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51

Inhibition of 2,3-oxidosqualene cyclase and sterol biosynthesis by 10- and 19-azasqualene derivatives

Franca Viola, Paola Brusa, Gianni Balliano, Maurizio Ceruti, Olivier Boutaud, Francis Schuber, Luigi Cattel

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.06 MB

english, 1995

52

Differential inhibition of fungal oxidosqualene cyclase by 6E and 6Z isomers of 2,3-epoxy-10-aza-10,11-dihydrosqualene

Gianni Balliano, Paola Milla, Maurizio Ceruti, Franca Viola, Lùcia Carrano, Luigi Cattel

Journal:

Year:

1993

Language:

english

File:

PDF, 380 KB

english, 1993

53

Active site titration of bovine β-trypsin by Nα-(N,N-dimethylcarbamoyl)-α-aza-lysine p-nitrophenyl ester: kinetic and crystallographic analysis

Patrizia Sartori, Kristina Djinovic Carugo, Raffaella Ferraccioli, Gianni Balliano, Paola Milla, Paolo Ascenzi, Martino Bolognesi

Journal:

Year:

1995

Language:

english

File:

PDF, 459 KB

english, 1995

54

Drug design based on biosynthetic studies: Synthesis, biological activity, and kinetics of new inhibitors of 2,3-oxidosqualene cyclase and squalene epoxidase

Luigi Cattel, Maurizio Ceruti, Gianni Balliano, Franca Viola, Giorgio Grosa, Francis Schuber

Journal:

Year:

1989

Language:

english

File:

PDF, 1.20 MB

english, 1989

55

Genetic analyses involving interactions between the ergosterol biosynthetic enzymes, lanosterol synthase (Erg7p) and 3-ketoreductase (Erg27p), in the yeast Saccharomyces cerevisiae

B. Teske, S. Taramino, M.S.A. Bhuiyan, N.S. Kumaraswami, S.K. Randall, R. Barbuch, J. Eckstein, G. Balliano, M. Bard

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2008

Language:

english

File:

PDF, 2.04 MB

english, 2008

56

Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast

S. Taramino, M. Valachovic, S. Oliaro-Bosso, F. Viola, B. Teske, M. Bard, G. Balliano

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 572 KB

english, 2010

57

Divergent interactions involving the oxidosqualene cyclase and the steroid-3-ketoreductase in the sterol biosynthetic pathway of mammals and yeasts

Silvia Taramino, Brian Teske, Simonetta Oliaro-Bosso, Martin Bard, Gianni Balliano

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 360 KB

english, 2010

58

In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity

C. Mo, P. Milla, K. Athenstaedt, R. Ott, G. Balliano, G. Daum, M. Bard

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2003

Language:

english

File:

PDF, 451 KB

english, 2003

59

Metabolism of glucose-6-phosphate in slices of rat brain cortex

Marta Balliano, Ines Masi, Francesco Pocchiari

Journal:

Year:

1969

Language:

english

File:

PDF, 165 KB

english, 1969

60

Characterization of a mutation that results in independence of oxidosqualene cyclase (Erg7) activity from the downstream 3-ketoreductase (Erg27) in the yeast ergosterol biosynthetic pathway

Jacob V. Layer, Brett M. Barnes, Yuji Yamasaki, Robert Barbuch, Liangtao Li, Silvia Taramino, Gianni Balliano, Martin Bard

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2013

Language:

english

File:

PDF, 1.74 MB

english, 2013

61

Synthesis in Water and Antimicrobial Activity of 5-Trichloromethyl-4,5-dihydroisoxazoles

Flores, Alex F. C., Piovesan, Luciana A., Souto, Alynne A., Pereira, Mariano A., Martins, Marcos A. P., Balliano, Tatiane L., da Silva, Givanildo S.

Journal:

Synthetic Communications

Year:

2013

Language:

english

File:

PDF, 1.27 MB

english, 2013

62

2,3-Epoxy-10-aza-10,11-dihydrosqualene, a high-energy intermediate analog inhibitor of 2,3-oxidosqualene cyclase

Ceruti, Maurizio, Balliano, Gianni, Viola, Franca, Grosa, Giorgio, Rocco, Flavio, Cattel, Luigi

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.24 MB

english, 1992

63

Conversion of Squalene to the Pentacarbocyclic Hopene

REINERT, D, BALLIANO, G, SCHULZ, G

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 337 KB

english, 2004

64

Aminopropylindenes derived from Grundmann's ketone as a novel chemotype of oxidosqualene cyclase inhibitors

Lange, Stefanie, Keller, Marco, Müller, Christoph, Oliaro-Bosso, Simonetta, Balliano, Gianni, Bracher, Franz

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 388 KB

english, 2013

65

Influence of iron on oxidation of reduced nicotinamide- adenine-dinucleotide phosphate in rat-liver microsomes

Beloff-Chain, Anne, Serlupi-Crescenzi, G., Catanzaro, Raffaella, Venettacci, Domenica, Balliano, Marta

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1965

Language:

english

File:

PDF, 336 KB

english, 1965

66

29-Methylidene-2,3-oxidosqualene Derivatives as Stereospecific Mechanism-Based Inhibitors of Liver and Yeast Oxidosqualene Cyclase

Ceruti, Maurizio, Rocco, Flavio, Viola, Franca, Balliano, Gianni, Milla, Paola, Arpicco, Silvia, Cattel, Luigi

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 311 KB

english, 1998

67

Inhibition of higher plant 2,3-oxidosqualene cyclase by 2-aza-2,3-dihydrosqualene and its derivatives

Delprino, Laura, Balliano, Gianni, Cattel, Luigi, Benveniste, Pierre, Bouvier, Pierrette

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1983

Language:

english

File:

PDF, 182 KB

english, 1983

68

Synthesis of (E)- and (Z)-29-methylidyne-2,3-oxidosqualene derivatives as inhibitors of liver and yeast oxidosqualene cyclase

Ceruti, Maurizio, Viola, Franca, Balliano, Gianni, Milla, Paola, Roma, Giorgio, Grossi, Giancarlo, Rocco, Flavio

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2002

Language:

english

File:

PDF, 241 KB

english, 2002

69

Umbelliferone aminoalkyl derivatives as inhibitors of human oxidosqualene-lanosterol cyclase

Oliaro-Bosso, Simonetta, Taramino, Silvia, Viola, Franca, Tagliapietra, Silvia, Ermondi, Giuseppe, Cravotto, Giancarlo, Balliano, Gianni

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 382 KB

english, 2009

70

Potential Avoidance of Adverse Analgesic Effects Using a Biologically “Smart” Hydrogel Capable of Controlled Bupivacaine Release

Taraballi, Francesca, Minardi, Silvia, Corradetti, Bruna, Yazdi, Iman K, Balliano, Marta A, Van Eps, Jeffrey L, Allegri, Massimo, Tasciotti, Ennio

Journal:

Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 931 KB

english, 2014

71

Inhibition of sterol biosynthesis in Saccharomyces cerevisiae and Candida albicans by 22,23-epoxy-2-aza-2,3-dihydrosqualene and the corresponding N-oxide.

Balliano, G, Milla, P, Ceruti, M, Carrano, L, Viola, F, Brusa, P, Cattel, L

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1994

Language:

english

File:

PDF, 954 KB

english, 1994

72

Yeast Oxidosqualene Cyclase (Erg7p) Is a Major Component of Lipid Particles

Milla, P., Athenstaedt, K., Viola, F., Oliaro-Bosso, S., Kohlwein, S. D., Daum, G., Balliano, G.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 609 KB

english, 2002

73

1,2-Dihydroxy-2-(3-methylbut-2-enyl)-3-oxo-2,3-dihydro-1 H -indene-1-carboxylic acid monohydrate

Franscisco, Acácio Ivo, Silveira, Gleiciani de Q., Resende, Jackson A. L. C., Balliano, Tatiane L., Malta, Valéria R. S., Pinto, Antonio Ventura

Journal:

Acta Crystallographica Section E Structure Reports Online

Year:

2010

Language:

english

File:

PDF, 563 KB

english, 2010

74

The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination

Maione, Federica, Oliaro-Bosso, Simonetta, Meda, Claudia, Di Nicolantonio, Federica, Bussolino, Federico, Balliano, Gianni, Viola, Franca, Giraudo, Enrico

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 2.38 MB

english, 2015

75

The Mechanism of Alkylation at C-24 During the C 29 Sterol Biosynthesis in Cucurbita maxima Seedlings

Cattel, L., Balliano, G., Viola, F., Caputo, O.

Journal:

Year:

1980

Language:

english

File:

PDF, 1.09 MB

english, 1980

76

Biosynthesis of Cucurbitacins inBryonia dioicaSeedlings

L. Cattel, G. Balliano, O. Caputo, F. Viola

Year:

1981

Language:

english

File:

PDF, 426 KB

english, 1981

77

Biosynthesis of Sterols and Triterpenoids in Tissue Cultures of Cucurbita maxima

Caputo, O., Delprino, L., Viola, F., Caramiello, R., Balliano, G.

Journal:

Year:

1983

Language:

english

File:

PDF, 382 KB

english, 1983

78

Base excision repair in chromatin: Insights from reconstituted systems

Balliano, Angela J., Hayes, Jeffrey J.

Journal:

Year:

2015

Language:

english

File:

PDF, 646 KB

english, 2015

79

Arylpiperidines as a new class of oxidosqualene cyclase inhibitors

Keller, Marco, Wolfgardt, Annette, Müller, Christoph, Wilcken, Rainer, Böckler, Frank M., Oliaro-Bosso, Simonetta, Ferrante, Terenzio, Balliano, Gianni, Bracher, Franz

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1021 KB

english, 2016

80

ChemInform Abstract: Synthesis of a Squalenoid Oxaziridine and Other New Classes of Squalene Derivatives, as Inhibitors of Sterol Biosynthesis.

CERUTI, M., VIOLA, F., BALLIANO, G., GROSA, G., CAPUTO, O., GERST, N., SCHUBER, F., CATTEL, L.

Journal:

Year:

1989

File:

PDF, 183 KB

1989

81

ChemInform Abstract: Synthesis in Water and Antimicrobial Activity of 5-Trichloromethyl-4,5-dihydroisoxazoles.

Flores, Alex F., Piovesan, Luciana A., Souto, Alynne A., Pereira, Mariano A., Martins, Marcos A. P., Balliano, Tatiane L., Da Silva, Givanildo S.

Journal:

Year:

2013

File:

PDF, 31 KB

2013

82

4-Methylzymosterone and Other Intermediates of Sterol Biosynthesis from Yeast Mutants Engineered in theERG27Gene Encoding 3-Ketosteroid Reductase

Ferrante, Terenzio, Barge, Alessandro, Taramino, Silvia, Oliaro-Bosso, Simonetta, Balliano, Gianni

Journal:

Year:

2016

Language:

english

File:

PDF, 536 KB

english, 2016

83

Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies

Oliaro-Bosso, S., Schulz-Gasch, T., Taramino, S., Scaldaferri, M., Viola, F., Balliano, G.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 207 KB

english, 2005

84

Access of the substrate to the active site of squalene and oxidosqualene cyclases: comparative inhibition, site-directed mutagenesis and homology-modelling studies

Oliaro-Bosso, S., Schulz-Gasch, T., Taramino, S., Scaldaferri, M., Viola, F., Balliano, G.

Journal:

Biochemical Society Transactions

Year:

2005

Language:

english

File:

PDF, 207 KB

english, 2005

85

Novel Squalene-Hopene Cyclase Inhibitors Derived from Hydroxycoumarins and Hydroxyacetophenones

Cravotto, Giancarlo, Balliano, Gianni, Tagliapietra, Silvia, Oliaro-Bosso, Simonetta, Nano, Gian Mario

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2004

Language:

english

File:

PDF, 128 KB

english, 2004

86

HMGB1 Stimulates Activity of Polymerase β on Nucleosome Substrates

Balliano, Angela, Hao, Fanfan, Njeri, Catherine, Balakrishnan, Lata, Hayes, Jeffrey J.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.59 MB

english, 2017

87

ChemInform Abstract: BROMINATION OF 3-ACYL-4-HYDROXY-6-METHYL-2H-THIOPYRAN-2-ONES. II

CAPUTO, O., VIOLA, F., BALLIANO, G., BIGLINO, G.

Journal:

Chemischer Informationsdienst

Year:

1982

File:

PDF, 215 KB

1982

88

Synthesis, Structure, and Cyclocondensation of the 4,4,4-Trifluoro-3,3-dihydroxy-2-methyl-1-(thien-2-yl)-1-butanone with Hydroxylamine and Hydrazine

Flores, Alex F. C., Kuhn, Bruna P., Flores, Darlene C., Pereira, Mariano A., Balliano, Tatiane L., da Silva, Givanildo S.

Journal:

Journal of Spectroscopy

Year:

2018

Language:

english

File:

PDF, 2.19 MB

english, 2018

89

Difference in the late ergosterol biosynthesis between yeast spheroplasts and intact cells

Ferrante, Terenzio, Viola, Franca, Balliano, Gianni, Oliaro-Bosso, Simonetta

Journal:

Acta Biochimica Polonica

Year:

2016

Language:

english

File:

PDF, 343 KB

english, 2016

90

Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae

Cirigliano, Angela, Macone, Alberto, Bianchi, Michele Maria, Oliaro-Bosso, Simonetta, Balliano, Gianni, Negri, Rodolfo, Rinaldi, Teresa

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2018

Language:

english

File:

PDF, 2.27 MB

english, 2018

91

Crystal structure of 1-(2-bromoethyl)-2-methyl-5-nitroimidazole, C6H8BrN3O2

Balliano, T. L., Pereira, M. A., De Simone, C. A., Malta, V. R. S., Velasquez, N., Cioletti, A. G., Goulart, M. O. F.

Journal:

Zeitschrift für Kristallographie - New Crystal Structures

Year:

2006

Language:

english

File:

PDF, 142 KB

english, 2006

92

Multiple catalytic activities of human 17β-hydroxysteroid dehydrogenase type 7 respond differently to inhibitors

Ferrante, Terenzio, Adinolfi, Salvatore, D’Arrigo, Giulia, Poirier, Donald, Daga, Martina, Lolli, Marco Lucio, Balliano, Gianni, Spyrakis, Francesca, Oliaro-Bosso, Simonetta

Journal:

Year:

2019

File:

PDF, 12.40 MB

2019

93

Caffeine removal using activated biochar from aÃ§aÃ seed (Euterpe oleracea Mart): experimental study and description of adsorbate properties using Density Functional Theory (DFT)

da Silva Vasconcelos de Almeida, Arthur, Vieira, Wedja TimÃ³teo, Bispo, Mozart Daltro, de Melo, Samara Farias, da Silva, Thiago Lopes, Balliano, Tatiane Luciano, Vieira, Melissa Gurgel Adeodato, Solet

Journal:

Journal of Environmental Chemical Engineering

Year:

2020

File:

PDF, 169 KB

2020

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