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1

Aging, Stem Cells, and Mammalian Target of Rapamycin: A Prospect of Pharmacologic Rejuvenation of Aging Stem Cells

Blagosklonny, Mikhail V.

Journal:

Rejuvenation Research

Year:

2008

Language:

english

File:

PDF, 193 KB

english, 2008

2

Rapamycin extends life- and health span because it slows aging

Blagosklonny, Mikhail V.

Journal:

Year:

2013

File:

PDF, 498 KB

2013

3

Microfluidic Endothelium for Studying the Intravascular Adhesion of Metastatic Breast Cancer Cells

Song, Jonathan W., Cavnar, Stephen P., Walker, Ann C., Luker, Kathryn E., Gupta, Mudit, Tung, Yi-Chung, Luker, Gary D., Takayama, Shuichi, Blagosklonny, Mikhail V.

Journal:

Year:

2009

File:

PDF, 914 KB

2009

4

Cancer stem cell and cancer stemloids: From biology to therapy

Blagosklonny, Mikhail V

Journal:

Cancer Biology & Therapy

Year:

2007

Language:

english

File:

PDF, 645 KB

english, 2007

5

Tissue-selective therapy of cancer

Blagosklonny, M V

Journal:

British Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 89 KB

english, 2003

6

Carcinogenesis, cancer therapy and chemoprevention

Blagosklonny, M V

Journal:

Cell Death & Differentiation

Year:

2005

Language:

english

File:

PDF, 166 KB

english, 2005

7

Target for cancer therapy: proliferating cells or stem cells

Blagosklonny, M V

Journal:

Year:

2005

Language:

english

File:

PDF, 174 KB

english, 2005

8

Paclitaxel selects for mutant or pseudo-null p53 in drug resistance associated with tubulin mutations in human cancer

Giannakakou, Paraskevi, Poy, George, Zhan, Zhirong, Knutsen, Turid, Blagosklonny, Mikhail V, Fojo, Tito

Journal:

Year:

2000

Language:

english

File:

PDF, 353 KB

english, 2000

9

An anti-aging drug today: from senescence-promoting genes to anti-aging pill

Mikhail V. Blagosklonny

Journal:

Drug Discovery Today

Year:

2007

Language:

english

File:

PDF, 346 KB

english, 2007

10

Matching targets for selective cancer therapy

Mikhail V Blagosklonny

Journal:

Drug Discovery Today

Year:

2003

Language:

english

File:

PDF, 34 KB

english, 2003

11

Antiangiogenic therapy and tumor progression

Mikhail V. Blagosklonny

Journal:

Year:

2004

Language:

english

File:

PDF, 160 KB

english, 2004

12

Revisiting antagonistic pleiotropy theory of aging: TOR-driven program and quasi-program

Blagosklonny, Mikhail V.

Journal:

Year:

2010

Language:

english

File:

PDF, 648 KB

english, 2010

13

Overcoming limitations of natural anticancer drugs by combining with artificial agents

Mikhail V. Blagosklonny

Journal:

Trends in Pharmacological Sciences

Year:

2005

Language:

english

File:

PDF, 138 KB

english, 2005

14

Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition

Blagosklonny, Mikhail V.

Journal:

Year:

2006

Language:

english

File:

PDF, 484 KB

english, 2006

15

Ionizing Radiation-Induced Oxidative Stress Alters miRNA Expression

Simone, Nicole L., Soule, Benjamin P., Ly, David, Saleh, Anthony D., Savage, Jason E., DeGraff, William, Cook, John, Harris, Curtis C., Gius, David, Mitchell, James B., Blagosklonny, Mikhail V.

Journal:

Year:

2009

Language:

english

File:

PDF, 389 KB

english, 2009

16

Resveratrol potentiates rapamycin to prevent hyperinsulinemia and obesity in male mice on high fat diet

Leontieva, O V, Paszkiewicz, G, Demidenko, Z N, Blagosklonny, M V

Journal:

Cell Death and Disease

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

17

Selective anti-cancer agents as anti-aging drugs

Blagosklonny, Mikhail V

Journal:

Cancer Biology & Therapy

Year:

2013

Language:

english

File:

PDF, 200 KB

english, 2013

18

Immunosuppressants in cancer prevention and therapy

Blagosklonny, Mikhail V

Journal:

Year:

2013

Language:

english

File:

PDF, 430 KB

english, 2013

19

Hypoxia, MTOR and autophagy

Blagosklonny, Mikhail V.

Journal:

Year:

2013

Language:

english

File:

PDF, 255 KB

english, 2013

20

Identification of a Novel Topoisomerase Inhibitor Effective in Cells Overexpressing Drug Efflux Transporters

Fayad, Walid, Fryknäs, Mårten, Brnjic, Slavica, Olofsson, Maria Hägg, Larsson, Rolf, Linder, Stig, Blagosklonny, Mikhail V.

Journal:

Year:

2009

Language:

english

File:

PDF, 683 KB

english, 2009

21

Targeted Delivery of Chemotherapy Agents Using a Liver Cancer-Specific Aptamer

Meng, Ling, Yang, Liu, Zhao, Xiangxuan, Zhang, Lucy, Zhu, Haizhen, Liu, Chen, Tan, Weihong, Blagosklonny, Mikhail V.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.86 MB

english, 2012

22

The power of chemotherapeutic engineering: Arresting cell cycle and suppressing senescence to protect from mitotic inhibitors

Blagosklonny, Mikhail V

Journal:

Year:

2011

Language:

english

File:

PDF, 1.28 MB

english, 2011

23

Calorie restriction: Decelerating mTOR-driven aging from cells to organisms (including humans)

Blagosklonny, Mikhail V

Journal:

Year:

2010

Language:

english

File:

PDF, 527 KB

english, 2010

24

Linking calorie restriction to longevity through sirtuins and autophagy: any role for TOR

Blagosklonny, M V

Journal:

Cell Death and Disease

Year:

2010

Language:

english

File:

PDF, 169 KB

english, 2010

25

Prevention of cancer by inhibiting aging

Blagosklonny, Mikhail V

Journal:

Cancer Biology & Therapy

Year:

2008

Language:

english

File:

PDF, 483 KB

english, 2008

26

Rapamycin decelerates cellular senescence

Demidenko, Zoya N., Zubova, Svetlana G., Bukreeva, Elena I., Pospelov, Valery A., Pospelova, Tatiana V., Blagosklonny, Mikhail V

Journal:

Year:

2009

Language:

english

File:

PDF, 1.33 MB

english, 2009

27

Cyclotherapy: Protection of Normal Cells and Unshielding of Cancer Cells

M. V. Blagosklonny, Z. Darzynkiewicz

Year:

2014

Language:

english

File:

PDF, 473 KB

english, 2014

28

Molecular theory of cancer

Blagosklonny, Mikhail V.

Journal:

Cancer Biology & Therapy

Year:

2005

Language:

english

File:

PDF, 746 KB

english, 2005

29

TOR-driven aging: Speeding car without brakes

Blagosklonny, Mikhail V

Journal:

Year:

2009

Language:

english

File:

PDF, 1012 KB

english, 2009

30

Hypoxia-inducible factor: Achilles' heel of antiangiogenic cancer therapy (Review)

Blagosklonny, Mikhail

Journal:

International Journal of Oncology

Year:

2001

Language:

english

File:

PDF, 1.80 MB

english, 2001

31

Conceptual Research and Phenomenology

Blagosklonny, Mikhail V.

Journal:

Year:

2003

Language:

english

File:

PDF, 310 KB

english, 2003

32

From the War on Cancer to Translational Oncology

Blagosklonny, Mikhail V.

Journal:

Cancer Biology & Therapy

Year:

2002

Language:

english

File:

PDF, 57 KB

english, 2002

33

Four Birds with One Stone: RAPA as Potential Anticancer

Blagosklonny, Mikhail V., Darzynkiewicz, Zbigniew

Journal:

Cancer Biology & Therapy

Year:

2002

Language:

english

File:

PDF, 874 KB

english, 2002

34

Aging-suppressants: Cellular senescence (hyperactivation) and its pharmacologic deceleration

Blagosklonny, Mikhail V

Journal:

Year:

2009

Language:

english

File:

PDF, 854 KB

english, 2009

35

Myocontrol in Aging

Fimbel, Eric J., Arguin, Martin, Blagosklonny, Mikhail

Journal:

Year:

2007

Language:

english

File:

PDF, 353 KB

english, 2007

36

Icariin and its Derivative Icariside II Extend Healthspan via Insulin/IGF-1 Pathway in C. elegans

Cai, Wai-Jiao, Huang, Jian-Hua, Zhang, Su-Qin, Wu, Bin, Kapahi, Pankaj, Zhang, Xin-Min, Shen, Zi-Yin, Blagosklonny, Mikhail V.

Journal:

Year:

2011

Language:

english

File:

PDF, 797 KB

english, 2011

37

From rapalogs to anti-aging formula

Blagosklonny, Mikhail V.

Journal:

Year:

2017

Language:

english

File:

PDF, 680 KB

english, 2017

38

Growth and aging: a common molecular mechanism

Blagosklonny, Mikhail V., Hall, Michael N.

Journal:

Year:

2009

Language:

english

File:

PDF, 208 KB

english, 2009

39

Rapamycin, proliferation and geroconversion to senescence

Blagosklonny, Mikhail V.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.67 MB

english, 2018

40

Answering the ultimate question “What is the Proximal Cause of Aging?”

Blagosklonny, Mikhail V.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

41

Rapamycin extends life- and health span because it slows aging

Blagosklonny, Mikhail V.

Journal:

Year:

2013

Language:

english

File:

PDF, 498 KB

english, 2013

42

Why men age faster but reproduce longer than women: mTOR and evolutionary perspectives

Blagosklonny, Mikhail V.

Journal:

Year:

2010

Language:

english

File:

PDF, 496 KB

english, 2010

43

Does rapamycin slow down time?

Blagosklonny, Mikhail V.

Journal:

Year:

2018

File:

PDF, 837 KB

2018

44

The mystery of the ketogenic diet: benevolent pseudo-diabetes

Blagosklonny, Mikhail V.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.14 MB

english, 2019

45

Hormesis does not make sense except in the light of TOR-driven aging

Blagosklonny, Mikhail V.

Journal:

Year:

2011

Language:

english

File:

PDF, 907 KB

english, 2011

46

M(o)TOR of aging: MTOR as a universal molecular hypothalamus

Blagosklonny, Mikhail V.

Journal:

Year:

2013

File:

PDF, 648 KB

2013

47

Prostate cancer cell growth inhibition by tamoxifen is associated with inhibition of protein kinase C and induction of p21waf1/cip1

Rohlff, Christian, Blagosklonny, Mikhail V., Kyle, Edward, Kesari, Anuradha, Yi Kim, Isaac, Zelner, David J., Hakim, Frances, Trepel, Jane, Bergan, Raymond C.

Journal:

Year:

1998

Language:

english

File:

PDF, 408 KB

english, 1998

48

In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug

Mikhail V. Blagosklonny, Wafik S. El-Deiry

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 849 KB

english, 1996

49

Acute overexpression of wt p53 facilitates anticancer drug-induced death of cancer and normal cells

Mikhail V. Blagosklonny, Wafik S. El-Deiry

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 300 KB

english, 1998

50

The mitogen-activated protein kinase pathway mediates growth arrest or E1A-dependent apoptosis in SKBR3 human breast cancer cells

Mikhail V. Blagosklonny

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 145 KB

english, 1998