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51

Evidence That Phosphatidylinositol 3-Kinase- and Mitogen-activated Protein Kinase Kinase-4/c-Jun NH2-terminal Kinase-dependent Pathways Cooperate to Maintain Lung Cancer Cell Survival

Lee, H.-Y., Srinivas, H., Xia, D., Lu, Y., Superty, R., LaPushin, R., Gomez-Manzano, C., Gal, A. M., Walsh, G. L., Force, T., Ueki, K., Mills, G. B., Kurie, J. M.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 1015 KB

english, 2003

52

Genetically modified adenoviruses against gliomas: From bench to bedside

Gomez-Manzano, C., Yung, W.K. A., Alemany, R., Fueyo, J.

Journal:

Year:

2004

Language:

english

File:

PDF, 332 KB

english, 2004

53

[Handbook of Clinical Neurology] Neuro-Oncology. Vol 104 HCN Series Volume 104 || Gene therapy

Gomez-Manzano, Candelaria

Year:

2012

Language:

english

File:

PDF, 423 KB

english, 2012

54

Macrophage Ablation Reduces M2-Like Populations and Jeopardizes Tumor Growth in a MAFIA-Based Glioma Model

Gabrusiewicz, Konrad, Hossain, Mohammad B., Cortes-Santiago, Nahir, Fan, Xuejun, Kaminska, Bozena, Marini, Frank C., Fueyo, Juan, Gomez-Manzano, Candelaria

Journal:

Year:

2015

Language:

english

File:

PDF, 2.37 MB

english, 2015

55

Adenovirus’s last trick: You say lysis, we say autophagy

Jiang, Hong, White, Erin J., Gomez-Manzano, Candelaria, Fueyo-Margareto, Juan

Journal:

Year:

2008

Language:

english

File:

PDF, 328 KB

english, 2008

56

Gene therapy for gliomas: p53 and E2F-1 proteins and the target of apoptosis.

Gomez-Manzano, C, Fueyo, J, Alameda, F, Kyritsis, A P, Yung, W K

Journal:

International Journal of Molecular Medicine

Year:

1999

Language:

english

File:

PDF, 1.51 MB

english, 1999

57

Adenovirus-mediated p16 transfer to glioma cells induces G1 arrest and protects from paclitaxel and topotecan: implications for therapy.

Fueyo, J, Gomez-Manzano, C, Puduvalli, V K, Martin-Duque, P, Perez-Soler, R, Levin, V A, Yung, W K, Kyritsis, A P

Journal:

International Journal of Oncology

Year:

1998

Language:

english

File:

PDF, 1.41 MB

english, 1998

58

Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU

Gomez-Manzano, Candelaria, Lemoine, Michael, Hu, Min, He, Ju, Mitlianga, Paraskevi, Liu, Ta-Jen, Yung, Alfred, Fueyo, Juan, Groves, Morris

Journal:

International Journal of Oncology

Year:

2001

Language:

english

File:

PDF, 1.81 MB

english, 2001

59

Co-expression of E2F-2 enhances the p53 anti-cancer effect in human glioma cells

Mitlianga, P., Kyritsis, A., Gomez-Manzano, C., Lemoine, M., Hu, M., Liu, T.-J., Yung, W., Fueyo, J.

Journal:

International Journal of Oncology

Year:

2001

Language:

english

File:

PDF, 1.35 MB

english, 2001

60

Overexpression of E2F-1 leads to bax-independent cell death in human glioma cells

Mitlianga, Paraskevi, Gomez-Manzano, Candelaria, Kyritsis, Athanassios, Fueyo, Juan

Journal:

International Journal of Oncology

Year:

2002

Language:

english

File:

PDF, 1.55 MB

english, 2002

61

Adenovirus, autophagy and lysis: ecstasies and agonies

Balvers, Rutger, Jiang, Hong, Piya, Sujan, Gomez-Manzano, Candelaria, Fueyo, Juan

Journal:

Future Virology

Year:

2011

Language:

english

File:

PDF, 293 KB

english, 2011

62

Delta-24-RGD Induces Cytotoxicity of Glioblastoma Spheroids in Three Dimensional PEG Microwells

Avci, Naze G., Fan, Yantao, Dragomir, Andrei, Akay, Yasemin M., Gomez-Manzano, Candelaria, Fueyo-Margareto, Juan, Akay, Metin

Journal:

IEEE Transactions on NanoBioscience

Year:

2015

Language:

english

File:

PDF, 1.22 MB

english, 2015

63

Interspecies adenovirus fiber shows "evolutionary" advantage for oncolytic therapy of gliomas

Gomez-Manzano, Candelaria, Alonso, Marta, Jiang, Hong, Fueyo, Juan

Journal:

Cancer Biology & Therapy

Year:

2008

Language:

english

File:

PDF, 802 KB

english, 2008

64

E2F1 and Telomerase: Alliance in the Dark Side

Alonso, Marta M., Fueyo-Margareto, Juan, Yung, W.K. Alfred, Gomez-Manzano, Candelaria

Journal:

Year:

2006

Language:

english

File:

PDF, 323 KB

english, 2006

65

RB-E2F1

Jiang, Hong, Martin, Vanesa, Alonso, Marta, Gomez-Manzano, Candelaria, Fueyo-Margareto, Juan

Journal:

Year:

2010

Language:

english

File:

PDF, 679 KB

english, 2010

66

ET-66 * ER-STRESS INDUCING DRUGS SENSITIZES GBM TO TEMOZOLOMIDE THROUGH DOWNREGULATION OF MGMT AND INDUCTION OF REGULATED NECROSIS

Xipell, E., Martinez-Velez, N., Vera-Cano, B., Idoate, M. A., Garzon, A. G., Acanda, A. M., Fueyo, J., Gomez-Manzano, C., Alonso, M. M.

Journal:

Year:

2014

Language:

english

File:

PDF, 24 KB

english, 2014

67

PRESENCE OF A DISTINCTIVE MYELOID POPULATION IS ASSOCIATED WITH THE INVASIVE TUMOR PHENOTYPE OBSERVED AFTER ANTI-ANGIOGENESIS THERAPIES

Gomez-Manzano, C., Gabrusiewicz, K., Cortes-Santiago, N., Hossain, M. B., Conrad, C., Fuller, G., Aldape, K., Lang, F., Gilbert, M., Alfred Yung, W. K., Fueyo, J.

Journal:

Year:

2014

Language:

english

File:

PDF, 28 KB

english, 2014

68

IM-04 * DELTA-24-RDG AS AN ALTERNATIVE THERAPEUTIC TOOL FOR pHGG/DIPG

Martinez-Velez, N., Xipell, E., Jiang, H., Gomez-Manzano, C., Fueyo, J., Junier, M.-P., Chneiweiss, H., El Habr, E., Monje, M., Becher, O., Alonso, M. M.

Journal:

Year:

2015

Language:

english

File:

PDF, 28 KB

english, 2015

69

IT-15 * DELTA-24-RGDOX: TARGETING CO-STIMULATORY IMMUNE CHECKPOINT PROTEINS WITH ONCOLYTIC ADENOVIRUSES

Jiang, H., Lang, F., Fan, X., Gumin, J., Bover, L., Clise-Dwyer, K., Toniatti, C., Ruisaard, K., Conrad, C., Vence, L., Gomez-Manzano, C., Fueyo, J.

Journal:

Year:

2014

Language:

english

File:

PDF, 27 KB

english, 2014

70

ME-05 * COUNTERATTACKING THE FORCE BEHIND GLIOMA INVASION

Cortes-Santiago, N., Hossain, M. B., Gabrusiewicz, K., Fan, X., Jiang, H., Shifat, R., Alonso, M. M., Fueyo, J., Gomez-Manzano, C.

Journal:

Year:

2014

Language:

english

File:

PDF, 24 KB

english, 2014

71

IMPS-09COMBINATION OF DELTA-24-RGDOX AND ANTI-PDL1 ANTIBODIES INDUCES ANTI-TUMOR EFFECT AND ANTI-GLIOMA IMMUNE MEMORY

Jiang, Hong, Gomez-Manzano, Candelaria, Lang, Frederick, Tufaro, Frank, Yung, W.K. Alfred, Sawaya, Raymond, Fueyo, Juan

Journal:

Year:

2015

Language:

english

File:

PDF, 28 KB

english, 2015

72

Encountering and Advancing Through Antiangiogenesis Therapy for Gliomas

Martin, Vanesa, Liu, Dan, Gomez-Manzano, Candelaria

Journal:

Current Pharmaceutical Design

Year:

2009

Language:

english

File:

PDF, 318 KB

english, 2009

73

Advances in Translational Research in Neuro-oncology

Fueyo, Juan, Gomez-Manzano, Candelaria, Yung, W. K. Alfred

Journal:

Archives of Neurology

Year:

2011

Language:

english

File:

PDF, 477 KB

english, 2011

74

Tumor-associated stromal cells as key contributors to the tumor microenvironment

Bussard, Karen M., Mutkus, Lysette, Stumpf, Kristina, Gomez-Manzano, Candelaria, Marini, Frank C.

Journal:

Breast Cancer Research

Year:

2016

Language:

english

File:

PDF, 705 KB

english, 2016

75

Targeting in Gene Therapy for Gliomas

Fueyo, Juan, Gomez-Manzano, Candelaria, Yung, W. K. Alfred, Kyritsis, Athanassios P.

Journal:

Archives of Neurology

Year:

1999

Language:

english

File:

PDF, 141 KB

english, 1999

76

Phase I Trial of DNX-2401 for Diffuse Intrinsic Pontine Glioma Newly Diagnosed in Pediatric Patients

Tejada, Sonia, Alonso, Marta, Patiño, Ana, Fueyo, Juan, Gomez-Manzano, Candelaria, Diez-Valle, Ricardo

Journal:

Year:

2017

Language:

english

File:

PDF, 308 KB

english, 2017

77

PDTM-12. THE ONCOLYTIC ADENOVIRUS DELTA-24-RGD MEDIATES AN EFFICIENT ANTITUMOR RESPONSE IN VIVO IN SUPRATENTORIAL PRIMITIVE NEUROECTODERMAL TUMORS

Garcia-Moure, Marc, Martínez-Vélez, Naiara, González-Huarriz, Marisol, Puigdelloses, Monsterrat, Idoate, Miguel Angel, Valle, Ricardo Diez, Tejada, Sonia, Gomez-manzano, Candelaria, Fueyo, Juan, Patiñ

Journal:

Year:

2017

Language:

english

File:

PDF, 50 KB

english, 2017

78

Linking inflammation and cancer: the unexpected SYK world

Fueyo, Juan, Alonso, Marta M, Parker Kerrigan, Brittany C, Gomez-Manzano, Candelaria

Journal:

Year:

2018

Language:

english

File:

PDF, 327 KB

english, 2018

79

Potentiation of anti-glioma immunity induced by oncolytic adenovirus Delta-24-RGD through viral expression of immune co-stimulator OX40 ligand

Jiang, Hong, Dwyer, Karen, Bover, Laura, Lang, Frederick, Gomez-Manzano, Candelaria, Fueyo, Juan

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2015

Language:

english

File:

PDF, 210 KB

english, 2015

80

ATIM-08. IMMUNOMARKERS IN THE DNX-2401 (DELTA-24-RGD) ONCOLYTIC VIRUS PHASE I CLINICAL TRIAL

Fueyo, Juan, Gomez-Manzano, Candelaria, Villalobos, Paloma, Rodriguez-Canales, Jaime, Wistuba, Ignacio, Hess, Kenneth R, Alonso, Marta M, Tejada, Sonia, Valle, Ricardo Diez, Ewald, Brett, Tufaro, Fran

Journal:

Year:

2017

Language:

english

File:

PDF, 51 KB

english, 2017

81

Critical Role of Autophagy in the Processing of Adenovirus Capsid-Incorporated Cancer-Specific Antigens

Klein, Sarah R., Jiang, Hong, Hossain, Mohammad B., Fan, Xuejun, Gumin, Joy, Dong, Andrew, Alonso, Marta M., Gomez-Manzano, Candelaria, Fueyo, Juan, Castro, Maria G

Journal:

Year:

2016

Language:

english

File:

PDF, 1.12 MB

english, 2016

82

DIPG-17. ONCOLYTIC VIRUS FOR pHGG AND DIPGs: FROM THE BENCH TO THE BEDSIDE

Tejada, Sonia, Martinez-Velez, Naiara, Varela, Maider, Dominguez, Pablo, Fueyo, Juan, Gomez-Manzano, Candelaria, Aristu, Javier, Diez, Ricardo, Alonso, Marta

Journal:

Year:

2018

Language:

english

File:

PDF, 54 KB

english, 2018

83

DNX-2401, an Oncolytic Virus, for the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Gliomas: A Case Report

Tejada, Sonia, Díez-Valle, Ricardo, Domínguez, Pablo D., Patiño-García, Ana, González-Huarriz, Marisol, Fueyo, Juan, Gomez-Manzano, Cande, Idoate, Miguel Angel, Peterkin, Joanna, Alonso, Marta M.

Journal:

Frontiers in Oncology

Year:

2018

Language:

english

File:

PDF, 941 KB

english, 2018

84

Oncolytic Viruses as Therapeutic Tools for Pediatric Brain Tumors

Varela-Guruceaga, Maider, Tejada-Solís, Sonia, García-Moure, Marc, Fueyo, Juan, Gomez-Manzano, Candelaria, Patiño-García, Ana, Alonso, Marta

Journal:

Year:

2018

Language:

english

File:

PDF, 842 KB

english, 2018

85

GENE-19. TIE2-MEDIATED EPIGENETIC MODIFICATIONS REGULATE RADIORESISTANCE OF GLIOBLASTOMA

Hossain, Mohammad, Shifat, Rehnuma, Rivera-Molina, Yisel, Puerta-Martinez, Francisco, Jiang, Hong, Kim, Debora, Johnson, David, Bedford, Mark, Sulman, Erik, Lang, Frederick, Fueyo, Juan, Gomez-Manzano

Journal:

Year:

2017

Language:

english

File:

PDF, 81 KB

english, 2017

86

HG-51DELTA-24-RDG IN COMBINATION WITH RADIOTHERAPY FOR DIPG: OPENING NEW THERAPEUTIC AVENUES

Martinez-Velez, Naiara, Marigil, Miguel, Dominguez, Pablo, Aristu, Javier, Fueyo, Juan, Gomez-Manzano, Cande, Junier, Marie Piere, Chneiweiss, Herve, El-Habr, Elias A., Diaz-Valle, Ricardo, Tejada, So

Journal:

Year:

2016

Language:

english

File:

PDF, 58 KB

english, 2016

87

Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma

Lang, Frederick F., Conrad, Charles, Gomez-Manzano, Candelaria, Yung, W.K. Alfred, Sawaya, Raymond, Weinberg, Jeffrey S., Prabhu, Sujit S., Rao, Ganesh, Fuller, Gregory N., Aldape, Kenneth D., Gumin,

Journal:

Journal of Clinical Oncology

Year:

2018

File:

PDF, 1.81 MB

2018

88

DIPG-04. TRANSLATION OF DNX-2401 FROM THE BENCH TO THE CLINIC FOR PEDIATRIC HIGH GRADE GLIOMAS INCLUDING DIFFUSE INTRINSIC PONTINE GLIOMAS

Martinez-Velez, Naiara, Garcia-Moure, Marc, Laspidea, Virginia, Becher, Oren, Fueyo, Juan, Gomez-Manzano, Candelaria, Patiño, Ana, Diez-Valle, Ricardo, Tejada-Solis, Sonia, Alonso, Marta

Journal:

Year:

2019

Language:

english

File:

PDF, 129 KB

english, 2019

89

GITRL-armed Delta-24-RGD oncolytic adenovirus prolongs survival and induces anti-glioma immune memory

Rivera-Molina, Yisel, Jiang, Hong, Fueyo, Juan, Nguyen, Teresa, Shin, Dong Ho, Youssef, Gilbert, Fan, Xuejun, Gumin, Joy, Alonso, Marta M, Phadnis, Sheetal, Lang, Frederick F, Gomez-Manzano, Candelari

Journal:

Neuro-Oncology Advances

Year:

2019

Language:

english

File:

PDF, 881 KB

english, 2019

90

Antitumor immune response during glioma virotherapy

Youssef, Gilbert C, Gomez-Manzano, Candelaria, Sawaya, Raymond, Fueyo, Juan

Journal:

Year:

2019

Language:

english

File:

PDF, 154 KB

english, 2019

91

EXTH-30. IN SITU AUTOVACCINATION MEDIATED BY ONCOLYTIC ADENOVIRUS DELTA-24-RGDOX INDUCES EFFICACIOUS IMMUNITY AGAINST METASTATIC MELANOMA

Jiang, Hong, Nguyen, Teresa, Ho Shi, Dong, Fan, Xuejun, Gumin, Joy, Bernatchez, Chantale, Lang, Frederick, Gomez-Manzano, Candelaria, Fueyo, Juan

Journal:

Year:

2018

Language:

english

File:

PDF, 80 KB

english, 2018

92

EXTH-30. IN SITU AUTOVACCINATION MEDIATED BY ONCOLYTIC ADENOVIRUS DELTA-24-RGDOX INDUCES EFFICACIOUS IMMUNITY AGAINST METASTATIC MELANOMA

Jiang, Hong, Nguyen, Teresa, Ho Shi, Dong, Fan, Xuejun, Gumin, Joy, Bernatchez, Chantale, Lang, Frederick, Gomez-Manzano, Candelaria, Fueyo, Juan

Journal:

Year:

2018

File:

PDF, 80 KB

2018

93

PDCT-18 (LTBK-03). PHASE I CLINICAL TRIAL WITH ONCOLYTIC VIRUS DNX-2401 FOR DIPGS

Iñigo-Marco, Ignacio, Díez-Valle, Ricardo, Garcia-Moure, Marc, Patiño-García, Ana, González Huarriz, Marisol, Jones, Chris, Gomez-Manzano, Candelaria, Fueyo, Juan, Alonso, Marta M, Tejada, Sonia

Journal:

Year:

2019

Language:

english

File:

PDF, 156 KB

english, 2019

94

IMMU-14. ONCOLYTIC VIRUS EXPRESSING A POSITIVE IMMUNE CHECKPOINT MODULATOR AS A THERAPEUTIC APPROACH FOR DIPG

Laspidea, Virginia, Puigdelloses, Montse, IÃ±igo-Marco, Ignacio, Garcia-Moure, Marc, Ausejo, Iker, Gallego, Jaime, Fueyo, Juan, Gomez-Manzano, Candelaria, Alonso, Marta M

Journal:

Year:

2019

File:

PDF, 88 KB

2019

95

EXTH-27. ACTIVATING THE IMMUNITY WITHIN THE TUMOR USING VIROIMMUNOTHERAPY: DELTA-24-RGD ONCOLYTIC ADENOVIRUS ARMED WITH THE IMMUNOPOSITIVE REGULATOR GITRL

Rivera-Molina, Yisel, Fueyo, Juan, Jiang, Hong, Nguyen, Teresa, Ho Shin, Dong, Youssef, Gilbert, Fan, Xuejun, Gumin, Joy, Alonso, Marta M, Phadnis, Sheetal, Lang, Frederick, Gomez-Manzano, Candelaria

Journal:

Year:

2019

File:

PDF, 88 KB

2019

96

PDTM-23. DELTA-24-RGD ONCOLYTIC ADENOVIRUS MEDIATES ANTI-TUMOR EFFECT IN LOCALIZED AND DISSEMINATED AT/RT MURINE MODELS

Garcia-Moure, Marc, GonzÃ¡lez Huarriz, Marisol, Laspidea, Virginia, MarrodÃ¡n, LucÃa, Gomez-Manzano, Candelaria, Fueyo, Juan, PatiÃ±o-GarcÃa, Ana, Alonso, Marta M

Journal:

Year:

2019

File:

PDF, 92 KB

2019

97

EXTH-11. TREATMENT WITH DELTA-24-RGDOX OF SUBCUTANEOUS TUMORS RESULTS IN ABSCOPAL EFFECT ERADICATING INTRACRANIAL MELANOMAS

Jiang, Hong, Ho Shin, Dong, Nguyen, Teresa, Alonso, Marta M, Lang, Frederick, Gomez-Manzano, Candelaria, Fueyo, Juan

Journal:

Year:

2019

File:

PDF, 90 KB

2019