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101

Combined regimen of cisplatin, doxorubicin, and α-2b interferon in the treatment of advanced malignant pleural mesothelioma : A Phase II multicenter trial of the Italian group on rare tumors (GITR) and the italian lung cancer task force (FONICAP)

Héctor Soto Parra, Lucia Tixi, Fiorenza Latteri, Sergio Bretti, Marco Alloisio, Adriano Gravina, Rita Lionetto, Paolo Bruzzi, Carla Dani, Riccardo Rosso, Maurizio Cosso, Luca Balzarini, Armando Santor

Journal:

Year:

2001

Language:

english

File:

PDF, 86 KB

english, 2001

102

Synthesis of 3-Nitrosoimidazo[1,2-a]pyridine Derivatives as Potential Antiretroviral Agents

Aziz Chaouni-Benabdallah, Christophe Galtier, Hassan Allouchi, Abdelhak Kherbeche, Jean-Claude Debouzy, Jean-Claude Teulade, Olivier Chavignon, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini,

Journal:

Archiv der Pharmazie

Year:

2001

Language:

english

File:

PDF, 91 KB

english, 2001

103

1,2,4-Triazole Derivatives Inhibiting the Human Immunodeficiency Virus Type 1 (HIV-1) in vitro

Irene M. Lagoja, Christophe Pannecouque, Laura Musumeci, Matheus Froeyen, Arthur Van Aerschot, Jan Balzarini, Piet Herdewijn, Erik De Clercq

Journal:

Helvetica Chimica Acta

Year:

2002

Language:

english

File:

PDF, 150 KB

english, 2002

104

Pridine Oxide Derivatives: Structure-Activity Relationship for Inhibition of Human Immunodeficiency Virus and Cytomegalovirus Replication in Cell Culture

Jan Balzarini, Miguel Stevens, Graciela Andrei, Robert Snoeck, Richard Strunk, James B. Pierce, John A. Lacadie, Erik De Clercq, Christophe Pannecouque

Journal:

Helvetica Chimica Acta

Year:

2002

Language:

english

File:

PDF, 135 KB

english, 2002

105

Palladium-Catalyzed Aryl Amination Reactions of 6-Bromo- and 6-Chloropurine Nucleosides

Paul F. Thomson, Pallavi Lagisetty, Jan Balzarini, Erik De Clercq, Mahesh K. Lakshman

Journal:

Advanced Synthesis & Catalysis

Year:

2010

Language:

english

File:

PDF, 225 KB

english, 2010

106

Bioreversible Maskierung von Nucleosiddiphosphaten

Henning Jacob Jessen, Tilmann Schulz, Jan Balzarini, Chris Meier

Journal:

Angewandte Chemie

Year:

2008

Language:

german

File:

PDF, 335 KB

german, 2008

107

Bioreversible Protection of Nucleoside Diphosphates

Henning Jacob Jessen, Tilmann Schulz, Jan Balzarini, Chris Meier

Journal:

Angewandte Chemie International Edition

Year:

2008

Language:

english

File:

PDF, 335 KB

english, 2008

108

Assessment of the in vitro broad-spectrum antiviral activity of some selected antitumor metallocene and metallocenium complexes

Sarah G Ward, R Craig Taylor, Petra Köpf-Maier, Hartmut Köpf, Jan Balzarini, Erik De Clercq

Journal:

Applied Organometallic Chemistry

Year:

1989

Language:

english

File:

PDF, 540 KB

english, 1989

109

Assessment of the in vitro broad-spectrum antiviral activity of some selected antitumor organotin complexes

Sarah G Ward, R Craig Taylor, Alan J Crowe, Jan Balzarini, Erik De Clercq

Journal:

Applied Organometallic Chemistry

Year:

1989

Language:

english

File:

PDF, 461 KB

english, 1989

110

Novel Carbocyclic Nucleosides Containing a Cyclopentyl Ring. Adenosine and Uridine Analogues

Carmen Balo, Franco Fernández, Evangelina Lens, Carmen López, Graciela Andrei, Robert Snoeck, Jan Balzarini, Erik De Clercq

Journal:

Archiv der Pharmazie

Year:

1997

Language:

english

File:

PDF, 339 KB

english, 1997

111

Non-nucleoside HIV Reverse Transcriptase Inhibitors, Part 6[1]: Synthesis and Anti-HIV Activity of Novel 2-[(Arylcarbonylmethyl)thio]-6-arylthio DABO Analogues

Guang-Fu Sun, Yun-Yan Kuang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque

Journal:

Archiv der Pharmazie

Year:

2005

Language:

english

File:

PDF, 91 KB

english, 2005

112

Synthesis, Antiviral and Cytostatic Evaluation of Unsaturated Exomethylene and Keto D-Lyxopyranonucleoside Analogues

Niki Tzioumaki, Evangelia Tsoukala, Stella Manta, George Agelis, Jan Balzarini, Dimitri Komiotis

Journal:

Archiv der Pharmazie

Year:

2009

Language:

english

File:

PDF, 537 KB

english, 2009

113

Synthesis of 5′-N-(α-Amino-β-mercaptoacyl)amino-5′-deoxynucleosides as potential antiviral compounds

Rosario Herranz, Julia Castro-Pichel, M. Teresa García-López, Concepción Pérez, Jan Balzarini, Erik De Clercq

Journal:

Archiv der Pharmazie

Year:

1991

Language:

english

File:

PDF, 357 KB

english, 1991

114

Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. Part 13 : Synthesis of Fluorine-Containing Diaryltriazine Derivatives for in vitro Anti-HIV Evaluation against Wild-Type Strain

Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque

Journal:

Chemistry & Biodiversity

Year:

2009

Language:

english

File:

PDF, 194 KB

english, 2009

115

Non-Nucleoside HIV-1 Reverse-Transcriptase Inhibitors. Part 10 : Synthesis and Anti-HIV Activity of 5-Alkyl-6-(1-naphthylmethyl)pyrimidin-4(3H)-ones with a Mono- or Disubstituted 2-Amino Function as Novel ‘Dihydro-Alkoxy-Benzyl-Oxopyrimidine’ (DABO) Analogues

Yueping Wang, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque

Journal:

Chemistry & Biodiversity

Year:

2008

Language:

english

File:

PDF, 227 KB

english, 2008

116

Diastereoselective Synthesis of cycloSaligenyl-Nucleosyl-Phosphotriesters

Dr. Edwuin H. Rios Morales, Prof. Dr. Jan Balzarini, Prof. Dr. Chris Meier

Journal:

Chemistry - A European Journal

Year:

2011

Language:

english

File:

PDF, 406 KB

english, 2011

117

ChemInform Abstract: Nucleosides and Nucleotides. Part 149. New Neplanocin Analogues. Part 7. Synthesis and Antiviral Activity of 2-Halo Derivatives of Neplanocin A.

T. OBARA, S. SHUTO, Y. SAITO, R. SNOECK, G. ANDREI, J. BALZARINI, E. DE CLERCQ, A. MATSUDA

Journal:

Year:

1997

File:

PDF, 36 KB

1997

118

ChemInform Abstract: Acyclic Nucleotide Analogues Derived from 8-Azapurines: Synthesis and Antiviral Activity.

A. HOLY, H. DVORAKOVA, J. JINDRICH, M. MASOJIDKOVA, M. BUDESINSKY, J. BALZARINI, G. ANDREI, E. DE CLERCQ

Journal:

Year:

1997

File:

PDF, 30 KB

1997

119

ChemInform Abstract: First Example of a 4-Amino-1,2,4,6-thiatriazine 1,1-Dioxide Derivative.

C. OCHOA, A. HERRERO, R. PROVENCIO, J. BALZARINI, E. DE CLERCQ, A. GOMEZ-BARRIO, R. MARTINEZ DIAZ, J. J. NOGAL

Journal:

Year:

1997

File:

PDF, 30 KB

1997

120

ChemInform Abstract: Phosphoramidate Derivatives of 2′,3′-Didehydro-2′,3′-dideoxyadenosine ( d4A) Have Markedly Improved Anti-HIV Potency and Selectivity.

C. MCGUIGAN, O. M. WEDGWOOD, E. DE CLERCQ, J. BALZARINI

Journal:

Year:

1997

File:

PDF, 29 KB

1997

121

ChemInform Abstract: Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6-(Aminomethyl)purines and Purine-6-carboxamidines.

M. HOCEK, M. MASOJIDKOVA, A. HOLY, G. ANDREI, R. SNOECK, J. BALZARINI, E. DE CLERCQ

Journal:

Year:

1997

File:

PDF, 34 KB

1997

122

ChemInform Abstract: Lipophilic Bioisosteres of Nucleoside Triphosphates.

A. O. GOLDRING, I. H. GILBERT, N. MAHMOOD, J. BALZARINI

Journal:

Year:

1997

File:

PDF, 26 KB

1997

123

ChemInform Abstract: Isosteres of Nucleoside Triphosphates.

R. WEAVER, I. H. GILBERT, N. MAHMOOD, J. BALZARINI

Journal:

Year:

1997

File:

PDF, 29 KB

1997

124

ChemInform Abstract: Cyclic Saligenyl Phosphotriesters of 2′,3′-Dideoxy-2′,3′- didehydrothymidine (d4T) - A New Pro-Nucleotide Approach.

C. MEIER, M. LOREY, E. DE CLERCQ, J. BALZARINI

Journal:

Year:

1997

File:

PDF, 29 KB

1997

125

ChemInform Abstract: Synthesis and Antiproliferative Activity of 2′-O-Allyl-1-β-D- arabinofuranosyl-uracil, -cytosine and -adenine.

S. MANFREDINI, P. G. BARALDI, R. BAZZANINI, D. SIMONI, J. BALZARINI, E. DE CLERCQ

Journal:

Year:

1997

File:

PDF, 33 KB

1997

126

ChemInform Abstract: Synthesis and Cytotoxic Evaluation of Some Carbohydrazones and Thiocarbohydrazones of Various Unsaturated Ketones and Related Mannich Bases.

J. R. DIMMOCK, P. KUMAR, T. M. ALLEN, G. Y. KAO, S. HALLERAN, J. BALZARINI, E. DE CLERCQ

Journal:

Year:

1997

File:

PDF, 30 KB

1997

127

ChemInform Abstract: Synthesis, Antiviral, and Cytostatic Activities of Carbocyclic Nucleosides Incorporating a Modified Cyclopentane Ring. Part 1. Guanosine Analogues.

J. M. BLANCO, O. CAAMANO, F. FERNANDEZ, G. GOMEZ, M. I. NIETO, J. BALZARINI, E. PADALKO, E. DE CLERCQ

Journal:

Year:

1997

File:

PDF, 33 KB

1997

128

ChemInform Abstract: Daunorubicin Derivatives Obtained from Daunorubicin and Nucleoside Dialdehydes

E. N. OLSUFYEVA, N. A. BRUSENTSOV, N. TODOROVA, J. BALZARINI, E. DE CLERCQ, M. N. PREOBRAZHENSKAYA

Journal:

Year:

1997

File:

PDF, 27 KB

1997

129

ChemInform Abstract: Carbocyclic Oxetanocins Lacking the C-3′ Methylene.

J. WU, S. W. SCHNELLER, K. L. SELEY, R. SNOECK, G. ANDREI, J. BALZARINI, E. DE CLERCQ

Journal:

Year:

1997

File:

PDF, 27 KB

1997

130

ChemInform Abstract: New Synthesis and Antitumor Activity of cycloSal-Derivatives of 5- Fluoro-2′-deoxyuridinemonophosphate.

M. LOREY, C. MEIER, E. DE CLERCQ, J. BALZARINI

Journal:

Year:

1997

File:

PDF, 29 KB

1997

131

ChemInform Abstract: cyclo-Saligenyl-3′-azido-2′,3′-dideoxy-thymidinemonophosphate ( cycloSal-AZTMP) - A New Pro-Nucleotide Approach?

C. MEIER, E. DE CLERCQ, J. BALZARINI

Journal:

Year:

1997

File:

PDF, 30 KB

1997

132

ChemInform Abstract: Preparation of Chloro and Sulfanyl Derivatives of 1-(2-Deoxy-4-C- hydroxymethyl-α-L-threo-pentofuranosyl)uracil.

H. HREBABECKY, J. BALZARINI, A. HOLY

Journal:

Year:

1997

File:

PDF, 33 KB

1997

133

ChemInform Abstract: Novel Carbocyclic Nucleosides Containing a Cyclopentyl Ring. Adenosine and Uridine Analogues.

C. BALO, F. FERNANDEZ, E. LENS, C. LOPEZ, G. ANDREI, R. SNOECK, J. BALZARINI, E. DE CLERCQ

Journal:

Year:

1998

File:

PDF, 30 KB

1998

134

ChemInform Abstract: Novel Analogues of the anti HIV-1 Agent TSAO-T Modified at the 3′-Spiro Moiety.

R. ALVAREZ, M.-L. JIMENO, E. DE CLERCQ, J. BALZARINI, M.-J. CAMARASA

Journal:

Year:

1998

File:

PDF, 23 KB

1998

135

ChemInform Abstract: cyclo-Saligenyl-2′,3′-dideoxy-2′,3′-didehydrothymidinemonophosphate (cycloSal-d4TMP) — A New Pronucleotide Approach.

C. MEIER, M. LOREY, E. DE CLERCQ, J. BALZARINI

Journal:

Year:

1998

File:

PDF, 30 KB

1998

136

ChemInform Abstract: Synthesis of Phosphonate Analogues of 2-Deoxyribose-1-phosphate.

M.-J. RUBIRA, M.-J. PEREZ-PEREZ, J. BALZARINI, M.-J. CAMARASA

Journal:

Year:

1998

File:

PDF, 31 KB

1998

137

ChemInform Abstract: Synthesis of (Z) and (E) α-Alkenyl Phosphonic Acid Derivatives of Purines and Pyrimidines.

H. B. LAZREK, A. ROCHDI, H. KHAIDER, J.-L. BARASCUT, J.-L. IMBACH, J. BALZARINI, M. WITVROUW, C. PANNECOUQUE, E. DE CLERCQ

Journal:

Year:

1998

File:

PDF, 35 KB

1998

138

ChemInform Abstract: Synthesis and Anti-HIV Properties of 1,2,4,6-Thiatriazin-3-one 1,1-Dioxide Nucleosides.

C. OCHOA, R. PROVENCIO, M. L. JIMENO, J. BALZARINI, E. DE CLERCQ

Journal:

Year:

1998

File:

PDF, 30 KB

1998

139

ChemInform Abstract: Design and Synthesis of Bio-Isosteres of Thymidine Triphosphate.

A. O. GOLDRING, J. BALZARINI, I. H. GILBERT

Journal:

Year:

1998

File:

PDF, 32 KB

1998

140

ChemInform Abstract: Synthesis and Biological Evaluation of 1,2-Disubstituted Carbonucleosides of 2-Amino-6-substituted Purine and 8-Azapurine.

L. SANTANA, M. TEIJEIRA, E. URIARTE, J. BALZARINI, E. DE CLERCQ

Journal:

Year:

1998

File:

PDF, 34 KB

1998

141

ChemInform Abstract: Novel Carbocyclic Nucleosides Containing a Cyclobutyl Ring. Guanosine and Adenosine Analogues.

J. E. R. BORGES, F. FERNANDEZ, X. GARCIA, A. R. HERGUETA, C. LOPEZ, G. ANDREI, R. SNOECK, M. WITVROUNW, J. BALZARINI, E. DE CLERCQ

Journal:

Year:

1998

File:

PDF, 35 KB

1998

142

ChemInform Abstract: Synthesis, Antiviral and Cytostatic Activities of Carbocyclic Nucleosides Incorporating a Modified Cyclopentane Ring. Part 2. Adenosine and Uridine Analogues.

M. I. NIETO, J. M. BLANCO, O. CAAMANO, F. FERNANDEZ, X. GARCIA-MERA, J. BALZARINI, E. PADALKO, J. NEYTS, E. DE CLERCQ

Journal:

Year:

1998

File:

PDF, 36 KB

1998

143

ChemInform Abstract: Synthesis and Chemotherapeutic Activity of a Carbocyclic Analogue of Tegafur.

C. TERAN, L. SANTANA, M. TEIJEIRA, E. URIARTE, J. BALZARINI, E. DE CLERCQ

Journal:

Year:

1998

File:

PDF, 27 KB

1998

144

ChemInform Abstract: Lactate Cannot Substitute for Alanine in D4T-Based Anti-HIV Nucleotide Prodrugs — Despite Efficient Esterase-Mediated Hydrolysis.

Christopher McGuigan, Dominique Cahard, Carlo Ballatore, Adam Siddiqui, Erik De Clercq, Jan Balzarini

Journal:

Year:

1999

File:

PDF, 28 KB

1999

145

ChemInform Abstract: 4-(β-Arylvinyl)-3-(β-arylvinylketo)-1-ethyl-4-piperidinols and Related Compounds: A Novel Class of Cytotoxic and Anticancer Agents.

J. R. DIMMOCK, S. C. VASHISHTHA, J. W. QUAIL, U. PUGAZHENTHI, Z. ZIMPEL, A. M. SUDOM, T. M. ALLEN, G. Y. KAO, J. BALZARINI, E. DE CLERCQ

Journal:

Year:

1999

File:

PDF, 34 KB

1999

146

ChemInform Abstract: Synthesis and Biological Evaluation of Phosphonate Derivatives of Some Acyclic Pyridine-C-nucleosides.

Johan Van hemel, Eddy L. Esmans, Pieter E. Joos, Alex De Groot, Roger A. Dommisse, Jan M. Balzarini, Erik D. De Clercq

Journal:

Year:

1999

File:

PDF, 29 KB

1999

147

ChemInform Abstract: Synthesis and Biological Evaluation of a Carbocyclic Azanoraristeromycin Siderophore Conjugate.

Arun Ghosh, Marvin J. Miller, Erik De Clercq, Jan Balzarini

Journal:

Year:

1999

File:

PDF, 26 KB

1999

148

ChemInform Abstract: Synthesis and Antiviral Activity of Imidazo[1,2-a]pyridines.

Mohammed Lhassani, Olivier Chavignon, Jean-Michel Chezal, Jean-Claude Teulade, Jean-Pierre Chapat, Richard Snoeck, Graciela Andrei, Jan Balzarini, Erik De Clercq, Alain Gueiffier

Journal:

Year:

1999

File:

PDF, 28 KB

1999

149

ChemInform Abstract: Structure—Antiviral Activity Relationship in the Series of Pyrimidine and Purine N-[2-(2-Phosphonomethoxy)ethyl] Nucleotide Analogues. Part 1. Derivatives Substituted at the Carbon Atoms of the Base.

Antonin Holy, Jaroslav Guenter, Hana Dvorakova, Milena Masojidkova, Graciela Andrei, Robert Snoeck, Jan Balzarini, Erik De Clercq

Journal:

Year:

1999

Language:

english

File:

PDF, 31 KB

english, 1999

150

ChemInform Abstract: Synthesis of Novel Carbocyclic Nucleosides with a Modified Cyclopentane Ring and Evaluation of Their Antiviral Activity

Isabel Nieto, M. Jose Figueira, J. Manuel Blanco, Olga Caamano, Franco Fernandez, Erik De Clercq, Jan Balzarini

Journal:

Year:

1999

File:

PDF, 26 KB

1999