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1

Triple-Helix Directed Cleavage of Double-Stranded DNA by Benzoquinoquinoxaline-1,10-phenanthroline Conjugates

Ahmed Zaid, Jian-Sheng Sun, Chi-Hung Nguyen, Emile Bisagni, Thérèse Garestier, David S. Grierson, Rula Zain

Journal:

Year:

2004

Language:

english

File:

PDF, 338 KB

english, 2004

2

A New Family of Sequence-Specific DNA-Cleaving Agents Directed by Triple-Helical Structures: Benzopyridoindole-EDTA Conjugates

Christophe Marchand, Chi Hung Nguyen, Brian Ward, Jian-Sheng Sun, Emile Bisagni, Thérèse Garestier, Claude Hélène

Journal:

Chemistry - A European Journal

Year:

2000

Language:

english

File:

PDF, 212 KB

english, 2000

3

4-Benzyl and 4-Benzoyl-3-dimethylaminopyridin-2(1H)-ones: In Vitro Evaluation of New C-3-Amino-Substituted and C-5,6-Alkyl-Substituted Analogues against Clinically Important HIV Mutant Strains

Benjahad, Abdellah, Croisy, Martine, Monneret, Claude, Bisagni, Emile, Mabire, Dominique, Coupa, Sophie, Poncelet, Alain, Csoka, Imre, Guillemont, Jérôme, Meyer, Christophe

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 457 KB

english, 2005

4

Characterization of a Triple Helix-specific Ligand: BePI {3-methoxy-7H-8-methyl-11-[(3′-amino)propylamino]-benzo[e]pyrido[4,3-b]indole} Intercalates into Both Double-helical and Triple-helical DNA

Daniel S. Pilch, Michael J. Waring, Jian-Sheng Sun, Michel Rougée, Chi-Hung Nguyen, Emile Bisagni, Thérèse Garestier, Claude Hélène

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 1.32 MB

1993

5

Synthesis and Binding Properties of Oligo-2‘-deoxyribonucleotides Conjugated with Triple-Helix-Specific Intercalators: Benzo[ e ] and Benzo[ g ] Pyridoindoles

Vinogradov, Serguei, Roig, Victoria, Sergueeva, Zinaida, Nguyen, Chi Hung, Arimondo, Paola, Thuong, Nguyen T., Bisagni, Emile, Sun, Jian-Sheng, Hélène, Claude, Asseline, Ulysse

Journal:

Bioconjugate Chemistry

Year:

2003

Language:

english

File:

PDF, 300 KB

english, 2003

6

Conjugates of Oligonucleotides with Triplex-Specific Intercalating Agents. Stabilization of Triple-Helical DNA in the Promoter Region of the Gene for the α-Subunit of Interleukin 2 (IL-2Rα)

Silver, Gail C., Nguyen, Chi Hung, Boutorine, Alexandre S., Bisagni, Emile, Garestier, Thérèse, Hélène, Claude

Journal:

Bioconjugate Chemistry

Year:

1997

Language:

english

File:

PDF, 362 KB

english, 1997

7

Binding of a distamycin-ellipticine hybrid molecule to DNA and chromatin: spectroscopic, biochemical, and molecular modeling investigations

Bourdouxhe, Catherine, Colson, Pierre, Houssier, Claude, Sun, Jian Sheng, Montenay-Garestier, Therese, Helene, Claude, Rivalle, Christian, Bisagni, Emile, Waring, Michael J.

Journal:

Year:

1992

Language:

english

File:

PDF, 2.04 MB

english, 1992

8

Stabilization of Triple Helical DNA by a Benzopyridoquinoxaline Intercalator †

Marchand, Christophe, Bailly, Christian, Nguyen, Chi Hung, Bisagni, Emile, Garestier, Thérèse, Hélène, Claude, Waring, Michael J.

Journal:

Year:

1996

Language:

english

File:

PDF, 815 KB

english, 1996

9

Stable Triple-Helical DNA Complexes Formed by Benzopyridoindole− and Benzopyridoquinoxaline− Oligonucleotide Conjugates

Silver, Gail C., Sun, Jian-Sheng, Nguyen, Chi Hung, Boutorine, Alexandre S., Bisagni, Emile, Hélène, Claude

Journal:

Journal of the American Chemical Society

Year:

1997

Language:

english

File:

PDF, 286 KB

english, 1997

10

Optimization of Triple-Helix-Directed DNA Cleavage by Benzoquinoquinoxaline–Ethylenediaminetetraacetic Acid Conjugates

Rula Zain, David Polverari, Chi-Hung Nguyen, Yves Blouquit, Emile Bisagni, Thérèse Garestier, David S. Grierson, Jian-Sheng Sun

Journal:

Year:

2003

Language:

english

File:

PDF, 172 KB

english, 2003

11

ChemInform Abstract: Synthesis and Antiviral Activity of 4-Benzyl Pyridinone Derivatives as Potent and Selective Non-Nucleoside Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors.

Valerie Dolle, Chi Hung Nguyen, Michel Legraverend, Anne-Marie Aubertin, Andre Kirn, Marie Line Andreola, Michel Ventura, Laura Tarrago-Litvak, Emile Bisagni

Journal:

Year:

2001

File:

PDF, 29 KB

2001

12

ChemInform Abstract: Syntheses of 4-Benzylpyridones via Nucleophilic Aromatic Substitutions.

Yves L. Janin, Christiane Huel, Michel Legraverend, Anne-Marie Aubertin, Emile Bisagni

Journal:

Year:

2002

File:

PDF, 33 KB

2002

13

Sur la formation des aldéhydes aromatiques par pyrodécomposition des aryloxyacétophénones

René Royer, Emile Bisagni

Journal:

Helvetica Chimica Acta

Year:

1959

File:

PDF, 418 KB

1959

14

Ethyl (4-N-acylaminopyridin-3-yl)glyoxylate and 5-azaisatin as new synthons for a route to various new polyheterocycles

Christian Rivalle, Emile Bisagni

Journal:

Journal of Heterocyclic Chemistry

Year:

1997

File:

PDF, 291 KB

1997

15

Aromatisation des dihydro-3,4 carbazole(2h)ones-1 par le chlorure de pyridinium

Emile Bisagni, Claire Ducrocq, Nguyen Chi Hung

Journal:

Year:

1980

File:

PDF, 406 KB

1980

16

Synthesis of new carbocyclic oxetanocin analogues

Tawfik Gharbaoui, Michel Legraverend, Odile Ludwig, Emile Bisagni, Anne-Marie Aubertin, Lyubov Chertanova

Journal:

Year:

1995

Language:

english

File:

PDF, 623 KB

english, 1995

17

Aminoalkylamino derivatives of dihydroxy-benzo[g]isoquinoline dione and of trihydroxy-naphtho[2,3-g]isoquinoline dione: synthesis and anti-tumor evaluation

Martine Croisy-Delcey, Danièle Carrez, Emile Bisagni

Journal:

European Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 671 KB

english, 1988

18

Synthesis of new non-nucleoside inhibitors of HIV-1

Valérie Dolle, Anne-Marie Aubertin, Odile Ludwig, Chi Hung Nguyen, Emile Bisagni, Michel Legraverend

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 254 KB

english, 1996

19

Synthesis of 2-oxa-4-azabicyclo[3.2.1]-octane and -octene systems via X-ray-analyzed trans-3-dibenzamido-cyclopentene-1-oxide

Michel Legraverend, Christiane Huel, Jean Guilhem, Emile Bisagni

Journal:

Carbohydrate Research

Year:

1992

Language:

english

File:

PDF, 430 KB

english, 1992

20

A formal new access to the benzo[c]phenanthridine alkaloids, synthesis of nitidine and o-methyl fagaronine analogues.

Yves L. Janin, Emile Bisagni

Journal:

Year:

1993

Language:

english

File:

PDF, 949 KB

english, 1993

21

Synthèse d'analogues tricycliques des ellipticines : les methyl-4,5h-pyrido [4,3-b] indoles (γ-carbolines) diversement substttus sur leurs sommets 1,5 et 8.

Chi Hung Nguyen, Emile Bisagni

Journal:

Year:

1987

File:

PDF, 931 KB

1987

22

Premiere synthese de methyl-4-5h- pyrido ¦3',4':4,5¦pyrrolo ¦3,2-c¦pyridines, analogues tricycliques des aza-9 ellipticines

Emile Bisagni, Nguyen Chi Hung

Journal:

Year:

1986

File:

PDF, 660 KB

1986

23

Synthese et etude de 5H-pyrido[4,3-b]-benzo[f]indoloquinones-6,11 apparentees aux ellipticines et aux anthracyclines

Christine Robaut, Christian Rivalle, Marylis Rautureau, Jean-Marc Lhoste, Emile Bisagni, Jean-Claude Chermann

Journal:

Year:

1985

File:

PDF, 736 KB

1985

24

Imidazo[1,5-g][1,4]diazepines, TIBO analogues lacking the phenyl ring: synthesis and evaluation as anti-HIV agents.

Yves L. Janin, Anne-Marie Aubertin, Angéle Chiaroni, Claude Riche, Claude Monneret, Emile Bisagni, David S. Grierson

Journal:

Year:

1996

Language:

english

File:

PDF, 1.13 MB

english, 1996

25

Studies towards 4-C-alkylation of pyridin-2(1H)-one derivatives

Valérie Dollé, Chi Hung Nguyen, Emile Bisagni

Journal:

Year:

1997

Language:

english

File:

PDF, 1002 KB

english, 1997

26

On the methylation of 3-cyano-6-hydroxypyridine-2(1H)-ones

Yves Louis Janin, Jaouad Chiki, Michel Legraverend, Christiane Huel, Emile Bisagni

Journal:

Year:

1999

Language:

english

File:

PDF, 459 KB

english, 1999

27

An efficient synthesis of 9-[(1-hydroxymethyl)-cyclubut-1-ene-3-yl] adenine and 1-(adenin-9-yl)-3-methylidene-but-1-ene-4-ol via regiospecific addition of phenyl selenenyl bromide to the alkene precursor.

Tawfik Gharbaoui, Michel Legraverend, Emile Bisagni

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 272 KB

english, 1992

28

A new route to 7-deazaguanine derivatives

Michel Legraverend, Emile Bisagni

Journal:

Tetrahedron Letters

Year:

1985

Language:

english

File:

PDF, 145 KB

english, 1985

29

Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases

Michel Legraverend, Odile Ludwig, Emile Bisagni, Sophie Leclerc, Laurent Meijer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 305 KB

english, 1998

30

Diphenyl quinolines and isoquinolines: synthesis and primary biological evaluation

Martine Croisy-Delcey, Alain Croisy, Danièle Carrez, Christiane Huel, Angèle Chiaroni, Pierre Ducrot, Emile Bisagni, Lu Jin, Guy Leclercq

Journal:

Bioorganic & Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 853 KB

english, 2000

31

Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors

Michel Legraverend, Odile Ludwig, Emile Bisagni, Sophie Leclerc, Laurent Meijer, Nicole Giocanti, Ramin Sadri, Vincent Favaudon

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 279 KB

english, 1999

32

Ligand-induced formation of Hoogsteen-paired parallel DNA

Christophe Escudé, Shahla Mohammadi, Jian-Sheng Sun, Chi-Hung Nguyen, Emile Bisagni, Jean Liquier, Eliane Taillandier, Thérèse Garestier, Claude Hélène

Journal:

Chemistry & Biology

Year:

1996

Language:

english

File:

PDF, 1.97 MB

english, 1996

33

Design of a triple-helix-specific cleaving reagent

Rula Zain, Christophe Marchand, Jian-sheng Sun, Chi Hung Nguyen, Emile Bisagni, Thérèse Garestier, Claude Hélène

Journal:

Chemistry & Biology

Year:

1999

Language:

english

File:

PDF, 149 KB

english, 1999

34

Dérivés azotés du 2-benzylfluorène et du 2-(4′-méthylbenzyl)fluorène

Ng. Ph. Buu-Hoï, René Royer, Emile Bisagni

Journal:

Recueil des Travaux Chimiques des Pays-Bas

Year:

1955

File:

PDF, 314 KB

1955

35

In vitrocytotoxicity of S16020-2, a new olivacine derivative

Stéphane Léonce, Valérie Perez, Marie-Rose Casabianca-Pignede, Monique Anstett, Emile Bisagni, Alain Pierré, Ghanem Atassi

Journal:

Investigational New Drugs

Year:

1996

Language:

english

File:

PDF, 869 KB

english, 1996

36

Antitumor activity of intoplicine (RP 60475, NSC 645008), a new benzo-pyrido-indole: evaluation against solid tumors and leukemias in mice

Marie-Christine Bissery, Chi Hung Nguyen, Emile Bisagni, Patricia Vrignaud, François Lavelle

Journal:

Investigational New Drugs

Year:

1993

Language:

english

File:

PDF, 1.05 MB

english, 1993

37

A convenient way to dibenzo[c,h]-1,5-naphthyridines (11-aza-benzo[c] phenanthridines)

Emile Bisagni, Corinne Landras, Sylvie Thirot, Christiane Huel

Journal:

Year:

1996

Language:

english

File:

PDF, 719 KB

english, 1996

38

Synthesis of psoralens and analogues

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

1992

Language:

english

File:

PDF, 1.15 MB

english, 1992

39

Autre voie d'acces aux 5h-pyrido ¦3',4':4,5¦pyrrolo ¦3,2-c¦pyridines et leur transformation en derives n-5 et n-8 substitues

Nguyen Chi Hung, Emile Bisagni

Journal:

Year:

1986

File:

PDF, 646 KB

1986

40

In Vitro Evaluation of a Novel 2,6,9-Trisubstituted Purine Acting As a Cyclin-Dependent Kinase Inhibitor

NICOLE GIOCANTI, RAMIN SADRI, MICHEL LEGRAVEREND, ODILE LUDWIG, EMILE BISAGNI, SOPHIE LECLERC, LAURENT MEIJER, VINCENT FAVAUDON

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 551 KB

english, 1999

41

Synthesis of new (.+-.)-3,5-dihydroxypentyl nucleoside analogs from 1-amino-5-(benzyloxy)pentan-3-ol and their antiviral evaluation

Legraverend, Michel, Boumchita, Hassane, Zerial, Aurelio, Huel, Christiane, Lemaitre, Marc, Bisagni, Emile

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 734 KB

english, 1990

42

Etude cinétique comparée de la substitution nucléophile de quelques chloro-2 pyridines condensées

Jean-Dominique Bourzat, El éMile Bisagni

Journal:

Journal of Heterocyclic Chemistry

Year:

1973

File:

PDF, 383 KB

1973

43

Furannes et pyrroles disubstitués en 2,3. XVI synthèse de furo[3,2-c]pyranones-4 et nouvelle voie d'accès aux furo[3,2-c]pyridines

Emile Bisagni, Alain Civier, Jean-Pierre Marquet

Journal:

Journal of Heterocyclic Chemistry

Year:

1975

File:

PDF, 323 KB

1975

44

Azaindoles. V. Pyrido(4,3-b]indoles (γ-carbolines) fonctionnalisés sur leur sommet 4: Synthèse en une seule étape

Claire Ducrocq, Alain Civier, Jeannine André-Louisfert, Emile Bisagni

Journal:

Journal of Heterocyclic Chemistry

Year:

1975

File:

PDF, 323 KB

1975

45

Preparation and characterization of a new meso-substituted tetrapyrrole macrocyclc: Meso-tetra[2-(3-carboxyethyl)furyl]porphine, [TFP]

Michel Momenteau, Bernard Loock, Emile Bisagni

Journal:

Journal of Heterocyclic Chemistry

Year:

1979

File:

PDF, 135 KB

1979

46

Nouvelle synthèse des pyrido[4,3-b]quinoléines substituées sur leur sommet 1

Christian Rivalle, Emile Bisagni

Journal:

Journal of Heterocyclic Chemistry

Year:

1980

File:

PDF, 241 KB

1980

47

Transformation thermique des β-(méthyl-2 furyl)-3 acryloylazides: Nouveau mode de formation de certaines pyrimidines

Emile Bisagni, Jean-Marc Lhoste, Nguyen Chi Hung

Journal:

Journal of Heterocyclic Chemistry

Year:

1981

Language:

french

File:

PDF, 343 KB

french, 1981

48

Synthesis of s-triazolo[4,3-b]pyridazine C-nucleosides

Michel Legraverend, Emile Bisagni, Jean-Marc Lhoste

Journal:

Journal of Heterocyclic Chemistry

Year:

1981

Language:

english

File:

PDF, 461 KB

english, 1981

49

Pseudo-nucléosides dérivés des pyrrolo[2, 3-d]pyrimidines. Synthèse et activité biologique

Michel Legraverend, Emile Bisagni, Jean-Marc Lhoste, Daniel Anker, Henri Pacheco

Journal:

Journal of Heterocyclic Chemistry

Year:

1983

File:

PDF, 363 KB

1983

50

Synthesis of 4-methylfuro[3′,2′:5,6]benzofuro[3,2-c]pyridine

Jacqueline Moron, Emile Bisagni

Journal:

Journal of Heterocyclic Chemistry

Year:

1986

Language:

english

File:

PDF, 275 KB

english, 1986