Silva, Amilcar Falcão, Luis Almeida, Patricio Soares-da-Silva

Journal:

Clinical Therapeutics

Year:

2011

Language:

english

File:

PDF, 2.27 MB

english, 2011

64

Stochastic environmental research risk assessment

Carla Nunes, Amilcar Soares

Journal:

Ecological Modelling

Year:

2007

Language:

english

File:

PDF, 1.28 MB

english, 2007

65

Evaluation of the permeability and P-glycoprotein efflux of carbamazepine and several derivatives across mouse small intestine by the Ussing chamber technique

Ana Fortuna, Gilberto Alves, Amílcar Falcão, Patrício Soares-da-Silva

Journal:

Year:

2012

Language:

english

File:

PDF, 462 KB

english, 2012

66

A study protocol to evaluate the relationship between outdoor air pollution and pregnancy outcomes

Manuel C Ribeiro, Maria J Pereira, Amílcar Soares, Cristina Branquinho, Sofia Augusto, Esteve Llop, Susana Fonseca, Joaquim G Nave, António B Tavares, Carlos M Dias, Ana Silva, Ismael Selemane, Joaqui

Journal:

BMC Public Health

Year:

2010

Language:

english

File:

PDF, 479 KB

english, 2010

67

Assessing Human Exposure to Polycyclic Aromatic Hydrocarbons (PAH) in a Petrochemical Region Utilizing Data from Environmental Biomonitors

Augusto, Sofia, Pereira, Maria João, Máguas, Cristina, Soares, Amílcar, Branquinho, Cristina

Journal:

Journal of Toxicology and Environmental Health Part A

Year:

2012

Language:

english

File:

PDF, 343 KB

english, 2012

68

Some ultrastructural aspects of Crithidia guilhermei n.sp. isolated from Phaenicia cuprina (Diptera: Calliphoridae)

Soares, Maurilio J., Brazil, Reginaldo P., Tanuri, Amilcar, Souza, Wanderley de

Journal:

Canadian Journal of Zoology

Year:

1986

Language:

english

File:

PDF, 1002 KB

english, 1986

69

Bioanalytical chromatographic methods for the determination of catechol-O-methyltransferase inhibitors in rodents and human samples: A review

Daniela Gonçalves, Gilberto Alves, Patrício Soares-da-Silva, Amílcar Falcão

Journal:

Analytica Chimica Acta

Year:

2012

Language:

english

File:

PDF, 1.15 MB

english, 2012

70

Data integration model to assess soil organic carbon availability

Ana Horta, Amílcar Soares

Journal:

Year:

2010

Language:

english

File:

PDF, 2.66 MB

english, 2010

71

Poster Abstract #8: Effect of Nebicapone (BIA 3-202) on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Subjects

Luis Almeida, Teresa Nunes, Manuel Vaz-da-Silva, Patricio Soares-da-Silva, Amilcar Falcão

Journal:

Neurotherapeutics

Year:

2008

Language:

english

File:

PDF, 52 KB

english, 2008

72

Poster Abstract #7: Pharmacokinetic-Pharmacodynamic Interaction Between Nebicapone (BIA 3-202) and Controlled-release Levodopa/Benserazide (Madopar HBS 125)

Luis Almeida, Jose Francisco Rocha, Carlos Lopes, Teresa Nunes, Rita Machado, Raquel Costa, Leonel Torrão, Ana-Isabel Loureiro, Manuel Vaz-da-Silva, Lyndon Wright, Patricio Soares-da-Silva, Amilcar Fa

Journal:

Neurotherapeutics

Year:

2008

Language:

english

File:

PDF, 42 KB

english, 2008

73

Improving the use of lichens as biomonitors of atmospheric metal pollution

Cristina Branquinho, Fernando Catarino, Dennis Hunther Brown, Maria João Pereira, Amilcar Soares

Journal:

Science of The Total Environment

Year:

1999

Language:

english

File:

PDF, 281 KB

english, 1999

74

In-vivo evaluation of prolonged release bilayer tablets of anti-Parkinson drugs in Göttingen minipigs

José Paulo Sousa e Silva, José S. Lobo, Maria J. Bonifácio, Rita Machado, Amílcar Falcão, Patrício Soares-da-Silva

Journal:

Journal of Pharmacy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 252 KB

english, 2011

75

Pharmacokinetics, Pharmacodynamics and Tolerability of Opicapone, a Novel Catechol-O-Methyltransferase Inhibitor, in Healthy Subjects

Luis Almeida, José Francisco Rocha, Amílcar Falcão, P. Nuno Palma, Ana I. Loureiro, Roberto Pinto, Maria João Bonifácio, Lyndon C. Wright, Teresa Nunes, Patrício Soares-da-Silva

Journal:

Clinical Pharmacokinetics

Year:

2013

Language:

english

File:

PDF, 699 KB

english, 2013

76

Opicapone: a short lived and very long acting novel catechol-O-methyltransferase inhibitor following multiple dose administration in healthy subjects

Rocha, José Francisco, Almeida, Luis, Falcão, Amílcar, Palma, P. Nuno, Loureiro, Ana I., Pinto, Roberto, Bonifácio, Maria João, Wright, Lyndon C., Nunes, Teresa, Soares-da-Silva, Patrício

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 603 KB

english, 2013

77

Single-Dose Tolerability, Pharmacokinetics, and Pharmacodynamics of Etamicastat (BIA 5-453), a New Dopamine β-Hydroxylase Inhibitor, in Healthy Subjects

Rocha, José Francisco, Vaz-Da-Silva, Manuel, Nunes, Teresa, Igreja, Bruno, Loureiro, Ana I., Bonifácio, Maria João, Wright, Lyndon C., Falcão, Amílcar, Almeida, Luis, Soares-Da-Silva, Patricio

Journal:

Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 411 KB

english, 2012

78

Single-Dose and Steady-State Pharmacokinetics of Eslicarbazepine Acetate (BIA 2-093) in Healthy Elderly and Young Subjects

Almeida, Luis, Falcão, Amílcar, Maia, Joana, Mazur, Dago, Gellert, Manfred, Soares-da-Silva, Patrício

Journal:

Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 124 KB

english, 2005

79

Pharmacokinetics, Efficacy, and Tolerability of Eslicarbazepine Acetate in Children and Adolescents With Epilepsy

Almeida, Luis, Minciu, Ioana, Nunes, Teresa, Butoianu, Nicolina, Falcão, Amilcar, Magureanu, Sandra-Adriana, Soares-da-Silva, Patrício

Journal:

Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.05 MB

english, 2008

80

Steady-state plasma and cerebrospinal fluid pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine in healthy volunteers

Teresa Nunes, José Francisco Rocha, Amílcar Falcão, Luis Almeida, Patrício Soares-da-Silva

Journal:

Year:

2012

Language:

english

File:

PDF, 322 KB

english, 2012

81

Efficacy and safety of eslicarbazepine acetate as add-on treatment in patients with focal-onset seizures: Integrated analysis of pooled data from double-blind phase III clinical studies

António Gil-Nagel, Christian Elger, Elinor Ben-Menachem, Peter Halász, José Lopes-Lima, Alberto A. Gabbai, Teresa Nunes, Amílcar Falcão, Luis Almeida, Patrício Soares da-Silva

Journal:

Year:

2012

Language:

english

File:

PDF, 389 KB

english, 2012

82

An HPLC-DAD method for the simultaneous quantification of opicapone (BIA 9-1067) and its active metabolite in human plasma

Gonçalves, Daniela, Alves, Gilberto, Fortuna, Ana, Soares-da-Silva, Patrício, Falcão, Amílcar

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2013

Language:

english

File:

PDF, 353 KB

english, 2013

83

[Quantitative Geology and Geostatistics] Geostatistics Tróia ’92 Volume 5 || Kriging Temperature in Scotland using the External Drift Method

Soares, Amilcar

Year:

1993

Language:

english

File:

PDF, 1.62 MB

english, 1993

84

Pharmacokinetic interaction study between eslicarbazepine acetate and topiramate in healthy subjects

Nunes, Teresa, Sicard, Eric, Almeida, Luis, Falcão, Amílcar, Rocha, José-Francisco, Brunet, Jean-Sebastien, Lefebvre, Marc, Soares-da-Silva, Patricio

Journal:

Current Medical Research and Opinion

Year:

2010

Language:

english

File:

PDF, 278 KB

english, 2010

85

Pharmacokinetics of Trans -resveratrol Following Repeated Administration in Healthy Elderly and Young Subjects

Nunes, Teresa, Almeida, Luis, Rocha, José-Francisco, Falcão, Amílcar, Fernandes-Lopes, Carlos, Loureiro, Ana I., Wright, Lyndon, Vaz-da-Silva, M., Soares-da-Silva, Patrício

Journal:

Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 159 KB

english, 2009

86

Geostatistical Data Integration Model for Contamination Assessment

Ana Horta, Pedro Correia, Luís Menezes Pinheiro, Amílcar Soares

Journal:

Mathematical Geosciences

Year:

2013

Language:

english

File:

PDF, 2.04 MB

english, 2013

87

[Quantitative Geology and Geostatistics] Geostatistics Tróia ’92 Volume 5 || Geostatistics: Roadblocks and Challenges

Soares, Amilcar

Year:

1993

Language:

english

File:

PDF, 1.87 MB

english, 1993

88

Pharmacokinetics, brain distribution and plasma protein binding of carbamazepine and nine derivatives: New set of data for predictive in silico ADME models

Fortuna, Ana, Alves, Gilberto, Soares-da-Silva, Patrício, Falcão, Amílcar

Journal:

Epilepsy Research

Year:

2013

Language:

english

File:

PDF, 752 KB

english, 2013

89

Multidimensional scaling for the evaluation of a geostatistical seismic elastic inversion methodology

Azevedo, Leonardo, Nunes, Ruben, Correia, Pedro, Soares, Amílcar, Guerreiro, Luis, Neto, Guenther Schwedersky

Journal:

Year:

2013

Language:

english

File:

PDF, 2.70 MB

english, 2013

90

Hybrid Model for Urban Air Pollution Forecasting: A Stochastic Spatio-Temporal Approach

Russo, Ana, Soares, Amílcar O.

Journal:

Mathematical Geosciences

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

91

Associations between outdoor air quality and birth weight: a geostatistical sequential simulation approach in Coastal Alentejo, Portugal

Castro Ribeiro, Manuel, Pinho, Pedro, Llop, Esteve, Branquinho, Cristina, Soares, Amílcar, Pereira, Maria João

Journal:

Stochastic Environmental Research and Risk Assessment

Year:

2014

Language:

english

File:

PDF, 612 KB

english, 2014

92

A new approach to soil classification mapping based on the spatial distribution of soil properties

da Silva, Alessandra Fagioli, Pereira, Maria João, Carneiro, João Daniel, Zimback, Célia Regina Lopes, Landim, Paulo Milton Barbosa, Soares, Amilcar

Journal:

Year:

2014

Language:

english

File:

PDF, 2.90 MB

english, 2014

93

Spatial modelling of soil hydraulic properties integrating different supports

Horta, Ana, Pereira, Maria João, Gonçalves, Maria, Ramos, Tiago, Soares, Amílcar

Journal:

Journal of Hydrology

Year:

2014

Language:

english

File:

PDF, 2.96 MB

english, 2014

94

FOREIGN HOSPITAL REPORTS.

Hufnagel, Andreas, Ben-Menachem, Elinor, Gabbai, Alberto A., Falcão, Amílcar, Almeida, Luis, Soares-da-Silva, Patricio

Journal:

Year:

1871

Language:

english

File:

PDF, 385 KB

english, 1871

95

Long-term safety and efficacy of eslicarbazepine acetate as adjunctive therapy in the treatment of partial-onset seizures in adults with epilepsy: Results of a 1-year open-label extension study

Hufnagel, Andreas, Ben-Menachem, Elinor, Gabbai, Alberto A., Falcão, Amílcar, Almeida, Luis, Soares-da-Silva, Patricio

Journal:

Epilepsy Research

Year:

2013

Language:

english

File:

PDF, 389 KB

english, 2013

96

Effect of eslicarbazepine acetate on the pharmacokinetics of a combined ethinylestradiol/levonorgestrel oral contraceptive in healthy women

Falcão, Amilcar, Vaz-da-Silva, Manuel, Gama, Helena, Nunes, Teresa, Almeida, Luís, Soares-da-Silva, Patrício

Journal:

Epilepsy Research

Year:

2013

Language:

english

File:

PDF, 555 KB

english, 2013

97

Effect of repeated administration of eslicarbazepine acetate on the pharmacokinetics of simvastatin in healthy subjects

Falcão, Amílcar, Pinto, Roberto, Nunes, Teresa, Soares-da-Silva, Patrício

Journal:

Epilepsy Research

Year:

2013

Language:

english

File:

PDF, 454 KB

english, 2013

98

Effect of moderate liver impairment on the pharmacokinetics of opicapone

Rocha, José Francisco, Santos, Ana, Falcão, Amílcar, Lopes, Nelson, Nunes, Teresa, Pinto, Roberto, Soares-da-Silva, Patrício

Journal:

European Journal of Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 249 KB

english, 2014

99

Effect of opicapone and entacapone upon levodopa pharmacokinetics during three daily levodopa administrations

Rocha, José-Francisco, Falcão, Amílcar, Santos, Ana, Pinto, Roberto, Lopes, Nelson, Nunes, Teresa, Wright, Lyndon C., Vaz-da-Silva, Manuel, Soares-da-Silva, Patrício

Journal:

European Journal of Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 378 KB

english, 2014

100

[Quantitative Geology and Geostatistics] geoENV VI – Geostatistics for Environmental Applications Volume 15 || Zinc Baseline Level and its Relationship with Soil Texture in Flanders, Belgium

Soares, Amílcar, Pereira, Maria João, Dimitrakopoulos, Roussos

Year:

2008

Language:

english

File:

PDF, 1.24 MB

english, 2008