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1

New Technologies for Analysis of Extracellular Vesicles

Shao, Huilin, Im, Hyungsoon, Castro, Cesar M., Breakefield, Xandra, Weissleder, Ralph, Lee, Hakho

Journal:

Chemical Reviews

Year:

2018

Language:

english

File:

PDF, 18.78 MB

english, 2018

2

Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A

Brunner, H., Nelen, M, Breakefield, X., Ropers, H., van Oost, B.

Journal:

Year:

1993

Language:

english

File:

PDF, 883 KB

english, 1993

3

Advances in therapeutic applications of extracellular vesicles

Wiklander, Oscar P. B., Brennan, Meadhbh Á., Lötvall, Jan, Breakefield, Xandra O., EL Andaloussi, Samir

Journal:

Science Translational Medicine

Year:

2019

Language:

english

File:

PDF, 694 KB

english, 2019

4

Therapeutic Applications of Extracellular Vesicles: Clinical Promise and Open Questions

György, Bence, Hung, Michelle E., Breakefield, Xandra O., Leonard, Joshua N.

Journal:

Annual Review of Pharmacology

Year:

2015

Language:

english

File:

PDF, 907 KB

english, 2015

5

Rapid-onset dystonia–parkinsonism: Linkage to chromosome 19q13

Patricia L. Kramer, Mari Mineta, Christine Klein, Karla Schilling, Deborah De Leon, Martin R. Farlow, Xandra O. Breakefield, Susan B. Bressman, William B. Dobyns, Laurie J. Ozelius, Allison Brashear

Journal:

Annals of Neurology

Year:

1999

Language:

english

File:

PDF, 162 KB

english, 1999

6

Localization of the gene for familial dysautonomia on chromosome 9 and definition of DNA markers for genetic diagnosis

Blumenfeld, Anat, Slaugenhaupt, Susan A., Axelrod, Felicia B., Lucente, Diane E., Maayan, Channa, Liebert, Christopher B., Ozelius, Laurie J., Trofatter, James A., Haines, Jonathan L., Breakefield, Xa

Journal:

Nature Genetics

Year:

1993

File:

PDF, 455 KB

1993

7

The human gene for neurotrophic tyrosine kinase receptor type 2 (NTRK2) is located on chromosome 9 but is not the familial dysautonomia gene

Susan A. Slaugenhaupt, Anat Blumenfeld, Christopher B. Liebert, James Mull, Diane E. Lucente, Marianne Monahan, Xandra O. Breakefield, Channa Maayan, Luis Parada, Felicia B. Axelrod, James F. Gusella

Journal:

Year:

1995

Language:

english

File:

PDF, 361 KB

english, 1995

8

Extracellular vesicles: biology and emerging therapeutic opportunities

EL Andaloussi, Samir, Mäger, Imre, Breakefield, Xandra O., Wood, Matthew J. A.

Journal:

Nature Reviews Drug Discovery

Year:

2013

Language:

english

File:

PDF, 525 KB

english, 2013

9

[Part 2: Biological Sciences] || Altered Nerve Growth Factor in Fibroblasts from Patients with Familial Dysautonomia

Joan P. Schwartz and Xandra O. Breakefield

Journal:

Proceedings of the National Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 1.16 MB

english, 1980

10

Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter

Lai, Charles P., Mardini, Osama, Ericsson, Maria, Prabhakar, Shilpa, Maguire, Casey A., Chen, John W., Tannous, Bakhos A., Breakefield, Xandra O.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.05 MB

english, 2014

11

Molecular Genetic Insights into Neurologic Diseases

Breakefield, X O, Cambi, F

Journal:

Annual Review of Neuroscience

Year:

1987

Language:

english

File:

PDF, 1.75 MB

english, 1987

12

Genetically Engineered Microvesicles Carrying Suicide mRNA/Protein Inhibit Schwannoma Tumor Growth

Mizrak, Arda, Bolukbasi, Mehmet Fatih, Ozdener, Gokhan Baris, Brenner, Gary J, Madlener, Sibylle, Erkan, Erdogan Pekcan, Ströbel, Thomas, Breakefield, Xandra O, Saydam, Okay

Journal:

Molecular Therapy

Year:

2013

Language:

english

File:

PDF, 703 KB

english, 2013

13

Exclusion of familial dysautonomia from more than 60% of the genome.

Blumenfeld, A, Axelrod, F B, Trofatter, J A, Maayan, C, Lucente, D E, Slaugenhaupt, S A, Liebert, C B, Ozelius, L J, Haines, J L, Breakefield, X O

Journal:

Journal of Medical Genetics

Year:

1993

Language:

english

File:

PDF, 992 KB

english, 1993

14

Genetics of Primary Dystonia

Klein, Christine, Breakefield, Xandra, Ozelius, Laurie

Journal:

Seminars in Neurology

Year:

1999

Language:

english

File:

PDF, 1.12 MB

english, 1999

15

Structural gene for beta-nerve growth factor not defective in familial dysautonomia.

Breakefield, X. O., Orloff, G., Castiglione, C., Coussens, L., Axelrod, F. B., Ullrich, A.

Journal:

Proceedings of the National Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 991 KB

english, 1984

16

Altered nerve growth factor in fibroblasts from patients with familial dysautonomia.

Schwartz, J. P., Breakefield, X. O.

Journal:

Proceedings of the National Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 1.16 MB

english, 1980

17

Extracellular Vesicles: Unique Intercellular Delivery Vehicles

Maas, Sybren L.N., Breakefield, Xandra O., Weaver, Alissa M.

Journal:

Trends in Cell Biology

Year:

2017

Language:

english

File:

PDF, 3.47 MB

english, 2017

18

Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

Eimer, William A., Vijaya Kumar, Deepak Kumar, Navalpur Shanmugam, Nanda Kumar, Rodriguez, Alex S., Mitchell, Teryn, Washicosky, Kevin J., György, Bence, Breakefield, Xandra O., Tanzi, Rudolph E., Moi

Journal:

Year:

2018

Language:

english

File:

PDF, 1.99 MB

english, 2018

19

Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

Eimer, William A., Vijaya Kumar, Deepak Kumar, Navalpur Shanmugam, Nanda Kumar, Rodriguez, Alex S., Mitchell, Teryn, Washicosky, Kevin J., György, Bence, Breakefield, Xandra O., Tanzi, Rudolph E., Moi

Journal:

Year:

2018

Language:

english

File:

PDF, 2.38 MB

english, 2018

20

Mutational analysis of the humanMAOA gene

Tivol, Elizabeth A., Shalish, Christo, Schuback, Deborah E., Hsu, Yun-Pung, Breakefield, Xandra O.

Journal:

American Journal of Medical Genetics

Year:

1996

Language:

english

File:

PDF, 683 KB

english, 1996

21

Combined HSV-1 recombinant and amplicon piggyback vectors: replication-competent and defective forms, and therapeutic efficacy for experimental gliomas

Peter A. Pechan, Ulrich Herrlinger, Manish Aghi, Andreas Jacobs, Xandra O. Breakefield

Journal:

The Journal of Gene Medicine

Year:

1999

Language:

english

File:

PDF, 253 KB

english, 1999

22

Prodrug activation enzymes in cancer gene therapy

Manish Aghi, Fred Hochberg, Xandra O. Breakefield

Journal:

The Journal of Gene Medicine

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

23

Hybrid vector designs to control the delivery, fate and expression of transgenes

Paula Y. P. Lam, Xandra O. Breakefield

Journal:

The Journal of Gene Medicine

Year:

2000

Language:

english

File:

PDF, 341 KB

english, 2000

24

Distribution of the mRNAs encoding torsinA and torsinB in the normal adult human brain

Sarah J. Augood, Deborah M. Martin, Laurie J. Ozelius, Xandra O. Breakefield, John B. Penney Jr, David G. Standaert

Journal:

Annals of Neurology

Year:

1999

Language:

english

File:

PDF, 2.43 MB

english, 1999

25

Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: Expanding the phenotype

Christine Klein, Peter P. Pramstaller, Bernhard Kis, Curtis C. Page, Martin Kann, Joanne Leung, Heather Woodward, Claudio C. Castellan, Monika Scherer, Peter Vieregge, Xandra O. Breakefield, Patricia

Journal:

Annals of Neurology

Year:

2000

Language:

english

File:

PDF, 330 KB

english, 2000

26

Linkage analysis in juvenile neuronal ceroid lipofuscinosis

Jonathan L. Haines, Wei-Lang Yan, Rose-Mary Boustany, Ann Jewell, Cecile Julier, Xandra O. Breakefield, James F. Gusella

Journal:

American Journal of Medical Genetics Part A

Year:

1992

Language:

english

File:

PDF, 322 KB

english, 1992

27

Role of parkin mutations in 111 community-based patients with early-onset parkinsonism

Martin Kann, Helfried Jacobs, Kathrin Mohrmann, Kirsten Schumacher, Katja Hedrich, Jennifer Garrels, Karin Wiegers, Eberhard Schwinger, Peter P. Pramstaller, Xandra O. Breakefield, Laurie J. Ozelius,

Journal:

Annals of Neurology

Year:

2002

Language:

english

File:

PDF, 1.72 MB

english, 2002

28

Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression

Khalid Shah, Emilie Bureau, Dong-Eog Kim, Katherine Yang, Yi Tang, Ralph Weissleder, Xandra O. Breakefield

Journal:

Annals of Neurology

Year:

2005

Language:

english

File:

PDF, 1.07 MB

english, 2005

29

Glial growth factor—like activity in Schwann cell tumors

Jeremy P. Brockes, Xandra O. Breakefield, Dr Robert L. Martuza

Journal:

Annals of Neurology

Year:

1986

Language:

english

File:

PDF, 622 KB

english, 1986

30

Genetic linkage studies in autosomal dominant parkinsonism: Evaluation of seven candidate genes

Dr. T. Gasser, Z. K. Wszolek, J. Trofatter, L. Ozelius, R. J. Uitti, C. S. Lee, J. Gusella, R. F. Pfeiffer, D. B. Calne, X. O. Breakefield

Journal:

Annals of Neurology

Year:

1994

Language:

english

File:

PDF, 879 KB

english, 1994

31

Dystonia in Ashkenazi Jews: Clinical characterization of a founder mutation

Dr Susan B. Bressman, Deborah de Leon, Patricia L. Kramer, Laurie J. Ozelius, Mitchell F. Brin, Paul E. Greene, Stanley Fahn, Xandra O. Breakefield, Neil J. Risch

Journal:

Annals of Neurology

Year:

1994

Language:

english

File:

PDF, 714 KB

english, 1994

32

Expression of the early-onset torsion dystonia gene (DYT1) in human brain

Sarah J. Augood, John B. Penney Jr, Ingrid K. Friberg, Xandra O. Breakefield, Anne B. Young, Laurie J. Ozelius, Dr David G. Standaert

Journal:

Annals of Neurology

Year:

1998

Language:

english

File:

PDF, 748 KB

english, 1998

33

Clinical and genetic evaluation of a family with a mixed dystonia phenotype from south tyrol

Christine Klein, Peter P. Pramstaller, Claudio C. Castellan, Xandra O. Breakefield, Patricia L. Kramer, Dr. Laurie J. Ozelius

Journal:

Annals of Neurology

Year:

1998

Language:

english

File:

PDF, 446 KB

english, 1998

34

Comparative efficacy of expression of genes delivered to mouse sensory neurons with herpes virus vectors

Dr. G. Davar, M. F. Kramer, D. Garber, A. L. Roca, J. K. Andersen, W. Bebrin, D. M. Coen, M. Kosz-Vnenchak, D. M. Knipe, X. O. Breakefield, O. Isacson

Journal:

The Journal of Comparative Neurology

Year:

1994

Language:

english

File:

PDF, 1.17 MB

english, 1994

35

Exclusion of autosomal dominant dystonia gene from large regions of chromosomes 11p, 13q, and 21q by multi-point linkage analysis

Dr. P. L. Kramer, L. Ozelius, J. F. Gusella, S. Fahn, K. K. Kidd, X. O. Breakefield, I. B. Boerecki

Journal:

Genetic Epidemiology

Year:

1987

Language:

english

File:

PDF, 599 KB

english, 1987

36

Mutations in the Norrie disease gene

Deborah E. Schuback, Zheng Yi Chen, Ian W. Craig, Xandra O. Breakefield, Katherine B. Sims

Journal:

Year:

1995

Language:

english

File:

PDF, 1000 KB

english, 1995

37

Phenylalanine hydroxylase in melanoma cells

Xandra O. Breakefield, Carmela M. Castiglione, Ruth Halaban, John Pawelek, Ross Shiman

Journal:

Journal of Cellular Physiology

Year:

1978

Language:

english

File:

PDF, 900 KB

english, 1978

38

Generation of stable retrovirus packaging cell lines after transduction with herpes simplex virus hybrid amplicon vectors

Miguel Sena-Esteves, Jürgen A. Hampl, Sara M. Camp, Xandra O. Breakefield

Journal:

The Journal of Gene Medicine

Year:

2002

Language:

english

File:

PDF, 272 KB

english, 2002

39

Cathechol-O-methyltransferase activity in cultured human skin fibroblasts from controls and patients with dystonia musculorum deformans

Xandra O. Breakefield, Muriel Braverman, Donald Kay Riker, Earl L. Giller Jr.

Journal:

Journal of Neuroscience Research

Year:

1981

Language:

english

File:

PDF, 766 KB

english, 1981

40

Gene delivery to glioma cells in rat brain by grafting of a retrovirus packaging cell line

Dr. M. P. Short, B. C. Choi, J. K. Lee, A. Malick, X. O. Breakefield, R. L. Martuza

Journal:

Journal of Neuroscience Research

Year:

1990

Language:

english

File:

PDF, 1.56 MB

english, 1990

41

Gene therapy of maliganant brain tumors: A rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells

Y. Takamiya, M. P. Short, Z. D. Ezzeddine, F. L. Moolten, Dr. X. O. Breakefield, R. L. Martuza

Journal:

Journal of Neuroscience Research

Year:

1992

Language:

english

File:

PDF, 1.32 MB

english, 1992

42

Striatal degeneration induced by mitochondrial blockade is prevented by biologically delivered NGF

D. M. Frim, J. Simpson, T. A. Uhler, M. P. Short, S. R. Bossi, X. O. Breakefield, O. Isacson

Journal:

Journal of Neuroscience Research

Year:

1993

Language:

english

File:

PDF, 787 KB

english, 1993

43

Phenotypic variability in a large kindred (Family LA) with deletions in the parkin gene

Peter P. Pramstaller, Bernhard Kis, Cordula Eskelson, Katja Hedrich, Monika Scherer, Eberhard Schwinger, Xandra O. Breakefield, Patricia L. Kramer, Laurie J. Ozelius, Christine Klein

Journal:

Movement Disorders

Year:

2002

Language:

english

File:

PDF, 108 KB

english, 2002

44

Intrafamilial phenotypic variability of the DYT1 dystonia: From asymptomatic TOR1A gene carrier status to dystonic storm

Puneet Opal, Ron Tintner, Joseph Jankovic, Joanne Leung, Xandra O. Breakefield, Jennifer Friedman, Laurie Ozelius

Journal:

Movement Disorders

Year:

2002

Language:

english

File:

PDF, 140 KB

english, 2002

45

[18F]-Dopa positron emission tomography imaging in early-stage, non-parkin juvenile parkinsonism

Pramod K. Pal, Joanne Leung, Katya Hedrich, Ali Samii, Abraham Lieberman, Paul A. Nausieda, Donald B. Calne, Xandra O. Breakefield, Christine Klein, A. Jon Stoessl

Journal:

Movement Disorders

Year:

2002

Language:

english

File:

PDF, 171 KB

english, 2002

46

Refined linkage to the RDP/DYT12 locus on 19q13.2 and evaluation of GRIK5 as a candidate gene

Christoph Kamm, Joanne Leung, Soni Joseph, William B. Dobyns, Alison Brashear, Xandra O. Breakefield, Laurie J. Ozelius

Journal:

Movement Disorders

Year:

2004

Language:

english

File:

PDF, 865 KB

english, 2004

47

Haplotype analysis at the DYT1 Locus in ashkenazi jewish patients with occupational hand dystonia

T. Gasser, C. M. Bove, L. J. Ozelius, M. Hallett, M. E. Charness, F. H. Hochberg, Dr. X. O. Breakefield

Journal:

Movement Disorders

Year:

1996

Language:

english

File:

PDF, 386 KB

english, 1996

48

A novel imaging-compatible sciatic nerve schwannoma model

Okay Saydam, Gokhan Baris Ozdener, Ozlem Senol, Arda Mizrak, Shilpa Prabhakar, Anat O. Stemmer-Rachamimov, Xandra O. Breakefield, Gary J. Brenner

Journal:

Journal of Neuroscience Methods

Year:

2011

Language:

english

File:

PDF, 469 KB

english, 2011

49

Modified herpes simplex virus delivery of enhanced GFP into the central nervous system

Vladislav M Sandler, Samuel Wang, Kamilla Angelo, Helen G Lo, Xandra O Breakefield, David E Clapham

Journal:

Journal of Neuroscience Methods

Year:

2002

Language:

english

File:

PDF, 351 KB

english, 2002

50

2020 Function of the EGR-1TIS8 radiation inducible promoter in a minimal HSV-1 amplicon system

M.A. Spear, K.M. Sakamoto, U. Herrlinger, P. Pechan, X.O. Breakefield

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1997

Language:

english

File:

PDF, 100 KB

english, 1997

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