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51

BIOANALYTICAL LIQUID CHROMATOGRAPHIC METHOD VALIDATION. A REVIEW OF CURRENT PRACTICES AND PROCEDURES

Rosing, H., Man, W. Y., Doyle, E., Bult, A., Beijnen, J. H.

Journal:

Journal of Liquid Chromatography & Related Technologies

Year:

2000

Language:

english

File:

PDF, 1.16 MB

english, 2000

52

Pharmacokinetic comparison of two methods of heroin smoking: ‘chasing the dragon’ versus the use of a heating device

Marjolein G. Klous, Alwin D.R. Huitema, Elisabeth J. Rook, Michel J.X. Hillebrand, Vincent M. Hendriks, Wim Van den Brink, Jos H. Beijnen, Jan M. Van Ree

Journal:

European Neuropsychopharmacology

Year:

2005

Language:

english

File:

PDF, 130 KB

english, 2005

53

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

A.H. Schinkel, J.J.M. Smit, O. van Tellingen, J.H. Beijnen, E. Wagenaar, L. van Deemter, C.A.A.M. Mol, M.A. van der Valk, E.C. Robanus-Maandag, H.P.J. te Riele, A.J.M. Berns, P. Borst

Journal:

Year:

1994

Language:

english

File:

PDF, 10.76 MB

english, 1994

54

PROGNOSTIC FACTORS FOR THE CLINICAL EFFECTIVENESS OF FLUCONAZOLE IN THE TREATMENT OF ORAL CANDIDIASIS IN HIV-1-INFECTED INDIVIDUALS

C.H.W KOKS, K.M.L CROMMENTUYN, R.A.A MATHÔT, J.W MULDER, P.L MEENHORST, J.H BEIJNEN

Journal:

Pharmacological Research

Year:

2002

Language:

english

File:

PDF, 79 KB

english, 2002

55

Multifilament Nb3Sn superconductors produced by the E.C.N. technique

van Beijnen, C., Elen, J.

Journal:

IEEE Transactions on Magnetics

Year:

1979

Language:

english

File:

PDF, 738 KB

english, 1979

56

Population Pharmacokinetics and Pharmacodynamics of Mitomycin During Intraoperative Hyperthermic Intraperitoneal Chemotherapy

Dr Serge van Ruth, Ron A. A. Mathôt, Rolf W. Sparidans, Jos H. Beijnen, Vic J. Verwaal, Frans A. N. Zoetmulder

Journal:

Clinical Pharmacokinetics

Year:

2004

Language:

english

File:

PDF, 206 KB

english, 2004

57

Individualised Cancer Chemotherapy: Strategies and Performance of Prospective Studies on Therapeutic Drug Monitoring with Dose Adaptation

Dr Milly E. de Jonge, Alwin D. R. Huitema, Jan H. M. Schellens, Sjoerd Rodenhuis, Jos H. Beijnen

Journal:

Clinical Pharmacokinetics

Year:

2005

Language:

english

File:

PDF, 205 KB

english, 2005

58

Population Pharmacokinetics of Efavirenz in an Unselected Cohort of HIV-1-Infected Individuals

Dr Bregt S. Kappelhoff, Alwin D. R. Huitema, Zeynep Yalvaç, Jan M. Prins, Jan W. Mulder, Pieter L. Meenhorst, Jos H. Beijnen

Journal:

Clinical Pharmacokinetics

Year:

2005

Language:

english

File:

PDF, 292 KB

english, 2005

59

Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

Ron J. Keizer, Alwin D. R. Huitema, Jan H. M. Schellens, Jos H. Beijnen

Journal:

Clinical Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 208 KB

english, 2010

60

Development and validation of an assay for the simultaneous determination of zidovudine, abacavir, emtricitabine, lamivudine, tenofovir and ribavirin in human plasma using liquid chromatography–tandem mass spectrometry

Kromdijk, W., Pereira, S.A., Rosing, H., Mulder, J.W., Beijnen, J.H., Huitema, A.D.R.

Journal:

Journal of Chromatography B

Year:

2013

Language:

english

File:

PDF, 750 KB

english, 2013

61

Effect of Chinese herbs on CYP3A4 activity and expression in vitro

Lau, C., Mooiman, K.D., Maas-Bakker, R.F., Beijnen, J.H., Schellens, J.H.M., Meijerman, I.

Journal:

Journal of Ethnopharmacology

Year:

2013

Language:

english

File:

PDF, 446 KB

english, 2013

62

A flexed posture in elderly patients is associated with impairments in postural control during walking

de Groot, Maartje H., van der Jagt-Willems, Hanna C., van Campen, Jos P.C.M., Lems, Willem F., Beijnen, Jos H., Lamoth, Claudine J.C.

Journal:

Year:

2014

Language:

english

File:

PDF, 497 KB

english, 2014

63

Multidrug Transporter ABCG2/Breast Cancer Resistance Protein Secretes Riboflavin (Vitamin B2) into Milk

van Herwaarden, A. E., Wagenaar, E., Merino, G., Jonker, J. W., Rosing, H., Beijnen, J. H., Schinkel, A. H.

Journal:

Molecular and Cellular Biology

Year:

2007

Language:

english

File:

PDF, 434 KB

english, 2007

64

A general approach to the interpretation of pH degradation profiles

van der Houwen, O.A.G.J., Beijnen, J.H., Bult, A., Underberg, W.J.M.

Journal:

International Journal of Pharmaceutics

Year:

1988

Language:

english

File:

PDF, 471 KB

english, 1988

65

Use of dried blood spots for the determination of serum concentrations of tamoxifen and endoxifen

Jager, N. G. L., Rosing, H., Schellens, J. H. M., Beijnen, J. H., Linn, S. C.

Journal:

Breast Cancer Research and Treatment

Year:

2014

Language:

english

File:

PDF, 673 KB

english, 2014

66

Characterization and identification of suspected counterfeit miltefosine capsules

Dorlo, Thomas P. C., Eggelte, Teunis A., de Vries, Peter J., Beijnen, Jos H.

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2012

Language:

english

File:

PDF, 1007 KB

english, 2012

67

Optimizing anticancer drug treatment in pregnant cancer patients: pharmacokinetic analysis of gestation-induced changes for doxorubicin, epirubicin, docetaxel and paclitaxel

van Hasselt, J. G. C., van Calsteren, K., Heyns, L., Han, S., Mhallem Gziri, M., Schellens, J. H. M., Beijnen, J. H., Huitema, A. D. R., Amant, F.

Journal:

Annals of Oncology

Year:

2014

Language:

english

File:

PDF, 223 KB

english, 2014

68

ADME-Enabling Technologies in Drug Design and Development . Edited by Donglu Zhang and Sekhar Surapaneni

Beijnen, Jos H.

Journal:

Year:

2013

Language:

english

File:

PDF, 120 KB

english, 2013

69

Manufacture of Gene-Modified Human T-Cells with a Memory Stem/Central Memory Phenotype

Gomez-Eerland, Raquel, Nuijen, Bastiaan, Heemskerk, Bianca, van Rooij, Nienke, van den Berg, Joost H., Beijnen, Jos H., Uckert, Wolfgang, Kvistborg, Pia, Schumacher, Ton N., Haanen, John B.A.G., Jorri

Journal:

Human Gene Therapy Methods

Year:

2014

Language:

english

File:

PDF, 690 KB

english, 2014

70

Cannulation of the jugular vein in mice: a method for serial withdrawal of blood samples

Bardelmeijer, H. A., Buckle, T., Ouwehand, M., Beijnen, J. H., Schellens, J. H. M., van Tellingen, O.

Journal:

Laboratory Animals

Year:

2003

Language:

english

File:

PDF, 184 KB

english, 2003

71

The Effect of Low pH on Breast Cancer Resistance Protein (ABCG2)-Mediated Transport of Methotrexate, 7-Hydroxymethotrexate, Methotrexate Diglutamate, Folic Acid, Mitoxantrone, Topotecan, and Resveratrol in In Vitro Drug Transport Models

Breedveld, P., Pluim, D., Cipriani, G., Dahlhaus, F., van Eijndhoven, M. A. J., de Wolf, C. J. F., Kuil, A., Beijnen, J. H., Scheffer, G. L., Jansen, G., Borst, P., Schellens, J. H. M.

Journal:

Molecular Pharmacology

Year:

2006

Language:

english

File:

PDF, 455 KB

english, 2006

72

Urinary excretion of paclitaxel and metabolites in a large series study

Panday, V. R N., Rosing, H., Huizing, M. T, Koopman, F. J, van Warmerdam, L. J., ten Bokkel Huinink, W. W, Beijnen, J. H

Journal:

Journal of Oncology Pharmacy Practice

Year:

1998

Language:

english

File:

PDF, 515 KB

english, 1998

73

Pharmacokinetics and Pharmacokinetic Variability of Heroin and its Metabolites: Review of the Literature

Rook, Elisabeth, Huitema, Alwin, Brink, Wim, Ree, Jan, Beijnen, Jos

Journal:

Current Clinical Pharmacology

Year:

2006

Language:

english

File:

PDF, 283 KB

english, 2006

74

Development and validation of a rapid and sensitive UPLC–MS/MS method for determination of uracil and dihydrouracil in human plasma

Jacobs, Bart A.W., Rosing, Hilde, de Vries, Niels, Meulendijks, Didier, Henricks, Linda M., Schellens, Jan H.M., Beijnen, Jos H.

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2016

Language:

english

File:

PDF, 886 KB

english, 2016

75

Determination of Ifosfamide, 2- and 3-Dechloroethyifosfamide Using Gas Chromatography With Nitrogen-Phosphorus or Mass Spectrometry Detection

Kerbusch, Thomas, Jeuken, Marie-Jos??, Derraz, Jamila, van Putten, John W. G., Huitema, Alwin D. R., Beijnen, Jos H.

Journal:

Therapeutic Drug Monitoring

Year:

2000

Language:

english

File:

PDF, 926 KB

english, 2000

76

Pharmaceutical development of anticancer agents derived from marine sources

Nuijen, B, Bouma, M, Manada, C, Jimeno, J M, Schellens, J HM, Bult, A, Beijnen, J H

Journal:

Anti-Cancer Drugs

Year:

2000

Language:

english

File:

PDF, 247 KB

english, 2000

77

Dried Blood Spot Self-Sampling at Home for the Individualization of Tamoxifen Treatment

Jager, Nynke G. L., Rosing, Hilde, Linn, Sabine C., Schellens, Jan H. M., Beijnen, Jos H.

Journal:

Therapeutic Drug Monitoring

Year:

2015

Language:

english

File:

PDF, 175 KB

english, 2015

78

Inventory of oral anticancer agents: pharmaceutical formulation aspects with focus on the solid dispersion technique

Sawicki, E., Schellens, J.H.M., Beijnen, J.H., Nuijen, B.

Journal:

Cancer Treatment Reviews

Year:

2016

Language:

english

File:

PDF, 1.00 MB

english, 2016

79

Thermal stability study of crystalline and novel spray-dried amorphous nilotinib hydrochloride

Herbrink, Maikel, Vromans, Herman, Schellens, Jan, Beijnen, Jos, Nuijen, Bastiaan

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2018

Language:

english

File:

PDF, 802 KB

english, 2018

80

Solubility and bioavailability improvement of pazopanib hydrochloride

Herbrink, Maikel, Groenland, Stefanie L., Huitema, Alwin D.R., Schellens, Jan H.M., Beijnen, Jos H., Steeghs, Neeltje, Nuijen, Bastiaan

Journal:

International Journal of Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.00 MB

english, 2018

81

Review of Chromatographic Bioanalytical Assays for the Quantitative Determination of Marine-Derived Drugs for Cancer Treatment

van Andel, Lotte, Rosing, Hilde, Schellens, Jan, Beijnen, Jos

Journal:

Year:

2018

Language:

english

File:

PDF, 2.27 MB

english, 2018

82

Therapeutic Drug Monitoring of endoxifen as an alternative for CYP2D6 genotyping in individualizing tamoxifen therapy

de Vries Schultink, Aurelia H.M., Huitema, Alwin D.R., Beijnen, Jos H.

Journal:

Year:

2018

Language:

english

File:

PDF, 216 KB

english, 2018

83

Predictive Value of Microdose Pharmacokinetics

van Nuland, Merel, Rosing, Hilde, Huitema, Alwin D. R., Beijnen, Jos H.

Journal:

Clinical Pharmacokinetics

Year:

2019

Language:

english

File:

PDF, 995 KB

english, 2019

84

Relevance of Endoxifen Concentrations: Absence of Evidence Is Not Evidence of Absence

Braal, C. Louwrens, Beijnen, Jos H., Koolen, Stijn L.W., Oomen-de Hoop, Esther, Steeghs, Neeltje, Jager, Agnes, Huitema, Alwin D.R., Mathijssen, Ron H.J.

Journal:

Journal of Clinical Oncology

Year:

2019

Language:

english

File:

PDF, 458 KB

english, 2019

85

Development and validation of a liquid chromatography-tandem mass spectrometry assay for nine oral anticancer drugs in human plasma

Janssen, Julie M., de Vries, Niels, Venekamp, Nikkie, Rosing, Hilde, Huitema, Alwin D.R., Beijnen, Jos H.

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2019

Language:

english

File:

PDF, 540 KB

english, 2019

86

Exposure–response analyses of abiraterone and its metabolites in real-world patients with metastatic castration-resistant prostate cancer

van Nuland, M., Groenland, S. L., Bergman, A. M., Steeghs, N., Rosing, H., Venekamp, N., Huitema, A. D. R., Beijnen, J. H.

Journal:

Prostate Cancer and Prostatic Diseases

Year:

2019

Language:

english

File:

PDF, 611 KB

english, 2019

87

Bottom-up sample preparation for the LCâMS/MS quantification of anti-cancer monoclonal antibodies in bio matrices

de Jong, Karen AM, van Breugel, Suse J, Hillebrand, Michel JX, Rosing, Hilde, Huitema, Alwin DR, Beijnen, Jos H

Journal:

Year:

2020

File:

PDF, 789 KB

2020

88

Quantitative determination of Ecteinascidin 743 in human plasma by miniaturized high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry

Rosing, H., Hillebrand, M. J. X., Jimeno, J. M., Gómez, A., Floriano, P., Faircloth, G., Henrar, R. E. C., Vermorken, J. B., Cvitkovic, E., Bult, A., Beijnen, J. H.

Journal:

Journal of Mass Spectrometry

Year:

1998

Language:

english

File:

PDF, 124 KB

english, 1998

89

Degradation of azaglycinamido residues in model tripeptides derived from goserelin

Marnix A. Hoitink, Jos H. Beijnen, Auke Bult, J. Mirjam A. Damen, Oeds A. G. J. van der Houwen, John A. W. Kruijtzer, Matthijs M. Tibben, Gerard Wiese, Willy J. M. Underberg

Journal:

Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 198 KB

english, 2000

90

Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis

Pilar Barrera, Arjen Blom, Peter L. E. M. Van Lent, Louis Van Bloois, Jos H. Beijnen, Nico Van Rooijen, Maarten C. De Waal Malefijt, Leo B. A. Van De Putte, Gert Storm, Wim B. Van Den Berg

Journal:

Arthritis & Rheumatism

Year:

2000

Language:

english

File:

PDF, 802 KB

english, 2000

91

Distribution of ifosfamide and metabolites between plasma and erythrocytes

T. Kerbusch, V.M.M. Herben, M-J.J. Jeuken, J. Ouwerkerk, H.J. Keizer, J.H. Beijnen

Journal:

Biopharmaceutics & Drug Disposition

Year:

2001

Language:

english

File:

PDF, 119 KB

english, 2001

92

The bioanalysis of vinorelbine and 4-O-deacetylvinorelbine in human and mouse plasma using high-performance liquid chromatography coupled with heated electrospray ionization tandem mass–spectrometry

Carola W. N. Damen, Jurjen S. Lagas, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen

Journal:

Biomedical Chromatography

Year:

2009

Language:

english

File:

PDF, 451 KB

english, 2009

93

High-performance liquid chromatography coupled with mass spectrometry for the quantitative analysis of vinca-alkaloids in biological matrices: a concise survey from the literature

Carola W. N. Damen, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen

Journal:

Biomedical Chromatography

Year:

2010

Language:

english

File:

PDF, 402 KB

english, 2010

94

A new, validated HPLC-MS/MS method for the simultaneous determination of the anti-cancer agent capecitabine and its metabolites: 5′-deoxy-5-fluorocytidine, 5′-deoxy-5-fluorouridine, 5-fluorouracil and 5-fluorodihydrouracil, in human plasma

Liia D. Vainchtein, Hilde Rosing, Jan H.M. Schellens, Jos H. Beijnen

Journal:

Biomedical Chromatography

Year:

2010

Language:

english

File:

PDF, 556 KB

english, 2010

95

Simple high-performance liquid chromatographic assay for melphalan in perfusate, rat liver and tumour tissue

Rolf W. Sparidans, Linda Silvertand, Frits Dost, Joost Rothbarth, Gerard J. Mulder, Jan H. M. Schellens, Jos H. Beijnen

Journal:

Biomedical Chromatography

Year:

2003

Language:

english

File:

PDF, 132 KB

english, 2003

96

Liquid chromatographic assay for the cyclic depsipeptide aplidine, a new marine antitumor drug, in whole blood using derivatization with trans-4′-hydrazino-2-stilbazole

Rolf W. Sparidans, Jan H. M. Schellens, Luis López-Lázaro, José M. Jimeno, Jos H. Beijnen

Journal:

Biomedical Chromatography

Year:

2004

Language:

english

File:

PDF, 86 KB

english, 2004

97

Switching from an analogous to a stable isotopically labeled internal standard for the LC-MS/MS quantitation of the novel anticancer drug Kahalalide F signiﬁcantly improves assay performance

E. Stokvis, H. Rosing, L. López-Lázaro, J. H. M. Schellens, J. H. Beijnen

Journal:

Biomedical Chromatography

Year:

2004

Language:

english

File:

PDF, 163 KB

english, 2004

98

A more sensitive MS detector does not obviously lead to a more sensitive assay: experiences with ES-285

Ellen Stokvis, Hilde Rosing, Luis López-Lázaro, Jan H. M. Schellens, Jos H. Beijnen

Journal:

Biomedical Chromatography

Year:

2004

Language:

english

File:

PDF, 129 KB

english, 2004

99

Quantitative analysis of docetaxel in human plasma using liquid chromatography coupled with tandem mass spectrometry

I. E. L. M. Kuppens, M. J. van Maanen, H. Rosing, J. H. M. Schellens, J. H. Beijnen

Journal:

Biomedical Chromatography

Year:

2005

Language:

english

File:

PDF, 189 KB

english, 2005

100

Liquid chromatographic assay for the protease inhibitor atazanavir in plasma

Rolf W. Sparidans, Frits Dost, Kristel M. L. Crommentuyn, Alwin D. R. Huitema, Jan H. M. Schellens, Jos H. Beijnen

Journal:

Biomedical Chromatography

Year:

2006

Language:

english

File:

PDF, 107 KB

english, 2006