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1

Stereocontrolled Total Synthesis of Bengazole A: A Marine Bisoxazole Natural Product Displaying Potent Antifungal Properties

James A. Bull, Emily P. Balskus, Richard A. J. Horan, Martin Langner, Steven V. Ley

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

2

Metabolic functions of the human gut microbiota: the role of metalloenzymes

Rajakovich, Lauren J., Balskus, Emily P.

Journal:

Natural Product Reports

Year:

2019

Language:

english

File:

PDF, 5.24 MB

english, 2019

3

Total Synthesis of Potent Antifungal Marine Bisoxazole Natural Products Bengazoles A and B

James A. Bull, Emily P. Balskus, Richard A. J. Horan, Martin Langner, Steven V. Ley

Journal:

Chemistry - A European Journal

Year:

2007

Language:

english

File:

PDF, 479 KB

english, 2007

4

An Enzymatic Cyclopentyl[ b ]indole Formation Involved in Scytonemin Biosynthesis

Balskus, Emily P., Walsh, Christopher T.

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 610 KB

english, 2009

5

Investigating the Initial Steps in the Biosynthesis of Cyanobacterial Sunscreen Scytonemin

Balskus, Emily P., Walsh, Christopher T.

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 120 KB

english, 2008

6

Opportunities for merging chemical and biological synthesis

Wallace, Stephen, Balskus, Emily P

Journal:

Current Opinion in Biotechnology

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

7

Using non-enzymatic chemistry to influence microbial metabolism

Wallace, Stephen, Schultz, Erica E, Balskus, Emily P

Journal:

Current Opinion in Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

8

Interfacing Microbial Styrene Production with a Biocompatible Cyclopropanation Reaction

Wallace, Stephen, Balskus, Emily P.

Journal:

Angewandte Chemie International Edition

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

9

Designer Micelles Accelerate Flux Through Engineered Metabolism in E. coli and Support Biocompatible Chemistry

Wallace, Stephen, Balskus, Emily P.

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 2.51 MB

english, 2016

10

The Human Microbiome

Balskus, Emily P.

Journal:

ACS Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 233 KB

english, 2018

11

Engineering chemical interactions in microbial communities

Kenny, Douglas J., Balskus, Emily P.

Journal:

Chemical Society Reviews

Year:

2018

Language:

english

File:

PDF, 4.71 MB

english, 2018

12

Discovery of a Diazo-Forming Enzyme in Cremeomycin Biosynthesis

Waldman, Abraham J., Balskus, Emily P.

Journal:

Journal of Organic Chemistry

Year:

2018

Language:

english

File:

PDF, 869 KB

english, 2018

13

A glycyl radical enzyme enables hydrogen sulfide production by the human intestinal bacterium Bilophila wadsworthia

Peck, Spencer C., Denger, Karin, Burrichter, Anna, Irwin, Stephania M., Balskus, Emily P., Schleheck, David

Journal:

Proceedings of the National Academy of Sciences

Year:

2019

File:

PDF, 1.13 MB

2019

14

An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin

Ng, Tai L., Rohac, Roman, Mitchell, Andrew J., Boal, Amie K., Balskus, Emily P.

Journal:

Year:

2019

File:

PDF, 9.86 MB

2019

15

Enzymes that detoxify marine toxins

McCallum, Monica E., Balskus, Emily P.

Journal:

Year:

2019

Language:

english

File:

PDF, 186 KB

english, 2019

16

Enzymes that detoxify marine toxins

McCallum, Monica E., Balskus, Emily P.

Journal:

Year:

2019

File:

PDF, 186 KB

2019

17

Cholesterol Metabolism by Uncultured Human Gut Bacteria Influences Host Cholesterol Level

Kenny, Douglas J., Plichta, Damian R., Shungin, Dmitry, Koppel, Nitzan, Hall, A. Brantley, Fu, Beverly, Vasan, Ramachandran S., Shaw, Stanley Y., Vlamakis, Hera, Balskus, Emily P., Xavier, Ramnik J.

Journal:

Cell Host & Microbe

Year:

2020

File:

PDF, 3.65 MB

2020

18

Stereocontrolled Total Synthesis of Bengazole A: A Marine Bisoxazole Natural Product Displaying Potent Antifungal Properties

James A. Bull, Emily P. Balskus, Richard A. J. Horan, Martin Langner, Steven V. Ley

Journal:

Angewandte Chemie

Year:

2006

Language:

english

File:

PDF, 126 KB

english, 2006

19

ChemInform Abstract: Intercalation of Multiple Carbon Atoms Between the Carbonyls of α-Diketones.

Emily P. Balskus, Jose Mendez-Andino, Ruslan M. Arbit, Leo A. Paquette

Journal:

Year:

2002

File:

PDF, 38 KB

2002

20

Synthetic Studies Toward Hennoxazole A. Use of a Selective Bisoxazole Alkylation as the Key Fragment Coupling.

Thomas E. Smith, Emily P. Balskus

Journal:

Year:

2002

File:

PDF, 30 KB

2002

21

A Sequential Tetra-n-propylammonium Perruthenate (TPAP)—Wittig Oxidation Olefination Protocol.

Rachel N. MacCoss, Emily P. Balskus, Steven V. Ley

Journal:

Year:

2004

File:

PDF, 169 KB

2004

22

Rhodium-Catalyzed Coupling of Heterocycles and Alkenes: A Novel Mechanism of C—H Activation

Emily P. Balskus, Steven V. Ley

Journal:

Year:

2004

File:

PDF, 51 KB

2004

23

A sequential tetra-n-propylammonium perruthenate (TPAP)–Wittig oxidation olefination protocol

Rachel N. MacCoss, Emily P. Balskus, Steven V. Ley

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 89 KB

english, 2003

24

The biosynthesis of cyanobacterial sunscreen scytonemin in intertidal microbial mat communities

Emily P. Balskus, Rebecca J. Case, Christopher T. Walsh

Journal:

FEMS Microbiology Ecology

Year:

2011

Language:

english

File:

PDF, 953 KB

english, 2011

25

Spin-transition behaviour in chains of FeII bridged by 4-substituted 1,2,4-triazoles carrying alkyl tails

Roubeau, Olivier, Alcazar Gomez, Jose´ M., Balskus, Emily, Kolnaar, Jeroen J. A., Haasnoot, Jaap G., Reedijk, Jan

Journal:

New Journal of Chemistry

Year:

2001

Language:

english

File:

PDF, 177 KB

english, 2001

26

A Prodrug Resistance Mechanism Is Involved in Colibactin Biosynthesis and Cytotoxicity

Brotherton, Carolyn A., Balskus, Emily P.

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

27

α,β-Unsaturated β-Silyl Imide Substrates for Catalytic, Enantioselective Conjugate Additions: A Total Synthesis of (+)-Lactacystin and the Discovery of a New Proteasome Inhibitor

Balskus, Emily P., Jacobsen, Eric N.

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 79 KB

english, 2006

28

Structural Analysis of Spiro β-Lactone Proteasome Inhibitors

Groll, Michael, Balskus, Emily P., Jacobsen, Eric N.

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 734 KB

english, 2008

29

Cylindrocyclophane Biosynthesis Involves Functionalization of an Unactivated Carbon Center

Nakamura, Hitomi, Hamer, Hilary A., Sirasani, Gopal, Balskus, Emily P.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

30

Rescuing Auxotrophic Microorganisms with Nonenzymatic Chemistry

Lee, Yunmi, Umeano, Afoma, Balskus, Emily P.

Journal:

Angewandte Chemie International Edition

Year:

2013

Language:

english

File:

PDF, 987 KB

english, 2013

31

Lomaiviticin Biosynthesis Employs a New Strategy for Starter Unit Generation

Waldman, Abraham J., Balskus, Emily P.

Journal:

Organic Letters

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

32

A Biocompatible Alkene Hydrogenation Merges Organic Synthesis with Microbial Metabolism

Sirasani, Gopal, Tong, Liuchuan, Balskus, Emily P.

Journal:

Angewandte Chemie International Edition

Year:

2014

Language:

english

File:

PDF, 1023 KB

english, 2014

33

A Biocompatible Alkene Hydrogenation Merges Organic Synthesis with Microbial Metabolism

Sirasani, Gopal, Tong, Liuchuan, Balskus, Emily P.

Journal:

Angewandte Chemie

Year:

2014

Language:

english

File:

PDF, 1019 KB

english, 2014

34

Natural products: Sponge symbionts play defense

Balskus, Emily P

Journal:

Nature Chemical Biology

Year:

2014

Language:

english

File:

PDF, 287 KB

english, 2014

35

Total Synthesis of (−)-Hennoxazole A

Smith, Thomas E., Kuo, Wen-Hsin, Bock, Victoria D., Roizen, Jennifer L., Balskus, Emily P., Theberge, Ashleigh B.

Journal:

Organic Letters

Year:

2007

Language:

english

File:

PDF, 80 KB

english, 2007

36

Characterization of Choline Trimethylamine-Lyase Expands the Chemistry of Glycyl Radical Enzymes

Craciun, Smaranda, Marks, Jonathan A., Balskus, Emily P.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 920 KB

english, 2014

37

Intercalation of Multiple Car-bon Atoms between the Carbonyls of α-Diketones.

Balskus, Emily P., Méndez-Andino, José, Arbit, Ruslan M., Paquette, Leo A.

Journal:

Journal of Organic Chemistry

Year:

2001

File:

PDF, 8 KB

2001

38

Total Synthesis of (−)-Hennoxazole A

Smith, Thomas E., Kuo, Wen-Hsin, Balskus, Emily P., Bock, Victoria D., Roizen, Jennifer L., Theberge, Ashleigh B., Carroll, Kathleen A., Kurihara, Tomoki, Wessler, Jeffrey D.

Journal:

Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 271 KB

english, 2008

39

Intercalation of Multiple Carbon Atoms between the Carbonyls of α-Diketones

Balskus, Emily P., Méndez-Andino, José, Arbit, Ruslan M., Paquette, Leo A.

Journal:

Journal of Organic Chemistry

Year:

2001

Language:

english

File:

PDF, 139 KB

english, 2001

40

Mechanistic insight into digoxin inactivation by Eggerthella lenta augments our understanding of its pharmacokinetics

Haiser, Henry J, Seim, Kristen L, Balskus, Emily P, Turnbaugh, Peter J

Journal:

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

41

Isolation of a Metabolite from the pks Island Provides Insights into Colibactin Biosynthesis and Activity

Brotherton, Carolyn A., Wilson, Matthew, Byrd, Gary, Balskus, Emily P.

Journal:

Organic Letters

Year:

2015

Language:

english

File:

PDF, 664 KB

english, 2015

42

Correction to Isolation of a Metabolite from the pks Island Provides Insights into Colibactin Biosynthesis and Activity

Brotherton, Carolyn A., Wilson, Matthew, Byrd, Gary, Balskus, Emily P.

Journal:

Organic Letters

Year:

2015

Language:

english

File:

PDF, 118 KB

english, 2015

43

Using Chemical Knowledge to Uncover New Biological Function: Discovery of the Cylindrocyclophane Biosynthetic Pathway

Nakamura, Hitomi, Balskus, Emily

Journal:

Year:

2013

Language:

english

File:

PDF, 585 KB

english, 2013

44

Characterization and Detection of a Widely Distributed Gene Cluster That Predicts Anaerobic Choline Utilization by Human Gut Bacteria

Martínez-del Campo, Ana, Bodea, Smaranda, Hamer, Hilary A., Marks, Jonathan A., Haiser, Henry J., Turnbaugh, Peter J., Balskus, Emily P.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.73 MB

english, 2015

45

Colibactin: understanding an elusive gut bacterial genotoxin

Balskus, Emily P.

Journal:

Natural Product Reports

Year:

2015

Language:

english

File:

PDF, 916 KB

english, 2015

46

Exploring and Understanding the Biochemical Diversity of the Human Microbiota

Koppel, Nitzan, Balskus, Emily P.

Journal:

Cell Chemical Biology

Year:

2016

Language:

english

File:

PDF, 1.35 MB

english, 2016

47

Characterization of Polyketide Synthase Machinery from the pks Island Facilitates Isolation of a Candidate Precolibactin

Zha, Li, Wilson, Matthew R., Brotherton, Carolyn A., Balskus, Emily P

Journal:

ACS Chemical Biology

Year:

2016

Language:

english

File:

PDF, 1.88 MB

english, 2016

48

The Plot Thickens: Diet Microbe Interactions May Modulate Thrombosis Risk

Martínez-del Campo, Ana, Romano, Kymberleigh A., Rey, Federico E., Balskus, Emily P.

Journal:

Cell Metabolism

Year:

2016

Language:

english

File:

PDF, 423 KB

english, 2016

49

Addressing Infectious Disease Challenges by Investigating Microbiomes

Balskus, Emily P.

Journal:

ACS Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 143 KB

english, 2016

50

Rescuing Auxotrophic Microorganisms with Nonenzymatic Chemistry

Lee, Yunmi, Umeano, Afoma, Balskus, Emily P.

Journal:

Angewandte Chemie

Year:

2013

Language:

english

File:

PDF, 964 KB

english, 2013