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101

Flexible Adaptations in the Structure of the tRNA-Modifying Enzyme tRNA–Guanine Transglycosylase and Their Implications for Substrate Selectivity, Reaction Mechanism and Structure-Based Drug Design

Ruth Brenk, Milton T. Stubbs, Andreas Heine, Klaus Reuter, Gerhard Klebe

Journal:

Year:

2003

Language:

english

File:

PDF, 384 KB

english, 2003

102

Power consumption of multiple shaft agitators

Prof. Dr.-Ing. Manfred H. Pahl, Dipl.-Ing. Andreas Brenke, Bach. Yining Luo

Journal:

Chemical Engineering & Technology

Year:

1996

Language:

english

File:

PDF, 828 KB

english, 1996

103

Copper(II) Coordination Chemistry of Westiellamide and Its Imidazole, Oxazole, and Thiazole Analogues

Peter Comba, Lawrence R. Gahan, Gebhard Haberhauer, Graeme R. Hanson, Christopher J. Noble, Björn Seibold, Anna L. van den Brenk

Journal:

Chemistry - A European Journal

Year:

2008

Language:

english

File:

PDF, 526 KB

english, 2008

104

ChemInform Abstract: Conformational Control by Thiazole and Oxazoline Rings in Cyclic Octapeptides of Marine Origin. Novel Macrocyclic Chair and Boat Conformations.

G. ABBENANTE, D. P. FAIRLIE, L. R. GAHAN, G. R. HANSON, G. K. PIERENS, A. L. VAN DEN BRENK

Journal:

Year:

1997

File:

PDF, 29 KB

1997

105

ChemInform Abstract: De Novo Design, Synthesis, and in vitro Evaluation of Inhibitors for Prokaryotic tRNA-Guanine Transglycosylase: A Dramatic Sulfur Effect on Binding Affinity.

Emmanuel A. Meyer, Ruth Brenk, Ronald K. Castellano, Maya Furler, Gerhard Klebe, Francois Diederich

Journal:

Year:

2002

File:

PDF, 26 KB

2002

106

Lessons Learnt from Assembling Screening Libraries for Drug Discovery for Neglected Diseases

Ruth Brenk, Alessandro Schipani, Daniel James, Agata Krasowski, Ian Hugh Gilbert, Julie Frearson, Paul Graham Wyatt

Journal:

Year:

2008

Language:

english

File:

PDF, 603 KB

english, 2008

107

Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1

Daniel Spinks, Dr. Han B. Ong, Dr. Chidochangu P. Mpamhanga, Dr. Emma J. Shanks, Dr. David A. Robinson, Iain T. Collie, Dr. Kevin D. Read, Prof. Julie A. Frearson, Prof. Paul G. Wyatt, Dr. Ruth Brenk,

Journal:

Year:

2011

Language:

english

File:

PDF, 526 KB

english, 2011

108

Optimisation of the Anti-Trypanosoma brucei Activity of the Opioid Agonist U50488

Victoria C. Smith, Dr. Laura A. T. Cleghorn, Dr. Andrew Woodland, Daniel Spinks, Irene Hallyburton, Iain T. Collie, Dr. N. Yi Mok, Suzanne Norval, Dr. Ruth Brenk, Prof. Alan H. Fairlamb, Prof. Julie A

Journal:

Year:

2011

Language:

english

File:

PDF, 291 KB

english, 2011

109

From Hit to Lead: De Novo Design Based on Virtual Screening Hits of Inhibitors of tRNA-Guanine Transglycosylase, a Putative Target of Shigellosis Therapy

Ruth Brenk, Hans-Dieter Gerber, Jeffrey D. Kittendorf, George A. Garcia, Klaus Reuter, Gerhard Klebe

Journal:

Helvetica Chimica Acta

Year:

2003

Language:

english

File:

PDF, 299 KB

english, 2003

110

Synthesis and In Vitro Evaluation of 2-Aminoquinazolin-4(3H)-one-Based Inhibitors for tRNA-Guanine Transglycosylase (TGT)

Emmanuel A. Meyer, Maya Furler, François Diederich, Ruth Brenk, Gerhard Klebe

Journal:

Helvetica Chimica Acta

Year:

2004

Language:

english

File:

PDF, 395 KB

english, 2004

111

Synthesis, Biological Evaluation, and Crystallographic Studies of Extended Guanine-Based (lin-Benzoguanine) Inhibitors for tRNA-Guanine Transglycosylase (TGT)

Emmanuel A. Meyer, Nicola Donati, Marine Guillot, W. Bernd Schweizer, François Diederich, Bernhard Stengl, Ruth Brenk, Klaus Reuter, Gerhard Klebe

Journal:

Helvetica Chimica Acta

Year:

2006

Language:

english

File:

PDF, 769 KB

english, 2006

112

Binding of copper(II) to the cyclic octapeptide, patellamide D.

A.L.van den Brenk, G.R. Hanson, C.J. Hawkins

Journal:

Journal of Inorganic Biochemistry

Year:

1989

Language:

english

File:

PDF, 81 KB

english, 1989

113

Identification of molybdenum in marine ascidians

A.L. van den Brenk, V. Grillo, G.R. Hanson, C.J. Hawkins

Journal:

Journal of Inorganic Biochemistry

Year:

1991

Language:

english

File:

PDF, 31 KB

english, 1991

114

Mood questionaire in quality of life measurement: metrics evaluation

Rok Accetto, Klas M. Brenk

Journal:

Patient Education and Counseling

Year:

1994

Language:

english

File:

PDF, 92 KB

english, 1994

115

Virtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase

Gian Filippo Ruda, Gordon Campbell, Vincent P. Alibu, Michael P. Barrett, Ruth Brenk, Ian H. Gilbert

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

116

Identification of novel inhibitors of UDP-Glc 4′-epimerase, a validated drug target for african sleeping sickness

Michael D. Urbaniak, Jioji N. Tabudravu, Aichi Msaki, Kathy Mansfield Matera, Ruth Brenk, Marcel Jaspars, Michael A.J. Ferguson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 225 KB

english, 2006

117

Novel Ligands for a Purine Riboswitch Discovered by RNA-Ligand Docking

Peter Daldrop, Francis E. Reyes, David A. Robinson, Colin M. Hammond, David M. Lilley, Robert T. Batey, Ruth Brenk

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 807 KB

english, 2011

118

Formation of mononuclear and chloro-bridged binuclear copper(II) complexes of patellamide D, a naturally occurring cyclic peptide: influence of anion and solvent

Anna L. van den Brenk, Joel D.A. Tyndall, Rodney M. Cusack, Alun Jones, David P. Fairlie, Lawrence R. Gahan, Graeme R. Hanson

Journal:

Journal of Inorganic Biochemistry

Year:

2004

Language:

english

File:

PDF, 624 KB

english, 2004

119

Synthesis of β-1,4-di-d-mannuronic acid glycosides as potential ligands for toll-like receptors

Zi-Hua Jiang, Rongsong Xu, Charlene Wilson, Agnes Brenk

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 135 KB

english, 2007

120

Feasibility of Contrast-Enhanced Sonography During Resection of Cerebral Tumours: Initial Results of a Prospective Study

Martin Engelhardt, Christian Hansen, Jens Eyding, Wilko Wilkening, Christopher Brenke, Christos Krogias, Martin Scholz, Albrecht Harders, Helmut Ermert, Kirsten Schmieder

Journal:

Ultrasound in Medicine & Biology

Year:

2007

Language:

english

File:

PDF, 1.03 MB

english, 2007

121

PIPER: An FFT-based protein docking program with pairwise potentials

Dima Kozakov, Ryan Brenke, Stephen R. Comeau, Sandor Vajda

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2006

Language:

english

File:

PDF, 386 KB

english, 2006

122

Docking with PIPER and refinement with SDU in rounds 6–11 of CAPRI

Yang Shen, Ryan Brenke, Dima Kozakov, Stephen R. Comeau, Dmitri Beglov, Sandor Vajda

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 274 KB

english, 2007

123

ClusPro: Performance in CAPRI rounds 6–11 and the new server

Stephen R. Comeau, Dima Kozakov, Ryan Brenke, Yang Shen, Dmitri Beglov, Sandor Vajda

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 213 KB

english, 2007

124

Structural insights into recognition of β2-glycoprotein I by the lipoprotein receptors

Dmitri Beglov, Chang-Jin Lee, Alfredo De Biasio, Dima Kozakov, Ryan Brenke, Sandor Vajda, Natalia Beglova

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2009

Language:

english

File:

PDF, 419 KB

english, 2009

125

Achieving reliability and high accuracy in automated protein docking: Cluspro, PIPER, SDU, and stability analysis in CAPRI rounds 13–19

Dima Kozakov, David R. Hall, Dmitri Beglov, Ryan Brenke, Stephen R. Comeau, Yang Shen, Keyong Li, Jiefu Zheng, Pirooz Vakili, Ioannis Ch. Paschalidis, Sandor Vajda

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2010

Language:

english

File:

PDF, 298 KB

english, 2010

126

Minimal ensembles of side chain conformers for modeling protein–protein interactions

Dmitri Beglov, David R. Hall, Ryan Brenke, Maxim V. Shapovalov, Roland L. Dunbrack Jr., Dima Kozakov, Sandor Vajda

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2012

Language:

english

File:

PDF, 1.57 MB

english, 2012

127

Virulence ofEscherichia colistrains isolated from urine of patients with acute cystitis and from faeces of healthy women

J. F. van den Bosch, P. Postma, D. van Brenk, P. A. M. Guinée, J. de Graaff, D. M. MacLaren

Journal:

Antonie van Leeuwenhoek

Year:

1981

Language:

english

File:

PDF, 520 KB

english, 1981

128

Unemployed — and unwilling to work?

Journal:

Economic Bulletin

Year:

2002

Language:

english

File:

PDF, 1.28 MB

english, 2002

129

In vivo measurements of the internal pH of Hediste (Nereis) diversicolor (Annelida, Polychaeta) exposed to ambient sulphidic conditions using pH microelectrodes

Stefan Sommer, Andreas Jahn, Friederike Funke, Nils Brenke

Journal:

Naturwissenschaften (The Science of Nature)

Year:

2000

Language:

english

File:

PDF, 123 KB

english, 2000

130

Non-interferometric transient quantitative phase microscopy for

Alexander Horn, Ilja Mingareev, Alexander Werth, Martin Kachel, Udo Brenk

Journal:

Applied Physics A: Materials Science & Processing

Year:

2008

Language:

english

File:

PDF, 824 KB

english, 2008

131

Investigations on ultrafast welding of glass–glass and glass–silicon

Alexander Horn, Ilja Mingareev, Alexander Werth, Martin Kachel, Udo Brenk

Journal:

Applied Physics A: Materials Science & Processing

Year:

2008

Language:

english

File:

PDF, 912 KB

english, 2008

132

Interaction of dielectrics with femtosecond laser pulses: application of kinetic approach and multiple rate equation

B. Rethfeld, O. Brenk, N. Medvedev, H. Krutsch, D. H. H. Hoffmann

Journal:

Applied Physics A: Materials Science & Processing

Year:

2010

Language:

english

File:

PDF, 414 KB

english, 2010

133

High specificity of myositis specific autoantibodies for myositis compared with other neuromuscular disorders

G. J. D. Hengstman, L. van Brenk, W. T. M. Vree Egberts, E. L. van der Kooi, G. F. Borm, G. W. A. M. Padberg, W. J. van Venrooij, B. G. M. van Engelen

Journal:

Journal of Neurology

Year:

2005

Language:

english

File:

PDF, 218 KB

english, 2005

134

An Eulerian approach for partitioned fluid–structure simulations on Cartesian grids

Miriam Mehl, Markus Brenk, Hans-Joachim Bungartz, Klaus Daubner, Ioan Lucian Muntean, Tobias Neckel

Journal:

Computational Mechanics

Year:

2008

Language:

english

File:

PDF, 1.00 MB

english, 2008

135

Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase

Melissa R. Landon, Raquel L. Lieberman, Quyen Q. Hoang, Shulin Ju, Jose M. M. Caaveiro, Susan D. Orwig, Dima Kozakov, Ryan Brenke, Gwo-Yu Chuang, Dmitry Beglov, Sandor Vajda, Gregory A. Petsko, Dagmar

Journal:

Journal of Computer-Aided Molecular Design

Year:

2009

Language:

english

File:

PDF, 574 KB

english, 2009

136

Seltene Ursache einer gastrointestinalen Blutung

S. De Filippo, J. Kunz, D. Brenke, B. Köhrer, A. Lutterer, L. Goßner

Journal:

Der Gastroenterologe

Year:

2011

Language:

german

File:

PDF, 468 KB

german, 2011

137

Cycloxazoline: A cytotoxic cyclic hexapeptide from the ascidian lissoclinum bistratum.

Trevor W. Hambley, Clifford J. Hawkins, Martin F. Lavin, Anna van den Brenk, Diane J. Watters

Journal:

Year:

1992

Language:

english

File:

PDF, 449 KB

english, 1992

138

A phylogeny of anisopterous dragonflies (Insecta, Odonata) using mtRNA genes and mixed nucleotide/doublet models

G. Fleck, B. Ullrich, M. Brenk, C. Wallnisch, M. Orland, S. Bleidissel, B. Misof

Journal:

Journal of Zoological Systematics and Evolutionary Research

Year:

2008

Language:

english

File:

PDF, 502 KB

english, 2008

139

Radiation Lethality and Local Tissue Damage in Histamine-depleted Rats

VAN DEN BRENK, H. A. S.

Journal:

Year:

1957

File:

PDF, 111 KB

1957

140

Radioprotective Action of 5-Hydroxy-tryptamine

VAN DEN BRENK, H. A. S., ELLIOTT, KATHLEEN

Journal:

Year:

1958

File:

PDF, 212 KB

1958

141

Effect of High Oxygen Pressure on the Protective Action of Cystamine and 5-Hydroxytryptamine in Irradiated Rats

VAN DEN BRENK, H. A. S., MOORE, RUTH

Journal:

Year:

1959

File:

PDF, 223 KB

1959

142

Effect of Electrode Dimensions on Tissue pO2 Measurement in vivo

JAMIESON, DANA, VAN DEN BRENK, H. A. S.

Journal:

Year:

1964

File:

PDF, 388 KB

1964

143

Effect of Oxygen Pressure on Radiosensitivity of Ehrlich Ascites Tumours at Various Intervals after Inoculation

van den BRENK, H. A. S., SPARROW, NANCY

Journal:

Year:

1965

File:

PDF, 436 KB

1965

144

Actions and interactions of colchicine and cytochalasin B on contraction of granulation tissue and on mitosis

VAN DEN BRENK, H. A. S., STONE, M. G.

Journal:

Year:

1974

File:

PDF, 325 KB

1974

145

Studies of the Effect of a Colloidal Radioactive Chromic Phosphate (Cr32PO4) in Clinical and Experimental Malignant Effusions

van den Brenk, H A S, Clarke, K H, Holman, W P, Winkler, Carmyl

Journal:

British Journal of Cancer

Year:

1959

Language:

english

File:

PDF, 1.35 MB

english, 1959

146

Effect of Immunological Attenuation on Cell Dosage Required to Establish Single or Double Tumour Homografts

van den Brenk, H A S

Journal:

British Journal of Cancer

Year:

1961

Language:

english

File:

PDF, 700 KB

english, 1961

147

Effect of Single and Fractionated Doses of X-rays on Radiocurability of Solid Ehrlich Tumour and Tissue Reactions In Vivo, for Different Oxygen Tensions

van den Brenk, H A S, Elliott, Kathleen, Hutchings, Hilary

Journal:

British Journal of Cancer

Year:

1962

Language:

english

File:

PDF, 1.91 MB

english, 1962

148

Effect of High Pressure Oxygen on Radiosensitivity of Ehrlich's Tumour in Mice After “Immunological Approximation”

van den Brenk, H A S

Journal:

British Journal of Cancer

Year:

1961

Language:

english

File:

PDF, 3.99 MB

english, 1961

149

Comparison of Oxygen Tensions in Normal Tissues and Yoshida Sarcoma of the Rat Breathing Air or Oxygen at 4 Atmospheres

Jamieson, Dana, van den Brenk, H A S

Journal:

British Journal of Cancer

Year:

1963

Language:

english

File:

PDF, 2.67 MB

english, 1963

150

Further Observations on Radiocurability of a Solid Ehrlich Tumour and Tissue Reactions in the Mouse with Fractionated Radiation Doses and the Effects of Oxygen

van den Brenk, H A S, Elliott, Kathleen, Hutchings, Hilary

Journal:

British Journal of Cancer

Year:

1963

Language:

english

File:

PDF, 623 KB

english, 1963