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1

Regulation of fungal secondary metabolism

Brakhage, Axel A.

Journal:

Nature Reviews Microbiology

Year:

2012

Language:

english

File:

PDF, 857 KB

english, 2012

2

UV-Raman spectroscopic identification of fungal spores important for respiratory diseases

Zukovskaja, Olga, Kloss, Sandra, Blango, Matthew G, Ryabchykov, Oleg, Kniemeyer, Olaf, Brakhage, Axel A., Bocklitz, Thomas Wilhelm, Cialla-May, Dana, Weber, Karina, Popp, Juergen

Journal:

Analytical Chemistry

Year:

2018

Language:

english

File:

PDF, 788 KB

english, 2018

3

Virulence determinants of the human pathogenic fungus A spergillus fumigatus protect against soil amoeba predation

Hillmann, Falk, Novohradská, Silvia, Mattern, Derek J., Forberger, Tilmann, Heinekamp, Thorsten, Westermann, Martin, Winckler, Thomas, Brakhage, Axel A.

Journal:

Environmental Microbiology

Year:

2015

Language:

english

File:

PDF, 1.46 MB

english, 2015

4

The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response

Vito Valiante, Thorsten Heinekamp, Radhika Jain, Albert Härtl, Axel A. Brakhage

Journal:

Fungal Genetics and Biology

Year:

2008

Language:

english

File:

PDF, 2.27 MB

english, 2008

5

Fungal secondary metabolites – Strategies to activate silent gene clusters

Axel A. Brakhage, Volker Schroeckh

Journal:

Fungal Genetics and Biology

Year:

2011

Language:

english

File:

PDF, 659 KB

english, 2011

6

Biosynthesis of fungal melanins and their importance for human pathogenic fungi

Kim Langfelder, Martin Streibel, Bernhard Jahn, Gerhard Haase, Axel A Brakhage

Journal:

Fungal Genetics and Biology

Year:

2003

Language:

english

File:

PDF, 222 KB

english, 2003

7

Bacterium Induces Cryptic Meroterpenoid Pathway in the Pathogenic Fungus Aspergillus fumigatus

König, Claudia C., Scherlach, Kirstin, Schroeckh, Volker, Horn, Fabian, Nietzsche, Sandor, Brakhage, Axel A., Hertweck, Christian

Journal:

Year:

2013

Language:

english

File:

PDF, 895 KB

english, 2013

8

Human and Animal Relationships || Clinical Aspects of Dermatophyte Infections

Brakhage, Axel A., Zipfel, Peter F.

Year:

2008

Language:

english

File:

PDF, 595 KB

english, 2008

9

Melanin dependent survival of Apergillus fumigatus conidia in lung epithelial cells

Amin, Shayista, Thywissen, Andreas, Heinekamp, Thorsten, Saluz, Hans Peter, Brakhage, Axel A.

Journal:

International Journal of Medical Microbiology

Year:

2014

Language:

english

File:

PDF, 2.59 MB

english, 2014

10

The novel globin protein fungoglobin is involved in low oxygen adaptation of A spergillus fumigatus

Hillmann, Falk, Linde, Jörg, Beckmann, Nicola, Cyrulies, Michael, Strassburger, Maria, Heinekamp, Thorsten, Haas, Hubertus, Guthke, Reinhard, Kniemeyer, Olaf, Brakhage, Axel A.

Journal:

Molecular Microbiology

Year:

2014

Language:

english

File:

PDF, 12.35 MB

english, 2014

11

Back cover: Immunoproteomics of Aspergillus for the development of biomarkers and immunotherapies

Kniemeyer, Olaf, Ebel, Frank, Krüger, Thomas, Bacher, Petra, Scheffold, Alexander, Luo, Ting, Strassburger, Maria, Brakhage, Axel A.

Journal:

PROTEOMICS - Clinical Applications

Year:

2016

File:

PDF, 205 KB

2016

12

Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms

Van Dijck, Patrick, Sjollema, Jelmer, Camue, Bruno P.A., Lagrou, Katrien, Berman, Judith, d’Enfert, Christophe, Andes, David R., Arendrup, Maiken C., Brakhage, Axel A., Calderone, Richard, Cantón, Emi

Journal:

Year:

2018

Language:

english

File:

PDF, 948 KB

english, 2018

13

Front Cover: Redox Proteomic Analysis Reveals Oxidative Modifications of Proteins by Increased Levels of Intracellular Reactive Oxygen Species during Hypoxia Adaptation of Aspergillus fumigatus

Shekhova, Elena, Ivanova, Lia, Krüger, Thomas, Stroe, Maria C., Macheleidt, Juliane, Kniemeyer, Olaf, Brakhage, Axel A.

Journal:

Year:

2019

File:

PDF, 27.44 MB

2019

14

Cytotoxic Pheofungins from an Engineered Fungus Impaired in Posttranslational Protein Modification

Dr. Kirstin Scherlach, Hans-Wilhelm Nützmann, Dr. Volker Schroeckh, Dr. Hans-Martin Dahse, Prof. Dr. Axel A. Brakhage, Prof. Dr. Christian Hertweck

Journal:

Angewandte Chemie

Year:

2011

Language:

english

File:

PDF, 1.56 MB

english, 2011

15

Cytotoxic Pheofungins from an Engineered Fungus Impaired in Posttranslational Protein Modification

Dr. Kirstin Scherlach, Hans-Wilhelm Nützmann, Dr. Volker Schroeckh, Dr. Hans-Martin Dahse, Prof. Dr. Axel A. Brakhage, Prof. Dr. Christian Hertweck

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 1.53 MB

english, 2011

16

Two Induced Fungal Polyketide Pathways Converge into Antiproliferative Spiroanthrones

Dr. Kirstin Scherlach, Anindita Sarkar, Dr. Volker Schroeckh, Dr. Hans-Martin Dahse, Dr. Martin Roth, Prof. Dr. Axel A. Brakhage, Dr. Uwe Horn, Prof. Dr. Christian Hertweck

Journal:

Year:

2011

Language:

english

File:

PDF, 328 KB

english, 2011

17

Evolution of β-Lactam Biosynthesis Genes and Recruitment of trans-Acting Factors

Axel A. Brakhage, Qusai Al-Abdallah, Andre Tuencher, Petra Sproete

Journal:

Year:

2005

File:

PDF, 9 KB

2005

18

ChemInform Abstract: Aspects on Evolution of Fungal β-Lactam Biosynthesis Gene Clusters and Recruitment of trans-acting Factors.

Axel A. Brakhage, Marcel Thoen, Petra Sproete, Daniel H. Scharf, Qusai Al-Abdallah, Sandra M. Wolke, Peter Hortschansky

Journal:

Year:

2010

File:

PDF, 17 KB

2010

19

Evolution of metabolic diversity

Axel Brakhage, Alfons Gierl, Thomas Hartmann, Dieter Strack

Journal:

Year:

2009

Language:

english

File:

PDF, 112 KB

english, 2009

20

PKSP-dependent reduction of phagolysosome fusion and intracellular kill of Aspergillus fumigatus conidia by human monocyte-derived macrophages

Bernhard Jahn, Kim Langfelder, Ulrike Schneider, Christine Schindel, Axel A. Brakhage

Journal:

Cellular Microbiology

Year:

2002

Language:

english

File:

PDF, 334 KB

english, 2002

21

Two-dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus

Martin Vödisch, Daniela Albrecht, Franziska Leßing, André D. Schmidt, Robert Winkler, Reinhard Guthke, Axel A. Brakhage, Olaf Kniemeyer

Journal:

Year:

2009

Language:

english

File:

PDF, 517 KB

english, 2009

22

Missing values in gel-based proteomics

Daniela Albrecht, Olaf Kniemeyer, Axel A. Brakhage, Reinhard Guthke

Journal:

Year:

2010

Language:

english

File:

PDF, 165 KB

english, 2010

23

Functional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin

Sandra Bruns, Marc Seidler, Daniela Albrecht, Stefanie Salvenmoser, Nicole Remme, Christian Hertweck, Axel A. Brakhage, Olaf Kniemeyer, Frank-Michael C. Müller

Journal:

Year:

2010

Language:

english

File:

PDF, 400 KB

english, 2010

24

Functional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin

Sandra Bruns, Marc Seidler, Daniela Albrecht, Stefanie Salvenmoser, Nicole Remme, Christian Hertweck, Axel A. Brakhage, Olaf Kniemeyer, Frank-Michael C. Müller

Journal:

PROTEOMICS - Clinical Applications

Year:

2010

Language:

english

File:

PDF, 598 KB

english, 2010

25

Analysis of the regulation of penicillin biosynthesis inAspergillus nidulansby targeted disruption of theacvAgene

Axel A. Brakhage, Philip Browne, Geoffrey Turner

Journal:

Molecular Genetics and Genomics

Year:

1994

Language:

english

File:

PDF, 820 KB

english, 1994

26

Analysis of the regulation of theAspergillus nidulanspenicillin biosynthesis geneaat(penDE), which encodes acyl coenzyme A : 6-aminopenicillanic acid acyltransferase

Olivier Litzka, Katharina Then Bergh, Axel A. Brakhage

Journal:

Molecular Genetics and Genomics

Year:

1995

Language:

english

File:

PDF, 1.57 MB

english, 1995

27

Nuclear translocation of the heterotrimeric CCAAT binding factor ofAspergillus oryzaeis dependent on two redundant localising signals in a single subunit

Hideya Goda, Takashi Nagase, Shinjiro Tanoue, Junya Sugiyama, Stefan Steidl, André Tüncher, Tetsuo Kobayashi, Norihiro Tsukagoshi, Axel A. Brakhage, Masashi Kato

Journal:

Archives of Microbiology

Year:

2005

Language:

english

File:

PDF, 389 KB

english, 2005

28

Characterisation of the laccase-encoding geneabr2of the dihydroxynaphthalene-like melanin gene cluster ofAspergillus fumigatus

Venelina Sugareva, Albert Härtl, Matthias Brock, Katrin Hübner, Manfred Rohde, Thorsten Heinekamp, Axel A. Brakhage

Journal:

Archives of Microbiology

Year:

2006

Language:

english

File:

PDF, 654 KB

english, 2006

29

The light-dependent regulator velvet A ofAspergillus nidulansacts as a repressor of the penicillin biosynthesis

Petra Spröte, Axel A. Brakhage

Journal:

Archives of Microbiology

Year:

2007

Language:

english

File:

PDF, 553 KB

english, 2007

30

TheAspergillus nidulanshomoaconitase genelysFis negatively regulated by the multimeric CCAAT-binding complex AnCF and positively regulated by GATA sites

Gerhard Weidner, Stefan Steidl, Axel A. Brakhage

Journal:

Archives of Microbiology

Year:

2001

Language:

english

File:

PDF, 284 KB

english, 2001

31

Analysis of mating-dependent transcription ofBlakeslea trisporacarotenoid biosynthesis genescarBandcarRAby quantitative real-time PCR

André D. Schmidt, Thorsten Heinekamp, Markus Matuschek, Burghard Liebmann, Claus Bollschweiler, Axel A. Brakhage

Journal:

Applied Microbiology and Biotechnology

Year:

2005

Language:

english

File:

PDF, 280 KB

english, 2005

32

Biosynthesis and function of gliotoxin inAspergillus fumigatus

Daniel H. Scharf, Thorsten Heinekamp, Nicole Remme, Peter Hortschansky, Axel A. Brakhage, Christian Hertweck

Journal:

Applied Microbiology and Biotechnology

Year:

2012

Language:

english

File:

PDF, 251 KB

english, 2012

33

A novel method used to delete a newAspergillus fumigatusABC transporter-encoding gene

Kim Langfelder, Stephanie Gattung, Axel A. Brakhage

Journal:

Current Genetics

Year:

2002

Language:

english

File:

PDF, 241 KB

english, 2002

34

Impact of the cross-pathway control on the regulation of lysine and penicillin biosynthesis inAspergillus nidulans

Silke Busch, Helge B. Bode, Axel A. Brakhage, Gerhard H. Braus

Journal:

Current Genetics

Year:

2003

Language:

english

File:

PDF, 597 KB

english, 2003

35

Optimisation of a 2-D gel electrophoresis protocol for the human-pathogenic fungusAspergillus fumigatus

Olaf Kniemeyer, Franziska Lessing, Olaf Scheibner, Christian Hertweck, Axel A. Brakhage

Journal:

Current Genetics

Year:

2006

Language:

english

File:

PDF, 540 KB

english, 2006

36

Transcriptome analysis ofAspergillus fumigatusexposed to voriconazole

Márcia Eliana da Silva Ferreira, Iran Malavazi, Marcela Savoldi, Axel A. Brakhage, Maria Helena S. Goldman, H. Stanley Kim, William C. Nierman, Gustavo H. Goldman

Journal:

Current Genetics

Year:

2006

Language:

english

File:

PDF, 1.06 MB

english, 2006

37

AoHapB, AoHapC and AoHapE, subunits of theAspergillus oryzaeCCAAT-binding complex, are functionally interchangeable with the corresponding subunits inAspergillus nidulans

Akimitsu Tanaka, Ken-ichi Kamei, Shinjiro Tanoue, Peter Papagiannopoulos, Stefan Steidl, Axel A. Brakhage, Meryl A. Davis, Michael J. Hynes, Masashi Kato, Tetsuo Kobayashi, Norihiro Tsukagoshi

Journal:

Current Genetics

Year:

2001

Language:

english

File:

PDF, 436 KB

english, 2001

38

Identification of a polyketide synthase gene (pksP) ofAspergillus fumigatusinvolved in conidial pigment biosynthesis and virulence

K. Langfelder, Bernhard Jahn, Heike Gehringer, Axel Schmidt, Gerhard Wanner, Axel A. Brakhage

Journal:

Medical Microbiology and Immunology

Year:

1998

Language:

english

File:

PDF, 809 KB

english, 1998

39

Molecular characterization of theAspergillus fumigatus NCS-1homologue, NcsA

André Oliveira Mota Júnior, Iran Malavazi, Frederico Marianetti Soriani, Thorsten Heinekamp, Ilse Jacobsen, Axel A. Brakhage, Marcela Savoldi, Maria Helena S. Goldman, Márcia Eliana da Silva Ferreira,

Journal:

Molecular Genetics and Genomics

Year:

2008

Language:

english

File:

PDF, 674 KB

english, 2008

40

Evolution of β-lactam biosynthesis genes and recruitment of trans-acting factors

Axel A. Brakhage, Qusai Al-Abdallah, André Tüncher, Petra Spröte

Journal:

Year:

2005

Language:

english

File:

PDF, 438 KB

english, 2005

41

Aspects on evolution of fungal β-lactam biosynthesis gene clusters and recruitment of trans-acting factors

Axel A. Brakhage, Marcel Thön, Petra Spröte, Daniel H. Scharf, Qusai Al-Abdallah, Sandra M. Wolke, Peter Hortschansky

Journal:

Year:

2009

Language:

english

File:

PDF, 2.07 MB

english, 2009

42

Aminoacyl-tRNA synthetase gene regulation in Bacillus subtilis: induction, repression and growth-rate regulation

Harald Putzer, Soumaya Laalami, Axel A. Brakhage, Ciarán Condon, Marianne Grunberg-Manago

Journal:

Molecular Microbiology

Year:

1995

Language:

english

File:

PDF, 2.63 MB

english, 1995

43

A basic-region helix–loop–helix protein-encoding gene (devR) involved in the development of Aspergillus nidulans

André Tüncher, Hans Reinke, Goran Martic, Maria Louise Caruso, Axel A. Brakhage

Journal:

Molecular Microbiology

Year:

2004

Language:

english

File:

PDF, 326 KB

english, 2004

44

Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model

Claudio Kupfahl, Thorsten Heinekamp, Gernot Geginat, Thomas Ruppert, Albert Härtl, Herbert Hof, Axel A. Brakhage

Journal:

Molecular Microbiology

Year:

2006

Language:

english

File:

PDF, 330 KB

english, 2006

45

Identification of the novel penicillin biosynthesis gene aatB of Aspergillus nidulans and its putative evolutionary relationship to this fungal secondary metabolism gene cluster

Petra Spröte, Michael J. Hynes, Peter Hortschansky, Ekaterina Shelest, Daniel H. Scharf, Sandra M. Wolke, Axel A. Brakhage

Journal:

Molecular Microbiology

Year:

2008

Language:

english

File:

PDF, 1.01 MB

english, 2008

46

SreA-mediated iron regulation in Aspergillus fumigatus

Markus Schrettl, H. Stanley Kim, Martin Eisendle, Claudia Kragl, William C. Nierman, Thorsten Heinekamp, Ernst R. Werner, Ilse Jacobsen, Paul Illmer, Hyojeong Yi, Axel A. Brakhage, Hubertus Haas

Journal:

Molecular Microbiology

Year:

2008

Language:

english

File:

PDF, 569 KB

english, 2008

47

The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus

Radhika Jain, Vito Valiante, Nicole Remme, Teresa Docimo, Thorsten Heinekamp, Christian Hertweck, Jonathan Gershenzon, Hubertus Haas, Axel A. Brakhage

Journal:

Molecular Microbiology

Year:

2011

Language:

english

File:

PDF, 1.21 MB

english, 2011

48

Phagocytosis of Aspergillus fumigatus conidia by murine macrophages involves recognition by the dectin-1 beta-glucan receptor and Toll-like receptor 2

Kathrin Luther, Antonella Torosantucci, Axel A. Brakhage, Jürgen Heesemann, Frank Ebel

Journal:

Cellular Microbiology

Year:

2007

Language:

english

File:

PDF, 750 KB

english, 2007

49

Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis

Oumaïma Ibrahim-Granet, Marc Dubourdeau, Jean-Paul Latgé, Patrick Ave, Michel Huerre, Axel A. Brakhage, Matthias Brock

Journal:

Cellular Microbiology

Year:

2008

Language:

english

File:

PDF, 528 KB

english, 2008

50

Phagocytosis of melanized Aspergillus conidia by macrophages exerts cytoprotective effects by sustained PI3K/Akt signalling

Katrin Volling, Andreas Thywissen, Axel A. Brakhage, Hans Peter Saluz

Journal:

Cellular Microbiology

Year:

2011

Language:

english

File:

PDF, 1.14 MB

english, 2011

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