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1

Selective uptake of ricin A-chain by hepatic non-parenchymal cells in vitro: Importance of mannose oligosaccharides in the toxin

David N. Skilleter, Brian M.J. Foxwell

Journal:

Year:

1986

Language:

english

File:

PDF, 424 KB

english, 1986

2

The role of Toll-like receptors in chronic inflammation

Stefan K. Drexler, Brian M. Foxwell

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2010

Language:

english

File:

PDF, 755 KB

english, 2010

3

IL-10-mediated suppression of TNF-α production is independent of its ability to inhibit NFκB activity

Christopher J. P. Clarke, Anne Hales, Abigail Hunt, Brian M. J. Foxwell

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 178 KB

english, 1998

4

The gp200-MR6 molecule which is functionally associated with the IL-4 receptor modulates B cell phenotype and is a novel member of the human macrophage mannose receptor family

Paul F. McKay, Nesrina Imami, Michael Johns, David A. Taylor-Fishwick, Lucas M. Sedibane, Nicholas F. Totty, J. Justin Hsuan, Donald B. Palmer, Andrew J. T. George, Brian M. J. Foxwell, Mary A. Ritter

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 274 KB

english, 1998

5

Role of NFκB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI

Satomichi Yoshimura, Jan Bondeson, Fionula M. Brennan, Brian M.J. Foxwell, Marc Feldmann

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 205 KB

english, 2001

6

TNFα-induced macrophage chemokine secretion is more dependent on NF-κB expression than lipopolysaccharides-induced macrophage chemokine secretion

Cathleen J. Ciesielski, Evangelos Andreakos, Brian M. J. Foxwell, Marc Feldmann

Journal:

European Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 239 KB

english, 2002

7

Evidence that rheumatoid arthritis synovial T cells are similar to cytokine-activated T cells: Involvement of phosphatidylinositol 3-kinase and nuclear factor κB pathways in tumor necrosis factor α production in rheumatoid arthritis

Fionula M. Brennan, Amanda L. Hayes, Cathleen J. Ciesielski, Patricia Green, Brian M. J. Foxwell, Marc Feldmann

Journal:

Arthritis & Rheumatism

Year:

2002

Language:

english

File:

PDF, 175 KB

english, 2002

8

Heterogeneous requirement of IκB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: Implications for therapy

Evangelos Andreakos, Clive Smith, Serafim Kiriakidis, Claudia Monaco, Rainer de Martin, Fionula M. Brennan, Ewa Paleolog, Marc Feldmann, Brian M. Foxwell

Journal:

Arthritis & Rheumatism

Year:

2003

Language:

english

File:

PDF, 389 KB

english, 2003

9

SIGIRR/TIR-8 is an inhibitor of toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis

Stefan K. Drexler, Philip Kong, Julia Inglis, Richard O. Williams, Cecilia Garlanda, Alberto Mantovani, Amir S. Yazdi, Fionula Brennan, Marc Feldmann, Brian M. J. Foxwell

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 854 KB

english, 2010

10

Inhibitors of p38 suppress cytokine production in rheumatoid arthritis synovial membranes: Does variable inhibition of interleukin-6 production limit effectiveness in vivo?

Theresa H. Page, Anthony Brown, Emma M. Timms, Brian M. J. Foxwell, Keith P. Ray

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 528 KB

english, 2010

11

Identification of interleukin 4 receptor-associated proteins and expression of both high- and low-affinity binding on human lymphoid cells

Brian M. J. Foxwell, Gaetane Woerly, Bernhard Ryffel

Journal:

European Journal of Immunology

Year:

1989

Language:

english

File:

PDF, 875 KB

english, 1989

12

Inhibition of interleukin 4 receptor expression on human lymphoid cells by cyclosporin

Brian M. J. Foxwell, Gaetane Woerly, Bernhard Ryffel

Journal:

European Journal of Immunology

Year:

1990

Language:

english

File:

PDF, 702 KB

english, 1990

13

Interleukin 4 induces interleukin 6 production by endothelial cells: Synergy with interferon-γ

Gareth Howells, Phuong Pham, David Taylor, Brian Foxwell, Marc Feldmann

Journal:

European Journal of Immunology

Year:

1991

Language:

english

File:

PDF, 436 KB

english, 1991

14

Cloning, expression and cross-linking analysis of the murine p55 tumor necrosis factor receptor

Kathy Barrett, David A. Taylor-Fishwick, Andrew P. Cope, A. Maija Kissonerghis, Patrick W. Gray, Marc Feldmann, Brian M. J. Foxwell

Journal:

European Journal of Immunology

Year:

1991

Language:

english

File:

PDF, 866 KB

english, 1991

15

Inhibition of activation-induced changes in the structure of the T cell interleukin-7 receptor by cyclosporin A and FK506

Brian M. J. Foxwell, Joanie L. Willcocks, David A. Taylor-Fishwick, Kimary Kulig, Bernhard Ryffel, Marco Londei

Journal:

European Journal of Immunology

Year:

1993

Language:

english

File:

PDF, 780 KB

english, 1993

16

The murine T cell line CT6 provides a novel bioassay for interleukin-7

Joanie L. Willcocks, Anne Hales, Theresa H. Page, Brian M. J. Foxwell

Journal:

European Journal of Immunology

Year:

1993

Language:

english

File:

PDF, 515 KB

english, 1993

17

Interleukin-7 activates p56lck and p59fyn, two tyrosine kinases associated with the p90 interleukin-7 receptor in primary human T cells

Theresa H. Page, Ferdinand V. Lali, Brian M. J. Foxwell

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 750 KB

english, 1995

18

Interleukin-4 inhibits χ light chain expression and NFχB activation but not IχBα degradation in 70Z/3 murine pre-B cells

Christopher J. P. Clarke, David A. Taylor-Fishwick, Anne Hales, Yuti Chernajovsky, Kazuo Sugamura, Marc Feldmann, Brian M. J. Foxwell

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 721 KB

english, 1995

19

Interleukin-7 can induce the activation of Jak 1, Jak 3 and STAT 5 proteins in murine T cells

Brian M. J. Foxwell, Carol Beadling, Dimitri Guschin, Ian Kerr, Doreen Cantrell

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 748 KB

english, 1995

20

Interleukin-7 induces T cell proliferation in the absence of Erk/MAP kinase activity

James B. Crawley, Joannie Willcocks, Brian M. J. Foxwell

Journal:

European Journal of Immunology

Year:

1996

Language:

english

File:

PDF, 782 KB

english, 1996

21

Interleukin-7 activates human naive CD4+ cells and primes for interleukin-4 production

Louise M. C. Webb, Brian M. Foxwell, Marc Feldmann

Journal:

European Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 821 KB

english, 1997

22

Synergistic enhancement of Toll-like receptor responses by NOD1 activation

David A. van Heel, Subrata Ghosh, Matt Butler, Karen Hunt, Brian Michael J. Foxwell, Dominique Mengin-Lecreulx, Raymond J. Playford

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 221 KB

english, 2005

23

RelB/p50 regulates CCL19 production, but fails to promote human DC maturation

Chiara Gasparini, Brian M. J. Foxwell, Marc Feldmann

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 250 KB

english, 2009

24

Reporter gene assay demonstrates functional differences in estrogen receptor activity in purified breast cancer cells: A pilot study

Anjana Singh, Simak Ali, Manish S. Kothari, Manuela Tamburo De Bella, Clive Smith, Emma Timms, Martin J. Slade, Brian M. Foxwell, R. Charles Coombes

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 160 KB

english, 2003

25

The chemical plant manufacturer in relation to chemical industry

G. E. Foxwell, Brian N. Reavell

Journal:

Journal of Chemical Technology & Biotechnology

Year:

1939

Language:

english

File:

PDF, 743 KB

english, 1939

26

The chemical plant manufacturer in relation to chemical industry

Brian N. Reavell, DR. G. E. Foxwell

Journal:

Journal of Chemical Technology & Biotechnology

Year:

1940

Language:

english

File:

PDF, 218 KB

english, 1940

27

TNF is here to stay!

Fran Balkwill, Brian Foxwell, Fionula Brennan

Journal:

Immunology Today

Year:

2000

Language:

english

File:

PDF, 173 KB

english, 2000

28

Inhibition of endotoxin-induced TNF-α production in macrophages by 5Z-7-oxo-zeaenol and other fungal resorcylic acid lactones

Philip Rawlins, Thomas Mander, Roya Sadeghi, Simon Hill, Guy Gammon, Brian Foxwell, Stephen Wrigley, Michael Moore

Journal:

International Journal of Immunopharmacology

Year:

1999

Language:

english

File:

PDF, 217 KB

english, 1999

29

Is targeting Toll-like receptors and their signaling pathway a useful therapeutic approach to modulating cytokine-driven inflammation?

Evangelos Andreakos, Brian Foxwell, Marc Feldmann

Journal:

Immunological Reviews

Year:

2004

Language:

english

File:

PDF, 494 KB

english, 2004

30

Interleukin-10 suppression of myeloid cell activation — a continuing puzzle

Lynn M. Williams, Giuseppe Ricchetti, Usha Sarma, Timothy Smallie, Brian M. J. Foxwell

Journal:

Year:

2004

Language:

english

File:

PDF, 312 KB

english, 2004

31

Jund is a determinant of macrophage activation and is associated with glomerulonephritis susceptibility

Behmoaras, Jacques, Bhangal, Gurjeet, Smith, Jennifer, McDonald, Kylie, Mutch, Brenda, Lai, Ping Chin, Domin, Jan, Game, Laurence, Salama, Alan, Foxwell, Brian M

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 327 KB

english, 2008

32

Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1

Valerie Albrecht, Thomas PJ Hofer, Brian Foxwell, Marion Frankenberger, Loems Ziegler-Heitbrock

Journal:

Year:

2008

Language:

english

File:

PDF, 413 KB

english, 2008

33

Blockade of the galactose-binding sites of ricin by its linkage to antibody : Specific cytotoxic effects of the conjugates

Philip E. THORPE, Walter C. J. ROSS, Alex N. F. BROWN, Christopher D. MYERS, Alan J. CUMBER, Brian M. J. FOXWELL, J. Tony FORRESTER

Journal:

Year:

1984

Language:

english

File:

PDF, 1.00 MB

english, 1984

34

Modification of the carbohydrate in ricin with metaperiodate — cyanoborohydride mixtures : Effects on toxicity and in vivo distribution

Philip E. THORPE, Simone I. DETRE, Brian M. J. FOXWELL, Alex N. F. BROWN, David N. SKILLETER, Glynn WILSON, J. Anthony FORRESTER, Fiorenzo STIRPE

Journal:

Year:

1985

Language:

english

File:

PDF, 1018 KB

english, 1985

35

POTENTIATION OF TNF-α TOXICITY BY CONJUGATION WITH RICIN A-CHAIN

David J Gould, Brian M.J Foxwell, Marc Feldmann, Yuti Chernajovsky

Journal:

Year:

1998

Language:

english

File:

PDF, 167 KB

english, 1998

36

INTERLEUKIN 10 MODULATION OF TUMOUR NECROSIS FACTOR RECEPTORS REQUIRES TYROSINE KINASES BUT NOT THE PI 3-KINASE/p70 S6 KINASE PATHWAY

Lynn Williams, Ferdinand Lali, Christopher Clarke, Fionula Brennan, Brian Foxwell

Journal:

Year:

2000

Language:

english

File:

PDF, 589 KB

english, 2000

37

IL-4 REGULATION OF p38 MAPK SIGNALLING IS DEPENDENT ON CELL TYPE

Abigail E. Hunt, Lynn M. Williams, Ferdinand V. Lali, Brian M.J. Foxwell

Journal:

Year:

2002

Language:

english

File:

PDF, 519 KB

english, 2002

38

Identification of cyclophilin as the erythrocyte ciclosporin-binding protein

Brian M.J. Foxwell, Giles Frazer, Marijlein Winters, Peter Hiestand, Roland Wenger, Bernhard Ryffel

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1988

Language:

english

File:

PDF, 936 KB

english, 1988

39

Covalent binding of cyclosporine inhibits irreversibly T-lymphocyte activation

Bernhard Ryffel, Gaëtane Woerly, Valérie F.J. Quesniaux, Holger Husi, Brian M.J. Foxwell

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.06 MB

english, 1992

40

Differential regulation of tumour necrosis factor receptors (TNF-R) by IL-4; upregulation of P55 and P75 TNF-R on synovial joint mononuclear cells

Andrew P. Cope, Deena L. Gibbons, Dan Aderka, Brian M. Foxwell, David Wallach, Ravinder N. Maini, Marc Feldmann, Fionula M. Brennan

Journal:

Year:

1993

Language:

english

File:

PDF, 784 KB

english, 1993

41

TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells

Devang N. Patel, Steven R. Bailey, John K. Gresham, David B. Schuchman, James H. Shelhamer, Barry J. Goldstein, Brian M. Foxwell, Michael B. Stemerman, Jodi K. Maranchie, Anthony J. Valente, Srinivas

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 852 KB

english, 2006

42

Bmx regulates LPS-induced IL-6 and VEGF production via mRNA stability in rheumatoid synovial fibroblasts

Christine D. Palmer, Brenda E. Mutch, Theresa H. Page, Nicole J. Horwood, Brian M.J. Foxwell

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 220 KB

english, 2008

43

132 Toll-like Receptors (TLRS) Contribute in the Inflammation and Pathogenesis of RA

Sandra Sacre, Alexandra Lo, Mino Medghalchi, Bernard Gregory, Lynn Williams, Fionula Brennan, Richard Williams, Brian Foxwell

Journal:

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

44

116 Treatment with Non-steroidal Anti-inflammatory Drugs Increases TNF Production in Rheumatoid Arthritis

Theresa H. Page, Anthony C. Brown, Emma M. Timms, Fionula M. Brennan, Keith P. Ray, Brian M.J. Foxwell

Journal:

Year:

2007

Language:

english

File:

PDF, 49 KB

english, 2007

45

176 Identification of a novel enhancer region in the distal promoter region of the human interferon-lambda1 gene

Scott J.P. Thomson, FuiGoon Goh, Helen Banks, Brian Foxwell, Sergei V. Kotenko, Irina A. Udalova

Journal:

Year:

2008

Language:

english

File:

PDF, 46 KB

english, 2008

46

Anti-TNF therapy: Where have we got to in 2005?

Marc Feldmann, Fionula M. Brennan, Brian M.J. Foxwell, Peter C. Taylor, Richard O. Williams, R.N. Maini

Journal:

Journal of Autoimmunity

Year:

2005

Language:

english

File:

PDF, 83 KB

english, 2005

47

Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages

Maria J. Smolinska, Nicole J. Horwood, Theresa H. Page, Tim Smallie, Brian M.J. Foxwell

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 1.05 MB

english, 2008

48

Rac mediates TNF-induced cytokine production via modulation of NF-κB

Lynn M. Williams, Ferdinand Lali, Kate Willetts, Cristina Balague, Nuria Godessart, Fionula Brennan, Marc Feldmann, Brian M.J. Foxwell

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 669 KB

english, 2008

49

Role of STAT3 in glucocorticoid-induced expression of the human IL-10 gene

Claudia Unterberger, Karl J. Staples, Timothy Smallie, Lynn Williams, Brian Foxwell, Annette Schaefer, Bettina Kempkes, T.P.J. Hofer, Max Koeppel, Marion Lohrum, Henk Stunnenberg, Marion Frankenberger

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 735 KB

english, 2008

50

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

David A van Heel, Subrata Ghosh, Matt Butler, Karen A Hunt, Anna MC Lundberg, Tariq Ahmad, Dermot PB McGovern, Clive Onnie, Kenichi Negoro, Sue Goldthorpe, Brian MJ Foxwell, Christopher G Mathew, Alas

Journal:

Year:

2005

Language:

english

File:

PDF, 155 KB

english, 2005