Brotchie, Jonathan M.: search on Z-Library

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51

Increased 5-HT2A receptors in the temporal cortex of parkinsonian patients with visual hallucinations

Philippe Huot, Tom H. Johnston, Tayyeba Darr, Lili-Naz Hazrati, Naomi P. Visanji, Donna Pires, Jonathan M. Brotchie, Susan H. Fox

Journal:

Movement Disorders

Year:

2010

Language:

english

File:

PDF, 410 KB

english, 2010

52

Protection of Striatal Neurons by Joint Blockade of D1 and D2 Receptor Subtypes in an in Vitro Model of Cerebral Hypoxia

Sue Davis, Jonathan Brotchie, Ioan Davies

Journal:

Experimental Neurology

Year:

2002

Language:

english

File:

PDF, 194 KB

english, 2002

53

Levodopa-Induced Dyskinesia in Parkinson's Disease ||

Fox, Susan H., Brotchie, Jonathan M.

Year:

2014

Language:

english

File:

PDF, 5.72 MB

english, 2014

54

A critique of available scales and presentation of the non-human primate dyskinesia rating scale

Susan H. Fox, Tom H. Johnston, Qin Li, Jonathan Brotchie, Erwan Bezard

Journal:

Movement Disorders

Year:

2012

Language:

english

File:

PDF, 113 KB

english, 2012

55

5-HT2A receptor levels increase in MPTP-lesioned macaques treated chronically with L-DOPA

Philippe Huot, Tom H. Johnston, Lieke Winkelmolen, Susan H. Fox, Jonathan M. Brotchie

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 1.24 MB

english, 2012

56

Selective loss of bi-directional synaptic plasticity in the direct and indirect striatal output pathways accompanies generation of parkinsonism and l-DOPA induced dyskinesia in mouse models

Thiele, Sherri L., Chen, Betty, Lo, Charlotte, Gertler, Tracey S., Warre, Ruth, Surmeier, James D., Brotchie, Jonathan M., Nash, Joanne E.

Journal:

Neurobiology of Disease

Year:

2014

Language:

english

File:

PDF, 1.68 MB

english, 2014

57

A Common Signaling Pathway for Striatal NMDA and Adenosine A 2a Receptors: Implications for the Treatment of Parkinson's Disease

Nash, Joanne E., Brotchie, Jonathan M.

Journal:

Journal of Neuroscience

Year:

2000

Language:

english

File:

PDF, 216 KB

english, 2000

58

Neural mechanisms underlying peak-dose dyskinesia induced by levodopa and apomorphine are distinct: Evidence from the effects of the alpha2 adrenoceptor antagonist idazoxan

Susan H. Fox, Brian Henry, Micheal P. Hill, David Peggs, Alan R. Crossman, Jonathan M. Brotchie

Journal:

Movement Disorders

Year:

2001

Language:

english

File:

PDF, 102 KB

english, 2001

59

Synaptic recruitment of AMPA glutamate receptor subunits in levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate

Monty A. Silverdale, Christopher Kobylecki, Penelope J. Hallett, Qin Li, Anthone W. Dunah, Paula Ravenscroft, Erwan Bezard, Jonathan M. Brotchie

Journal:

Year:

2010

Language:

english

File:

PDF, 99 KB

english, 2010

60

μ- and δ-Opioid Receptor Antagonists Reduce Levodopa-Induced Dyskinesia in the MPTP-Lesioned Primate Model of Parkinson's Disease

Brian Henry, Susan H. Fox, Alan R. Crossman, Jonathan M. Brotchie

Journal:

Experimental Neurology

Year:

2001

Language:

english

File:

PDF, 75 KB

english, 2001

61

Novel approaches to the symptomatic treatment of parkinsonian syndromes

Brotchie, Jonathan M.

Journal:

Current Opinion in Neurology

Year:

1997

File:

PDF, 465 KB

1997

62

GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson’s Disease

Schneider, Jay S., Aras, Radha, Williams, Courtney K., Koprich, James B., Brotchie, Jonathan M., Singh, Vikrant

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.89 MB

english, 2019

63

NMDA receptors in the basal ganglia

PAULA RAVENSCROFT, JONATHAN BROTCHIE

Journal:

Journal of Anatomy

Year:

2000

Language:

english

File:

PDF, 152 KB

english, 2000

64

5-HT1A receptor stimulation and L-DOPA-induced dyskinesia in Parkinson's disease: Bridging the gap between serotonergic and glutamatergic mechanisms

Philippe Huot, Jonathan M. Brotchie

Journal:

Experimental Neurology

Year:

2011

Language:

english

File:

PDF, 172 KB

english, 2011

65

Modulation of glutamate release by a κ-opioid receptor agonist in rodent and primate striatum

Michael P. Hill, Jonathan M. Brotchie

Journal:

European Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 195 KB

english, 1995

66

Regulation of cortical and striatal 5-HT1A receptors in the MPTP-lesioned macaque

Philippe Huot, Tom H. Johnston, James B. Koprich, Lieke Winkelmolen, Susan H. Fox, Jonathan M. Brotchie

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 1.43 MB

english, 2012

67

Locomotor response to l-DOPA in reserpine-treated rats following central inhibition of aromatic l-amino acid decarboxylase: Further evidence for non-dopaminergic actions of l-DOPA and its metabolites

Amal Alachkar, Jonathan M. Brotchie, Owen T. Jones

Journal:

Neuroscience Research

Year:

2010

Language:

english

File:

PDF, 272 KB

english, 2010

68

Gap junction blockers attenuate beta oscillations and improve forelimb function in hemiparkinsonian rats

Phookan, Sujoy, Sutton, Alexander C., Walling, Ian, Smith, Autumn, O'Connor, Katherine A., Campbell, Joannalee C., Calos, Megan, Yu, Wilson, Pilitsis, Julie G., Brotchie, Jonathan M., Shin, Damian S.

Journal:

Experimental Neurology

Year:

2015

Language:

english

File:

PDF, 2.10 MB

english, 2015

69

5-HT2C receptor binding is increased in the substantia nigra pars reticulata in Parkinson's disease

Susan H. Fox, Jonathan M. Brotchie

Journal:

Movement Disorders

Year:

2000

Language:

english

File:

PDF, 168 KB

english, 2000

70

Translation of nondopaminergic treatments for levodopa-induced dyskinesia from MPTP-lesioned nonhuman primates to phase IIa clinical studies: Keys to success and roads to failure

Susan H. Fox, Anthony E. Lang, Jonathan M. Brotchie

Journal:

Movement Disorders

Year:

2006

Language:

english

File:

PDF, 139 KB

english, 2006

71

Alleviation of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in rat and primate

Jonathan M. Brotchie, Dr. Ian J. Mitchell, Michael A. Sambrook, Alan R. Crossman

Journal:

Movement Disorders

Year:

1991

Language:

english

File:

PDF, 509 KB

english, 1991

72

Effects of adenosine A1, dopamine D1 and metabotropic glutamate 5 receptors-modulating agents on locomotion of the reserpinised rats

Naila Ismayilova, Alan Crossman, Alexei Verkhratsky, Jonathan Brotchie

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 589 KB

english, 2004

73

RGFP109, a histone deacetylase inhibitor attenuates l-DOPA-induced dyskinesia in the MPTP-lesioned marmoset: A proof-of-concept study

Johnston, Tom H., Huot, Philippe, Damude, Sammie, Fox, Susan H., Jones, Steven W., Rusche, James R., Brotchie, Jonathan M.

Journal:

Parkinsonism & Related Disorders

Year:

2013

Language:

english

File:

PDF, 440 KB

english, 2013

74

Pioglitazone may impair L-DOPA anti-parkinsonian efficacy in the MPTP-lesioned macaque: Results of a pilot study

Huot, Philippe, Johnston, Tom H., Fox, Susan H., Brotchie, Jonathan M.

Journal:

Year:

2015

Language:

english

File:

PDF, 544 KB

english, 2015

75

The link between mitochondrial complex I and brain-derived neurotrophic factor in SH-SY5Y cells – The potential of JNX1001 as a therapeutic agent

Kim, Helena K., Mendonça, Karina M., Howson, Patrick A., Brotchie, Jonathan M., Andreazza, Ana C.

Journal:

European Journal of Pharmacology

Year:

2015

Language:

english

File:

PDF, 456 KB

english, 2015

76

DPI-289, a novel mixed delta opioid agonist / mu opioid antagonist (DAMA), has L-DOPA-sparing potential in Parkinson's disease.

Johnston, Tom H., Versi, Eboo, Howson, Patrick A., Ravenscroft, Paula, Fox, Susan H., Hill, Michael P., Reidenberg, Bruce E., Corey, Ronald, Brotchie, Jonathan M.

Journal:

Neuropharmacology

Year:

2017

Language:

english

File:

PDF, 1.29 MB

english, 2017

77

Normethylclozapine potentiates the action of quinpirole in the 6-hydroxydopamine lesioned rat

Susan Fox, Jonathan Brotchie

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 325 KB

english, 1996

78

The effects of fast-off-D2 receptor antagonism on L-DOPA-induced dyskinesia and psychosis in parkinsonian macaques

Koprich, James B., Huot, Philippe, Fox, Susan H., Jarvie, Keith, Lang, Anthony E., Seeman, Philip, Brotchie, Jonathan M.

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

2013

Language:

english

File:

PDF, 582 KB

english, 2013

79

AAV1/2-induced overexpression of A53T-α-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new mouse model for Parkinson’s disease

Ip, Chi Wang, Klaus, Laura-Christin, Karikari, Akua A., Visanji, Naomi P., Brotchie, Jonathan M., Lang, Anthony E., Volkmann, Jens, Koprich, James B.

Journal:

Acta Neuropathologica Communications

Year:

2017

Language:

english

File:

PDF, 9.48 MB

english, 2017

80

Levetiracetam improves choreic levodopa-induced dyskinesia in the MPTP-treated macaque

Erwan Bezard, Michael P. Hill, Alan R. Crossman, Jonathan M. Brotchie, Anne Michel, Renee Grimée, Henrik Klitgaard

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 340 KB

english, 2004

81

Antiparkinsonian Actions of Blockade of NR2B-Containing NMDA Receptors in the Reserpine-Treated Rat

Joanne E. Nash, Michael P. Hill, Jonathan M. Brotchie

Journal:

Experimental Neurology

Year:

1999

Language:

english

File:

PDF, 78 KB

english, 1999

82

Enhancement of the Behavioral Response to Apomorphine Administration Following Repeated Treatment in the 6-Hydroxydopamine-Lesioned Rat Is Temporally Correlated with a Rise in Striatal Preproenkephalin-B, but Not Preproenkephalin-A, Gene Expression

Susan Duty, Jonathan M. Brotchie

Journal:

Experimental Neurology

Year:

1997

Language:

english

File:

PDF, 165 KB

english, 1997

83

The Monoamine Re-Uptake Inhibitor UWA-101 Improves Motor Fluctuations in the MPTP-Lesioned Common Marmoset

Huot, Philippe, Johnston, Tom H., Gandy, Michael N., Reyes, M. Gabriela, Fox, Susan H., Piggott, Matthew J., Brotchie, Jonathan M, Sgambato-Faure, Veronique

Journal:

Year:

2012

Language:

english

File:

PDF, 488 KB

english, 2012

84

Levetiracetam Interferes With the l-Dopa Priming Process in MPTP-Lesioned Drug-Naive Marmosets

Hill, Michael P, Brotchie, Jonathan M, Crossman, Alan R, Bezard, Erwan, Michel, Anne, Grim??e, Renee, Klitgaard, Henrik

Journal:

Clinical Neuropharmacology

Year:

2004

Language:

english

File:

PDF, 200 KB

english, 2004

85

Expression of human A53T alpha-synuclein in the rat substantia nigra using a novel AAV1/2 vector produces a rapidly evolving pathology with protein aggregation, dystrophic neurite architecture and nigrostriatal degeneration with potential to model the pathology of Parkinson's disease

James B Koprich, Tom H Johnston, M Gabriela Reyes, Xuan Sun, Jonathan M Brotchie

Journal:

Molecular Neurodegeneration

Year:

2010

Language:

english

File:

PDF, 2.16 MB

english, 2010

86

PATHOPHYSIOLOGY OF LEVODOPA-INDUCED DYSKINESIA: POTENTIAL FOR NEW THERAPIES

Bezard, Erwan, Brotchie, Jonathan M., Gross, Christian E.

Journal:

Nature Reviews Neuroscience

Year:

2001

Language:

english

File:

PDF, 901 KB

english, 2001

87

Differential effects of endocannabinoids on [3H]-GABA uptake in the rat globus pallidus

Katerina Venderova, Timothy M. Brown, Jonathan M. Brotchie

Journal:

Experimental Neurology

Year:

2005

Language:

english

File:

PDF, 98 KB

english, 2005

88

α2-Adrenoceptor-mediated modulation of the release of GABA and noradrenaline in the rat substantia nigra pars reticulata

Amal Alachkar, Jonathan Brotchie, Owen T. Jones

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 282 KB

english, 2006

89

Nondopaminergic mechanisms in levodopa-induced dyskinesia

Jonathan M. Brotchie

Journal:

Movement Disorders

Year:

2005

Language:

english

File:

PDF, 119 KB

english, 2005

90

Beneficial effects of trehalose on striatal dopaminergic deficits in rodent and primate models of synucleinopathy in Parkinson's disease.

Howson, Patrick A., Johnston, Tom H., Ravenscroft, Paula, Hill, Michael P, Su, Jin, Brotchie, Jonathan M., Koprich, James B.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2019

File:

PDF, 617 KB

2019

91

Novel antiepileptic drug levetiracetam decreases dyskinesia elicited by L-dopa and ropinirole in the MPTP-lesioned marmoset

Michael P. Hill, Erwan Bezard, Steven G. McGuire, Alan R. Crossman, Jonathan M. Brotchie, Ann Michel, Renee Grimée, Henrik Klitgaard

Journal:

Movement Disorders

Year:

2003

Language:

english

File:

PDF, 82 KB

english, 2003

92

Pros and cons of a prion-like pathogenesis in Parkinson's disease

Ruediger Hilker, Jonathan M Brotchie, Joab Chapman

Journal:

Year:

2011

Language:

english

File:

PDF, 212 KB

english, 2011

93

l-DOPA pharmacokinetics in the MPTP-lesioned macaque model of Parkinson's disease

Huot, Philippe, Johnston, Tom H., Koprich, James B., Fox, Susan H., Brotchie, Jonathan M.

Journal:

Neuropharmacology

Year:

2012

Language:

english

File:

PDF, 323 KB

english, 2012

94

Neuropsychiatric Behaviors in the MPTP Marmoset Model of Parkinson’s Disease

Fox, Susan H., Visanji, Naomi, Reyes, Gaby, Huot, Philippe, Gomez-Ramirez, Jordi, Johnston, Tom, Brotchie, Jonathan M.

Journal:

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

Year:

2010

File:

PDF, 300 KB

2010

95

Levodopa-induced dyskinesias

Giovanni Fabbrini, Jonathan M. Brotchie, Francisco Grandas, Masahiro Nomoto, Christopher G. Goetz

Journal:

Movement Disorders

Year:

2007

Language:

english

File:

PDF, 109 KB

english, 2007

96

Novel pharmacological targets for the treatment of Parkinson's disease

Schapira, Anthony H. V., Bezard, Erwan, Brotchie, Jonathan, Calon, Frédéric, Collingridge, Graham L., Ferger, Borris, Hengerer, Bastian, Hirsch, Etienne, Jenner, Peter, Novère, Nicolas Le

Journal:

Nature Reviews Drug Discovery

Year:

2006

Language:

english

File:

PDF, 655 KB

english, 2006

97

A simple rodent assay for the in vivo identification of agents with potential to reduce levodopa-induced dyskinesia in Parkinson's disease

Tom H. Johnston, Joohyung Lee, Jordi Gomez-Ramirez, Susan H. Fox, Jonathan M. Brotchie

Journal:

Experimental Neurology

Year:

2005

Language:

english

File:

PDF, 685 KB

english, 2005

98

Response to Obeso et al.: Presymptomatic compensation in Parkinson's disease is not dopamine-mediated

Erwan Bezard, Christian E Gross, Jonathan M Brotchie

Journal:

Trends in Neurosciences

Year:

2004

Language:

english

File:

PDF, 55 KB

english, 2004

99

Ionotropic glutamate receptors and nitric oxide synthesis in the rat striatum

East, Stephen J., Parry-Jones, Adrian, Brotchie, Jonathan M.

Journal:

Year:

1996

Language:

english

File:

PDF, 86 KB

english, 1996

100

[Progress in Brain Research] Chemical Signalling in the Basal Ganglia Volume 99 || Chapter 8 Chemical signalling in the globus pallidus in parkinsonism

Brotchie, Jonathan

Year:

1993

Language:

english

File:

PDF, 1.35 MB

english, 1993

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