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1

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

Uyttenhove, Catherine, Pilotte, Luc, Théate, Ivan, Stroobant, Vincent, Colau, Didier, Parmentier, Nicolas, Boon, Thierry, Van den Eynde, Benoît J

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 1.24 MB

english, 2003

2

Tumor Antigens Recognized by T Lymphocytes

Boon, Thierry, Cerottini, Jean-Charles, Van den Eynde, Benoit, van der Bruggen, Pierre, Van Pel, Aline

Journal:

Annual Review of Immunology

Year:

1994

Language:

english

File:

PDF, 764 KB

english, 1994

3

Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy

Coulie, Pierre G., Van den Eynde, Benoît J., van der Bruggen, Pierre, Boon, Thierry

Journal:

Nature Reviews Cancer

Year:

2014

Language:

english

File:

PDF, 1.02 MB

english, 2014

4

Renal-cell carcinoma-specific lysis by cytotoxic T-lymphocyte clones isolated from peripheral blood lymphocytes and tumor-infiltrating lymphocytes

Nathalie Brouwenstijn, Béatrice Gaugler, K. Margaretha Krüse, Corry W. van der Spek, Arend Mulder, Susanne Osanto, Benoît J. van den Eynde, Peter I. Schrier

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 604 KB

english, 1996

5

The expression of mouse gene P1A in testis does not prevent safe induction of cytolytic T cells against a P1A-encoded tumor antigen

Catherine Uyttenhove, Catherine Godfraind, Bernard Lethé, Alain Amar-Costesec, Jean-Christophe Renauld, Thomas F. Gajewski, Marie-Thérèse Duffour, Guy Warnier, Thierry Boon, Benoît J. Van den Eynde

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 288 KB

english, 1997

6

A tyrosinase peptide presented by HLA-B35 is recognized on a human melanoma by autologous cytotoxic T lymphocytes

Sandra Morel, Annie Ooms, Aline Van Pel, Thomas Wölfel, Vincent G. Brichard, Pierre Van der Bruggen, Benoît J. Van den Eynde, Gérard Degiovanni

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 121 KB

english, 1999

7

The shared tumor-specific antigen encoded by mouse gene P1A is a target not only for cytolytic T lymphocytes but also for tumor rejection

Daniel Brändle, Janine Bilsborough, Thomas Rülicke, Catherine Uyttenhove, Thierry Boon, Benoît J. Van den Eynde

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 150 KB

english, 1998

8

Mouse tumor rejection antigens P815A and P815B : Two epitopes carried by a single peptide

Bernard Lethé, Benoǐt Van den Eynde, Aline Van Pel, Giampietro Corradin, Thierry Boon

Journal:

European Journal of Immunology

Year:

1992

Language:

english

File:

PDF, 776 KB

english, 1992

9

Localization of two cytotoxic T lymphocyte epitopes and three anchoring residues on a single nonameric peptide that binds to H-2Ld and is recognized by cytotoxic T lymphocytes against mouse tumor P815

Benoǐt Van den Eynde, Honoré Mazarguil, Bernard Lethé, Françoise Laval, Jean Edouard Gairin

Journal:

European Journal of Immunology

Year:

1994

Language:

english

File:

PDF, 652 KB

english, 1994

10

Differences in the production of spliced antigenic peptides by the standard proteasome and the immunoproteasome

Alexandre Dalet, Vincent Stroobant, Nathalie Vigneron, Benoît J. Van den Eynde

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 869 KB

english, 2011

11

Two new tumor-specific antigenic peptides encoded by gene MAGE-C2 and presented to cytolytic T lymphocytes by HLA-A2

Wenbin Ma, Catherine Germeau, Nathalie Vigneron, Anne-Sophie Maernoudt, Sandra Morel, Thierry Boon, Pierre G. Coulie, Benoît J. Van den Eynde

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 236 KB

english, 2004

12

A MAGE-C2 antigenic peptide processed by the immunoproteasome is recognized by cytolytic T cells isolated from a melanoma patient after successful immunotherapy

Wenbin Ma, Nathalie Vigneron, Jacques Chapiro, Vincent Stroobant, Catherine Germeau, Thierry Boon, Pierre G. Coulie, Benoît J. Van den Eynde

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 560 KB

english, 2011

13

High expression of indoleamine 2,3-dioxygenase in the tumour is associated with medullary features and favourable outcome in basal-like breast carcinoma

Jocelyne Jacquemier, François Bertucci, Pascal Finetti, Benjamin Esterni, Emmanuelle Charafe-Jauffret, Marie-Laure Thibult, Gilles Houvenaeghel, Benoit Van den Eynde, Daniel Birnbaum, Daniel Olive, Lu

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 500 KB

english, 2012

14

Molecular definition of tumor antigens recognized by T lymphocytes

Pierre van der Bruggen, Benoit Van den Eynde

Journal:

Current Opinion in Immunology

Year:

1992

Language:

english

File:

PDF, 726 KB

english, 1992

15

New tumor antigens recognized by T cells

Benoît Van den Eynde, Vincent G Brichard

Journal:

Current Opinion in Immunology

Year:

1995

Language:

english

File:

PDF, 845 KB

english, 1995

16

Processing and presentation of tumor antigens and vaccination strategies

Pierre van der Bruggen, Benoît J Van den Eynde

Journal:

Current Opinion in Immunology

Year:

2006

Language:

english

File:

PDF, 208 KB

english, 2006

17

Tumor antigens recognized by T cells

Thierry Boon, Pierre G. Coulie, Benoît Van den Eynde

Journal:

Immunology Today

Year:

1997

Language:

english

File:

PDF, 402 KB

english, 1997

18

Tumour immunology

Thierry Boon, Benoit Van den Eynde

Journal:

Current Opinion in Immunology

Year:

2003

Language:

english

File:

PDF, 50 KB

english, 2003

19

T cell defined tumor antigens

Benoît J Van den Eynde, Pierre van der Bruggen

Journal:

Current Opinion in Immunology

Year:

1997

Language:

english

File:

PDF, 1.05 MB

english, 1997

20

Tumor-specific shared antigenic peptides recognized by human T cells

Pierre Van Der Bruggen, Yi Zhang, Pascal Chaux, Vincent Stroobant, Christophe Panichelli, Erwin S. Schultz, Jacques Chapiro, Benoît J. Van den Eynde, Francis Brasseur, Thierry Boon

Journal:

Immunological Reviews

Year:

2002

Language:

english

File:

PDF, 192 KB

english, 2002

21

A new gene coding for an antigen recognized by autologous cytolytic T lymphocytes on a human renal carcinoma

Béatrice Gaugler, Nathalie Brouwenstijn, Valérie Vantomme, Jean-Pierre Szikora, Corry W. Van der Spek, Jean-Jacques Patard, Thierry Boon, Peter Schrier, Benoît J. Van den Eynde

Journal:

Year:

1996

Language:

english

File:

PDF, 284 KB

english, 1996

22

Insights into the processing of MHC class I ligands gained from the study of human tumor epitopes

Nathalie Vigneron, Benoît J. Van den Eynde

Journal:

Cellular and Molecular Life Sciences

Year:

2011

Language:

english

File:

PDF, 497 KB

english, 2011

23

Genotypic and Gene Expression Studies in Congenital Melanocytic Nevi: Insight into Initial Steps of Melanotumorigenesis

De Raeve, Linda E, Morandini, Renato, Lefort, Anne, El Housni, Hakim, Dessars, Barbara, Ghanem, Ghanem E, Van den Eynde, Benoît J, Ma, Wenbin, Roseeuw, Diane, Vassart, Gilbert

Journal:

The Journal of Investigative Dermatology

Year:

2008

Language:

english

File:

PDF, 1.09 MB

english, 2008

24

Production of an antigenic peptide by insulin-degrading enzyme

Parmentier, Nicolas, Stroobant, Vincent, Colau, Didier, de Diesbach, Philippe, Morel, Sandra, Chapiro, Jacques, van Endert, Peter, Van den Eynde, Benoît J

Journal:

Nature Immunology

Year:

2010

Language:

english

File:

PDF, 456 KB

english, 2010

25

Inefficient exogenous loading of a tapasin-dependent peptide onto HLA-B*44:02 can be improved by acid treatment or fixation of target cells

Vincent Stroobant, Nathalie Demotte, Rosalie M. Luiten, Ralf M. Leonhardt, Peter Cresswell, Aude Bonehill, Alexandre Michaux, Wenbin Ma, Arend Mulder, Benoît J. Van den Eynde, Pierre van der Bruggen,

Journal:

European Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 907 KB

english, 2012

26

Rational Design of 4-Aryl-1,2,3-Triazoles for Indoleamine 2,3-Dioxygenase 1 Inhibition

Röhrig, Ute F., Majjigapu, Somi Reddy, Grosdidier, Aurélien, Bron, Sylvian, Stroobant, Vincent, Pilotte, Luc, Colau, Didier, Vogel, Pierre, Van den Eynde, Benoît J., Zoete, Vincent, Michielin, Olivier

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 3.82 MB

english, 2012

27

Antigens recognized on human tumors by cytolytic T lymphocytes

Pierre Coulie, Pierre van der Bruggen, Benoit Van Den Eynde, Vincent Brichard, Aline Van Pel, Etienne De Plaen, Thierry Boon

Journal:

European Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 127 KB

english, 1995

28

Proteasome subtypes and the processing of tumor antigens: increasing antigenic diversity

Nathalie Vigneron, Benoît J Van den Eynde

Journal:

Current Opinion in Immunology

Year:

2012

Language:

english

File:

PDF, 812 KB

english, 2012

29

Tum− Antigens, TSTA, and T Cell Immune Surveillance

ALINE VAN PEL, GUY WARNIER, BENOǏT VAN DEN EYNDE, BERNARD LETHÉ, CHRISTOPHE LURQUIN, THIERRY BOON

Journal:

Annals of the New York Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 557 KB

english, 1991

30

HUMAN T CELL RESPONSES AGAINST MELANOMA

Boon, Thierry, Coulie, Pierre G., Eynde, Benoît J. Van den, Bruggen, Pierre van der

Journal:

Annual Review of Immunology

Year:

2006

Language:

english

File:

PDF, 376 KB

english, 2006

31

Endosomal compartment: Also a dock for MHC class I peptide loading

Ma, Wenbin, Van den Eynde, Benoît J.

Journal:

European Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 159 KB

english, 2014

32

Intramuscular electroporation of a P1A-encoding plasmid vaccine delays P815 mastocytoma growth

Vandermeulen, Gaëlle, Uyttenhove, Catherine, De Plaen, Etienne, Van den Eynde, Benoît J., Préat, Véronique

Journal:

Bioelectrochemistry

Year:

2014

Language:

english

File:

PDF, 840 KB

english, 2014

33

Indoleamine 2,3-dioxygenase inhibitory activity of derivatives of marine alkaloid tsitsikammamine A

Dolušić, Eduard, Larrieu, Pierre, Meinguet, Céline, Colette, Delphine, Rives, Arnaud, Blanc, Sébastien, Ferain, Thierry, Pilotte, Luc, Stroobant, Vincent, Wouters, Johan, Van den Eynde, Benoît, Masere

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 955 KB

english, 2013

34

End-of-Life Care of the Geriatric Patient and Nurses’ Moral Distress

Piers, Ruth D., Van den Eynde, Magali, Steeman, Els, Vlerick, Peter, Benoit, Dominique D., Van Den Noortgate, Nele J.

Journal:

Journal of the American Medical Directors Association

Year:

2012

Language:

english

File:

PDF, 156 KB

english, 2012

35

Cyclophosphamide treatment induces rejection of established P815 mastocytoma by enhancing CD4 priming and intratumoral infiltration of P1E/H-2K d -specific CD8 + T cells

Rahir, Gwendoline, Wathelet, Nathalie, Hanoteau, Aurélie, Henin, Coralie, Oldenhove, Guillaume, Galuppo, Adrien, Lanaya, Hanane, Colau, Didier, Mackay, Charles R., Van den Eynde, Benoit, Moser, Muriel

Journal:

International Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 818 KB

english, 2014

36

Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors

Röhrig, Ute F., Majjigapu, Somi Reddy, Chambon, Marc, Bron, Sylvian, Pilotte, Luc, Colau, Didier, Van den Eynde, Benoît J., Turcatti, Gerardo, Vogel, Pierre, Zoete, Vincent, Michielin, Olivier

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.65 MB

english, 2014

37

Global Molecular Effects of Tocilizumab Therapy in Rheumatoid Arthritis Synovium

Ducreux, Julie, Durez, Patrick, Galant, Christine, Nzeusseu Toukap, Adrien, Van den Eynde, Benoît, Houssiau, Frédéric A., Lauwerys, Bernard R.

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 335 KB

english, 2014

38

N 1 -Fluoroalkyltryptophan Analogues: Synthesis and in vitro Study as Potential Substrates for Indoleamine 2,3-Dioxygenase

Henrottin, Jean, Zervosen, Astrid, Lemaire, Christian, Sapunaric, Frédéric, Laurent, Sophie, Van den Eynde, Benoit, Goldman, Serge, Plenevaux, Alain, Luxen, André

Journal:

ACS Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.52 MB

english, 2015

39

Encyclopedia of Immunology || Tumor Antigens

Van den Eynde, Benoît J.

Year:

1998

File:

PDF, 603 KB

1998

40

Proteasome Subtypes and Regulators in the Processing of Antigenic Peptides Presented by Class I Molecules of the Major Histocompatibility Complex

Vigneron, Nathalie, Van den Eynde, Benoît

Journal:

Year:

2014

Language:

english

File:

PDF, 397 KB

english, 2014

41

The capture proteasome assay: A method to measure proteasome activity in vitro

Vigneron, Nathalie, Abi Habib, Joanna, Van den Eynde, Benoît J.

Journal:

Analytical Biochemistry

Year:

2015

Language:

english

File:

PDF, 944 KB

english, 2015

42

Preclinical assessment of a novel small molecule inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1)

Driessens, Gregory, Crosignani, Stefano, Detheux, Michel, Van den Eynde, Benoît, Cauwenberghs, Sandra

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2014

Language:

english

File:

PDF, 143 KB

english, 2014

43

Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ

Put, Karen, Avau, Anneleen, Brisse, Ellen, Mitera, Tania, Put, Stéphanie, Proost, Paul, Bader-Meunier, Brigitte, Westhovens, René, Van den Eynde, Benoit J., Orabona, Ciriana, Fallarino, Francesca, De

Journal:

Year:

2015

Language:

english

File:

PDF, 800 KB

english, 2015

44

Expression profile of the human IDO1 protein, a cancer drug target involved in tumoral immune resistance

Vigneron, Nathalie, van Baren, Nicolas, Van den Eynde, Benoît J

Journal:

Year:

2015

Language:

english

File:

PDF, 376 KB

english, 2015

45

The capture proteasome assay (CAPA) to evaluate subtype-specific proteasome inhibitors

Vigneron, Nathalie, Abi Habib, Joanna, Van den Eynde, Benoît J.

Journal:

Year:

2015

Language:

english

File:

PDF, 496 KB

english, 2015

46

An antigenic peptide produced by reverse splicing and double asparagine deamidation

Alexandre Dalet, Paul F. Robbins, Vincent Stroobant, Nathalie Vigneron, Yong F. Li, Mona El-Gamil, Ken-ichi Hanada, James C. Yang, Steven A. Rosenberg and Benoît J. Van den Eynde

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 484 KB

english, 2011

47

Fully automated radiosynthesis of N1-[18F]fluoroethyl-tryptophan and study of its biological activity as a new potential substrate for indoleamine 2,3-dioxygenase PET imaging

Henrottin, Jean, Lemaire, Christian, Egrise, Dominique, Zervosen, Astrid, Van den Eynde, Benoit, Plenevaux, Alain, Franci, Xavier, Goldman, Serge, Luxen, André

Journal:

Nuclear Medicine and Biology

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

48

Characterization of T-cell Receptors Directed Against HLA-A01-restricted and C07-restricted Epitopes of MAGE-A3 and MAGE-A12

Zhu, Shigui, Van den Eynde, Benoit J., Coulie, Pierre G., Li, Yong F., El-Gamil, Mona, Rosenberg, Steven A., Robbins, Paul F.

Journal:

Journla of Immunotherapy

Year:

2012

Language:

english

File:

PDF, 448 KB

english, 2012

49

Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules

Benoît Guillaume, Jacques Chapiro, Vincent Stroobant, Didier Colau, Benoît Van Holle, Grégory Parvizi, Marie-Pierre Bousquet-Dubouch, Ivan Théate, Nicolas Parmentier, Benoît J. Van den Eynde and Peter

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.40 MB

english, 2010

50

Apolipoproteins L control cell death triggered by TLR3/TRIF signaling in dendritic cells

Uzureau, Sophie, Coquerelle, Caroline, Vermeiren, Corentin, Uzureau, Pierrick, Van Acker, Annette, Pilotte, Luc, Monteyne, Daniel, Acolty, Valérie, Vanhollebeke, Benoit, Van den Eynde, Benoît, Pérez-M

Journal:

European Journal of Immunology

Year:

2016

Language:

english

File:

PDF, 2.51 MB

english, 2016