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51

Simulation of complex pharmacokinetic models in Microsoft EXCEL

Ingolf Meineke, Jürgen Brockmöller

Journal:

Computer Methods and Programs in Biomedicine

Year:

2007

Language:

english

File:

PDF, 1.17 MB

english, 2007

52

Anxiety- and novelty seeking-related personality traits and serotonin transporter gene polymorphisms

Stefan Viktor Vormfelde, Imke Hoell, Mladen Tzvetkov, Katja Jamrozinski, Daniel Sehrt, Jürgen Brockmöller, Eric Leibing

Journal:

Journal of Psychiatric Research

Year:

2006

Language:

english

File:

PDF, 206 KB

english, 2006

53

Corrigendum to “Anxiety- and novelty seeking-related personality traits and serotonin transporter gene polymorphisms” [J Psychiatr Res 40 (2006) 568–576]

Stefan Viktor Vormfelde, Imke Hoell, Mladen Tzvetkov, Katja Jamrozinski, Daniel Sehrt, Jürgen Brockmöller, Eric Leibing

Journal:

Journal of Psychiatric Research

Year:

2008

Language:

english

File:

PDF, 55 KB

english, 2008

54

Metabolic gene polymorphisms and lung cancer risk in non-smokers: An update of the GSEC study

Sara Raimondi, Paolo Boffetta, Sisko Anttila, Jürgen Bröckmoller, Dorota Butkiewicz, Ingolf Cascorbi, Margie L. Clapper, Tommaso A. Dragani, Seymour Garte, Andre Gsur, Gerald Haidinger, Ari Hirvonen,

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

55

Concordance between enzyme activity and genotype of glutathione S-transferase theta (GSTT1)

Claudia Bruhn, Jürgen Brockmöller, Reinhold Kerb, Ivar Roots, Hans-Hubert Borchert

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 456 KB

english, 1998

56

Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1)

Claudia Bruhn, Jürgen Brockmöller, Ingolf Cascorbi, Ivar Roots, Hans-Hubert Borchert

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 284 KB

english, 1999

57

P XVI A.8 - P XVI A.8 High benzo[a]pyrene diol-epoxide DNA adduct levels in lung and blood cells from subjects with combined CYP1A1 MspI/MspI-GSTM10/0 genotypes

Margarita Rojas, Kroum Alexandrov, Ingolf Cascorbi, Jürgen Brockmöller, Alexei Likhachev, Guy Bouvier, Guy Auburtin, Lucienne Mayer, Ivar Roots, Helmut Bartsch

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 128 KB

english, 1997

58

Identification of the N-tosyl-L-phenylalanyl chloromethylketone modification site in Thermus thermophilus elongation factor Tu

Marcus E. Peter, Jürgen Brockmöller, Jiří Jonák, Mathias Sprinzl

Journal:

Year:

1989

Language:

english

File:

PDF, 433 KB

english, 1989

59

Variations in the peroxisome proliferator-activated receptor-γ gene and melanoma risk

Rotraut Mössner, Peter Meyer, Florian Jankowski, Inke R. König, Ullrich Krüger, Stefan Kammerer, Götz Westphal, Melanie B. Boettger, Carola Berking, Christina Schmitt, Jürgen Brockmöller, Andreas Zieg

Journal:

Year:

2007

Language:

english

File:

PDF, 102 KB

english, 2007

60

Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine

Mladen Vassilev Tzvetkov, Cornelia Meineke, Elke Oetjen, Karen Hirsch-Ernst, Jürgen Brockmöller

Journal:

Year:

2007

Language:

english

File:

PDF, 865 KB

english, 2007

61

Atrial natriuretic peptide polymorphisms, hydrochlorothiazide and urinary potassium excretion

Stefan Viktor Vormfelde, Mohammad Reza Toliat, Peter Nürnberg, Jürgen Brockmöller

Journal:

International Journal of Cardiology

Year:

2010

Language:

english

File:

PDF, 111 KB

english, 2010

62

Can extremely low or high morphine formation from codeine be predicted prior to therapy initiation?

Jörn Lötsch, Maren Rohrbacher, Helmut Schmidt, Alexandra Doehring, Jürgen Brockmöller, Gerd Geisslinger

Journal:

Year:

2009

Language:

english

File:

PDF, 281 KB

english, 2009

63

Phenocopies of poor metabolizers of omeprazole caused by liver disease and drug treatment

Karl Ludwig Rost, Jürgen Brockmöller, Friederike Esdorn, Ivar Roots

Journal:

Journal of Hepatology

Year:

1995

Language:

english

File:

PDF, 894 KB

english, 1995

64

Impact ofUGT2B7His268Tyrpolymorphism on the outcome of adjuvant epirubicin treatment in breast cancer

Sumit Parmar, Carolin Julia Stingl, Ariana Huber-Wechselberger, Alexander Kainz, Wilfried Renner, Uwe Langsenlehner, Peter Krippl, Jürgen Brockmöller, Elisabeth Haschke-Becher

Journal:

Breast Cancer Research

Year:

2011

Language:

english

File:

PDF, 406 KB

english, 2011

65

Pharmacogenetic analyses of cisplatin-induced nephrotoxicity indicate a renoprotective effect of ERCC1 polymorphisms

Tzvetkov, Mladen V, Behrens, Gerrit, O’Brien, Valerie P, Hohloch, Karin, Brockmöller, Jürgen, Benöhr, Peter

Journal:

Pharmacogenomics

Year:

2011

Language:

english

File:

PDF, 873 KB

english, 2011

66

Cu,Zn SOD in German families with ALS

Rainer Bachus, Annett Claus, Dirk Megow, Jürgen Brockmöller, Tomas Porstmann, Christian A. Gericke, Matthias Riepe, Gerald Küther, Stefan Zierz, Albert C. Ludolph

Journal:

Journal of the Neurological Sciences

Year:

1995

Language:

english

File:

PDF, 266 KB

english, 1995

67

Polymorphisms in xenobiotic conjugation and disease predisposition

Jürgen Brockmöller, Ingolf Cascorbi, Reinhold Kerb, Christoph Sachse, Ivar Roots

Journal:

Toxicology Letters

Year:

1998

Language:

english

File:

PDF, 232 KB

english, 1998

68

Frequency of the 17-bp variable number of tandem repeat polymorphism in Turkish schizophrenic patients

Hasan Herken, M Emin Erdal, A Şükrü Aynacıoǧlu, Ömer Barlas, Osman Cataloluk, Koray Esgi, Jurgen Brockmöller, Rolf Kaiser

Journal:

Schizophrenia Research

Year:

2002

Language:

english

File:

PDF, 63 KB

english, 2002

69

Influence of CYP2C9 and CYP2D6 Polymorphisms on the Pharmacokinetics of Nateglinide in Genotyped Healthy Volunteers

Dr Julia Kirchheiner, Ingolf Meineke, Göran Müller, Steffen Bauer, Wolfgang Rohde, Christian Meisel, Ivar Roots, Jürgen Brockmöller

Journal:

Clinical Pharmacokinetics

Year:

2004

Language:

english

File:

PDF, 178 KB

english, 2004

70

Effect of Genetic Polymorphisms in Cytochrome P450 (CYP) 2C9 and CYP2C8 on the Pharmacokinetics of Oral Antidiabetic Drugs

Dr Julia Kirchheiner, Ivar Roots, Mark Goldammer, Bernd Rosenkranz, Jürgen Brockmöller

Journal:

Clinical Pharmacokinetics

Year:

2005

Language:

english

File:

PDF, 197 KB

english, 2005

71

Halogenated volatile anesthetics alter brain metabolism as revealed by proton magnetic resonance spectroscopy of mice in vivo

Boretius, Susann, Tammer, Roland, Michaelis, Thomas, Brockmöller, Jürgen, Frahm, Jens

Journal:

Year:

2013

Language:

english

File:

PDF, 1.85 MB

english, 2013

72

Prediction of Aryl Hydrocarbon Receptor-Mediated Enzyme Induction of Drugs and Chemicals by mRNA Quantification

Frötschl, Roland, Chichmanov, Lubomir, Kleeberg, Ullrich, Hildebrandt, Alfred G., Roots, Ivar, Brockmöller, Jürgen

Journal:

Chemical Research in Toxicology

Year:

1998

Language:

english

File:

PDF, 159 KB

english, 1998

73

Morphine is a substrate of the organic cation transporter OCT1 and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administration

Tzvetkov, Mladen V., dos Santos Pereira, Joao N., Meineke, Ingolf, Saadatmand, Ali R., Stingl, Julia C., Brockmöller, Jürgen

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.68 MB

english, 2013

74

Genetic Polymorphisms in 11β-Hydroxysteroid Dehydrogenase Type 1 Correlate With the Postdexamethasone Cortisol Levels and Bone Mineral Density in Patients Evaluated for Osteoporosis

Siggelkow, Heide, Etmanski, Michael, Bozkurt, Sarayi, Groβ, Parissa, Koepp, Regine, Brockmöller, Jürgen, Tzvetkov, Mladen V.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2014

Language:

english

File:

PDF, 934 KB

english, 2014

75

CYCLOSPORIN METABOLITES AND CENTRAL-NERVOUS-SYSTEM TOXICITY

Kunzendorf, Ulrich, Brockmöller, Jürgen, Jochimsen, Friederike, Keller, Frieder, Walz, Gerd, Offermann, Gerd

Journal:

Year:

1988

Language:

english

File:

PDF, 137 KB

english, 1988

76

IMMUNOSUPPRESSIVE PROPERTIES OF CYCLOSPORIN METABOLITES

Kunzendorf, Ulrich, Brockmöller, Jürgen, Jochimsen, Friederike, Roots, Ivar, Offermann, Gerd

Journal:

Year:

1989

Language:

english

File:

PDF, 314 KB

english, 1989

77

Carvedilol pharmacokinetics and pharmacodynamics in relation to CYP2D6 and ADRB pharmacogenetics

Sehrt, Daniel, Meineke, Ingolf, Tzvetkov, Mladen, Gültepe, Senol, Brockmöller, Jürgen

Journal:

Pharmacogenomics

Year:

2011

Language:

english

File:

PDF, 871 KB

english, 2011

78

Dominant Contribution of P450 3A4 to the Hepatic Carcinogenic Activation of Aflatoxin B 1

Kamdem, Landry K., Meineke, Ingolf, Gödtel-Armbrust, Ute, Brockmöller, Jürgen, Wojnowski, Leszek

Journal:

Chemical Research in Toxicology

Year:

2006

Language:

english

File:

PDF, 182 KB

english, 2006

79

Impact of CYP2D6*4 genotype on progression free survival in tamoxifen breast cancer treatment

Stingl, Julia Carolin, Parmar, Sumit, Huber-Wechselberger, Ariana, Kainz, Alexander, Renner, Wilfried, Seeringer, Angela, Brockmöller, Jürgen, Langsenlehner, Uwe, Krippl, Peter, Haschke-Becher, Elisab

Journal:

Current Medical Research and Opinion

Year:

2010

Language:

english

File:

PDF, 328 KB

english, 2010

80

The Poorly Membrane Permeable Antipsychotic Drugs Amisulpride and Sulpiride Are Substrates of the Organic Cation Transporters from the SLC22 Family

Dos Santos Pereira, Joao N., Tadjerpisheh, Sina, Abed, Manar Abu, Saadatmand, Ali R., Weksler, Babette, Romero, Ignacio A., Couraud, Pierre-Olivier, Brockmöller, Jürgen, Tzvetkov, Mladen V.

Journal:

The AAPS Journal

Year:

2014

Language:

english

File:

PDF, 575 KB

english, 2014

81

INDUCTION OF CYP1A BY VARIOUS BENZIMIDAZOLES AND ITS SIGNIFICANCE IN ADMINISTRATIVE DRUG REGULATION

KLEEBERG, ULLRICH, FRÖTSCHL, ROLAND, KRUSEKOPF, SOLVEIGH, BROCKMÖLLER, JÜRGEN, ROOTS, IVAR, RUCKPAUL, KLAUS, HILDEBRANDT, ALFRED G.

Journal:

Drug Metabolism Reviews

Year:

1999

Language:

english

File:

PDF, 409 KB

english, 1999

82

Influence ofGSTT1andGSTM1Genotypes on Sunburn Sensitivity

Reinhold Kerb,Jürgen Brockmöller…

Journal:

American Journal of PharmacoGenomics

Year:

2002

Language:

english

File:

PDF, 195 KB

english, 2002

83

Evaluation of Hepatic Function Using the Pharmacokinetics of a Therapeutically Administered Drug

Dr Willi Weber,Michael Looby,Jürgen Brockmöller

Journal:

Clinical Pharmacokinetics

Year:

1992

Language:

english

File:

PDF, 1.72 MB

english, 1992

84

Assessment of Liver Metabolic Function

Dr Jürgen Brockmöller,Roots Ivar

Journal:

Clinical Pharmacokinetics

Year:

1994

Language:

english

File:

PDF, 3.03 MB

english, 1994

85

Pharmacogenetics‐Based New Therapeutic Concepts

Roots, Ivar, Gerloff, Thomas, Meisel, Christian, Kirchheiner, Julia, Goldammer, Mark, Kaiser, Rolf, Laschinski, Gabriele, Brockmöller, Jürgen, Cascorbi, Ingolf, Kleeberg, Ullrich, Hildebrandt, Alfred

Journal:

Drug Metabolism Reviews

Year:

2004

Language:

english

File:

PDF, 512 KB

english, 2004

86

Genetic variants in FKBP5 affecting response to antidepressant drug treatment

Kirchheiner, Julia, Lorch, Rainer, Lebedeva, Elena, Seeringer, Angela, Roots, Ivar, Sasse, Johanna, Brockmöller, Jürgen

Journal:

Pharmacogenomics

Year:

2008

Language:

english

File:

PDF, 193 KB

english, 2008

87

Pharmacogenetic diagnostics of cytochrome P450 polymorphisms in clinical drug development and in drug treatment

Brockmöller, Jürgen, Kirchheiner, Julia, Meisel, Christian, Roots, Ivar

Journal:

Pharmacogenomics

Year:

2000

Language:

english

File:

PDF, 252 KB

english, 2000

88

Impact of genetic polymorphisms in CYP2C8 and rosiglitazone intake on the urinary excretion of dihydroxyeicosatrienoic acids

Kirchheiner, Julia, Meineke, Ingolf, Fuhr, Uwe, Rodríguez-Antona, Cristina, Lebedeva, Elena, Brockmöller, Jürgen

Journal:

Pharmacogenomics

Year:

2008

Language:

english

File:

PDF, 360 KB

english, 2008

89

CYP2D6 und Tamoxifen: pharmakogenetische Neuentdeckung eines etablierten Medikaments? / CYP2D6 and tamoxifen: pharmacogenetic reinvention of an established drug?

von Ahsen, Nicolas, Binder, Claudia, Brockmöller, Jürgen, Oellerich, Michael

Journal:

Laboratoriums Medizin

Year:

2009

File:

PDF, 240 KB

2009

90

Routine Micromethod for the Determination of Vitamin K1 in Human Plasma

Meineke, Ingolf, Willnow, Cornelia, Stingl, Julia, Brockmöller, Jürgen

Journal:

Therapeutic Drug Monitoring

Year:

2013

Language:

english

File:

PDF, 239 KB

english, 2013

91

Isolation and Identification of Two Protein-Protein Crosslinks within the Two Subunits of Bacillus stearothermophilus Ribosomes

BROCKMÖLLER, Jürgen, KAMP, Roza Maria

Journal:

Biological Chemistry Hoppe-Seyler

Year:

1986

Language:

english

File:

PDF, 2.25 MB

english, 1986

92

Two-dimensional Polyacrylamide Gel Electrophoresis of Ribosomal Proteins in the Nanogram Range

BROCKMÖLLER, Jürgen, KAMP, Roza Maria

Journal:

Biological Chemistry Hoppe-Seyler

Year:

1985

Language:

english

File:

PDF, 1.08 MB

english, 1985

93

How to Manage Individualized Drug Therapy: Application of Pharmacogenetic Knowledge of Drug Metabolism and Transport

Meisel, Christian, Roots, Ivar, Cascorbi, Ingolf, Brinkmann, Ulrich, Brockmöller, Jürgen

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2000

Language:

english

File:

PDF, 265 KB

english, 2000

94

CYP2D6 and tamoxifen: pharmacogenetic reinvention of an established drug? 1

von Ahsen, Nicolas, Binder, Claudia, Brockmöller, Jürgen, Oellerich, Michael

Journal:

Laboratoriums Medizin

Year:

2009

Language:

english

File:

PDF, 197 KB

english, 2009

95

Impact of mineralocorticoid receptor polymorphisms on urinary electrolyte excretion with and without diuretic drugs

Dalila, Nawar, Brockmöller, Jürgen, Tzvetkov, Mladen Vassilev, Schirmer, Markus, Haubrock, Martin, Vormfelde, Stefan Viktor

Journal:

Pharmacogenomics

Year:

2015

Language:

english

File:

PDF, 1.61 MB

english, 2015

96

Polymorphic OCT1 : a valid biomarker, but for which drugs?

Brockmöller, Jürgen, Tzvetkov, Mladen V

Journal:

Pharmacogenomics

Year:

2013

Language:

english

File:

PDF, 908 KB

english, 2013

97

Amelogenin-based sex identification as a strategy to control the identity of DNA samples in genetic association studies

Tzvetkov, Mladen Vassilev, Meineke, Ingolf, Sehrt, Daniel, Vormfelde, Stefan Viktor, Brockmöller, Jürgen

Journal:

Pharmacogenomics

Year:

2010

Language:

english

File:

PDF, 1.49 MB

english, 2010

98

Patients’ and physicians’ perspectives on pharmacogenetic testing

Rogausch, Anja, Prause, Daniela, Schallenberg, Anne, Brockmöller, Jürgen, Himmel, Wolfgang

Journal:

Pharmacogenomics

Year:

2006

Language:

english

File:

PDF, 425 KB

english, 2006

99

Erratum to: Evaluation of Hepatic Function Using the Pharmacokinetics of a Therapeutically Administered Drug

Weber, Willi, Looby, Michael, Brockmöller, Jürgen

Journal:

Clinical Pharmacokinetics

Year:

1992

Language:

english

File:

PDF, 147 KB

english, 1992

100

Neue Perspektiven in der Behandlung des nicht kleinzelligen Lungenkarzinoms (NSCLC)

Brockmöller, Jürgen, Junker, Klaus, Multhoff, Gabriele

Journal:

Year:

2006

Language:

german

File:

PDF, 227 KB

german, 2006

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