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101

Novel 3-Carboxamide-coumarins as Potent and Selective FXIIa Inhibitors

Robert, Séverine, Bertolla, Carine, Masereel, Bernard, Dogné, Jean-Michel, Pochet, Lionel

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

102

3-(Alkylamino)-4H-pyrido[4,3-e]1,2,4-thiadiazine 1,1-dioxides as powerful inhibitors of insulin release from rat pancreatic B-cells: a new class of potassium channel openers?

Pirotte, Bernard, de Tullio, Pascal, Lebrun, Philippe, Antoine, Marie Helene, Fontaine, Jeanine, Masereel, Bernard, Schynts, Marc, Dupont, Leon, Herchuelz, Andre, Delarge, Jacques

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 391 KB

english, 1993

103

3,6-Disubstituted Coumarins as Mechanism-Based Inhibitors of Thrombin and Factor Xa

Frédérick, Raphaël, Robert, Séverine, Charlier, Caroline, de Ruyck, Jérôme, Wouters, Johan, Pirotte, Bernard, Masereel, Bernard, Pochet, Lionel

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 327 KB

english, 2005

104

Indanesulfonamides as Carbonic Anhydrase Inhibitors. Toward Structure-Based Design of Selective Inhibitors of the Tumor-Associated Isozyme CA IX

Thiry, Anne, Ledecq, Marie, Cecchi, Alessandro, Dogné, Jean-Michel, Wouters, Johan, Supuran, Claudiu T., Masereel, Bernard

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 282 KB

english, 2006

105

Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins

Maresca, Alfonso, Temperini, Claudia, Pochet, Lionel, Masereel, Bernard, Scozzafava, Andrea, Supuran, Claudiu T.

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 4.37 MB

english, 2010

106

Esters and Amides of 6-(Chloromethyl)-2-oxo-2 H -1-benzopyran-3-carboxylic Acid as Inhibitors of α-Chymotrypsin: Significance of the “Aromatic” Nature of the Novel Ester-Type Coumarin for Strong Inhibitory Activity

Pochet, Lionel, Doucet, Caroline, Schynts, Marc, Thierry, Nicole, Boggetto, Nicole, Pirotte, Bernard, Jiang, Kai Y., Masereel, Bernard, de Tullio, Pascal, Delarge, Jacques, Reboud-Ravaux, Michèle

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 193 KB

english, 1996

107

Synthesis and Anticonvulsant Activity of 2(3 H )-Benzoxazolone and 2(3 H )-Benzothiazolone Derivatives

Ucar, Huseyin, Van derpoorten, Kim, Cacciaguerra, Silvia, Spampinato, Santi, Stables, James P., Depovere, Paul, Isa, Majed, Masereel, Bernard, Delarge, Jacques, Poupaert, Jacques H.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 112 KB

english, 1998

108

Design, Synthesis, and Anticonvulsant Activity of 1-(Pyrid-3-ylsulfonamido)-2-nitroethylenes

Masereel, Bernard, Wouters, Johan, Pochet, Lionel, Lambert, Didier

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 135 KB

english, 1998

109

Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators

Dolušić, Eduard, Larrieu, Pierre, Moineaux, Laurence, Stroobant, Vincent, Pilotte, Luc, Colau, Didier, Pochet, Lionel, Van den Eynde, Benoît, Masereel, Bernard, Wouters, Johan, Frédérick, Raphaë

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.42 MB

english, 2011

110

Anti-virulence Strategy against Brucella suis: Synthesis, Biological Evaluation and Molecular Modeling of Selective Histidinol Dehydrogenase Inhibitors

Abdo, Marie-Rose, Joseph, Pascale, Mortier, Jérémie, Turtaut, François, Montero, Jean-Louis, Masereel, Bernard, Köhler, Stephan, Winum, Jean-Yves

Journal:

Organic & Biomolecular Chemistry

Year:

2011

Language:

english

File:

PDF, 583 KB

english, 2011

111

Thiosemicarbazide, a fragment with promising indolamine-2,3-dioxygenase (IDO) inhibition properties

Serra, Silvia, Moineaux, Laurence, Vancraeynest, Christelle, Masereel, Bernard, Wouters, Johan, Pochet, Lionel, Frédérick, Raphaël

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.57 MB

english, 2014

112

Can TiC nanoparticles produce toxicity in oral administration to rats?

Laloy, Julie, Lozano, Omar, Alpan, Lütfiye, Mejia, Jorge, Toussaint, Olivier, Masereel, Bernard, Dogné, Jean-Michel, Lucas, Stéphane

Journal:

Toxicology Reports

Year:

2014

Language:

english

File:

PDF, 1.35 MB

english, 2014

113

Synthesis and Anticonvulsant Activity of 2(3 H )-Benzoxazolone and 2(3 H )-Benzothiazolone Derivatives

Ucar, Huseyin, Van derpoorten, Kim, Cacciaguerra, Silvia, Spampinato, Santi, Stables, James P., Depovere, Paul, Isa, Majed, Masereel, Bernard, Delarge, Jacques, Poupaert, Jacques H.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 12 KB

english, 1998

114

3- and 4-Substituted 4 H -Pyrido[4,3- e ]-1,2,4-thiadiazine 1,1-Dioxides as Potassium Channel Openers: Synthesis, Pharmacological Evaluation, and Structure−Activity Relationships

de Tullio, Pascal, Pirotte, Bernard, Lebrun, Philippe, Fontaine, Jeanine, Dupont, Léon, Antoine, Marie-Hélène, Ouedraogo, Raogo, Khelili, Smail, Maggetto, Carine, Masereel, Bernard, Diouf, Ousmane, Po

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 478 KB

english, 1996

115

Anticonvulsant Activity and Interactions with Neuronal Voltage-Dependent Sodium Channel of Analogues of Ameltolide

Vamecq, Joseph, Lambert, Didier, Poupaert, Jacques H., Masereel, Bernard, Stables, James P.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 88 KB

english, 1998

116

Carbonic Anhydrase Inhibitors: Bioreductive Nitro-Containing Sulfonamides with Selectivity for Targeting the Tumor Associated Isoforms IX and XII ∇

D’Ambrosio, Katia, Vitale, Rosa-Maria, Dogné, Jean-Michel, Masereel, Bernard, Innocenti, Alessio, Scozzafava, Andrea, De Simone, Giuseppina, Supuran, Claudiu T.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.15 MB

english, 2008

117

Antibody-functionalized polymer-coated gold nanoparticles targeting cancer cells: an in vitro and in vivo study

Marega, Riccardo, Karmani, Linda, Flamant, Lionel, Nageswaran, Praveen Ganesh, Valembois, Vanessa, Masereel, Bernard, Feron, Olivier, Borght, Thierry Vander, Lucas, Stephane, Michiels, Carine, Gallez,

Journal:

Journal of Materials Chemistry

Year:

2012

Language:

english

File:

PDF, 488 KB

english, 2012

118

Therapeutic potential of thromboxane inhibitors in asthma

Pirotte, Bernard, Benoit, Patricia, Dogné, Jean-Michel, Masereel, Bernard, Rolin, Stephanie, Leval, Xavier de

Journal:

Expert Opinion on Investigational Drugs

Year:

2002

Language:

english

File:

PDF, 121 KB

english, 2002

119

A comparison of six major platelet functional tests to assess the impact of carbon nanomaterials on platelet function: A practical guide

Laloy, Julie, Mullier, François, Alpan, Lutfiye, Mejia, Jorge, Lucas, Stéphane, Chatelain, Bernard, Toussaint, Olivier, Masereel, Bernard, Rolin, Stéphanie, Dogné, Jean-Michel

Journal:

Year:

2014

Language:

english

File:

PDF, 1.21 MB

english, 2014

120

4-Acylamino-4 H -1,2,4-triazoles and related structures: new investigations of their chemical and physicochemical properties associated with their particular exocyclic amide function

Pirotte, Bernard, Tullio, Pascal De, Masereel, Bernard, Schynts, Marc, Delarge, Jacques, Dupont, Léon, Thunus, Léopold

Journal:

Canadian Journal of Chemistry

Year:

1993

Language:

english

File:

PDF, 650 KB

english, 1993

121

Evaluation of the Inhibitory Activity on Serine and Aspartic Proteases of 4-Amino-4H-1,2,4-triazole and 5-Aminothiazole Derivatives Structurally Related to β-Lactam Antibiotics

A. Vilain, B. Pirotte, I. Vergely, N. Boggetto, B. Masereel, M. Schynts, J. Delarge, M. Reboud-ravaux

Year:

1993

Language:

english

File:

PDF, 581 KB

english, 1993

122

Recent developments of thromboxane modulators

Masereel, Bernard, Dogné, Jean-Michel, Delarge, Jacques, Leval, Xavier de

Journal:

Expert Opinion on Therapeutic Patents

Year:

2001

Language:

english

File:

PDF, 186 KB

english, 2001

123

Radioimmunotherapy with radioactive nanoparticles: First results of dosimetry for vascularized and necrosed solid tumors

Bouchat, V., Nuttens, V. E., Lucas, S., Michiels, C., Masereel, B., Féron, O., Gallez, B., Borght, T. Vander

Journal:

Medical Physics

Year:

2007

Language:

english

File:

PDF, 1.30 MB

english, 2007

124

Effects of reperfusion on left ventricular hemodynamics and ventriculo-arterial coupling in acutely ischemic pigs

Lanoye, L., Kolh, P., Rolin, S., Tchana-Sato, V., Dogne, J. M., Ghuysen, A., Lambermont, B., Magis, D., Hanson, J., Segers, P., Gerard, P., Masereel, B., D'Orio, V., Limet, R.

Journal:

Computer Methods in Biomechanics & Biomedical Engineering

Year:

2005

Language:

english

File:

PDF, 69 KB

english, 2005

125

Effects of BM-573, a Novel Thromboxane A2 Inhibitor, on Pulmonary Hemodynamics in Endotoxic Shock

Lambermont, B., Ghuysen, A., Dogné, J.-M., Kolh, P., Tchana-Sato, V., Morimont, P., Benoit, P., Gérard, P., Masereel, B., D’Orio, V.

Journal:

Archives of Physiology and Biochemistry

Year:

2003

Language:

english

File:

PDF, 139 KB

english, 2003

126

Effects of U-46619 on Pulmonary Hemodynamics Before and After Administration of BM-573, a Novel Thromboxane A2 Inhibitor

Lambermont, B., Kolh, P., Dogné, J.-M., Ghuysen, A., Tchana-Sato, V., Morimont, P., Benoit, P., Gérard, P., Masereel, B., Limet, R., D’Orio, V.

Journal:

Archives of Physiology and Biochemistry

Year:

2003

Language:

english

File:

PDF, 108 KB

english, 2003

127

Validation of the calibrated thrombin generation test (cTGT) as the reference assay to evaluate the procoagulant activity of nanomaterials

Laloy, Julie, Robert, Séverine, Marbehant, Catherine, Mullier, François, Mejia, Jorge, Piret, Jean-Pascal, Lucas, Stéphane, Chatelain, Bernard, Dogné, Jean-Michel, Toussaint, Olivier, Masereel, Bernar

Journal:

Year:

2012

Language:

english

File:

PDF, 963 KB

english, 2012

128

3-Bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate inhibits cancer cell invasion in vitro and tumour growth in vivo

Kempen, I, Papapostolou, D, Thierry, N, Pochet, L, Counerotte, S, Masereel, B, Foidart, J-M, Reboud-Ravaux, M, Noël, A, Pirotte, B

Journal:

British Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 203 KB

english, 2003

129

Degrémont’s largest nanofiltration plant: NOM removal at the Vegi 2000

Tinghir, Amandine, Bonnelye, Véronique, Masereel, Philippe

Journal:

DESALINATION AND WATER TREATMENT

Year:

2009

Language:

english

File:

PDF, 931 KB

english, 2009

130

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

Pilotte, L., Larrieu, P., Stroobant, V., Colau, D., Dolusic, E., Frederick, R., De Plaen, E., Uyttenhove, C., Wouters, J., Masereel, B., Van den Eynde, B. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2012

Language:

english

File:

PDF, 775 KB

english, 2012

131

3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties

Meinguet, Céline, Bruyère, Céline, Frédérick, Raphaël, Mathieu, Véronique, Vancraeynest, Christelle, Pochet, Lionel, Laloy, Julie, Mortier, Jérémie, Wolber, Gerhard, Kiss, Robert, Masereel, Bernard, W

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 9.49 MB

english, 2015

132

Differential toxicity of copper (II) oxide nanoparticles of similar hydrodynamic diameter on human differentiated intestinal Caco-2 cell monolayers is correlated in part to copper release and shape

Piret, Jean-Pascal, Vankoningsloo, Sébastien, Mejia, Jorge, Noël, Florence, Boilan, Emmanuelle, Lambinon, Françoise, Zouboulis, Christos C., Masereel, Bernard, Lucas, Stéphane, Saout, Christelle, Tous

Journal:

Year:

2012

Language:

english

File:

PDF, 906 KB

english, 2012

133

Influence of mouse strain on ovarian tissue recovery after engraftment with angiogenic factor

Fransolet, Maïté, Henry, Laurie, Labied, Soraya, Masereel, Marie-Caroline, Blacher, Silvia, Noël, Agnès, Foidart, Jean-Michel, Nisolle, Michelle, Munaut, Carine

Journal:

Journal of Ovarian Research

Year:

2015

Language:

english

File:

PDF, 1.35 MB

english, 2015

134

Dual Carbonic Anhydrase - Cyclooxygenase-2 Inhibitors

Dogne, Jean-Michel, Thiry, Anne, Pratico, Domenico, Masereel, Bernard, Supuran, Claudiu

Journal:

Current Topics in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 239 KB

english, 2007

135

Carbonic Anhydrase Inhibitors as Anticonvulsant Agents

Thiry, Anne, Dogne, Jean-Michel, Supuran, Claudiu, Masereel, Bernard

Journal:

Current Topics in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 350 KB

english, 2007

136

Effects of endotoxic shock on right ventricular systolic function and mechanical efficiency

LAMBERMONT, B, GHUYSEN, A, KOLH, P, TCHANASATO, V, SEGERS, P, GERARD, P, MORIMONT, P, MAGIS, D, DOGNE, J, MASEREEL, B

Journal:

Cardiovascular Research

Year:

2003

Language:

english

File:

PDF, 247 KB

english, 2003

137

Preparation and characterization of a new harmine-based antiproliferative compound in complex with cyclodextrin: Increasing solubility while maintaining biological activity

Meinguet, Céline, Masereel, Bernard, Wouters, Johan

Journal:

European Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

138

Correction to Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins

Maresca, Alfonso, Temperini, Claudia, Pochet, Lionel, Masereel, Bernard, Scozzafava, Andrea, Supuran, Claudiu T.

Journal:

Journal of Medicinal Chemistry

Year:

2015

File:

PDF, 104 KB

2015

139

Limited inflammatory response in rats after acute exposure to a silicon carbide nanoaerosol

Laloy, J., Lozano, O., Alpan, L., Masereel, B., Toussaint, O., Dogné, J. M., Lucas, S.

Journal:

Journal of Nanoparticle Research

Year:

2015

Language:

english

File:

PDF, 1.45 MB

english, 2015

140

New Trends in Thromboxane and Prostacyclin Modulators

Dogne, Jean, Leval, Xavier, Delarge, Jacques, David, Jean, Masereel, Bernard

Journal:

Current Medicinal Chemistry

Year:

2000

File:

PDF, 117 KB

2000

141

New Trends in Thromboxane and Prostacyclin Modulators

Dogne, Jean, Leval, Xavier, Delarge, Jacques, David, Jean, Masereel, Bernard

Journal:

Current Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 117 KB

english, 2000

142

Recent Advances in Antiplatelet Agents

Dogne, Jean-Michel, Leval, Xavier, Benoit, Patricia, Delarge, Jacques, Masereel, Bernard, David, Jean-Louis

Journal:

Current Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 80 KB

english, 2002

143

Modulators of the Coagulation Cascade: Focus and Recent Advances in Inhibitors of Tissue Factor, Factor VIIa and their Complex

Frederick, R., Pochet, L., Charlier, C., Masereel, B.

Journal:

Current Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 502 KB

english, 2005

144

New Developments on Thromboxane Modulators

Dogne, Jean-Michel, Hanson, Julien, Leval, Xavier, Masereel, Bernard, Kolh, Philippe, Pirotte, Bernard

Journal:

Mini Reviews in Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 155 KB

english, 2004

145

Eight Woodcuts

Journal:

Year:

2004

Language:

english

File:

PDF, 496 KB

english, 2004

146

New Developments on Thromboxane and Prostacyclin Modulators Part I: Thromboxane Modulators

Dogne, Jean-Michel, Leval, Xavier, Hanson, Julien, Frederich, Michel, Lambermont, Bernard, Ghuysen, Alexandre, Casini, Angela, Masereel, Bernard, Ruan, Ke-He, Pirotte, Bernard, Kolh, Philippe

Journal:

Current Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 289 KB

english, 2004

147

Rectal Duplication: a Case Report

Didden, K., Masereel, B., Geyskens, P.

Journal:

Acta Chirurgica Belgica

Year:

2013

Language:

english

File:

PDF, 813 KB

english, 2013

148

Anticonvulsant Sulfonamides/Sulfamates/Sulfamides with Carbonic Anhydrase Inhibitory Activity: Drug Design and Mechanism of Action

Masereel, Bernard, Thiry, Anne, Dogne, Jean-Michel, Supuran, Claudiu

Journal:

Current Pharmaceutical Design

Year:

2008

Language:

english

File:

PDF, 332 KB

english, 2008

149

Pneumatosis Intestinalis Caused by Ischaemic Bowel: Report of Three Cases

De Brauwer, J., Masereel, B., Visser, R., Geyskens, P.

Journal:

Acta Chirurgica Belgica

Year:

2006

Language:

english

File:

PDF, 708 KB

english, 2006

150

Supplementation of transport and freezing media with anti-apoptotic drugs improves ovarian cortex survival

Henry, Laurie, Fransolet, Maïté, Labied, Soraya, Blacher, Silvia, Masereel, Marie-Caroline, Foidart, Jean-Michel, Noel, Agnès, Nisolle, Michelle, Munaut, Carine

Journal:

Journal of Ovarian Research

Year:

2016

Language:

english

File:

PDF, 3.23 MB

english, 2016

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