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51

Close encounters for the first time: Helicase interactions with DNA damage

Khan, Irfan, Sommers, Joshua A., Brosh, Robert M.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.91 MB

english, 2015

52

Physical and Functional Mapping of the Replication Protein A Interaction Domain of the Werner and Bloom Syndrome Helicases

Doherty, Kevin M., Sommers, Joshua A., Gray, Matthew D., Lee, Jae Wan, von Kobbe, Cayetano, Thoma, Nicolas H., Kureekattil, Raichal P., Kenny, Mark K., Brosh, Robert M.

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 887 KB

english, 2005

53

Genetic mutants illuminate the roles of RecQ helicases in recombinational repair or response to replicational stress

Aggarwal, Monika, Brosh, Robert M.

Journal:

Year:

2010

Language:

english

File:

PDF, 747 KB

english, 2010

54

Targeting an Achilles’ heel of cancer with a WRN helicase inhibitor

Aggarwal, Monika, Banerjee, Taraswi, Sommers, Joshua A, Brosh, Jr, Robert M

Journal:

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

55

UvrD helicase: The little engine that could

Brosh, Jr., Robert M.

Journal:

Year:

2014

Language:

english

File:

PDF, 855 KB

english, 2014

56

Helicases as Prospective Targets for Anti-Cancer Therapy

Gupta, Rigu, Brosh, Jr., Robert

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 298 KB

english, 2008

57

Mechanistic and biological aspects of helicase action on damaged DNA

Suhasini, Avvaru N., Brosh, Robert M.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.83 MB

english, 2010

58

Finding a needle in the haystack: Recognition of DNA damage by collaboration between DNA repair proteins able to perform DNA charge transport

Brosh, Robert M.

Journal:

Year:

2012

Language:

english

File:

PDF, 353 KB

english, 2012

59

Setting the stage for cohesion establishment by the replication fork

Bharti, Sanjay Kumar, Banerjee, Taraswi, Brosh, Robert M.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

60

Editorial [ DNA Repair as a Target for Anti-Cancer Therapy Guest Editor: Robert M. Brosh Jr. ]

Brosh, Jr., Robert

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 16 KB

english, 2008

61

Helicase-inactivating mutations as a basis for dominant negative phenotypes

Wu, Yuliang, Brosh, Jr., Robert M.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.76 MB

english, 2010

62

BRCA-FA Pathway as a Target for Anti-Tumor Drugs

Litman, Rachel, Gupta, Rigu, Brosh, Jr., Robert, Cantor, Sharon

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 121 KB

english, 2008

63

Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress

Monika Aggarwal, Joshua A. Sommers, Robert H. Shoemaker, Robert M. Brosh Jr. and Richard D. Kolodner

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

64

Premature aging syndrome gene WRN genetically interacts with a topoisomerase

Aggarwal, Monika, Brosh, Robert M.

Journal:

Year:

2009

Language:

english

File:

PDF, 792 KB

english, 2009

65

Unique and important consequences of RECQ1 deficiency in mammalian cells

Sharma, Sudha, Brosh, Robert M.

Journal:

Year:

2008

Language:

english

File:

PDF, 755 KB

english, 2008

66

G-quadruplexes and helicases

Mendoza, Oscar, Bourdoncle, Anne, Boulé, Jean-Baptiste, Brosh, Robert M., Mergny, Jean-Louis

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 2.06 MB

english, 2016

67

Biochemical and cell biological assays to identify and characterize DNA helicase inhibitors

Banerjee, Taraswi, Aggarwal, Monika, Sommers, Joshua A., Brosh, Robert M.

Journal:

Year:

2016

Language:

english

File:

PDF, 1020 KB

english, 2016

68

Fanconi Anemia: A DNA repair disorder characterized by accelerated decline of the hematopoietic stem cell compartment and other features of aging

Brosh, Robert M., Bellani, Marina, Liu, Yie, Seidman, Michael M.

Journal:

Ageing Research Reviews

Year:

2016

Language:

english

File:

PDF, 593 KB

english, 2016

69

FANCJ Helicase Operates in the Fanconi Anemia DNA Repair Pathway and the Response to Replicational Stress

Wu, Yuliang, Brosh Jr., Robert

Journal:

Current Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 345 KB

english, 2009

70

Tim/Timeless, a member of the replication fork protection complex, operates with the Warsaw breakage syndrome DNA helicase DDX11 in the same fork recovery pathway

Calì, Federica, Bharti, Sanjay Kumar, Di Perna, Roberta, Brosh, Robert M., Pisani, Francesca M.

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 3.05 MB

english, 2016

71

Fine-Tuning DNA Repair by Protein Acetylation

Bharti, Sanjay Kumar, Brosh, Robert M.

Journal:

Year:

2016

Language:

english

File:

PDF, 806 KB

english, 2016

72

Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase

Khan, Irfan, Crouch, Jack D., Bharti, Sanjay Kumar, Sommers, Joshua A., Carney, Sean M., Yakubovskaya, Elena, Garcia-Diaz, Miguel, Trakselis, Michael A., Brosh, Robert M.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.81 MB

english, 2016

73

Editorial, Ageing Research Reviews

Brosh Tomeny, Robert M.

Journal:

Ageing Research Reviews

Year:

2016

Language:

english

File:

PDF, 135 KB

english, 2016

74

Special Methods collection on DNA helicases

Brosh, Robert M.

Journal:

Year:

2016

Language:

english

File:

PDF, 231 KB

english, 2016

75

CDK1 phosphorylates WRN at collapsed replication forks

Palermo, Valentina, Rinalducci, Sara, Sanchez, Massimo, Grillini, Francesca, Sommers, Joshua A., Brosh, Robert M., Zolla, Lello, Franchitto, Annapaola, Pichierri, Pietro

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 2.08 MB

english, 2016

76

Mechanistic and biological considerations of oxidatively damaged DNA for helicase-dependent pathways of nucleic acid metabolism

Crouch, Jack D., Brosh, Robert M.

Journal:

Free Radical Biology and Medicine

Year:

2016

Language:

english

File:

PDF, 772 KB

english, 2016

77

Detection of G-quadruplex DNA in mammalian cells

Henderson, Alexander, Wu, Yuliang, Huang, Yu Chuan, Chavez, Elizabeth A., Platt, Jesse, Johnson, F. Brad, Brosh, Robert M., Sen, Dipankar, Lansdorp, Peter M.

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 36 KB

english, 2017

78

Mechanistic Insights into How CMG Helicase Facilitates Replication Past DNA Roadblocks

Trakselis, Michael A., Seidman, Michael M., Brosh, Robert M.

Journal:

Year:

2017

Language:

english

File:

PDF, 855 KB

english, 2017

79

RecQ and Fe–S helicases have unique roles in DNA metabolism dictated by their unwinding directionality, substrate specificity, and protein interactions

Estep, Katrina N., Brosh, Robert M.

Journal:

Biochemical Society Transactions

Year:

2017

Language:

english

File:

PDF, 1.69 MB

english, 2017

80

Human RECQ1 Is a DNA Damage Responsive Protein Required for Genotoxic Stress Resistance and Suppression of Sister Chromatid Exchanges

Sharma, Sudha, Brosh, Robert M., Marinus, Martin

Journal:

Year:

2007

Language:

english

File:

PDF, 754 KB

english, 2007

81

Human RECQ1 Interacts with Ku70/80 and Modulates DNA End-Joining of Double-Strand Breaks

Parvathaneni, Swetha, Stortchevoi, Alexei, Sommers, Joshua A., Brosh, Robert M., Sharma, Sudha, Borgmann, Kerstin

Journal:

Year:

2013

Language:

english

File:

PDF, 1.70 MB

english, 2013

82

Impact of Age-Associated Cyclopurine Lesions on DNA Repair Helicases

Khan, Irfan, Suhasini, Avvaru N., Banerjee, Taraswi, Sommers, Joshua A., Kaplan, Daniel L., Kuper, Jochen, Kisker, Caroline, Brosh, Robert M., Korolev, Sergey

Journal:

Year:

2014

Language:

english

File:

PDF, 5.40 MB

english, 2014

83

Getting Ready for the Dance: FANCJ Irons Out DNA Wrinkles

Bharti, Sanjay, Awate, Sanket, Banerjee, Taraswi, Brosh, Robert

Journal:

Year:

2016

Language:

english

File:

PDF, 938 KB

english, 2016

84

New Insights Into DNA Helicases as Druggable Targets for Cancer Therapy

Datta, Arindam, Brosh, Robert M.

Journal:

Frontiers in Molecular Biosciences

Year:

2018

Language:

english

File:

PDF, 2.99 MB

english, 2018

85

BLM’s Balancing Act and the Involvement of FANCJ in DNA Repair

Dhar, Srijita, Brosh, Robert M.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.37 MB

english, 2018

86

Interactive Roles of DNA Helicases and Translocases with the Single-Stranded DNA Binding Protein RPA in Nucleic Acid Metabolism

Awate, Sanket, Brosh, Jr., Robert

Journal:

International Journal of Molecular Sciences

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

87

Fine-tuning of the Replisome: Mcm10 Regulates Fork Progression and Regression

Brosh, Robert M., Trakselis, Michael A.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.20 MB

english, 2019

88

Professor Dr. Mark Mattson’s Special Contributions to Ageing Research and Neuroscience

Brosh, Robert M., Franceschi, Claudio

Journal:

Ageing Research Reviews

Year:

2019

File:

PDF, 690 KB

2019

89

Special Issue on DNA Replication Stress: Summary of Topics Covered

Brosh, Robert M.

Journal:

International Journal of Molecular Sciences

Year:

2019

File:

PDF, 174 KB

2019

90

Call for articles on neglected topics

Franceschi, Claudio, Brosh, Robert M., Fratiglioni, Laura, Salvioli, Stefano, Santoro, Aurelia

Journal:

Ageing Research Reviews

Year:

2019

Language:

english

File:

PDF, 245 KB

english, 2019

91

DNA Helicases and Their Roles in Cancer

Dhar, Srijita, Datta, Arindam, Brosh, Robert M.

Journal:

Year:

2020

File:

PDF, 4.90 MB

2020

92

Synthetic Lethal Interactions of RECQ Helicases

Datta, Arindam, Dhar, Srijita, Awate, Sanket, Brosh, Robert M.

Journal:

Trends in Cancer

Year:

2020

File:

PDF, 1.61 MB

2020

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