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51

Role of Acetylation and Extracellular Location of Heat Shock Protein 90 in Tumor Cell Invasion

Yang, Y., Rao, R., Shen, J., Tang, Y., Fiskus, W., Nechtman, J., Atadja, P., Bhalla, K.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 799 KB

english, 2008

52

Combination of Pan-Histone Deacetylase Inhibitor and Autophagy Inhibitor Exerts Superior Efficacy against Triple-Negative Human Breast Cancer Cells

Rao, R., Balusu, R., Fiskus, W., Mudunuru, U., Venkannagari, S., Chauhan, L., Smith, J. E., Hembruff, S. L., Ha, K., Atadja, P., Bhalla, K. N.

Journal:

Molecular Cancer Therapeutics

Year:

2012

Language:

english

File:

PDF, 1004 KB

english, 2012

53

Selective Growth Inhibition of Tumor Cells by a Novel Histone Deacetylase Inhibitor, NVP-LAQ824

Journal:

Cancer Research

Year:

2004

Language:

english

File:

PDF, 569 KB

english, 2004

54

Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells

Yu, C., Friday, B. B., Yang, L., Atadja, P., Wigle, D., Sarkaria, J., Adjei, A. A.

Journal:

Year:

2008

Language:

english

File:

PDF, 2.05 MB

english, 2008

55

Phase I Pharmacokinetic and Pharmacodynamic Study of LAQ824, a Hydroxamate Histone Deacetylase Inhibitor with a Heat Shock Protein-90 Inhibitory Profile, in Patients with Advanced Solid Tumors

de Bono, J. S., Kristeleit, R., Tolcher, A., Fong, P., Pacey, S., Karavasilis, V., Mita, M., Shaw, H., Workman, P., Kaye, S., Rowinsky, E. K., Aherne, W., Atadja, P., Scott, J. W., Patnaik, A.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 393 KB

english, 2008

56

Antitumor effect of the histone deacetylase inhibitor LAQ824 in combination with 13-cis-retinoic acid in human malignant melanoma

Kato, Y., Salumbides, B. C., Wang, X.-F., Qian, D. Z., Williams, S., Wei, Y., Sanni, T. B., Atadja, P., Pili, R.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 653 KB

english, 2007

57

The HDAC Inhibitor LBH589 Enhances the Antimyeloma Effects of the IGF-1RTK Inhibitor Picropodophyllin

Lemaire, M., Fristedt, C., Agarwal, P., Menu, E., Van Valckenborgh, E., De Bruyne, E., Osterborg, A., Atadja, P., Larsson, O., Axelson, M., Van Camp, B., Jernberg-Wiklund, H., Vanderkerken, K.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.22 MB

english, 2012

58

Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions

Rosato, R. R., Almenara, J. A., Maggio, S. C., Coe, S., Atadja, P., Dent, P., Grant, S.

Journal:

Molecular Cancer Therapeutics

Year:

2008

Language:

english

File:

PDF, 736 KB

english, 2008

59

Effect of the histone deacetylase inhibitor LBH589 against epidermal growth factor receptor dependent human lung cancer cells

Edwards, A., Li, J., Atadja, P., Bhalla, K., Haura, E. B.

Journal:

Molecular Cancer Therapeutics

Year:

2007

Language:

english

File:

PDF, 962 KB

english, 2007

60

Superior Efficacy of a Combined Epigenetic Therapy against Human Mantle Cell Lymphoma Cells

Fiskus, W., Rao, R., Balusu, R., Ganguly, S., Tao, J., Sotomayor, E., Mudunuru, U., Smith, J. E., Hembruff, S. L., Atadja, P., Marquez, V. E., Bhalla, K.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 979 KB

english, 2012

61

Combination Strategy Targeting the Hypoxia Inducible Factor-1 with Mammalian Target of Rapamycin and Histone Deacetylase Inhibitors

Verheul, H. M.W., Salumbides, B., Van Erp, K., Hammers, H., Qian, D. Z., Sanni, T., Atadja, P., Pili, R.

Journal:

Clinical Cancer Research

Year:

2008

Language:

english

File:

PDF, 606 KB

english, 2008

62

Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90: A NOVEL BASIS FOR ANTILEUKEMIA ACTIVITY OF HISTONE DEACETYLASE INHIBITORS

Bali, P., Pranpat, M., Bradner, J., Balasis, M., Fiskus, W., Guo, F., Rocha, K., Kumaraswamy, S., Boyapalle, S., Atadja, P., Seto, E., Bhalla, K.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 706 KB

english, 2005

63

Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells

Fiskus, Warren, Buckley, Kate, Rao, Rekha, Mandawat, Aditya, Yang, Yonghua, Joshi, Rajeshree, Wang, Yongchao, Balusu, Ramesh, Chen, Jianguang, Koul, Sanjay, Joshi, Atul, Upadhyay, Sunil, Atadja, Peter

Journal:

Cancer Biology & Therapy

Year:

2009

Language:

english

File:

PDF, 2.17 MB

english, 2009

64

Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy

Yang, Y., Fiskus, W., Yong, B., Atadja, P., Takahashi, Y., Pandita, T. K., Wang, H.-G., Bhalla, K. N.

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 1.05 MB

english, 2013

65

Abrogation of MAPK and Akt Signaling by AEE788 Synergistically Potentiates Histone Deacetylase Inhibitor-Induced Apoptosis through Reactive Oxygen Species Generation

Yu, C., Friday, B. B., Lai, J.-P., McCollum, A., Atadja, P., Roberts, L. R., Adjei, A. A.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 833 KB

english, 2007

66

Potentiation of the lethality of the histone deacetylase inhibitor LAQ824 by the cyclin-dependent kinase inhibitor roscovitine in human leukemia cells

Rosato, R. R., Almenara, J. A., Maggio, S. C., Atadja, P., Craig, R., Vrana, J., Dent, P., Grant, S.

Journal:

Molecular Cancer Therapeutics

Year:

2005

Language:

english

File:

PDF, 673 KB

english, 2005

67

Role of CAAT/Enhancer Binding Protein Homologous Protein in Panobinostat-Mediated Potentiation of Bortezomib-Induced Lethal Endoplasmic Reticulum Stress in Mantle Cell Lymphoma Cells

Rao, R., Nalluri, S., Fiskus, W., Savoie, A., Buckley, K. M., Ha, K., Balusu, R., Joshi, A., Coothankandaswamy, V., Tao, J., Sotomayor, E., Atadja, P., Bhalla, K. N.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 991 KB

english, 2010

68

SetDB1 modulates PRC2 activity at developmental genes independent of H3K9 trimethylation in mouse ES cells

Fei, Qi, Yang, Xiaoqin, Jiang, Hua, Wang, Qian, Yu, Yanyan, Yu, Yiling, Yi, Wei, Zhou, Shaolian, Chen, Taiping, Lu, Chris, Atadja, Peter, Liu, Xiaole Shirley, Li, En, Zhang, Yong, Shou, Jianyong

Journal:

Genome Research

Year:

2015

Language:

english

File:

PDF, 7.79 MB

english, 2015

69

Altered activity of MDR-reversing agents on KB3-1 cells transfected with Gly(185)-->Val human P-glycoprotein.

Watanabe, T, Uchiyama, N, Roninson, I B, Cohen, D, Atadja, P

Journal:

International Journal of Oncology

Year:

2000

Language:

english

File:

PDF, 1.95 MB

english, 2000

70

Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation

Zhou, Qun, Atadja, Peter, Davidson, Nancy E.

Journal:

Cancer Biology & Therapy

Year:

2007

Language:

english

File:

PDF, 891 KB

english, 2007

71

Current trends in outwitting resistance development in Candida infections through photodynamic and short peptide therapies: a strategic-shift from conventional antifungal agents

Bengyella, louis, Waikhom, Sayanika Devi, Atadja, Peter W.

Journal:

Expert Review of Anti-infective Therapy

Year:

2016

Language:

english

File:

PDF, 991 KB

english, 2016

72

Loss of Serum Response Factor Activity Is the Basis of Reduced C-FOS Expression in Aging Human Fibroblasts

Atadja, Peter W., Riabowol, Karl T.

Journal:

Canadian Journal on Aging

Year:

1996

Language:

english

File:

PDF, 2.95 MB

english, 1996

73

In vitro and in vivo rationale for the triple combination of panobinostat (LBH589) and dexamethasone with either bortezomib or lenalidomide in multiple myeloma

Ocio, E. M., Vilanova, D., Atadja, P., Maiso, P., Crusoe, E., Fernandez-Lazaro, D., Garayoa, M., San-Segundo, L., Hernandez-Iglesias, T., de Alava, E., Shao, W., Yao, Y. M., Pandiella, A., San-Miguel,

Journal:

Year:

2010

Language:

english

File:

PDF, 3.78 MB

english, 2010

74

Increased activity of p53 in senescing fibroblasts.

Atadja, P., Wong, H., Garkavtsev, I., Veillette, C., Riabowol, K.

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.88 MB

english, 1995

75

Loss of serum response element-binding activity and hyperphosphorylation of serum response factor during cellular aging.

Atadja, P W, Stringer, K F, Riabowol, K T

Journal:

Molecular and Cellular Biology

Year:

1994

Language:

english

File:

PDF, 2.84 MB

english, 1994

76

Histone deacetylase inhibitors activate NF-κB in human leukemia cells through an ATM/NEMO-related pathway.

Rosato, Roberto R., Kolla, Sarah S., Hock, Stefanie K., Almenara, Jorge A., Patel, Ankita, Amin, Sanjay, Atadja, Peter, Fisher, Paul B., Dent, Paul, Grant, Steven

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 49 KB

english, 2016

77

Histone Demethylase LSD1 Promotes Adipocyte Differentiation through Repressing Wnt Signaling

Chen, Yan, Kim, Jeesun, Zhang, Ruipeng, Yang, Xiaoqin, Zhang, Yong, Fang, Jianwu, Chen, Zhui, Teng, Lin, Chen, Xiaowei, Ge, Hui, Atadja, Peter, Li, En, Chen, Taiping, Qi, Wei

Journal:

Cell Chemical Biology

Year:

2016

Language:

english

File:

PDF, 3.85 MB

english, 2016

78

HDAC inhibitor panobinostat engages host innate immune defenses to promote the tumoricidal effects of trastuzumab in HER2+ tumors

Medon, Mikolaj, Vidacs, Eva, Vervoort, Stephin J, Li, Jason, Jenkins, Misty R, Ramsbottom, Kelly M, Trapani, Joseph A, Smyth, Mark J., Darcy, Phillip K., Atadja, Peter W, Henderson, Michael A, Johnsto

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 645 KB

english, 2017

79

A Histone Deacetylase Inhibitor LBH589 Downregulates XIAP in Mesothelioma Cell Lines Which is Likely Responsible for Increased Apoptosis With TRAIL

Symanowski, James, Vogelzang, Nicholas, Zawel, Leigh, Atadja, Peter, Pass, Harvey, Sharma, Sunil

Journal:

Journal of Thoracic Oncology

Year:

2009

Language:

english

File:

PDF, 1.35 MB

english, 2009

80

Regulation of Gene Expression and Transcription Factor Binding Activity during Cellular Aging

Meyyappan, Muthupalaniappan, Atadja, Peter W., Riabowol, Karl T.

Journal:

Year:

1996

Language:

english

File:

PDF, 1.44 MB

english, 1996

81

Soluble CD163 in intracerebral hemorrhage: biomarker for perihematomal edema

Roy-O'Reilly, Meaghan, Zhu, Liang, Atadja, Louise, Torres, Glenda, Aronowski, Jaroslaw, McCullough, Louise, Edwards, Nancy J.

Journal:

Annals of Clinical and Translational Neurology

Year:

2017

Language:

english

File:

PDF, 196 KB

english, 2017

82

Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain

Senisterra, Guillermo, Zhu, Hugh Y., Luo, Xiao, Zhang, Hailong, Xun, Guoliang, Lu, Chunliang, Xiao, Wen, Hajian, Taraneh, Loppnau, Peter, Chau, Irene, Li, Fengling, Allali-Hassani, Abdellah, Atadja, P

Journal:

Year:

2018

Language:

english

File:

PDF, 2.03 MB

english, 2018

83

Polycomb Target Genes Are Silenced in Multiple Myeloma

Kalushkova, Antonia, Fryknäs, Mårten, Lemaire, Miguel, Fristedt, Charlotte, Agarwal, Prasoon, Eriksson, Maria, Deleu, Sarah, Atadja, Peter, Österborg, Anders, Nilsson, Kenneth, Vanderkerken, Karin, Öb

Journal:

Year:

2010

Language:

english

File:

PDF, 1.91 MB

english, 2010

84

Involvement of Histone Acetylation of Sox17 and Foxa2 Promoters during Mouse Definitive Endoderm Differentiation Revealed by MicroRNA Profiling

Fu, Shijun, Fei, Qi, Jiang, Hua, Chuai, Shannon, Shi, Song, Xiong, Wen, Jiang, Lei, Lu, Chris, Atadja, Peter, Li, En, Shou, Jianyong, Cooney, Austin John

Journal:

Year:

2011

Language:

english

File:

PDF, 874 KB

english, 2011

85

Concurrent HDAC and mTORC1 Inhibition Attenuate Androgen Receptor and Hypoxia Signaling Associated with Alterations in MicroRNA Expression

Ellis, Leigh, Lehet, Kristin, Ramakrishnan, Swathi, Adelaiye, Remi, Miles, Kiersten M., Wang, Dan, Liu, Song, Atadja, Peter, Carducci, Michael A., Pili, Roberto, Schneider, Guenter

Journal:

Year:

2011

Language:

english

File:

PDF, 4.11 MB

english, 2011

86

ING1 and 5-Azacytidine Act Synergistically to Block Breast Cancer Cell Growth

Thakur, Satbir, Feng, Xiaolan, Qiao Shi, Zhong, Ganapathy, Amudha, Kumar Mishra, Manoj, Atadja, Peter, Morris, Don, Riabowol, Karl, Katz, Elad

Journal:

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

87

FXR1 regulates transcription and is required for growth of human cancer cells with TP53/FXR2 homozygous deletion

Fan, Yichao, Yue, Jiao, Xiao, Mengtao, Han-Zhang, Han, Wang, Yao Vickie, Ma, Chun, Deng, Zhilin, Li, Yingxiang, Yu, Yanyan, Wang, Xinghao, Niu, Shen, Hua, Youjia, Weng, Zhiping, Atadja, Peter, Li, En,

Journal:

Year:

2017

Language:

english

File:

PDF, 5.44 MB

english, 2017

88

Fibronectin induces the perivascular deposition of cerebrospinal fluid-derived amyloid-β in aging and after stroke

Howe, Matthew D., Atadja, Louise A., Furr, J. Weldon, Maniskas, Michael E., Zhu, Liang, McCullough, Louise D., Urayama, Akihiko

Journal:

Neurobiology of Aging

Year:

2018

Language:

english

File:

PDF, 5.06 MB

english, 2018

89

Gut Microbiota-Derived Short-Chain Fatty Acids Promote Post-Stroke Recovery in Aged Mice

Lee, Juneyoung, d'Aigle, John, Atadja, Louise, Quaicoe, Victoria, Honarpisheh, Pedram, Ganesh, Bhanu P., Hassan, Ahmad, Graf, Joerg, Petrosino, Joseph F, Putluri, Nagireddy, Zhu, Liang, Durgan, David

Journal:

Circulation Research

Year:

2020

File:

PDF, 1.67 MB

2020

90

Editor's Note: Role of CAAT/Enhancer Binding Protein Homologous Protein in Panobinostat-mediated Potentiation of Bortezomib-induced Lethal Endoplasmic Reticulum Stress in Mantle Cell Lymphoma Cells

Rao, Rekha, Nalluri, Srilatha, Fiskus, Warren, Savoie, Andrew, Buckley, Kathleen M., Ha, Kyungsoo, Balusu, Ramesh, Joshi, Atul, Coothankandaswamy, Veena, Tao, Jianguo, Sotomayor, Eduardo, Atadja, Pete

Journal:

Clinical Cancer Research

Year:

2020

File:

PDF, 177 KB

2020

91

Correction to: Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute myeloid leukemia

Salmon, Jessica M., Bots, Michael, Vidacs, Eva, Stanley, Kym L., Atadja, Peter, Zuber, Johannes, Johnstone, Ricky W.

Journal:

Clinical Epigenetics

Year:

2020

File:

PDF, 4.14 MB

2020