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51

Central nervous system myeloid cells as drug targets: current status and translational challenges

Biber, Knut, Möller, Thomas, Boddeke, Erik, Prinz, Marco

Journal:

Nature Reviews Drug Discovery

Year:

2015

Language:

english

File:

PDF, 436 KB

english, 2015

52

Signaling pathways regulating Homer1a expression: implications for antidepressant therapy

Serchov, Tsvetan, Heumann, Rolf, van Calker, Dietrich, Biber, Knut

Journal:

Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 969 KB

english, 2016

53

CX 3 CL1 and CX 3 CR1 Expression in Human Brain Tissue: Noninflammatory Control versus Multiple Sclerosis

Hulshof, Sandra, van Haastert, Elise S., Kuipers, Hedwich F., van den Elsen, Peter J., de Groot, Corline J., van der Valk, Paul, Ravid, Rivka, Biber, Knut

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2003

Language:

english

File:

PDF, 276 KB

english, 2003

54

Age-related myelin degradation burdens the clearance function of microglia during aging

Safaiyan, Shima, Kannaiyan, Nirmal, Snaidero, Nicolas, Brioschi, Simone, Biber, Knut, Yona, Simon, Edinger, Aimee L, Jung, Steffen, Rossner, Moritz J, Simons, Mikael

Journal:

Nature Neuroscience

Year:

2016

Language:

english

File:

PDF, 1.59 MB

english, 2016

55

The microglial ATP-gated ion channel P2X7 as a CNS drug target

Bhattacharya, Anindya, Biber, Knut

Journal:

Year:

2016

Language:

english

File:

PDF, 752 KB

english, 2016

56

Microglia replenished OHSC: A culture system to study in vivo like adult microglia

Masuch, Annette, van der Pijl, Rianne, Füner, Lisa, Wolf, Yochai, Eggen, Bart, Boddeke, Erik, Biber, Knut

Journal:

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

57

Chemokines and Their Receptors in Central Nervous System Disease

Biber, Knut, de Jong, Eiko, van Weering, Hilmar, Boddeke, Hendrikus

Journal:

Current Drug Targets

Year:

2006

Language:

english

File:

PDF, 106 KB

english, 2006

58

Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor

Möller, Thomas, Bard, Frédérique, Bhattacharya, Anindya, Biber, Knut, Campbell, Brian, Dale, Elena, Eder, Claudia, Gan, Li, Garden, Gwenn A., Hughes, Zoë A., Pearse, Damien D., Staal, Roland G. W., Sa

Journal:

Year:

2016

Language:

english

File:

PDF, 222 KB

english, 2016

59

Forebrain microglia from wild-type but not adult 5xFAD mice prevent amyloid-β plaque formation in organotypic hippocampal slice cultures

Hellwig, Sabine, Masuch, Annette, Nestel, Sigrun, Katzmarski, Natalie, Meyer-Luehmann, Melanie, Biber, Knut

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.61 MB

english, 2015

60

Pathophysiological and behavioral effects of systemic inflammation in aged and diseased rodents with relevance to delirium: A systematic review

Schreuder, Leroy, Eggen, B.J., Biber, Knut, Schoemaker, Regien G., Laman, Jon D., de Rooij, Sophia E.

Journal:

Brain, Behavior, and Immunity

Year:

2017

Language:

english

File:

PDF, 1.43 MB

english, 2017

61

GRIN3B missense mutation as an inherited risk factor for schizophrenia: whole-exome sequencing in a family with a familiar history of psychotic disorders

HORNIG, TOBIAS, GRÜNING, BJÖRN, KUNDU, KOUSIK, HOUWAART, TORSTEN, BACKOFEN, ROLF, BIBER, KNUT, NORMANN, CLAUS

Journal:

Genetics Research

Year:

2017

Language:

english

File:

PDF, 278 KB

english, 2017

62

Reestablishing microglia function: good news for Alzheimer's therapy?

Journal:

The EMBO Journal

Year:

2017

Language:

english

File:

PDF, 286 KB

english, 2017

63

Microglial CX3CR1 promotes adult neurogenesis by inhibiting Sirt 1/p65 signaling independent of CX3CL1

Sellner, Sabine, Paricio-Montesinos, Ricardo, Spieß, Alena, Masuch, Annette, Erny, Daniel, Harsan, Laura A., Elverfeldt, Dominik v., Schwabenland, Marius, Biber, Knut, Staszewski, Ori, Lira, Sergio, J

Journal:

Acta Neuropathologica Communications

Year:

2016

Language:

english

File:

PDF, 2.96 MB

english, 2016

64

Interleukin-6 Upregulates Neuronal Adenosine A1 Receptors: Implications for Neuromodulation and Neuroprotection

Biber, Knut, Pinto-Duarte, A, Wittendorp, M C, Dolga, A M, Fernandes, C C, Von Frijtag Drabbe Künzel, J, Keijser, J N, de Vries, R, Ijzerman, A P, Ribeiro, J A, Eisel, U, Sebastião, A M, Boddeke, H W

Journal:

Neuropsychopharmacology

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

65

Activation of EP 2 receptor suppresses poly(I: C) and LPS-mediated inflammation in primary microglia and organotypic hippocampal slice cultures: Contributing role for MAPKs

Yousif, Nizar M., de Oliveira, Antonio Carlos Pinheiro, Brioschi, Simone, Huell, Michael, Biber, Knut, Fiebich, Bernd L.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.05 MB

english, 2017

66

Recent insights into antidepressant therapy: Distinct pathways and potential common mechanisms in the treatment of depressive syndromes

van Calker, Dietrich, Serchov, Tsvetan, Normann, Claus, Biber, Knut

Journal:

Neuroscience & Biobehavioral Reviews

Year:

2018

Language:

english

File:

PDF, 429 KB

english, 2018

67

KATP Channel Opener Diazoxide Prevents Neurodegeneration: A New Mechanism of Action via Antioxidative Pathway Activation

Virgili, Noemí, Mancera, Pilar, Wappenhans, Blanca, Sorrosal, Georgina, Biber, Knut, Pugliese, Marco, Espinosa-Parrilla, Juan F., Reddy, Hemachandra

Journal:

Year:

2013

Language:

english

File:

PDF, 9.59 MB

english, 2013

68

Adenosine Receptors Differentially Regulate the Expression of Regulators of G-Protein Signalling (RGS) 2, 3 and 4 in Astrocyte-Like Cells

Eusemann, Till Nicolas, Willmroth, Frank, Fiebich, Bernd, Biber, Knut, van Calker, Dietrich, Hu, Wenhui

Journal:

Year:

2015

Language:

english

File:

PDF, 694 KB

english, 2015

69

Cellular and Molecular Characterization of Microglia: A Unique Immune Cell Population

Sousa, Carole, Biber, Knut, Michelucci, Alessandro

Journal:

Frontiers in Immunology

Year:

2017

Language:

english

File:

PDF, 1.74 MB

english, 2017

70

Neuronal CC chemokines: the distinct roles of CCL21 and CCL2 in neuropathic pain

Biber, Knut, Boddeke, Erik

Journal:

Frontiers in Cellular Neuroscience

Year:

2014

Language:

english

File:

PDF, 576 KB

english, 2014

71

Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures

Sousa, Carole, Golebiewska, Anna, Poovathingal, Suresh K, Kaoma, Tony, Pires‐Afonso, Yolanda, Martina, Silvia, Coowar, Djalil, Azuaje, Francisco, Skupin, Alexander, Balling, Rudi, Biber, Knut, Niclou,

Journal:

Year:

2018

Language:

english

File:

PDF, 1.54 MB

english, 2018

72

Universes in Delicate Balance || Microglial Chemokines and Chemokine Receptors

Year:

2002

Language:

english

File:

PDF, 124 KB

english, 2002

73

Adenosine A 1 Receptor-Mediated Activation of Phospholipase C in Cultured Astrocytes Depends on the Level of Receptor Expression

Biber, Knut, Klotz, Karl-Norbert, Berger, Mathias, Gebicke-Härter, Peter J., van Calker, Dietrich

Journal:

Journal of Neuroscience

Year:

1997

Language:

english

File:

PDF, 710 KB

english, 1997

74

The Role of Adenosine Receptors in Mood and Anxiety Disorders

van Calker, Dietrich, Biber, Knut, Domschke, Katharina, Serchov, Tsvetan

Journal:

Journal of Neurochemistry

Year:

2019

Language:

english

File:

PDF, 762 KB

english, 2019

75

Enhanced mGlu5 Signaling in Excitatory Neurons Promotes Rapid Antidepressant Effects via AMPA Receptor Activation

Holz, Amrei, Mülsch, Felix, Schwarz, Martin K., Hollmann, Michael, Döbrössy, Mate D., Coenen, Volker A., Bartos, Marlene, Normann, Claus, Biber, Knut, van Calker, Dietrich, Serchov, Tsvetan

Journal:

Year:

2019

Language:

english

File:

PDF, 3.02 MB

english, 2019

76

Microglial Drug Targets in AD: Opportunities and Challenges in Drug Discovery and Development

Biber, Knut, Bhattacharya, Anindya, Campbell, Brian M., Piro, Justin R., Rohe, Michael, Staal, Roland G.W., Talanian, Robert V., Möller, Thomas

Journal:

Frontiers in Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.51 MB

english, 2019

77

Microglial Drug Targets in AD: Opportunities and Challenges in Drug Discovery and Development

Biber, Knut, Bhattacharya, Anindya, Campbell, Brian M., Piro, Justin R., Rohe, Michael, Staal, Roland G.W., Talanian, Robert V., Möller, Thomas

Journal:

Frontiers in Pharmacology

Year:

2019

File:

PDF, 1.51 MB

2019

78

The neuroprotective role of microglial cells against amyloid beta‐mediated toxicity in organotypic hippocampal slice cultures

Richter, Maren, Vidovic, Natascha, Biber, Knut, Dolga, Amalia, Culmsee, Carsten, Dodel, Richard

Journal:

Brain Pathology

Year:

2019

File:

PDF, 22.75 MB

2019

79

Detection of Synaptic Proteins in Microglia by Flow Cytometry

Brioschi, Simone, dâErrico, Paolo, Amann, Lukas S., Janova, Hana, Wojcik, Sonja M., Meyer-Luehmann, Melanie, Rajendran, Lawrence, Wieghofer, Peter, Paolicelli, Rosa C., Biber, Knut

Journal:

Frontiers in Molecular Neuroscience

Year:

2020

File:

PDF, 6.41 MB

2020

80

Antidepressant treatment is associated with epigenetic alterations of Homer1 promoter in a mouse model of chronic depression

Sun, Lu, Verkaik-Schakel, Rikst-Nynke, Biber, Knut, PlÃ¶sch, Torsten, Serchov, Tsvetan

Journal:

Journal of Affective Disorders

Year:

2020

File:

PDF, 810 KB

2020

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