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1

Drug-induced ototoxicity: Mechanisms, Pharmacogenetics, and protective strategies

Lanvers-Kaminsky, C, Zehnhoff-Dinnesen, AG am, Parfitt, R, Ciarimboli, G

Journal:

Clinical Pharmacology & Therapeutics

Year:

2017

Language:

english

File:

PDF, 1003 KB

english, 2017

2

Pharmacogenetics of drug-induced ototoxicity caused by aminoglycosides and cisplatin

Lanvers-Kaminsky, Claudia, Ciarimboli, Giuliano

Journal:

Pharmacogenomics

Year:

2017

Language:

english

File:

PDF, 743 KB

english, 2017

3

Borrowing Smarter or Borrowing More? Investigating the Effects of a Change in Federal Loan Policy

Lee, Jason C., Ciarimboli, Erin B., Rubin, Paul G., González Canché, Manuel S.

Journal:

The Journal of Higher Education

Year:

2019

Language:

english

File:

PDF, 948 KB

english, 2019

4

Fast simultaneous quantification of gabapentin and cetirizine in cell lysates by means of HPLC-MS/MS

Schlatt, Lukas, Costa, Ana Carolina Conchon, Barz, Vivien, Ciarimboli, Giuliano, Karst, Uwe

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2020

Language:

english

File:

PDF, 846 KB

english, 2020

5

[Reviews of Physiology, Biochemistry and Pharmacology] || Contribution and Expression of Organic Cation Transporters and Aquaporin Water Channels in Renal Cancer

Ciarimboli, Giuliano

Year:

2020

File:

PDF, 625 KB

2020

6

Regulation of the human organic cation transporter hOCT1

Giuliano Ciarimboli, Katja Struwe, Petra Arndt, Valentin Gorboulev, Hermann Koepsell, Eberhard Schlatter, Jochen R. Hirsch

Journal:

Journal of Cellular Physiology

Year:

2004

Language:

english

File:

PDF, 220 KB

english, 2004

7

Lung tissue binding of iodobenzyl-propanediamine: Involvement of beta-adrenergic receptors

A. Paci, G. Ciarimboli, M. Miniati, F. Cocci, F. Piras, M. Pistolesi

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1989

Language:

english

File:

PDF, 444 KB

english, 1989

8

Binding of 14C-furosemide to isolated human erythrocytes

A. Paci, F. Cocci, G. Ciarimboli, F. Piras, A. Tonelli, S. Ghione

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1989

Language:

english

File:

PDF, 518 KB

english, 1989

9

Calmodulin-associated post-translational regulation of rat organic cation transporter 2 in the kidney is gender dependent

S. Wilde, E. Schlatter, H. Koepsell, B. Edemir, S. Reuter, H. Pavenstädt, U. Neugebauer, R. Schröter, S. Brast, G. Ciarimboli

Journal:

Cellular and Molecular Life Sciences

Year:

2009

Language:

english

File:

PDF, 1.38 MB

english, 2009

10

LAPTM4Ainteracts withhOCT2and regulates its endocytotic recruitment

A. Grabner, S. Brast, S. Sucic, S. Bierer, B. Hirsch, H. Pavenstädt, H. H. Sitte, E. Schlatter, G. Ciarimboli

Journal:

Cellular and Molecular Life Sciences

Year:

2011

Language:

english

File:

PDF, 649 KB

english, 2011

11

The Organic Cation Transporters rOCT1 and hOCT2 Are Inhibited by cGMP

E. Schlatter, V. Mönnich, I. Çetinkaya, T. Mehrens, G. Ciarimboli, J.R. Hirsch, C. Popp, H. Koepsell

Journal:

Journal of Membrane Biology

Year:

2002

Language:

english

File:

PDF, 181 KB

english, 2002

12

Regulation of organic cation transport

Giuliano Ciarimboli, Eberhard Schlatter

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2005

Language:

english

File:

PDF, 553 KB

english, 2005

13

Properties and regulation of organic cation transport in freshly isolated mouse proximal tubules analyzed with a fluorescence reader-based method

Svenja K. Holle, Giuliano Ciarimboli, Bayram Edemir, Ute Neugebauer, Hermann Pavenstädt, Eberhard Schlatter

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2011

Language:

english

File:

PDF, 402 KB

english, 2011

14

Role of albumin and glomerular capillary wall charge distribution on glomerular permselectivity: studies on the perfused-fixed rat kidney model

G. Ciarimboli, H.-J. Schurek, M. Zeh, H. Flohr, A. Bökenkamp, L. M. Fels, I. Kilian, H. Stolte

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 108 KB

english, 1999

15

Duplication 8q22.1-q24.1 associated with bipolar disorder and speech delay

JF Macayran, SG Brodie, PN Rao, MJ O'Connor, JA Gray, B Ciarimboli, KM Dipple

Journal:

Bipolar Disorders

Year:

2006

Language:

english

File:

PDF, 271 KB

english, 2006

16

Cisplatin Nephrotoxicity Is Critically Mediated via the Human Organic Cation Transporter 2

Giuliano Ciarimboli, Thomas Ludwig, Detlef Lang, Hermann Pavenstädt, Hermann Koepsell, Hans-Jürgen Piechota, Jörg Haier, Ulrich Jaehde, Jochen Zisowsky, Eberhard Schlatter

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 300 KB

english, 2005

17

Organic Cation Transporter 2 Mediates Cisplatin-Induced Oto- and Nephrotoxicity and Is a Target for Protective Interventions

Giuliano Ciarimboli, Dirk Deuster, Arne Knief, Michael Sperling, Michael Holtkamp, Bayram Edemir, Hermann Pavenstädt, Claudia Lanvers-Kaminsky, Antoinette am Zehnhoff-Dinnesen, Alfred H. Schinkel, Her

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 1018 KB

english, 2010

18

Cimetidine as an Organic Cation Transporter Antagonist

Hans Ehrsson, Inger Wallin, Giuliano Ciarimboli, Eberhard Schlatter

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 48 KB

english, 2010

19

The cysteines of the extracellular loop are crucial for trafficking of human organic cation transporter 2 to the plasma membrane and are involved in oligomerization

Brast, S., Grabner, A., Sucic, S., Sitte, H. H., Hermann, E., Pavenstadt, H., Schlatter, E., Ciarimboli, G.

Journal:

The FASEB Journal

Year:

2012

Language:

english

File:

PDF, 587 KB

english, 2012

20

Proximal Tubular Secretion of Creatinine by Organic Cation Transporter OCT2 in Cancer Patients

Ciarimboli, G., Lancaster, C. S., Schlatter, E., Franke, R. M., Sprowl, J. A., Pavenstadt, H., Massmann, V., Guckel, D., Mathijssen, R. H. J., Yang, W., Pui, C.-H., Relling, M. V., Herrmann, E., Sparr

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 628 KB

english, 2012

21

Evaluation of the clinical efficacy of idebenone in patients affected by chronic cerebrovascular disorders

Mario Lingetti, Francesco Antonio Porfido, Mario Ciarimboli, Ugo Oliviero, Manlio Cocozza, Vincenzo Coto, Domenico Policicchio, Saverio Carifi, Efrem Piermatteo, Rosanna Lombardi, Emilio Tranfaglia, F

Journal:

Archives of Gerontology and Geriatrics

Year:

1992

Language:

english

File:

PDF, 724 KB

english, 1992

22

Steady-state pharmacokinetics of idebenone in patients with moderate renal impairment

Vincenzo Coto, Ugo Oliviero, Paolo Sorrentino, Manlio Cocozza, Mario Ciarimboli, Mario Lingetti

Journal:

Archives of Gerontology and Geriatrics

Year:

1992

Language:

english

File:

PDF, 385 KB

english, 1992

23

Role of organic cation transporters in drug-induced toxicity

Ciarimboli, Giuliano

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2011

Language:

english

File:

PDF, 395 KB

english, 2011

24

Quantitative bioimaging of platinum in polymer embedded mouse organs using laser ablation ICP-MS

Reifschneider, Olga, Wehe, Christoph A., Raj, Indra, Ehmcke, Jens, Ciarimboli, Giuliano, Sperling, Michael, Karst, Uwe

Journal:

Year:

2013

Language:

english

File:

PDF, 2.47 MB

english, 2013

25

Role of albumin and glomerular capillary wall charge distribution on glomerular permselectivity: studies on the perfused-fixed rat kidney model

G. Ciarimboli, H.-J. Schurek, M. Zeh, H. Flohr, A. Bökenkamp, L. M. Fels…

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 108 KB

english, 1999

26

Assessing the intracellular concentration of platinum in medulloblastoma cell lines after Cisplatin incubation

Wehe, Christoph A., Beyer, Georg, Sperling, Michael, Ciarimboli, Giuliano, Karst, Uwe

Journal:

Journal of Trace Elements in Medicine and Biology

Year:

2014

Language:

english

File:

PDF, 668 KB

english, 2014

27

Cisplatin-Induced Renal Injury Is Independently Mediated by OCT2 and p53

Sprowl, J. A., Lancaster, C. S., Pabla, N., Hermann, E., Kosloske, A. M., Gibson, A. A., Li, L., Zeeh, D., Schlatter, E., Janke, L. J., Ciarimboli, G., Sparreboom, A.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

28

Evaluation of Pharmacogenetic Markers to Predict the Risk of Cisplatin-Induced Ototoxicity

Lanvers-Kaminsky, C, Malath, I, Deuster, D, Ciarimboli, G, Boos, J, am Zehnhoff-Dinnesen, A G

Journal:

Clinical Pharmacology & Therapeutics

Year:

2014

Language:

english

File:

PDF, 275 KB

english, 2014

29

Substrate- and Cell Contact-Dependent Inhibitor Affinity of Human Organic Cation Transporter 2: Studies with Two Classical Organic Cation Substrates and the Novel Substrate Cd 2+

Thévenod, Frank, Ciarimboli, Giuliano, Leistner, Marcus, Wolff, Natascha A., Lee, Wing-Kee, Schatz, Irina, Keller, Thorsten, Al-Monajjed, Rouvier, Gorboulev, Valentin, Koepsell, Hermann

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 1.45 MB

english, 2013

30

Kidney Transplantation Down-Regulates Expression of Organic Cation Transporters, Which Translocate β-Blockers and Fluoroquinolones

Ciarimboli, Giuliano, Schröter, Rita, Neugebauer, Ute, Vollenbröker, Beate, Gabriëls, Gert, Brzica, Hrvoje, Sabolić, Ivan, Pietig, Gesine, Pavenstädt, Hermann, Schlatter, Eberhard, Edemir, Bayram

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 4.52 MB

english, 2013

31

New Clues for Nephrotoxicity Induced by Ifosfamide: Preferential Renal Uptake via the Human Organic Cation Transporter 2

Ciarimboli, Giuliano, Holle, Svenja Kristina, Vollenbröcker, Beate, Hagos, Yohannes, Reuter, Stefan, Burckhardt, Gerhard, Bierer, Stefan, Herrmann, Edwin, Pavenstädt, Hermann, Rossi, Rainer, Kleta,

Journal:

Molecular Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 1.10 MB

english, 2011

32

THE “FIXED” CHARGE OF GLOMERULAR CAPILLARY WALL AS DETERMINANT OF PERMSELECTIVITY

Ciarimboli, Giuliano, Bökenkamp, Arend, Schurek, Hans-Joachim, Fels, Lüder M., Kilian, Iris, Maeß, Bärbel, Stolte, Hilmar

Journal:

Year:

2001

Language:

english

File:

PDF, 1.48 MB

english, 2001

33

Organic cation transporters

Journal:

Year:

2008

Language:

english

File:

PDF, 822 KB

english, 2008

34

CYSTATIN C IN A RAT MODEL OF END-STAGE RENAL FAILURE

Bökenkamp, Arend, Ciarimboli, Giuliano, Dieterich, Christian

Journal:

Year:

2001

Language:

english

File:

PDF, 196 KB

english, 2001

35

Laser ablation based bioimaging with simultaneous elemental and molecular mass spectrometry: towards spatially resolved speciation analysis

Herdering, Christina, Wehe, Christoph A., Reifschneider, Olga, Raj, Indra, Ciarimboli, Giuliano, Diebold, Kurt, Becker, Christoph, Sperling, Michael, Karst, Uwe

Journal:

Rapid Communications in Mass Spectrometry

Year:

2013

Language:

english

File:

PDF, 721 KB

english, 2013

36

Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

Sprowl, J. A., Ciarimboli, G., Lancaster, C. S., Giovinazzo, H., Gibson, A. A., Du, G., Janke, L. J., Cavaletti, G., Shields, A. F., Sparreboom, A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 1.18 MB

english, 2013

37

Individual PKC-Phosphorylation Sites in Organic Cation Transporter 1 Determine Substrate Selectivity and Transport Regulation

Journal:

Journal of the American Society of Nephrology

Year:

2005

Language:

english

File:

PDF, 299 KB

english, 2005

38

A8.23 Carrier-mediated transport systems for specific targeting of tyrosine kinase signalling pathways in rheumatoid arthritis

Harrach, S., Edemir, B., Schlatter, E., Pap, T., Ciarimboli, G., Bertrand, J.

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 101 KB

english, 2015

39

Membrane Transporters as Mediators of Cisplatin Effects and Side Effects

Ciarimboli, Giuliano

Journal:

Year:

2012

Language:

english

File:

PDF, 262 KB

english, 2012

40

Regulation of Organic Cation Transport in Isolated Mouse Proximal Tubules Involves Complex Changes in Protein Trafficking and Substrate Affinity

Guckel, Denise, Ciarimboli, Giuliano, Pavenstädt, Hermann, Schlatter, Eberhard

Journal:

Cellular Physiology and Biochemistry

Year:

2012

Language:

english

File:

PDF, 10.58 MB

english, 2012

41

Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity

Sturm, A., Gorboulev, V., Gorbunov, D., Keller, T., Volk, C., Schmitt, B. M., Schlachtbauer, P., Ciarimboli, G., Koepsell, H.

Journal:

AJP Renal Physiology

Year:

2007

Language:

english

File:

PDF, 282 KB

english, 2007

42

Unraveling the ceramide-calpain-caspase connection in cadmium-induced apoptosis: a novel role for ceramides as activators of calpains. Focus on "Cadmium-induced ceramide formation triggers calpain-dependent apoptosis in cultured kidney proximal tubule cells"

Journal:

AJP Cell Physiology

Year:

2007

Language:

english

File:

PDF, 55 KB

english, 2007

43

Organic cation transporters OCT1, 2, and 3 mediate high-affinity transport of the mutagenic vital dye ethidium in the kidney proximal tubule

Lee, W.-K., Reichold, M., Edemir, B., Ciarimboli, G., Warth, R., Koepsell, H., Thevenod, F.

Journal:

AJP Renal Physiology

Year:

2009

Language:

english

File:

PDF, 1.16 MB

english, 2009

44

Role of transporters in the distribution of platinum-based drugs

Harrach, Saliha, Ciarimboli, Giuliano

Journal:

Frontiers in Pharmacology

Year:

2015

Language:

english

File:

PDF, 387 KB

english, 2015

45

Elemental Bioimaging by Means of Fast Scanning Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry

Wehe, Christoph A., Thyssen, Georgina M., Herdering, Christina, Raj, Indra, Ciarimboli, Giuliano, Sperling, Michael, Karst, Uwe

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2015

Language:

english

File:

PDF, 5.45 MB

english, 2015

46

Terminales Nierenversagen nach Sarkomtherapie – Fall 3/2014

Baumann, D., Amann, K., Schlatter, E., Ciarimboli, G., Kopp, H.G., Müller, M., Kluba, T., Bakos, G., Steinke, I., Bunz, H., Weyrich, P., Artunc, F.

Journal:

DMW - Deutsche Medizinische Wochenschrift

Year:

2014

Language:

german

File:

PDF, 4.09 MB

german, 2014

47

Quantitative imaging of platinum based on laser ablation-inductively coupled plasma-mass spectrometry to investigate toxic side effects of cisplatin

Köppen, C., Reifschneider, O., Castanheira, I., Sperling, M., Karst, U., Ciarimboli, G.

Journal:

Year:

2015

Language:

english

File:

PDF, 3.88 MB

english, 2015

48

Organic Cation Transporters ||

Ciarimboli, Giuliano, Gautron, Sophie, Schlatter, Eberhard

Year:

2016

Language:

english

File:

PDF, 5.68 MB

english, 2016

49

Organic Cation Transporters || Role of Transporters for Organic Cations in Plants for Environmental Cycling of Pharmaceutical Residues

Ciarimboli, Giuliano, Gautron, Sophie, Schlatter, Eberhard

Year:

2016

Language:

english

File:

PDF, 509 KB

english, 2016

50

Organic Cation Transporters || Pharmacological and Toxicological Significance of the Organic Cation Transporters OCT and MATE: Drug Disposition, Interaction and Toxicity

Ciarimboli, Giuliano, Gautron, Sophie, Schlatter, Eberhard

Year:

2016

Language:

english

File:

PDF, 524 KB

english, 2016