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51

A Novel Single-Chain Antibody Fragment for Detection of Mannose 6-Phosphate-Containing Proteins: Application in Mucolipidosis Type II Patients and Mice

Sven Müller-Loennies, Giovanna Galliciotti, Katrin Kollmann, Markus Glatzel, Thomas Braulke

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 549 KB

english, 2010

52

Effect of insulin-like growth factor II on uptake of arylsulfatase A by cultured rat hepatocytes and Kupffer cells

Frank Schmitz, Roberto Bresciani, Heinz Hartmann, Thomas Braulke

Journal:

Journal of Hepatology

Year:

1995

Language:

english

File:

PDF, 879 KB

english, 1995

53

Proteolysis of IGFBPs by cathepsin D in vitro and in cathepsin D-deficient mice

Braulke, Thomas, Claussen, Max, Saftig, Paul, Wendland, Martin, Neifer, Klaus, Schmidt, Bernhard, Zapf, Jürgen, bon Figura, Kurt, Peters, Christoph

Journal:

Progress in Growth Factor Research

Year:

1995

Language:

english

File:

PDF, 462 KB

english, 1995

54

Cellular localization and hormonal regulation of biosynthesis of insulin-like growth factor binding proteins and of the acid-labile subunit within rat liver

Scharf, Jens-Gerd, Ramadori, Giuliano, Braulke, Thomas, Hartmann, Heinz

Journal:

Progress in Growth Factor Research

Year:

1995

Language:

english

File:

PDF, 500 KB

english, 1995

55

Glycosylation- and phosphorylation-dependent intracellular transport of lysosomal hydrolases

Pohl, Sandra, Marschner, Katrin, Storch, Stephan, Braulke, Thomas

Journal:

Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 134 KB

english, 2009

56

Two different del(5q) clones in a patient with myelodysplastic syndrome

Braulke, Friederike, Schanz, Julie, Steffens, Rainer, Liehr, Thomas, Manvelyan, Marina, Chudoba, Ilse, Haase, Detlef

Journal:

Leukemia and Lymphoma

Year:

2011

Language:

english

File:

PDF, 492 KB

english, 2011

57

Acute renal proximal tubule alterations during induced metabolic crises in a mouse model of glutaric aciduria type 1

Thies, Bastian, Meyer-Schwesinger, Catherine, Lamp, Jessica, Schweizer, Michaela, Koeller, David M., Ullrich, Kurt, Braulke, Thomas, Mühlhausen, Chris

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2013

Language:

english

File:

PDF, 2.51 MB

english, 2013

58

Cell biology and function of neuronal ceroid lipofuscinosis-related proteins

Kollmann, Katrin, Uusi-Rauva, Kristiina, Scifo, Enzo, Tyynelä, Jaana, Jalanko, Anu, Braulke, Thomas

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2013

Language:

english

File:

PDF, 443 KB

english, 2013

59

P-048 Karyotype evolution detected in CD34+ peripheral blood cells of MDS patients: First results of the ongoing prospective German diagnostic study

Braulke, F., Götze, K., Müller-Thomas, C., Platzbecker, U., Giagounidis, A.A.N., Germing, U., Bug, G., Nolte, F., Brümmendorf, T.H., Haase, D.

Journal:

Leukemia Research

Year:

2013

Language:

english

File:

PDF, 89 KB

english, 2013

60

Mannose 6-phosphate/insulin-like growth factor II receptor and I-cell disease fibroblasts: increased synthesis and defective regulation of cell surface expression

Braulke, Thomas, Tippmer, Stephanie, Matzner, Ulrich, Gartung, Carsten, von Figura, Kurt

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

1992

Language:

english

File:

PDF, 953 KB

english, 1992

61

Is Movement of Mannose 6-Phosphate-Specific Receptor Triggered by Binding of Lysosomal Enzymes?

Thomas Braulke, Carsten Gartung, Andrej Hasilik and Kurt von Figura

Journal:

The Journal of Cell Biology

Year:

1987

Language:

english

File:

PDF, 1.91 MB

english, 1987

62

Molecular cytogenetic monitoring from CD34+ peripheral blood cells in myelodysplastic syndromes: First results from a prospective multicenter German diagnostic study

Braulke, Friederike, Jung, Klaus, Schanz, Julie, Götze, Katharina, Müller-Thomas, Catharina, Platzbecker, Uwe, Germing, Ulrich, Brümmendorf, Tim H., Bug, Gesine, Ottmann, Oliver, Giagounidis, Aristote

Journal:

Leukemia Research

Year:

2013

Language:

english

File:

PDF, 1.53 MB

english, 2013

63

Mass Spectrometric Analysis of Neutral and Anionic N-Glycans from a Dictyostelium discoideum Model for Human Congenital Disorder of Glycosylation CDG IL

Hykollari, Alba, Balog, Crina I. A., Rendić, Dubravko, Braulke, Thomas, Wilson, Iain B. H., Paschinger, Katharina

Journal:

Journal of Proteome Research

Year:

2013

Language:

english

File:

PDF, 2.58 MB

english, 2013

64

Partial IGF Affinity of Circulating N- and C-Terminal Fragments of Human Insulin-like Growth Factor Binding Protein-4 (IGFBP-4) and the Disulfide Bonding Pattern of the C-Terminal IGFBP-4 Domain †

Ständker, Ludger, Braulke, Thomas, Mark, Silke, Mostafavi, Hossein, Meyer, Markus, Höning, Stefan, Giménez-Gallego, Guillermo, Forssmann, Wolf-Georg

Journal:

Year:

2000

Language:

english

File:

PDF, 230 KB

english, 2000

65

Molecular Characterization of Arylsulfatase G

Kowalewski, Björn, Lübke, Torben, Kollmann, Katrin, Braulke, Thomas, Reinheckel, Thomas, Dierks, Thomas, Damme, Markus

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.95 MB

english, 2014

66

Diversity of Human Insulin-like Growth Factor (IGF) Binding Protein-2 Fragments in Plasma: Primary Structure, IGF-Binding Properties, and Disulfide Bonding Pattern †

Mark, Silke, Kübler, Bernd, Höning, Stefan, Oesterreicher, Sandra, John, Harald, Braulke, Thomas, Forssmann, Wolf-Georg, Ständker, Ludger

Journal:

Year:

2005

Language:

english

File:

PDF, 413 KB

english, 2005

67

Topology and endoplasmic reticulum retention signals of the lysosomal storage disease-related membrane protein CLN6

Heine, Claudia, Heine, Claudia, Quitsch, Arne, Storch, Stephan, Martin, Yella, Lonka, Liina, Lehesjoki, Anna-Elina, Mole, Sara E., Braulke, Thomas

Journal:

Molecular Membrame Biology

Year:

2007

Language:

english

File:

PDF, 673 KB

english, 2007

68

Mucolipidosis II-Related Mutations Inhibit the Exit from the Endoplasmic Reticulum and Proteolytic Cleavage of GlcNAc-1-Phosphotransferase Precursor Protein ( GNPTAB )

De Pace, Raffaella, Coutinho, Maria Francisca, Koch-Nolte, Friedrich, Haag, Friedrich, Prata, Maria João, Alves, Sandra, Braulke, Thomas, Pohl, Sandra

Journal:

Year:

2014

Language:

english

File:

PDF, 938 KB

english, 2014

69

BOOKS RECEIVED

Madhavarao, Chikkathur N., Agarabi, Cyrus D., Wong, Lily, Müller-Loennies, Sven, Braulke, Thomas, Khan, Mansoor, Anderson, Howard, Johnson, Gibbes R.

Journal:

British Journal of Industrial Relations

Year:

1991

Language:

english

File:

PDF, 117 KB

english, 1991

70

Evaluation of butyrate-induced production of a mannose-6-phosphorylated therapeutic enzyme using parallel bioreactors

Madhavarao, Chikkathur N., Agarabi, Cyrus D., Wong, Lily, Müller-Loennies, Sven, Braulke, Thomas, Khan, Mansoor, Anderson, Howard, Johnson, Gibbes R.

Journal:

Biotechnology and Applied Biochemistry

Year:

2014

Language:

english

File:

PDF, 981 KB

english, 2014

71

Ultrastructural Analysis of Neuronal and Non-neuronal Lysosomal Storage in Mucolipidosis Type II Knock-in Mice

Schweizer, Michaela, Markmann, Sandra, Braulke, Thomas, Kollmann, Katrin

Journal:

Ultrastructural Pathology

Year:

2013

Language:

english

File:

PDF, 2.55 MB

english, 2013

72

Endothelial Effects of 3-Hydroxyglutaric Acid: Implications for Glutaric Aciduria Type I

Mühlhausen, Chris, Ott, Nicola, Chalajour, Fariba, Tilki, Derya, Freudenberg, Folke, Shahhossini, Mona, Thiem, Joachim, Ullrich, Kurt, Braulke, Thomas, Ergün, Süleyman

Journal:

Pediatric Research

Year:

2006

Language:

english

File:

PDF, 1.46 MB

english, 2006

73

Post-translational Modifications of the γ-Subunit Affect Intracellular Trafficking and Complex Assembly of GlcNAc-1-phosphotransferase

Encarnação, Marisa, Kollmann, Katrin, Trusch, Maria, Braulke, Thomas, Pohl, Sandra

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.25 MB

english, 2011

74

Apoptotic Photoreceptor Loss and Altered Expression of Lysosomal Proteins in the nclf Mouse Model of Neuronal Ceroid Lipofuscinosis

Bartsch, Udo, Galliciotti, Giovanna, Jofre, Guillermo F., Jankowiak, Wanda, Hagel, Christian, Braulke, Thomas

Journal:

Investigative Opthalmology & Visual Science

Year:

2013

Language:

english

File:

PDF, 998 KB

english, 2013

75

Lrp1/LDL Receptor Play Critical Roles in Mannose 6-Phosphate-Independent Lysosomal Enzyme Targeting

Markmann, Sandra, Thelen, Melanie, Cornils, Kerstin, Schweizer, Michaela, Brocke-Ahmadinejad, Nahal, Willnow, Thomas, Heeren, Joerg, Gieselmann, Volkmar, Braulke, Thomas, Kollmann, Katrin

Journal:

Year:

2015

Language:

english

File:

PDF, 909 KB

english, 2015

76

Defective Endoplasmic Reticulum-resident Membrane Protein CLN6 Affects Lysosomal Degradation of Endocytosed Arylsulfatase A

Heine, Claudia, Koch, Bettina, Storch, Stephan, Kohlschütter, Alfried, Palmer, David N., Braulke, Thomas

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 704 KB

english, 2004

77

Interaction of Glutaric Aciduria Type 1-Related glutaryl-CoA Dehydrogenase with Mitochondrial Matrix Proteins

Schmiesing, Jessica, Schlüter, Hartmut, Ullrich, Kurt, Braulke, Thomas, Mühlhausen, Chris, Pereira, Inês A. Cardoso

Journal:

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

78

Mannose 6-phosphate receptor-dependent endocytosis of lysosomal enzymes is increased in sulfatide-storing kidney cells

Klein, Diana, Yaghootfam, Afshin, Matzner, Ullrich, Koch, Bettina, Braulke, Thomas, Gieselmann, Volkmar

Journal:

Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 245 KB

english, 2009

79

Low Temperature Blocks Transport and Sorting of Cathepsin D in Fibroblasts

BRAULKE, Thomas, HASILIK, Andrej, von FIGURA, Kurt

Journal:

Biological Chemistry Hoppe-Seyler

Year:

1988

File:

PDF, 1.79 MB

1988

80

Effects of Differentiation-Inducing Agents on Synthesis, Maturation and Secretion of Cathepsin D in U937 and HL-60 Cells

STEIN, Martin, BRAULKE, Thomas, VON FIGURA, Kurt, HASILIK, Andrej

Journal:

Biological Chemistry Hoppe-Seyler

Year:

1987

Language:

english

File:

PDF, 1.05 MB

english, 1987

81

46-kDa Mannose 6-phosphate-Specific Receptor: Biosynthesis, Processing, Subcellular Location and Topology

STEIN, Martin, BRAULKE, Thomas, KRENTLER, Christiane, HASILIK, Andrej, VON FIGURA, Kurt

Journal:

Biological Chemistry Hoppe-Seyler

Year:

1987

Language:

english

File:

PDF, 2.38 MB

english, 1987

82

Lysoplex: An efficient toolkit to detect DNA sequence variations in the autophagy-lysosomal pathway

Di Fruscio, Giuseppina, Schulz, Angela, De Cegli, Rossella, Savarese, Marco, Mutarelli, Margherita, Parenti, Giancarlo, Banfi, Sandro, Braulke, Thomas, Nigro, Vincenzo, Ballabio, Andrea

Journal:

Year:

2015

Language:

english

File:

PDF, 786 KB

english, 2015

83

Protein Kinase A Dependent Phosphorylation of Apical Membrane Antigen 1 Plays an Important Role in Erythrocyte Invasion by the Malaria Parasite

Leykauf, Kerstin, Treeck, Moritz, Gilson, Paul R., Nebl, Thomas, Braulke, Thomas, Cowman, Alan F., Gilberger, Tim W., Crabb, Brendan S., Kim, Kami

Journal:

Year:

2010

Language:

english

File:

PDF, 2.01 MB

english, 2010

84

Site-1 protease-activated formation of lysosomal targeting motifs is independent of the lipogenic transcription control

Klünder, Sarah, Heeren, Jörg, Markmann, Sandra, Santer, René, Braulke, Thomas, Pohl, Sandra

Journal:

The Journal of Lipid Research

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

85

Subunit interactions of the disease-related hexameric GlcNAc-1-phosphotransferase complex

De Pace, Raffaella, Velho, Renata Voltolini, Encarnação, Marisa, Marschner, Katrin, Braulke, Thomas, Pohl, Sandra

Journal:

Human Molecular Genetics

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

86

Proteolysis of Insulin-Like Growth Factors (IGF) and IGF Binding Proteins by Cathepsin D 1

Claussen, Max, Kübler, Bernd, Wendland, Martin, Neifer, Klaus, Schmidt, Bernhard, Zapf, Jürgen, Braulke, Thomas

Journal:

Year:

1997

Language:

english

File:

PDF, 8.00 MB

english, 1997

87

Proteolysis of Insulin-Like Growth Factor Binding Proteins by a Novel 50-Kilodalton Metalloproteinase in Human Pregnancy Serum 1

Kübler, Bernd, Cowell, Susan, Zapf, Jürgen, Braulke, Thomas

Journal:

Year:

1998

Language:

english

File:

PDF, 403 KB

english, 1998

88

Insulin-Like Growth Factor (IGF)-Binding Protein-1 Is Highly Induced during Acute Carbon Tetrachloride Liver Injury and Potentiates the IGF-I-Stimulated Activation of Rat Hepatic Stellate Cells

Scharf, Jens-Gerd, Dombrowski, Frank, Novosyadlyy, Ruslan, Eisenbach, Christoph, Demori, Ilaria, Kübler, Bernd, Braulke, Thomas

Journal:

Year:

2004

Language:

english

File:

PDF, 529 KB

english, 2004

89

Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishes N -glycan phosphorylation in a branch-specific manner

Blackler, Ryan J, Evans, Dylan W, Smith, David F, Cummings, Richard D, Brooks, Cory L, Braulke, Thomas, Liu, Xinyu, Evans, Stephen V, Müller-Loennies, Sven

Journal:

Year:

2016

Language:

english

File:

PDF, 957 KB

english, 2016

90

Mannose 6-phosphate-dependent targeting of lysosomal enzymes is required for normal craniofacial and dental development

Koehne, Till, Markmann, Sandra, Schweizer, Michaela, Muschol, Nicole, Friedrich, Reinhard E., Hagel, Christian, Glatzel, Markus, Kahl-Nieke, Bärbel, Amling, Michael, Schinke, Thorsten, Braulke, Thomas

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2016

Language:

english

File:

PDF, 4.21 MB

english, 2016

91

Frequency of del(12p) is commonly underestimated in myelodysplastic syndromes: Results from a German diagnostic study in comparison with an international control group

Braulke, Friederike, Müller-Thomas, Catharina, Götze, Katharina, Platzbecker, Uwe, Germing, Ulrich, Hofmann, Wolf-Karsten, Giagounidis, Aristoteles A. N., Lübbert, Michael, Greenberg, Peter L., Bennet

Journal:

Genes, Chromosomes and Cancer

Year:

2015

Language:

english

File:

PDF, 136 KB

english, 2015

92

Mannose 6-phosphate-independent Lysosomal Sorting of LIMP-2

Blanz, Judith, Zunke, Friederike, Markmann, Sandra, Damme, Markus, Braulke, Thomas, Saftig, Paul, Schwake, Michael

Journal:

Year:

2015

Language:

english

File:

PDF, 3.69 MB

english, 2015

93

Enhanced expression of manganese-dependent superoxide dismutase in human and sheep CLN6 tissues

HEINE, Claudia, TYYNELÄ, Jaana, COOPER, Jonathan D., PALMER, David N., ELLEDER, Milan, KOHLSCHÜTTER, Alfried, BRAULKE, Thomas

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 272 KB

english, 2003

94

Secretion of phosphomannosyl-deficient arylsulphatase A and cathepsin D from isolated human macrophages

MUSCHOL, Nicole, MATZNER, Ulrich, TIEDE, Stephan, GIESELMANN, Volkmar, ULLRICH, Kurt, BRAULKE, Thomas

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 321 KB

english, 2002

95

A replacement of the active-site aspartic acid residue 293 in mouse cathepsin D affects its intracellular stability, processing and transport in HEK-293 cells

PARTANEN, Sanna, STORCH, Stephan, LÖFFLER, Hans-Gerhard, HASILIK, Andrej, TYYNELÄ, Jaana, BRAULKE, Thomas

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 305 KB

english, 2003

96

Mannose 6-phosphate specific receptors: structure and function

POHLMANN, REGINA, NAGEL, GERHARD, HILLE, ANNETTE, WENDLAND, MARTIN, WAHEED, ABDUL, BRAULKE, THOMAS, VON FIGURA, KURT

Journal:

Biochemical Society Transactions

Year:

1989

Language:

english

File:

PDF, 266 KB

english, 1989

97

Identification of the interaction domains between α- and γ-subunits of GlcNAc-1-phosphotransferase

Velho, Renata Voltolini, De Pace, Raffaella, Tidow, Henning, Braulke, Thomas, Pohl, Sandra

Journal:

Year:

2016

Language:

english

File:

PDF, 1020 KB

english, 2016

98

Disease-causing mutations affecting surface residues of mitochondrial glutaryl-CoA dehydrogenase impair stability, heteromeric complex formation and mitochondria architecture

Schmiesing, Jessica, Lohmöller, Benjamin, Schweizer, Michaela, Tidow, Henning, Gersting, Søren W., Muntau, Ania C., Braulke, Thomas, Mühlhausen, Chris

Journal:

Human Molecular Genetics

Year:

2017

Language:

english

File:

PDF, 3.44 MB

english, 2017

99

Quantitative Proteome Analysis of Mouse Liver Lysosomes Provides Evidence for Mannose 6-phosphate-independent Targeting Mechanisms of Acid Hydrolases in Mucolipidosis II

Markmann, Sandra, Krambeck, Svenja, Hughes, Christopher J., Mirzaian, Mina, Aerts, Johannes M.F.G., Saftig, Paul, Schweizer, Michaela, Vissers, Johannes P.C., Braulke, Thomas, Damme, Markus

Journal:

Molecular & Cellular Proteomics

Year:

2017

Language:

english

File:

PDF, 1.06 MB

english, 2017

100

DEFECTIVE PROCESSING OF LYSOSOMAL ENZYMES

Von Figura, Kurt, Hasilik, Andrej, Pohlmann, Regina, Lemansky, Peter, Braulke, Thomas

Journal:

Pediatric Research

Year:

1986

Language:

english

File:

PDF, 920 KB

english, 1986

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