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1

The osmium-catalyzed asymmetric dihydroxylation: a new ligand class and a process improvement

Sharpless, K. Barry, Amberg, Willi, Bennani, Youssef L., Crispino, Gerard A., Hartung, Jens, Jeong, Kyu Sung, Kwong, Hoi Lun, Morikawa, Kouhei, Wang, Zhi Min

Journal:

Journal of Organic Chemistry

Year:

1992

Language:

english

File:

PDF, 1.00 MB

english, 1992

2

Natural Products in Medicine: Transformational Outcome of Synthetic Chemistry

Szychowski, Janek, Truchon, Jean-François, Bennani, Youssef L.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.50 MB

english, 2014

3

4-(2-[2-(2( R )-Methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and Related 2-Aminoethylbenzofuran H 3 Receptor Antagonists Potently Enhance Cognition and Attention

Cowart, Marlon, Faghih, Ramin, Curtis, Michael P., Gfesser, Gregory A., Bennani, Youssef L., Black, Lawrence A., Pan, Liping, Marsh, Kennan C., Sullivan, James P., Esbenshade, Timothy A., Fox, Gerard

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 371 KB

english, 2005

4

Structural basis of noscapine activation for tubulin binding

Oliva, Maria A, Prota, Andrea E., RodrÃguez-Salarichs, Javier, Gu, Wenxin, Bennani, Youssef L., JimÃ©nez-Barbero, JesÃºs, Bargsten, Katja, Canales, Angeles, Steinmetz, Michel O., DÃaz, J. Fernando

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 3.29 MB

2020

5

D-Amino Acid Homopiperazine Amides: Discovery of A-320436, a Potent and Selective Non-Imidazole Histamine H3-Receptor Antagonist

Michael P. Curtis, Wesley Dwight, John Pratt, Marlon Cowart, Timothy A. Esbenshade, Kathy M. Krueger, Gerard B. Fox, Jia Bao Pan, Thomas G. Pagano, Arthur A. Hancock, Ramin Faghih, Youssef L. Bennani

Journal:

Archiv der Pharmazie

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

6

ChemInform Abstract: Synthesis of 8(R),9(R)-9-Deoxo-4′′-deoxy-6,9-epoxyerythromycin: Potent Motilides.

Ramin Faghih, Cynthia Burnell-Curty, Paul A. Lartey, Albert Petersen, Larry L. Klein, Youssef L. Bennani, Hugh N. Nellans

Journal:

Year:

1999

File:

PDF, 33 KB

1999

7

Aminoalkoxybiphenylnitriles as Histamine-3 Receptor Ligands.

Ramin Faghih, Wesley Dwight, Anil Vasudevan, Jurgen Dinges, Scott E. Conner, Timothy A. Esbenshade, Youssef L. Bennani, Arthur A. Hancock

Journal:

Year:

2003

File:

PDF, 61 KB

2003

8

A New Class of Histamine H3-Receptor Antagonists: Synthesis and Structure—Activity Relationships of 7,8,9,10-Tetrahydro-6H-cyclohepta[b]quinolines

Sean C. Turner, Timothy A. Esbenshade, Youssef L. Bennani, Arthur A. Hancock

Journal:

Year:

2003

File:

PDF, 135 KB

2003

9

A New Class of Potent Non-imidazole H3 Antagonists: 2-Aminoethylbenzofurans.

Marlon Cowart, John K. Pratt, Andrew O. Stewart, Youssef L. Bennani, Timothy A. Esbenshade, Arthur A. Hancock

Journal:

Year:

2004

File:

PDF, 109 KB

2004

10

ChemInform Abstract: A Novel Chemotype of Kinase Inhibitors: Discovery of 3,4-Ring Fused 7-Azaindoles and Deazapurines as Potent JAK2 Inhibitors.

Tiansheng Wang, Mark W. Ledeboer, John P. Duffy, Albert C. Pierce, Harmon J. Zuccola, Eric Block, Dina Shlyakter, James K. Hogan, Youssef L. Bennani

Journal:

Year:

2010

File:

PDF, 30 KB

2010

11

Synthesis of 1-[13CD3]-9-cis-retinoic acid

Youssef L. Bennani

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1995

Language:

english

File:

PDF, 430 KB

english, 1995

12

The asymmetric synthesis of α-substituted α-methyl and α-phenyl phosphonic acids: Design, carbanion geometry, reactivity and preparative aspects of chiral alkyl bicyclic phosphonamides

Youssef L. Bennani, Stephen Hanessian

Journal:

Year:

1996

Language:

english

File:

PDF, 1.84 MB

english, 1996

13

Synthesis of geometrically defined exocyclic olefins

Youssef L. Bennani, C.-K. Hwang, Stacie S. Canan Koch, Kristin S. Marron, Laura J. Dar-ti, Beth-Ann Badea, Alex M. Nadzan

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 221 KB

english, 1996

14

A short route to a moshe'rs acid precursor via catalytic asymmetric dihydroxylation (AD)

Youssef L. Bennani, Koen P.M. Vanhessche, K.Barry Sharpless

Journal:

Tetrahedron: Asymmetry

Year:

1994

Language:

english

File:

PDF, 267 KB

english, 1994

15

A new class of potent non-imidazole H3 antagonists: 2-aminoethylbenzofurans

Marlon Cowart, John K. Pratt, Andrew O. Stewart, Youssef L. Bennani, Timothy A. Esbenshade, Arthur A. Hancock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 242 KB

english, 2004

16

Structure–activity relationships of non-imidazole H3 receptor ligands. Part 3: 5-Substituted 3-phenyl-1,2,4-oxadiazoles as potent antagonists

Gregory A. Gfesser, Henry Zhang, Jurgen Dinges, Gerard B. Fox, Jia Bao Pan, Timothy A. Esbenshade, Betty B. Yao, David Witte, Thomas R. Miller, Chae-Hee Kang, Kathy M. Krueger, Youssef L. Bennani, Art

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 235 KB

english, 2004

17

The design and synthesis of a tricyclic single-nitrogen scaffold that serves as a 5-HT2C receptor agonist

Bayard R. Huck, Luis Llamas, Michael J. Robarge, Thomas C. Dent, Jianping Song, William F. Hodnick, Chris Crumrine, Alain Stricker-Krongrad, John Harrington, Kurt R. Brunden, Youssef L. Bennani

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 136 KB

english, 2006

18

A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors

Tiansheng Wang, Mark W. Ledeboer, John P. Duffy, Albert C. Pierce, Harmon J. Zuccola, Eric Block, Dina Shlyakter, James K. Hogan, Youssef L. Bennani

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 560 KB

english, 2010

19

Corrigendum to “A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors” [Bioorg. Med. Chem. Lett. 20 (2010) 153]

Tiansheng Wang, Mark W. Ledeboer, John P. Duffy, Francesco G. Salituro, Albert C. Pierce, Harmon J. Zuccola, Eric Block, Dina Shlyakter, James K. Hogan, Youssef L. Bennani

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 104 KB

english, 2010

20

Investigation of 4-piperidinols as novel H3 antagonists

James T. Anderson, Michael Campbell, Jianmin Wang, Kurt R. Brunden, John J. Harrington, Alain Stricker-Krongrad, Jianping Song, Chris Doucette, Steven Murphy, Youssef L. Bennani

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 425 KB

english, 2010

21

Modified cinchona alkaloid ligands: Improved selectivities in the osmium tetroxide catalyzed asymmetric dihydroxylation (AD) of terminal olefins

Mark P. Arrington, Youssef L. Bennani, Thomas Göbel, Patrick Walsh, Shu-Hai Zhao, K.Barry Sharpless

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 223 KB

english, 1993

22

Asymmetric Synthesis of γ-Hydroxy α,β-Unsaturated Amides via an AD-elimination Process; Synthesis of (+)-Coriolic Acid

Youssef L Bennani, K.Barry Sharpless

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 265 KB

english, 1993

23

Asymmetric dihydroxylation (AD) of N,N-dialkyl and N-methoxy-N-methyl α,β- and β,γ-unsaturated amides

Youssef L. Bennani, K.Barry Sharpless

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 254 KB

english, 1993

24

Asymmetric dihydroxylation (AD)/cyclization of N-diBoc allylic and homoallylic amines: Selective differentiation of the hydroxyl groups.

Patrick J. Walsh, Youssef L. Bennani, K.Barry Sharpless

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 243 KB

english, 1993

25

A versatile asymmetric synthesis of α-amino α-alkyl-phosphonic acids of high enantiomeric purity

Stephen Hanessian, Youssef L. Bennani

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 312 KB

english, 1990

26

The asymmetric synthesis of α-chloro α-alkyl and α-methyl α-alkyl phosphonic acids of high enantiomeric purity.

Stephen Hanessian, Youssef L. Bennani, Daniel Delorme

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 272 KB

english, 1990

27

Short and practical syntheses of(R)-(−)-carnitine and (R)-(−)-γ-amino-β-hydroxybutyric acid (GABOB)

Hartmuth C. Kolb, Youssef L. Bennani, K.Barry Sharpless

Journal:

Tetrahedron: Asymmetry

Year:

1993

Language:

english

File:

PDF, 649 KB

english, 1993

28

Synthesis and evaluation of potent pyrrolidine H3 antagonists

Anil Vasudevan, Scott E. Conner, Robert G. Gentles, Ramin Faghih, Huaqing Liu, Wesley Dwight, Lynne Ireland, Chae Hee Kang, Timothy A. Esbenshade, Youssef L. Bennani, Arthur A. Hancock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 115 KB

english, 2002

29

In vivo characterization of A-192411: a novel fungicidal lipopeptide (II)

Jonathan A Meulbroek, Angela M Nilius, Qun Li, Weibo Wang, Lisa Hasvold, Beth Steiner, Daniel A Dickman, Hong Ding, David Frost, Robert C Goldman, Paul Lartey, Jacob J Plattner, Youssef L Bennani

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 115 KB

english, 2003

30

Synthesis and SAR of aminoalkoxy-biaryl-4-carboxamides: novel and selective histamine H3 receptor antagonists

Ramin Faghih, Wesley Dwight, Jia Bao Pan, Gerard B. Fox, Kathy M. Krueger, Timothy A. Esbenshade, Jill M. McVey, Kennan Marsh, Youssef L. Bennani, Arthur A. Hancock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 173 KB

english, 2003

31

A new class of histamine H3-Receptor antagonists: synthesis and structure–Activity relationships of 7,8,9,10-Tetrahydro-6H-cyclohepta[b]quinolines

Sean C. Turner, Timothy A. Esbenshade, Youssef L. Bennani, Arthur A. Hancock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 179 KB

english, 2003

32

Preparation of 9-deoxo-4″-deoxy-6,9-epoxyerythromycin lactams “motilactides”: Potent and orally active prokinetic agents

Ramin Faghih, Hugh N. Nellans, Paul A. Lartey, Albert Petersen, Kennan Marsh, Youssef L. Bennani, Jacob J. Plattner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 271 KB

english, 1998

33

Structure–activity relationships of arylbenzofuran H3 receptor antagonists

Gregory A. Gfesser, Ramin Faghih, Youssef L. Bennani, Michael P. Curtis, Timothy A. Esbenshade, Arthur A. Hancock, Marlon D. Cowart

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 147 KB

english, 2005

34

Aza-retinoids as novel retinoid X receptor-specific agonists

Luc J. Farmer, Kristen S. Marron, Stacie S. Canan Koch, C.K. Hwang, E Adam Kallel, Lin Zhi, Alex M. Nadzan, Dave W. Robertson, Youssef L. Bennani

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 158 KB

english, 2006

35

The identification of pyrimidine-diazabicyclo[3.3.0]octane derivatives as 5-HT2C receptor agonists

Bayard R. Huck, Luis Llamas, Michael J. Robarge, Thomas C. Dent, Jianping Song, William F. Hodnick, Chris Crumrine, Alain Stricker-Krongrad, John Harrington, Kurt R. Brunden, Youssef L. Bennani

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 147 KB

english, 2006

36

4-[6-(2-Aminoethyl)naphthalen-2-yl]benzonitriles are potent histamine H3 receptor antagonists with high CNS penetration

Lawrence A. Black, Diana L. Nersesian, Padam Sharma, Yi-Yin Ku, Youssef L. Bennani, Kennan C. Marsh, Thomas R. Miller, Timothy A. Esbenshade, Arthur A. Hancock, Marlon Cowart

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 144 KB

english, 2007

37

Synthesis of 8(R),9(R)-9-deoxo-4''-deoxy-6,9-epoxyerythromycin: potent motilides

Ramin Faghih, Cynthia Burnell-Curty, Paul A. Lartey, Albert Petersen, Larry L. Klein, Youssef L. Bennani, Hugh N. Nellans

Journal:

European Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 88 KB

english, 1999

38

Aminoalkoxybiphenylnitriles as histamine-3 receptor ligands

Ramin Faghih, Wesley Dwight, Anil Vasudevan, Jurgen Dinges, Scott E. Conner, Timothy A. Esbenshade, Youssef L. Bennani, Arthur A. Hancock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 90 KB

english, 2002

39

Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonist

Timothy A Esbenshade, Gerard B Fox, Kathleen M Krueger, John L Baranowski, Thomas R Miller, Chae Hee Kang, Lynne I Denny, David G Witte, Betty B Yao, Jia Bao Pan, Ramin Faghih, Youssef L Bennani, Mich

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 307 KB

english, 2004

40

Drug discovery in the next decade: innovation needed ASAP

Youssef L. Bennani

Journal:

Drug Discovery Today

Year:

2011

Language:

english

File:

PDF, 1001 KB

english, 2011

41

Drug discovery in the next decade: innovation needed ASAP

Youssef L. Bennani

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 870 KB

english, 2012

42

Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist

Arthur A. Hancock, Youssef L. Bennani, Eugene N. Bush, Timothy A. Esbenshade, Ramin Faghih, Gerard B. Fox, Peer Jacobson, Victoria Knourek-Segel, Kathleen M. Krueger, Merrill E. Nuss, Jia Bao Pan, Rob

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 846 KB

english, 2004

43

Differential in vivo effects of H3 receptor ligands in a new mouse dipsogenia model

Gerard B. Fox, Jia Bao Pan, Timothy A. Esbenshade, R.Scott Bitner, Arthur L. Nikkel, Tom Miller, Chae Hee Kang, Youssef L. Bennani, Lawrence A. Black, Ramin Faghih, Arthur A. Hancock, Michael W. Decke

Journal:

Pharmacology Biochemistry and Behavior

Year:

2002

Language:

english

File:

PDF, 604 KB

english, 2002

44

A rare case of locally advanced fibrosarcoma of diaphysal humerus managed successfully with limb-sparing procedures after neoadjuvant chemotherapy

Omar El Mesbahi, Samia Arifi, Zineb Benbrahim, Abdelhalim El Ibrahimi, Fouad Kettani, Amal Bennani, Afaf Amarti, My Youssef Alaoui Lamrani, Siham Tizniti, Abdelmajid El Mrini

Journal:

World Journal of Surgical Oncology

Year:

2010

Language:

english

File:

PDF, 911 KB

english, 2010

45

Evidence for tolerance following repeated dosing in rats with ciproxifan, but not with A-304121

Jia Bao Pan, Betty B. Yao, Thomas R. Miller, Paul E. Kroeger, Youssef L. Bennani, Victoria A. Komater, Timothy A. Esbenshade, Arthur A. Hancock, Michael W. Decker, Gerard B. Fox

Journal:

Year:

2006

Language:

english

File:

PDF, 349 KB

english, 2006

46

Effects of histamine H3 receptor ligands GT-2331 and ciproxifan in a repeated acquisition avoidance response in the spontaneously hypertensive rat pup

Gerard B Fox, Jia Bao Pan, Timothy A Esbenshade, Youssef L Bennani, Lawrence A Black, Ramin Faghih, Arthur A Hancock, Michael W Decker

Journal:

Behavioural Brain Research

Year:

2002

Language:

english

File:

PDF, 468 KB

english, 2002

47

Tubulin Binding, Protein-Bound Conformation in Solution, and Antimitotic Cellular Profiling of Noscapine and Its Derivatives

Bennani, Youssef L., Gu, Wenxin, Canales, Angeles, Dı́az, Fernando J., Eustace, Brenda K., Hoover, Russell R., Jiménez-Barbero, Jesus, Nezami, Azin, Wang, Tiansheng

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 262 KB

english, 2012

48

The Alkaloid Conessine and Analogues as Potent Histamine H 3 Receptor Antagonists

Zhao, Chen, Sun, Minghua, Bennani, Youssef L., Gopalakrishnan, Sujatha M., Witte, David G., Miller, Thomas R., Krueger, Kathleen M., Browman, Kaitlin E., Thiffault, Christine, Wetter, Jill, Marsh, Ken

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 152 KB

english, 2008

49

Asymmetric dihydroxylation of olefins with a simple chiral ligand

Hanessian, Stephen, Meffre, Patrick, Girard, Mario, Beaudoin, Serge, Sanceau, Jean Yves, Bennani, Youssef

Journal:

Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 293 KB

english, 1993

50

trans -1,2-Diaminocyclohexane Derivatives as Chiral Reagents, Scaffolds, and Ligands for Catalysis: Applications in Asymmetric Synthesis and Molecular Recognition

Bennani, Youssef L., Hanessian, Stephen

Journal:

Chemical Reviews

Year:

1997

Language:

english

File:

PDF, 3.10 MB

english, 1997