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51

Relaxin Family Peptides and Receptors in Mammalian Brain : Anatomical Insights and Diverse Functional Possibilities

Andrew L. Gundlach, Sherie Ma, Qian Sang, Pei-Juan Shen, Loretta Piccenna, Katayoun Sedaghat, Craig M. Smith, Ross A. D. Bathgate, Andrew J. Lawrence, Geoffrey W. Tregear, John D. Wade, David I. Finke

Journal:

Annals of the New York Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 247 KB

english, 2009

52

Relaxin remodels fibrotic healing following myocardial infarction

Bathgate, Ross A D, Du, Xiao-Jun, Samuel, Chrishan S, Cendrawan, Sofia, Gao, Xiao-Ming, Ming, Ziqiu, Zhao, Chongxin, Kiriazis, Helen, Xu, Qi, Tregear, Geoffrey W

Journal:

Laboratory Investigation

Year:

2011

Language:

english

File:

PDF, 852 KB

english, 2011

53

The Structure and Regulation of the Oxytocin Receptor

Richard Ivell, Tadashi Kimura, Dieter Müller, Kai Augustin, Nicole Abend, Ross Bathgate, Ralph Telgmann, Marga Balvers, Gina Tillmann, Anna-Riitta Fuchs

Journal:

Experimental Physiology

Year:

2001

Language:

english

File:

PDF, 338 KB

english, 2001

54

Studies on Soluble Ectodomain Proteins of Relaxin (LGR7) and Insulin 3 (LGR8) Receptors

YAN YAN, JIN CAI, PING FU, SHARON LAYFIELD, TANIA FERRARO, JIN KUMAGAI, SATOKO SUDO, JIAN-GUO TANG, ELENI GIANNAKIS, GEOFFREY W. TREGEAR, JOHN D. WADE, ROSS A.D. BATHGATE

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 695 KB

english, 2005

55

Localization of LGR7 (Relaxin Receptor) mRNA and Protein in Rat Forebrain: Correlation with Relaxin Binding Site Distribution

TANYA C.D. BURAZIN, KELLI J. JOHNSON, SHERIE MA, ROSS A.D. BATHGATE, GEOFFREY W. TREGEAR, ANDREW L. GUNDLACH

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 1.70 MB

english, 2005

56

Receptors for Relaxin Family Peptides

ROSS A. BATHGATE, RICHARD IVELL, BARBARA M. SANBORN, O DAVID SHERWOOD, ROGER J. SUMMERS

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 4.86 MB

english, 2005

57

The Human LGR7 Low-Density Lipoprotein Class A Module Requires Calcium for Structure

EMMA J. HOPKINS, ROSS A. BATHGATE, PAUL R. GOOLEY

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 838 KB

english, 2005

58

Localization of LGR7 Gene Expression in Adult Mouse Brain Using LGR7 Knock-out/LacZ Knock-in Mice: Correlation with LGR7 mRNA Distribution

LORETTA PICCENNA, PEI-JUAN SHEN, SHERIE MA, TANYA C. D. BURAZIN, JAN A. GOSSEN, SIETSE MOSSELMAN, ROSS A. D. BATHGATE, ANDREW L. GUNDLACH

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 2.56 MB

english, 2005

59

Signaling Pathways of the LGR7 and LGR8 Receptors Determined by Reporter Genes

MICHELLE L. HALLS, ROSS A. BATHGATE, PETER J. ROCHE, ROGER J. SUMMERS

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 428 KB

english, 2005

60

Relaxin Research in the Postgenomic Era

KAZUHIRO KAWAMURA, SATOKO SUDO, JIN KUMAGAI, MARGARETA PISARSKA, SHEAU YU TEDDY HSU, ROSS BATHGATE, JOHN WADE, AARON J. W. HSUEH

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 978 KB

english, 2005

61

Coevolution of the Relaxin-Like Peptides and Their Receptors

TRACEY N. WILKINSON, TERENCE P. SPEED, GEOFFREY W. TREGEAR, ROSS A.D. BATHGATE

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 450 KB

english, 2005

62

Signal Switching after Stimulation of LGR7 Receptors by Human Relaxin 2

MICHELLE L. HALLS, ROSS A. BATHGATE, ROGER J. SUMMERS

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 438 KB

english, 2005

63

Identification of Binding Sites with Differing Affinity and Potency for Relaxin Analogues on LGR7 and LGR8 Receptors

MICHELLE L. HALLS, ROSS A. BATHGATE, SATOKO SUDO, JIN KUMAGAI, COURTNEY P. BOND, ROGER J. SUMMERS

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 444 KB

english, 2005

64

The Relaxin Gene-Knockout Mouse: A Model of Progressive Fibrosis

CHRISHAN S. SAMUEL, CHONGXIN ZHAO, ROSS A.D. BATHGATE, XIAO-JUN DU, ROGER J. SUMMERS, EDWARD P. AMENTO, LESLEY L. WALKER, MARY MCBURNIE, LING ZHAO, GEOFFREY W. TREGEAR

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 481 KB

english, 2005

65

The Chemistry and Biology of Human Relaxin-3

GEOFFREY W. TREGEAR, ROSS A. BATHGATE, SHARON LAYFIELD, TANIA FERRARO, ANDREW GUNDLACH, SHERIE MA, FENG LIN, NICOLA F. HANSON, ROGER J. SUMMERS, JOHAN ROSENGREN, DAVID J. CRAIK, JOHN D. WADE

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 594 KB

english, 2005

66

Evolution of the Relaxin-Like Peptide Family: From Neuropeptide to Reproduction

TRACEY N. WILKINSON, TERRY P. SPEED, GEOFFREY W. TREGEAR, ROSS A.D. BATHGATE

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 424 KB

english, 2005

67

Insulin-Relaxin Family Peptide Signaling and Receptors in Mouse Brain Membranes and Neuronal Cells

STEFANIE ORTINAU, FENG LIN, JOHN D. WADE, GEOFFREY W. TREGEAR, ROSS A.D. BATHGATE, ANDREW L. GUNDLACH

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 433 KB

english, 2005

68

Responses of GPCR135 to Human Gene 3 (H3) Relaxin in CHO-K1 Cells Determined by Microphysiometry

EMMA T. VAN DER WESTHUIZEN, PATRICK M. SEXTON, ROSS A. D. BATHGATE, ROGER J. SUMMERS

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 462 KB

english, 2005

69

Restricted Expression of LGR8 in Intralaminar Thalamic Nuclei of Rat Brain Suggests a Role in Sensorimotor Systems

PEI-JUAN SHEN, PING FU, KEVIN D. PHELAN, DANIEL J. SCOTT, SHARON LAYFIELD, GEOFFREY W. TREGEAR, ROSS A.D. BATHGATE, ANDREW L. GUNDLACH

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 1022 KB

english, 2005

70

Detection, Localization, and Action of the INSL3 Receptor, LGR8, in Rat Kidney

PING FU, PEI-JUAN SHEN, CHONG-XIN ZHAO, DANIEL J. SCOTT, CHRISHAN S. SAMUEL, JOHN D. WADE, GEOFFREY W. TREGEAR, ROSS A.D. BATHGATE, ANDREW L. GUNDLACH

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 3.71 MB

english, 2005

71

Searching the human genome database for novel relaxin- and insulin-like peptides

Ross A. D. Bathgate, Daniel J. Scott, Sean W. L. Chung, Daniel Ellyard, Amanda M. Garreffa, Geoffrey W. Tregear

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2001

Language:

english

File:

PDF, 67 KB

english, 2001

72

Mesotocin and Arginine-Vasopressin in the Corpus Luteum of an Australian Marsupial, the Brushtail Possum (Trichosurus vulpecula)

Conrad Sernia, Ross A.D. Bathgate, Robert T. Gemmell

Journal:

General and Comparative Endocrinology

Year:

1994

File:

PDF, 512 KB

1994

73

Mammalian Mesotocin: cDNA Sequence and Expression of an Oxytocin-like Gene in a Macropodid Marsupial, the Tammar Wallaby

Laura J. Parry, Ross A.D. Bathgate, Richard Ivell

Journal:

General and Comparative Endocrinology

Year:

2000

Language:

english

File:

PDF, 274 KB

english, 2000

74

Site-specific DOTA/europium-labeling of recombinant human relaxin-3 for receptor-ligand interaction studies

Zhang, Wei-Jie, Luo, Xiao, Liu, Ya-Li, Shao, Xiao-Xia, Wade, John D., Bathgate, Ross A. D., Guo, Zhan-Yun

Journal:

Year:

2012

Language:

english

File:

PDF, 407 KB

english, 2012

75

Relaxin family peptide receptors – from orphans to therapeutic targets

Emma T. van der Westhuizen, Michelle L. Halls, Chrishan S. Samuel, Ross A.D. Bathgate, Elaine N. Unemori, Steven W. Sutton, Roger J. Summers

Journal:

Drug Discovery Today

Year:

2008

Language:

english

File:

PDF, 1.77 MB

english, 2008

76

‘Relaxin’ the stiffened heart and arteries: The therapeutic potential for relaxin in the treatment of cardiovascular disease

Chrishan S. Samuel, Xiao-Jun Du, Ross A.D. Bathgate, Roger J. Summers

Journal:

Pharmacology & Therapeutics

Year:

2006

Language:

english

File:

PDF, 1.45 MB

english, 2006

77

Evolution of the relaxin-like peptide family

Tracey N Wilkinson, Terence P Speed, Geoffrey W Tregear, Ross AD Bathgate

Journal:

BMC Evolutionary Biology

Year:

2005

Language:

english

File:

PDF, 454 KB

english, 2005

78

Site-specific conjugation of a lanthanide chelator and its effects on the chemical synthesis and receptor binding affinity of human relaxin-2 hormone

Fazel Shabanpoor, Ross A.D. Bathgate, Alessia Belgi, Linda J. Chan, Vinojini B. Nair, John D. Wade, Mohammed Akhter Hossain

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 371 KB

english, 2012

79

Corrigendum to “Relaxin signaling in reproductive tissues” [Mol. Cell. Endocrinol. 202 (2003) 165–175]

Sheau Yu Teddy Hsu, Koji Nakabayashi, Shinya Nishi, Jin Kumagai, Masataka Kudo, Ross A.D. Bathgate, O. David Sherwood, Aaron J.W. Hsueh

Journal:

Molecular and Cellular Endocrinology

Year:

2005

Language:

english

File:

PDF, 29 KB

english, 2005

80

Negative cooperativity in H2 relaxin binding to a dimeric relaxin family peptide receptor 1

Angela Manegold Svendsen, Anna Zalesko, Julie Kønig, Milka Vrecl, Anders Heding, Jesper Bøggild Kristensen, John D. Wade, Ross A.D. Bathgate, Pierre De Meyts, Jane Nøhr

Journal:

Molecular and Cellular Endocrinology

Year:

2008

Language:

english

File:

PDF, 310 KB

english, 2008

81

Membrane receptors: Structure and function of the relaxin family peptide receptors

Roy C.K. Kong, Patrick J. Shilling, Derek K. Lobb, Paul R. Gooley, Ross A.D. Bathgate

Journal:

Molecular and Cellular Endocrinology

Year:

2010

Language:

english

File:

PDF, 951 KB

english, 2010

82

Swim stress excitation of nucleus incertus and rapid induction of relaxin-3 expression via CRF1 activation

Avantika Banerjee, Pei-Juan Shen, Sherie Ma, Ross A.D. Bathgate, Andrew L. Gundlach

Journal:

Neuropharmacology

Year:

2010

Language:

english

File:

PDF, 2.40 MB

english, 2010

83

A simple approach for the preparation of mature human relaxin-3

Xiao Luo, Ya-Li Liu, Sharon Layfield, Xiao-Xia Shao, Ross A.D. Bathgate, John D. Wade, Zhan-Yun Guo

Journal:

Year:

2010

Language:

english

File:

PDF, 437 KB

english, 2010

84

Chimeric relaxin peptides highlight the role of the A-chain in the function of H2 relaxin

Mohammed Akhter Hossain, John D. Wade, Ross A.D. Bathgate

Journal:

Year:

2012

Language:

english

File:

PDF, 350 KB

english, 2012

85

Neohormone systems as exciting targets for drug development

Richard Ivell, Ross Bathgate

Journal:

Trends in Endocrinology & Metabolism

Year:

2006

Language:

english

File:

PDF, 47 KB

english, 2006

86

Adenovirus-mediated delivery of relaxin reverses cardiac fibrosis in mice with fibrotic cardiomyopathy

Edna D. Lekgabe*, Yidan Su, Jonathan T. McGuane, Thao Pham, Sharon Layfield, Tania Ferraro, Ross Hannan, Walter Thomas, Chrishan S. Samuel, Xiao-Jun Du, Ross A.D. Bathgate

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2006

Language:

english

File:

PDF, 52 KB

english, 2006

87

Relaxin signaling in reproductive tissues

Sheau Yu Teddy Hsu, Koji Nakabayashi, Shinya Nishi, Jin Kumagai, Masataka Kudo, Ross A.D. Bathgate, O.David Sherwood, Aaron J.W. Hsueh

Journal:

Molecular and Cellular Endocrinology

Year:

2003

Language:

english

File:

PDF, 513 KB

english, 2003

88

Relaxin: new peptides, receptors and novel actions

Ross A.D. Bathgate, Chrishan S. Samuel, Tanya C.D. Burazin, Andrew L. Gundlach, Geoffrey W. Tregear

Journal:

Trends in Endocrinology & Metabolism

Year:

2003

Language:

english

File:

PDF, 1.37 MB

english, 2003

89

Solid phase synthesis and structural analysis of novel A-chain dicarba analogs of human relaxin-3 (INSL7) that exhibit full biological activity

Hossain, Mohammed Akhter, Rosengren, K. Johan, Zhang, Suode, Bathgate, Ross A. D., Tregear, Geoffrey W., van Lierop, Bianca J., Robinson, Andrea J., Wade, John D.

Journal:

Organic & Biomolecular Chemistry

Year:

2009

Language:

english

File:

PDF, 442 KB

english, 2009

90

Insulin 3: From chemical synthesis to biological function

Ping Fu, Ross A. D. Bathgate, Geoffrey W. Tregear, John D. Wade

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2003

Language:

english

File:

PDF, 145 KB

english, 2003

91

The relaxin peptide family and their novel G-protein coupled receptors

Daniel J. Scott, Tracey Wilkinson, Geoffrey W. Tregear, Ross A. D. Bathgate

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2003

Language:

english

File:

PDF, 219 KB

english, 2003

92

Design, Synthesis, and Characterization of a Single-Chain Peptide Antagonist for the Relaxin-3 Receptor RXFP3

Haugaard-Kedström, Linda M., Shabanpoor, Fazel, Hossain, Mohammed Akhter, Clark, Richard J., Ryan, Philip J., Craik, David J., Gundlach, Andrew L., Wade, John D., Bathgate, Ross A. D., Rosengren, K.

Journal:

Journal of the American Chemical Society

Year:

2011

Language:

english

File:

PDF, 2.81 MB

english, 2011

93

Preliminary Structure–Function Relationship Studies on Insulin-Like Peptide 5 (INSL5)

Alessia Belgi, Ross A. D. Bathgate…

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2013

Language:

english

File:

PDF, 362 KB

english, 2013

94

Relaxin 2000 ||

Tregear, Geoffrey W., Ivell, Richard, Bathgate, Ross A., Wade, John D.

Year:

2001

Language:

english

File:

PDF, 44.63 MB

english, 2001

95

Solid-Phase Synthesis of Europium-Labeled Human INSL3 as a Novel Probe for the Study of Ligand−Receptor Interactions

Shabanpoor, Fazel, Hughes, Richard A., Bathgate, Ross A. D., Zhang, Suode, Scanlon, Denis B., Lin, Feng, Hossain, Mohammed Akhter, Separovic, Frances, Wade, John D.

Journal:

Bioconjugate Chemistry

Year:

2008

Language:

english

File:

PDF, 370 KB

english, 2008

96

Relaxins enhance growth of spontaneous murine breast cancers as well as metastatic colonization of the brain

Binder, Claudia, Chuang, Eugenia, Habla, Christina, Bleckmann, Annalen, Schulz, Matthias, Bathgate, Ross, Einspanier, Almuth

Journal:

Clinical and Experimental Metastasis

Year:

2014

Language:

english

File:

PDF, 516 KB

english, 2014

97

Chemically prepared novel dicarba analogs of human relaxin-3, a recently discovered neuropeptide, exhibit full biological activity

Hossain, Mohammed Akhter, Rosengren, K.J., Bathgate, Ross A.D., van Lierop, Bianca J., Robinson, Andrea J., Wade, John D.

Journal:

Neuroscience Research

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010

98

Improving the apo-state detergent stability of NTS1 with CHESS for pharmacological and structural studies

Scott, Daniel J., Kummer, Lutz, Egloff, Pascal, Bathgate, Ross A.D., Plückthun, Andreas

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2014

Language:

english

File:

PDF, 1.69 MB

english, 2014

99

Minimum Active Structure of Insulin-like Peptide 5

Belgi, Alessia, Bathgate, Ross A. D., Kocan, Martina, Patil, Nitin, Zhang, Suode, Tregear, Geoffrey W., Wade, John D., Hossain, Mohammed Akhter

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 2.05 MB

english, 2013

100

Improved Chemical Synthesis and Demonstration of the Relaxin Receptor Binding Affinity and Biological Activity of Mouse Relaxin †

Samuel, Chrishan S., Lin, Feng, Hossain, Mohammed Akhter, Zhao, Chongxin, Ferraro, Tania, Bathgate, Ross A. D., Tregear, Geoffrey W., Wade, John D.

Journal:

Year:

2007

Language:

english

File:

PDF, 522 KB

english, 2007

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