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1

Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I Tax-mediated tumorigenesis

Jing Fu, Zhaoxia Qu, Pengrong Yan, Shirong Li, Xinxin Song, Chie Ishikawa, Rami I Aqeilan, Naoki Mori, Arnold B Rabson, Gutian Xiao

Journal:

Year:

2011

Language:

english

File:

PDF, 127 KB

english, 2011

2

Combined shRNA over CRISPR/cas9 as a methodology to detect off-target effects and a potential compensatory mechanism

Peretz, Liat, Besser, Elazar, Hajbi, Renana, Casden, Natania, Ziv, Dan, Kronenberg, Nechama, Gigi, Liat Ben, Sweetat, Sahar, Khawaled, Saleh, Aqeilan, Rami, Behar, Oded

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.10 MB

english, 2018

3

Animal models for chronic lymphocytic leukemia

Yuri Pekarsky, Nicola Zanesi, Rami I. Aqeilan, Carlo M. Croce

Journal:

Journal of Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 186 KB

english, 2007

4

WWOX: Its genomics, partners, and functions

Sara Del Mare, Zaidoun Salah, Rami I. Aqeilan

Journal:

Journal of Cellular Biochemistry

Year:

2009

Language:

english

File:

PDF, 196 KB

english, 2009

5

WWOX in biological control and tumorigenesis

Rami I. Aqeilan, Carlo M. Croce

Journal:

Journal of Cellular Physiology

Year:

2007

Language:

english

File:

PDF, 101 KB

english, 2007

6

Effect of IL-2-Bax, a novel interleukin-2-receptor-targeted chimeric protein, on bleomycin lung injury

Michael J. Segel, Rami Aqeilan, Keren Zilka, Haya Lorberboum-Galski, Shulamit B. Wallach-Dayan, Michael W. Conner, Thomas G. Christensen, Raphael Breuer

Journal:

International Journal of Experimental Pathology

Year:

2005

Language:

english

File:

PDF, 120 KB

english, 2005

7

Role of the WWOX gene, encompassing fragile region FRA16D, in suppression of pancreatic carcinoma cells

Shunji Nakayama, Shuho Semba, Naoko Maeda, Rami I. Aqeilan, Kay Huebner, Hiroshi Yokozaki

Journal:

Year:

2008

Language:

english

File:

PDF, 339 KB

english, 2008

8

Therapy of human pancreatic carcinoma based on suppression of HMGA1 protein synthesis in preclinical models

Trapasso, Francesco, Sarti, Manuela, Cesari, Rossano, Yendamuri, Sai, Dumon, Kristoffel R, Aqeilan, Rami I, Pentimalli, Francesca, Infante, Luisa, Alder, Hansjuerg, Abe, Nobutsugu

Journal:

Cancer Gene Therapy

Year:

2004

Language:

english

File:

PDF, 245 KB

english, 2004

9

Utilizing Chimeric Proteins for Exploring the Cellular Fate of Endogenous Proteins

Ahmi Ben-Yehudah, Rami Aqeilan, Ruth Belostotsky, Yehudith Azar, Haya Lorberboum-Galski

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 374 KB

english, 2002

10

Biophysical Basis of the Binding of WWOX Tumor Suppressor to WBP1 and WBP2 Adaptors

Caleb B. McDonald, Laura Buffa, Tomer Bar-Mag, Zaidoun Salah, Vikas Bhat, David C. Mikles, Brian J. Deegan, Kenneth L. Seldeen, Arun Malhotra, Marius Sudol, Rami I. Aqeilan, Zafar Nawaz, Amjad Farooq

Journal:

Journal of Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1.66 MB

english, 2012

11

Interleukin 2-Bax: a novel prototype of human chimeric proteins for targeted therapy

Rami Aqeilan, Shai Yarkoni, Haya Lorberboum-Galski

Journal:

Year:

1999

Language:

english

File:

PDF, 267 KB

english, 1999

12

Tcl1 as a model for lymphomagenesis

Pekarsky, Yuri, Zanesi, Nicola, Aqeilan, Rami, Croce, Carlo M.

Journal:

Hematology/Oncology Clinics of North America

Year:

2004

Language:

english

File:

PDF, 463 KB

english, 2004

13

Characterization of WWOX inactivation in murine mammary gland development

Abdeen, Suhaib K., Salah, Zaidoun, Khawaled, Saleh, Aqeilan, Rami I.

Journal:

Journal of Cellular Physiology

Year:

2013

Language:

english

File:

PDF, 5.53 MB

english, 2013

14

Epigenetic Pathways Regulating Bone Homeostasis: Potential Targeting for Intervention of Skeletal Disorders

Gordon, Jonathan A. R., Montecino, Martin A., Aqeilan, Rami I., Stein, Janet L., Stein, Gary S., Lian, Jane B.

Journal:

Current Osteoporosis Reports

Year:

2014

Language:

english

File:

PDF, 438 KB

english, 2014

15

Genetic Ablation of Ptprj , a Mouse Cancer Susceptibility Gene, Results in Normal Growth and Development and Does Not Predispose to Spontaneous Tumorigenesis

Trapasso, Francesco, Drusco, Alessandra, Costinean, Stefan, Alder, Hansjuerg, Aqeilan, Rami I., Iuliano, Rodolfo, Gaudio, Eugenio, Raso, Cinzia, Zanesi, Nicola, Croce, Carlo M., Fusco, Alfredo

Journal:

DNA and Cell Biology

Year:

2006

Language:

english

File:

PDF, 4.49 MB

english, 2006

16

Targeted Disruption of the Murine Homeodomain-Interacting Protein Kinase-2 Causes Growth Deficiency In Vivo and Cell Cycle Arrest In Vitro

Trapasso, Francesco, Aqeilan, Rami I., Iuliano, Rodolfo, Visone, Rosa, Gaudio, Eugenio, Ciuffini, Laura, Alder, Hansjuerg, Paduano, Francesco, Pierantoni, Giovanna Maria, Soddu, Silvia, Croce, Carlo M

Journal:

DNA and Cell Biology

Year:

2009

Language:

english

File:

PDF, 28.14 MB

english, 2009

17

Role of common fragile sites and corresponding genes in cancer development

Aqeilan, Rami I.

Journal:

Cellular and Molecular Life Sciences

Year:

2014

Language:

english

File:

PDF, 118 KB

english, 2014

18

Protein Inhibitor of Activated STAT3 (PIAS3) Protein Promotes SUMOylation and Nuclear Sequestration of the Intracellular Domain of ErbB4 Protein

Sundvall, Maria, Korhonen, Anna, Vaparanta, Katri, Anckar, Julius, Halkilahti, Kalle, Salah, Zaidoun, Aqeilan, Rami I., Palvimo, Jorma J., Sistonen, Lea, Elenius, Klaus

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 2.96 MB

english, 2012

19

WWOX loss activates aerobic glycolysis

Abu-Remaileh, Muhannad, Seewaldt, Victoria L, Aqeilan, Rami I

Journal:

Molecular & Cellular Oncology

Year:

2015

Language:

english

File:

PDF, 189 KB

english, 2015

20

The common fragile site FRA16D gene product WWOX: roles in tumor suppression and genomic stability

Aqeilan, Rami I., Abu-Remaileh, Muhannad, Abu-Odeh, Mohammad

Journal:

Cellular and Molecular Life Sciences

Year:

2014

Language:

english

File:

PDF, 539 KB

english, 2014

21

FHIT Suppresses Epithelial-Mesenchymal Transition (EMT) and Metastasis in Lung Cancer through Modulation of MicroRNAs

Suh, Sung-Suk, Yoo, Ji Young, Cui, Ri, Kaur, Balveen, Huebner, Kay, Lee, Taek-Kyun, Aqeilan, Rami I., Croce, Carlo M., Horwitz, Marshall S.

Journal:

Year:

2014

Language:

english

File:

PDF, 9.89 MB

english, 2014

22

Common Fragile Site Tumor Suppressor Genes and Corresponding Mouse Models of Cancer

Drusco, Alessandra, Pekarsky, Yuri, Costinean, Stefan, Antenucci, Anna, Conti, Laura, Volinia, Stefano, Aqeilan, Rami I., Huebner, Kay, Zanesi, Nicola

Journal:

Journal of Biomedicine and Biotechnology

Year:

2011

Language:

english

File:

PDF, 252 KB

english, 2011

23

NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation

Salah, Zaidoun, Cohen, Sherri, Itzhaki, Ella, Aqeilan, Rami

Journal:

Year:

2013

Language:

english

File:

PDF, 1.64 MB

english, 2013

24

Targeted Ablation of the WW Domain-Containing Oxidoreductase Tumor Suppressor Leads to Impaired Steroidogenesis

Aqeilan, Rami I., Hagan, John P., de Bruin, Alain, Rawahneh, Maysoon, Salah, Zaidoun, Gaudio, Eugenio, Siddiqui, Hasan, Volinia, Stefano, Alder, Hansjuerg, Lian, Jane B., Stein, Gary S., Croce, Carlo

Journal:

Year:

2009

Language:

english

File:

PDF, 439 KB

english, 2009

25

T538 phosphorylation, Pin-ing p63-Itch stability

Alian, Akram, Aqeilan, Rami I

Journal:

Year:

2015

Language:

english

File:

PDF, 471 KB

english, 2015

26

WWOX gene and gene product: tumor suppression through specific protein interactions

Salah, Zaidoun, Aqeilan, Rami, Huebner, Kay

Journal:

Future Oncology

Year:

2010

Language:

english

File:

PDF, 2.31 MB

english, 2010

27

Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells

Abu-Remaileh, Muhannad, Joy-Dodson, Emma, Schueler-Furman, Ora, Aqeilan, Rami I.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 1.59 MB

english, 2015

28

WWOX guards genome stability by activating ATM

Hazan, Idit, Abu-Odeh, Mohammad, Hofmann, Thomas G, Aqeilan, Rami I

Journal:

Molecular & Cellular Oncology

Year:

2015

Language:

english

File:

PDF, 1.61 MB

english, 2015

29

Genetic factors conferring metastasis in osteosarcoma

Maximov, Vadim V, Aqeilan, Rami I

Journal:

Future Oncology

Year:

2016

Language:

english

File:

PDF, 2.07 MB

english, 2016

30

Mechanism of action of interleukin-2 (IL-2)-Bax, an apoptosis-inducing chimaeric protein targeted against cells expressing the IL-2 receptor

AQEILAN, Rami, KEDAR, Rotem, BEN-YEHUDAH, Ahmi, LORBERBOUM-GALSKI, Haya

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 390 KB

english, 2003

31

Tumor Suppressor WWOX inhibits osteosarcoma metastasis by modulating RUNX2 function

Del Mare, Sara, Aqeilan, Rami I.

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1009 KB

english, 2015

32

Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells.

Trapasso, Francesco, Pichiorri, Flavia, Gaspari, Marco, Palumbo, Tiziana, Aqeilan, Rami I., Gaudio, Eugenio, Okumura, Hiroshi, Iuliano, Rodolfo, Di Leva, Giampiero, Fabbri, Muller, Birk, David E., Ras

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 52 KB

english, 2017

33

TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line

Gaudio, Eugenio, Paduano, Francesco, Pinton, Sandra, D'Agostino, Sabrina, Rocca, Roberta, Costa, Giosuè, Ngankeu, Apollinaire, Aqeilan, Rami I., Croce, Carlo M., Bertoni, Francesco, Alcaro, Stefano, T

Journal:

British Journal of Haematology

Year:

2017

Language:

english

File:

PDF, 233 KB

english, 2017

34

WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia

Abu-Remaileh, Muhannad, Khalaileh, Abed, Pikarsky, Eli, Aqeilan, Rami I.

Journal:

Cell Death and Disease

Year:

2018

Language:

english

File:

PDF, 4.24 MB

english, 2018

35

Tumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage Response

Hazan, Idit, Hofmann, Thomas G., Aqeilan, Rami I., Maizels, Nancy

Journal:

Year:

2016

Language:

english

File:

PDF, 1.41 MB

english, 2016

36

Microenvironmental Cues Determine Tumor Cell Susceptibility to Neutrophil Cytotoxicity

Gershkovitz, Maya, Fainsod-Levi, Tanya, Khawaled, Saleh, Shaul, Merav E, Sionov, Ronit Vogt, Cohen-Daniel, Leonor, Aqeilan, Rami I., Shaul, Yoav, Fridlender, Zvi G, Granot, Zvi

Journal:

Cancer Research

Year:

2018

Language:

english

File:

PDF, 4.35 MB

english, 2018

37

MicroRNAs: New Players in Multiple Myeloma

Pichiorri, Flavia, De Luca, Luciana, Aqeilan, Rami I.

Journal:

Frontiers in Genetics

Year:

2011

Language:

english

File:

PDF, 393 KB

english, 2011

38

Somatic loss of WWOX is associated with TP53 perturbation in basal-like breast cancer

Abdeen, Suhaib K., Ben-David, Uri, Shweiki, Aya, Maly, Bella, Aqeilan, Rami I.

Journal:

Cell Death and Disease

Year:

2018

Language:

english

File:

PDF, 1.63 MB

english, 2018

39

Modeling WWOX Loss of Function in vivo: What Have We Learned?

Tanna, Mayur, Aqeilan, Rami I.

Journal:

Frontiers in Oncology

Year:

2018

Language:

english

File:

PDF, 777 KB

english, 2018

40

Fhit–Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells

Druck, Teresa, Cheung, Douglas G., Park, Dongju, Trapasso, Francesco, Pichiorri, Flavia, Gaspari, Marco, Palumbo, Tiziana, Aqeilan, Rami I., Gaudio, Eugenio, Okumura, Hiroshi, Iuliano, Rodolfo, Raso,

Journal:

Cell Death and Disease

Year:

2019

File:

PDF, 1.01 MB

2019

41

Author Correction: WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia

Abu-Remaileh, Muhannad, Khalaileh, Abed, Pikarsky, Eli, Aqeilan, Rami I.

Journal:

Cell Death and Disease

Year:

2018

Language:

english

File:

PDF, 204 KB

english, 2018

42

Fhit–Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells

Druck, Teresa, Cheung, Douglas G., Park, Dongju, Trapasso, Francesco, Pichiorri, Flavia, Gaspari, Marco, Palumbo, Tiziana, Aqeilan, Rami I., Gaudio, Eugenio, Okumura, Hiroshi, Iuliano, Rodolfo, Raso,

Journal:

Cell Death and Disease

Year:

2019

Language:

english

File:

PDF, 1.01 MB

english, 2019

43

WWOX somatic ablation in skeletal muscles alters glucose metabolism

Abu-Remaileh, Muhannad, Abu-Remaileh, Monther, Akkawi, Rania, Knani, Ibrahim, Udi, Shiran, Pacold, Micheal E., Tam, Joseph, Aqeilan, Rami I.

Journal:

Molecular Metabolism

Year:

2019

Language:

english

File:

PDF, 1.58 MB

english, 2019

44

MiR‐16‐1‐3p and miR‐16‐2‐3p possess strong tumor suppressive and anti‐metastatic properties in osteosarcoma

Maximov, Vadim V., Akkawi, Rania, Khawaled, Saleh, Salah, Zaidoun, Jaber, Lina, Barhoum, Ahlam, Or, Omer, Galasso, Marco, Kurek, Kyle C., Yavin, Eylon, Aqeilan, Rami I.

Journal:

International Journal of Cancer

Year:

2019

Language:

english

File:

PDF, 5.92 MB

english, 2019

45

MiR‐16‐1‐3p and miR‐16‐2‐3p possess strong tumor suppressive and anti‐metastatic properties in osteosarcoma

Maximov, Vadim V., Akkawi, Rania, Khawaled, Saleh, Salah, Zaidoun, Jaber, Lina, Barhoum, Ahlam, Or, Omer, Galasso, Marco, Kurek, Kyle C., Yavin, Eylon, Aqeilan, Rami I.

Journal:

International Journal of Cancer

Year:

2019

File:

PDF, 5.92 MB

2019

46

Decoding the link between WWOX and p53 in aggressive breast cancer

Abdeen, Suhaib K., Aqeilan, Rami I.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.25 MB

english, 2019

47

Correction: Negative Regulation of the Hippo Pathway by E3 Ubiquitin Ligase ITCH Is Sufficient to Promote Tumorigenicity

Salah, Zaidoun, Melino, Gerry, Aqeilan, Rami I.

Journal:

Cancer Research

Year:

2019

Language:

english

File:

PDF, 157 KB

english, 2019

48

AntimiR-155 Cyclic Peptide–PNA Conjugate: Synthesis, Cellular Uptake, and Biological Activity

Soudah, Terese, Khawaled, Saleh, Aqeilan, Rami I., Yavin, Eylon

Journal:

Year:

2019

Language:

english

File:

PDF, 2.29 MB

english, 2019

49

Activation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51

Hazan, Idit, Monin, Jonathan, Bouwman, Britta A.M., Crosetto, Nicola, Aqeilan, Rami I.

Journal:

Year:

2019

File:

PDF, 3.88 MB

2019

50

Pleiotropic tumor suppressor functions of WWOX antagonize metastasis

Khawaled, Saleh, Nigita, Giovanni, Distefano, Rosario, Oster, Sara, Suh, Sung-Suk, Smith, Yoav, Khalaileh, Abed, Peng, Yong, Croce, Carlo M., Geiger, Tamar, Seewaldt, Victoria L., Aqeilan, Rami I.

Journal:

Signal Transduction and Targeted Therapy

Year:

2020

File:

PDF, 2.99 MB

2020

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