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51

Response to Ji et al.: why prion diseases are precluded by non-mammals

Andrew F. Hill, Kevin J. Barnham

Journal:

Trends in Biochemical Sciences

Year:

2007

Language:

english

File:

PDF, 68 KB

english, 2007

52

The Val-210-Ile pathogenic Creutzfeldt–Jakob disease mutation increases both the helical and aggregation propensities of a sequence corresponding to helix-3 of PrPC

Andrew J. Thompson, Kevin J. Barnham, Raymond S. Norton, Colin J. Barrow

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

2001

Language:

english

File:

PDF, 391 KB

english, 2001

53

Helical structure and self-association in a 13 residue neuropeptide Y Y2 receptor agonist: relationship to biological activity

Kevin J. Barnham, Filippa Catalfamo, Paul K. Pallaghy, Geoffrey J. Howlett, Raymond S. Norton

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1999

Language:

english

File:

PDF, 621 KB

english, 1999

54

Pharmacotherapeutic targets in Alzheimer's disease

Yif'at Biran, Colin L. Masters, Kevin J. Barnham, Ashley I. Bush, Paul A. Adlard

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 5.43 MB

english, 2009

55

Structural Transitions of a GG-Platinated DNA Duplex Induced by pH, Temperature and Box A of High-Mobility-Group Protein 1

Susan J. Berners-Price, Alessandra Corazza, Zijian Guo, Kevin J. Barnham, Peter J. Sadler, Yumiko Ohyama, Marc Leng, Daniel Locker

Journal:

Year:

1997

Language:

english

File:

PDF, 943 KB

english, 1997

56

Structure of neurotoxin B-IV from the marine Worm Cerebratulus lacteus: a helical hairpin cross-linked by disulphide bonding

Kevin J. Barnham, Timothy R. Dyke, William R. Kem, Raymond S. Norton

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 1.04 MB

english, 1997

57

Chelation and Intercalation: Complementary Properties in a Compound for the Treatment of Alzheimer's Disease

Robert A. Cherny, Kevin J. Barnham, Toni Lynch, Irene Volitakis, Qiao-Xin Li, Catriona A. McLean, Gerd Multhaup, Konrad Beyreuther, Rudolph E. Tanzi, Colin L. Masters, Ashley I. Bush

Journal:

Journal of Structural Biology

Year:

2000

Language:

english

File:

PDF, 106 KB

english, 2000

58

Increased expression of the lysosomal cholesterol transporter NPC1 in Alzheimer's disease

Katarina Kågedal, Woojin Scott Kim, Hanna Appelqvist, Sharon Chan, Danni Cheng, Lotta Agholme, Kevin Barnham, Heather McCann, Glenda Halliday, Brett Garner

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 713 KB

english, 2010

59

The redox chemistry of the Alzheimer's disease amyloid β peptide

Danielle G. Smith, Roberto Cappai, Kevin J. Barnham

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2007

Language:

english

File:

PDF, 679 KB

english, 2007

60

Membrane interactions and the effect of metal ions of the amyloidogenic fragment Aβ(25–35) in comparison to Aβ(1–42)

Tong-Lay Lau, John D. Gehman, John D. Wade, Keyla Perez, Colin L. Masters, Kevin J. Barnham, Frances Separovic

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2007

Language:

english

File:

PDF, 387 KB

english, 2007

61

Dimeric structures of α-synuclein bind preferentially to lipid membranes

Eleni Giannakis, Jessica Pacífico, David P. Smith, Lin Wai Hung, Colin L. Masters, Roberto Cappai, John D. Wade, Kevin J. Barnham

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2008

Language:

english

File:

PDF, 1.07 MB

english, 2008

62

Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide

Katherine A. Price, Gulay Filiz, Aphrodite Caragounis, Tai Du, Katrina M. Laughton, Colin L. Masters, Robyn A. Sharples, Andrew F. Hill, Qiao-Xin Li, Paul S. Donnelly, Kevin J. Barnham, Peter J. Crouc

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2008

Language:

english

File:

PDF, 1.49 MB

english, 2008

63

Amyloid-β: The seeds of darkness

Michelle T. Fodero-Tavoletti, Victor L. Villemagne, Christopher C. Rowe, Colin L. Masters, Kevin J. Barnham, Roberto Cappai

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2011

Language:

english

File:

PDF, 653 KB

english, 2011

64

Interaction of the Molecular Chaperone αB-Crystallin with α-Synuclein: Effects on Amyloid Fibril Formation and Chaperone Activity

Agata Rekas, Christopher G Adda, J Andrew Aquilina, Kevin J Barnham, Margaret Sunde, Denise Galatis, Nicholas A Williamson, Colin L Masters, Robin F Anders, Carol V Robinson, Roberto Cappai, John A Ca

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 944 KB

english, 2004

65

Amyloid-β Peptide Disruption of Lipid Membranes and the Effect of Metal Ions

Tong-Lay Lau, Ernesto E. Ambroggio, Deborah J. Tew, Roberto Cappai, Colin L. Masters, Gerardo D. Fidelio, Kevin J. Barnham, Frances Separovic

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 362 KB

english, 2006

66

Structural Studies of the Alzheimer’s Amyloid Precursor Protein Copper-binding Domain Reveal How it Binds Copper Ions

Geoffrey K.-W. Kong, Julian J. Adams, Hugh H. Harris, John F. Boas, Cyril C. Curtain, Denise Galatis, Colin L. Masters, Kevin J. Barnham, William J. McKinstry, Roberto Cappai, Michael W. Parker

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.31 MB

english, 2007

67

Dopamine and the Dopamine Oxidation Product 5,6-Dihydroxylindole Promote Distinct On-Pathway and Off-Pathway Aggregation of α-Synuclein in a pH-Dependent Manner

Chi L.L. Pham, Su Ling Leong, Feda E. Ali, Vijaya B. Kenche, Andrew F. Hill, Sally L. Gras, Kevin J. Barnham, Roberto Cappai

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 1.66 MB

english, 2009

68

The structure and function of the amyloid precursor protein N-terminal region

Roberto Cappai, Anthony R. White, Gerd Multhaup, Kevin Barnham, William J. McKinstry, Elise Needham, Denise Galatis, Jamie Rossjohn

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 205 KB

english, 2000

69

Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

Robert A Cherny, Craig S Atwood, Michel E Xilinas, Danielle N Gray, Walton D Jones, Catriona A McLean, Kevin J Barnham, Irene Volitakis, Fiona W Fraser, Young-Seon Kim, Xudong Huang, Lee E Goldstein,

Journal:

Year:

2001

Language:

english

File:

PDF, 221 KB

english, 2001

70

[Methods in Molecular Biology] Protein Folding, Misfolding, and Disease Volume 752 || Refolding Your Protein with a Little Help from REFOLD

Hill, Andrew F., Barnham, Kevin J., Bottomley, Stephen P., Cappai, Roberto

Year:

2011

Language:

english

File:

PDF, 179 KB

english, 2011

71

Dimerisation of N -acetyl- l -tyrosine ethyl ester and Aβ peptides via formation of dityrosine

Ali, Feda E., Leung, Andrew, Cherny, Robert A., Mavros, Christine, Barnham, Kevin J., Separovic, Frances, Barrow, Colin J.

Journal:

Free Radical Research

Year:

2006

Language:

english

File:

PDF, 423 KB

english, 2006

72

O3-01-08: APP processing in exosomes

Andrew F. Hill, Robyn Sharples, Laura J. Vella, Rebecca M. Nisbet, Ryan Naylor, Keyla Perez, Kevin Barnham, Colin Masters

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

73

P1-125: Non–β-amyloid, nonoligomeric derivatives of APP are synaptotoxic

Ryan Naylor, Colin L. Masters, Andrew F. Hill, Kevin J. Barnham

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

74

Blood Borne Aβ Dimer Correlates With Clinical Markers of Alzheimer's Disease

Kevin J. Barnham, Keyla Perez, Kerryn Pike, Christopher Rowe, Colin Masters, Anthony White, Justin Bedo, Noel Faux, Victor Villemagne

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 51 KB

english, 2009

75

Pbt2 for Pre-dementia Alzheimer's Disease: Animal and Clinical Evidence

Ashley I. Bush, Robert A. Cherny, David Finkelstein, Colin L. Masters, Rudolph E. Tanzi, Kevin J. Barnham, Craig Ritchie, Paul A. Adlard

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

76

TDP-43 aggregation during chronic oxidative stress is mediated by c-Jun N-terminal kinase and can be inhibited by a potentially therapeutic metallo-complex

Anthony White, Colin Masters, Kevin Barnham, Peter Crouch, Qiao-Xin Li, Jodi Meyerowitz, Sarah Parker, Paul Donnelly

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 50 KB

english, 2011

77

Investigating Alzheimer's disease in the blood cellular fraction

Andrew Watt, Keyla Perez, Christopher Rowe, Victor Villemagne, Colin Masters, Kevin Barnham, Noel Faux, Kerryn Pike

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 79 KB

english, 2011

78

Profiling beta-amyloid in the Alzheimer's disease brain

Andrew Watt, Keyla Perez, Nicki Sherratt, Alan Rembach, Lin Hung, Catriona McLean, Michelle Fodero-Tavoletti, Colin Masters, Victor Villemagne, Kevin Barnham

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

79

Variability in blood-based beta-amyloid assays: The need for consensus on preanalytical processing

Andrew Watt, Keyla Perez, Alan Rembach, Colin Masters, Victor Villemagne, Kevin Barnham

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

80

Copper catalysed oxidation of amino acids and Alzheimer's disease

Feda E. Ali, Kevin J. Barnham, Colin J. Barrow, Frances Separovic

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2003

Language:

english

File:

PDF, 121 KB

english, 2003

81

Methionine oxidation: Implications for the mechanism of toxicity of the β-amyloid peptide from Alzheimer's disease

Giuseppe D. Ciccotosto, Kevin J. Barnham, Robert A. Cherny, Colin L. Masters, Ashley I. Bush, Cyril C. Curtain, Roberto Cappai, Deborah Tew

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2003

Language:

english

File:

PDF, 126 KB

english, 2003

82

Surface Behavior and Lipid Interaction of Alzheimer β-Amyloid Peptide 1–42: A Membrane-Disrupting Peptide

Ambroggio, Ernesto E., Kim, Dennis H., Separovic, Frances, Barrow, Colin J., Barnham, Kevin J., Bagatolli, Luis A., Fidelio, Gerardo D.

Journal:

Biophysical Journal

Year:

2005

Language:

english

File:

PDF, 225 KB

english, 2005

83

Stabilization of Neurotoxic Soluble β-Sheet-Rich Conformations of the Alzheimer's Disease Amyloid-β Peptide

Tew, Deborah J., Bottomley, Stephen P., Smith, David P., Ciccotosto, Giuseppe D., Babon, Jeffrey, Hinds, Mark G., Masters, Colin L., Cappai, Roberto, Barnham, Kevin J.

Journal:

Biophysical Journal

Year:

2008

Language:

english

File:

PDF, 430 KB

english, 2008

84

The Structure of the Amyloid-β Peptide High-Affinity Copper II Binding Site in Alzheimer Disease

Streltsov, Victor A., Titmuss, Stephen J., Epa, V. Chandana, Barnham, Kevin J., Masters, Colin L., Varghese, Joseph N.

Journal:

Biophysical Journal

Year:

2008

Language:

english

File:

PDF, 475 KB

english, 2008

85

Aspects of the solution chemistry of trans-diammineplatinum(II) complexes

Appleton, Trevor G., Bailey, Alicia J., Barnham, Kevin J., Hall, John R.

Journal:

Inorganic Chemistry

Year:

1992

Language:

english

File:

PDF, 793 KB

english, 1992

86

[Methods in Molecular Biology] Protein Folding, Misfolding, and Disease Volume 752 || Transmission Electron Microscopy of Amyloid Fibrils

Hill, Andrew F., Barnham, Kevin J., Bottomley, Stephen P., Cappai, Roberto

Year:

2011

Language:

english

File:

PDF, 602 KB

english, 2011

87

[Methods in Molecular Biology] Protein Folding, Misfolding, and Disease Volume 752 || Surface Plasmon Resonance Spectroscopy: A New Lead in Studying the Membrane Binding of Amyloidogenic Transthyretin

Hill, Andrew F., Barnham, Kevin J., Bottomley, Stephen P., Cappai, Roberto

Year:

2011

Language:

english

File:

PDF, 324 KB

english, 2011

88

Mixed Ligand Cu 2+ Complexes of a Model Therapeutic with Alzheimer’s Amyloid-β Peptide and Monoamine Neurotransmitters

Kenche, Vijaya B., Zawisza, Izabela, Masters, Colin L., Bal, Wojciech, Barnham, Kevin J., Drew, Simon C.

Journal:

Inorganic Chemistry

Year:

2013

Language:

english

File:

PDF, 3.49 MB

english, 2013

89

[Methods in Molecular Biology] Protein Folding, Misfolding, and Disease Volume 752 || Circular Dichroism and Its Use in Protein-Folding Studies

Hill, Andrew F., Barnham, Kevin J., Bottomley, Stephen P., Cappai, Roberto

Year:

2011

Language:

english

File:

PDF, 160 KB

english, 2011

90

Therapeutic Redistribution of Metal Ions To Treat Alzheimer’s Disease

Crouch, Peter J., Barnham, Kevin J.

Journal:

Accounts of Chemical Research

Year:

2012

Language:

english

File:

PDF, 768 KB

english, 2012

91

[Methods in Molecular Biology] Protein Folding, Misfolding, and Disease Volume 752 || Diagnostics for Amyloid Fibril Formation: Where to Begin?

Hill, Andrew F., Barnham, Kevin J., Bottomley, Stephen P., Cappai, Roberto

Year:

2011

Language:

english

File:

PDF, 188 KB

english, 2011

92

The Heterogeneous Nature of Cu 2+ Interactions with Alzheimer’s Amyloid-β Peptide

Drew, Simon C., Barnham, Kevin J.

Journal:

Accounts of Chemical Research

Year:

2011

Language:

english

File:

PDF, 2.19 MB

english, 2011

93

Copper and Zinc Binding Modulates the Aggregation and Neurotoxic Properties of the Prion Peptide PrP106−126 †

Jobling, Michael F., Huang, Xudong, Stewart, Leanne R., Barnham, Kevin J., Curtain, Cyril, Volitakis, Irene, Perugini, Matthew, White, Anthony R., Cherny, Robert A., Masters, Colin L., Barrow, Colin J

Journal:

Year:

2001

Language:

english

File:

PDF, 283 KB

english, 2001

94

Guanidine hydrochloride denaturation of dopamine-induced α-synuclein oligomers: A small-angle X-ray scattering study

Pham, Chi L. L., Kirby, Nigel, Wood, Kathleen, Ryan, Timothy, Roberts, Blaine, Sokolova, Anna, Barnham, Kevin J., Masters, Colin L., Knott, Robert B., Cappai, Roberto, Curtain, Cyril C., Rekas, Agata

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2014

Language:

english

File:

PDF, 2.25 MB

english, 2014

95

[Methods in Molecular Biology] Protein Folding, Misfolding, and Disease Volume 752 ||

Hill, Andrew F., Barnham, Kevin J., Bottomley, Stephen P., Cappai, Roberto

Year:

2011

Language:

english

File:

PDF, 5.90 MB

english, 2011

96

Progress towards a consensus on biomarkers for Alzheimer’s disease: a review of peripheral analytes

Rembach, Alan, Ryan, Tim M, Roberts, Blaine R, Doecke, James D, Wilson, William J, Watt, Andrew D, Barnham, Kevin J, Masters, Colin L

Journal:

Biomarkers in Medicine

Year:

2013

Language:

english

File:

PDF, 1.89 MB

english, 2013

97

Cu2+Coordination of Covalently Cross-linked β-Amyloid Dimers

Simon C. Drew, W. Mei Kok, Craig A. Hutton, Kevin J. Barnham

Journal:

Applied Magnetic Resonance

Year:

2013

Language:

english

File:

PDF, 1.02 MB

english, 2013

98

Therapeutic effects of Cu II (atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis

McAllum, Erin J., Lim, Nastasia K.-H., Hickey, James L., Paterson, Brett M., Donnelly, Paul S., Li, Qiao-Xin, Liddell, Jeffrey R., Barnham, Kevin J., White, Anthony R., Crouch, Peter J.

Journal:

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Year:

2013

Language:

english

File:

PDF, 319 KB

english, 2013

99

Concentration Dependent Cu 2+ Induced Aggregation and Dityrosine Formation of the Alzheimer's Disease Amyloid-β Peptide †

Smith, David P., Ciccotosto, Giuseppe D., Tew, Deborah J., Fodero-Tavoletti, Michelle T., Johanssen, Timothy, Masters, Colin L., Barnham, Kevin J., Cappai, Roberto

Journal:

Year:

2007

Language:

english

File:

PDF, 562 KB

english, 2007

100

Synthetic dityrosine-linked β-amyloid dimers form stable, soluble, neurotoxic oligomers

Kok, W. Mei, Cottam, Jade M., Ciccotosto, Giuseppe D., Miles, Luke A., Karas, John A., Scanlon, Denis B., Roberts, Blaine R., Parker, Michael W., Cappai, Roberto, Barnham, Kevin J., Hutton, Craig A.

Journal:

Chemical Science

Year:

2013

Language:

english

File:

PDF, 876 KB

english, 2013