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51

Design, Radiosynthesis, and Biodistribution of a New Potent and Selective Ligand for in Vivo Imaging of the Adenosine A 2A Receptor System Using Positron Emission Tomography

Todde, Sergio, Moresco, Rosa Maria, Simonelli, Pasquale, Baraldi, Pier Giovanni, Cacciari, Barbara, Spalluto, Giampiero, Varani, Katia, Monopoli, Angela, Matarrese, Mario, Carpinelli, Assunta, Magni,

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 74 KB

english, 2000

52

Design, Synthesis, and Biological Evaluation of a Second Generation of Pyrazolo[4,3- e ]-1,2,4-triazolo[1,5- c ]pyrimidines as Potent and Selective A 2A Adenosine Receptor Antagonists

Baraldi, Pier Giovanni, Cacciari, Barbara, Spalluto, Giampiero, Bergonzoni, Manuela, Dionisotti, Silvio, Ongini, Ennio, Varani, Katia, Borea, P. A.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 159 KB

english, 1998

53

Exploring Potency and Selectivity Receptor Antagonist Profiles Using a Multilabel Classification Approach: The Human Adenosine Receptors as a Key Study

Michielan, Lisa, Stephanie, Federico, Terfloth, Lothar, Hristozov, Dimitar, Cacciari, Barbara, Klotz, Karl-Norbert, Spalluto, Giampiero, Gasteiger, Johann, Moro, Stefano

Journal:

Journal of Chemical Information and Modeling

Year:

2009

Language:

english

File:

PDF, 863 KB

english, 2009

54

Linear and Nonlinear 3D-QSAR Approaches in Tandem with Ligand-Based Homology Modeling as a Computational Strategy To Depict the Pyrazolo-Triazolo-Pyrimidine Antagonists Binding Site of the Human Adenosine A 2A Receptor

Michielan, Lisa, Bacilieri, Magdalena, Schiesaro, Andrea, Bolcato, Chiara, Pastorin, Giorgia, Spalluto, Giampiero, Cacciari, Barbara, Klotz, Karl Norbet, Kaseda, Chosei, Moro, Stefano

Journal:

Journal of Chemical Information and Modeling

Year:

2008

Language:

english

File:

PDF, 786 KB

english, 2008

55

Pyrazolo[4,3- e ]-1,2,4-triazolo[1,5- c ]pyrimidine Derivatives: Potent and Selective A 2A Adenosine Antagonists

Baraldi, Pier Giovanni, Cacciari, Barbara, Spalluto, Giampiero, Pineda de las Infantas y Villatoro, Maria José, Zocchi, Cristina, Dionisotti, Silvio, Ongini, Ennio

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 343 KB

english, 1996

56

To Break the Embarrassment

Nesi, Barbara, Levorato, Maria Chiara, Roch, Maja, Cacciari, Cristina

Journal:

European Psychologist

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

57

Synthesis and Biological Studies of a New Series of 5-Heteroarylcarbamoylaminopyrazolo[4,3- e ]1,2,4-triazolo[1,5- c ]pyrimidines as Human A 3 Adenosine Receptor Antagonists. Influence of the Heteroaryl Substituent on Binding Affinity and Molecular Modeling Investigations

Pastorin, Giorgia, Da Ros, Tatiana, Bolcato, Chiara, Montopoli, Christian, Moro, Stefano, Cacciari, Barbara, Baraldi, Pier Giovanni, Varani, Katia, Borea, Pier Andrea, Spalluto, Giampiero

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 479 KB

english, 2006

58

Synthesis and Antitumor Activity of a New Class of Pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone Analogs of Pyrrolo[1,4][2,1-c]benzodiazepines

Baraldi, Pier Giovanni, Leoni, Alberto, Cacciari, Barbara, Manfredini, Stefano, Simoni, Daniele, Bergomi, Marzia, Menta, Ernesto, Spinelli, Silvano

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.25 MB

english, 1994

59

Carbon Nanotube Substrates Boost Neuronal Electrical Signaling

Lovat, Viviana, Pantarotto, Davide, Lagostena, Laura, Cacciari, Barbara, Grandolfo, Micaela, Righi, Massimo, Spalluto, Giampiero, Prato, Maurizio, Ballerini, Laura

Journal:

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

60

Revisiting a Receptor-Based Pharmacophore Hypothesis for Human A 2A Adenosine Receptor Antagonists

Bacilieri, Magdalena, Ciancetta, Antonella, Paoletta, Silvia, Federico, Stephanie, Cosconati, Sandro, Cacciari, Barbara, Taliani, Sabrina, Da Settimo, Federico, Novellino, Ettore, Klotz, Karl Norbert,

Journal:

Journal of Chemical Information and Modeling

Year:

2013

Language:

english

File:

PDF, 2.43 MB

english, 2013

61

Synthesis and Biological Activity of a New Series of N 6 -Arylcarbamoyl, 2-(Ar)alkynyl- N 6 -arylcarbamoyl, and N 6 -Carboxamido Derivatives of Adenosine-5‘- N -ethyluronamide as A 1 and A 3 Adenosine Receptor Agonists

Baraldi, Pier Giovanni, Cacciari, Barbara, Pineda de Las Infantas, Maria José, Romagnoli, Romeo, Spalluto, Giampiero, Volpini, Rosaria, Costanzi, Stefano, Vittori, Sauro, Cristalli, Gloria, Melman, Ne

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 240 KB

english, 1998

62

Facile and Versatile Route to the Synthesis of Fused 2‐Pyridones: Useful Intermediates for Polycyclic Sytems

Spalluto, Giampiero, Cacciari, Barbara

Journal:

Synthetic Communications

Year:

2006

Language:

english

File:

PDF, 99 KB

english, 2006

63

7-Substituted 5-Amino-2-(2-furyl)pyrazolo[4,3- e ]-1,2,4-triazolo[1,5- c ]pyrimidines as A 2A Adenosine Receptor Antagonists: A Study on the Importance of Modifications at the Side Chain on the Activity and Solubility

Baraldi, Pier Giovanni, Cacciari, Barbara, Romagnoli, Romeo, Spalluto, Giampiero, Monopoli, Angela, Ongini, Ennio, Varani, Katia, Borea, Pier Andrea

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 164 KB

english, 2002

64

8-(2-Furyl)adenine derivatives as A2A adenosine receptor ligands

Dal Ben, Diego, Buccioni, Michela, Lambertucci, Catia, Thomas, Ajiroghene, Klotz, Karl-Norbert, Federico, Stephanie, Cacciari, Barbara, Spalluto, Giampiero, Volpini, Rosaria

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 2.05 MB

english, 2013

65

Pyrazolo[4,3- e ]-1,2,4-triazolo[1,5- c ]pyrimidine Derivatives as Highly Potent and Selective Human A 3 Adenosine Receptor Antagonists

Baraldi, Pier Giovanni, Cacciari, Barbara, Romagnoli, Romeo, Spalluto, Giampiero, Klotz, Karl-Norbert, Leung, Edward, Varani, Katia, Gessi, Stefania, Merighi, Stefania, Borea, Pier Andrea

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 74 KB

english, 1999

66

Pyrazolo[4,3- e ]-1,2,4-triazolo[1,5- c ]pyrimidine Derivatives as Adenosine Receptor Antagonists. Influence of the N5 Substituent on the Affinity at the Human A 3 and A 2B Adenosine Receptor Subtypes: A Molecular Modeling Investigation

Pastorin, Giorgia, Da Ros, Tatiana, Spalluto, Giampiero, Deflorian, Francesca, Moro, Stefano, Cacciari, Barbara, Baraldi, Pier Giovanni, Gessi, Stefania, Varani, Katia, Borea, Pier Andrea

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 903 KB

english, 2003

67

Unusual Ring-Opening Reaction of 6,7-Dihydrothieno[3,2-d]pyrimidine-2,4-dione Derivatives Leading to 5-(Alkylthio)-6-vinyluracils

Baraldi, Pier Giovanni, Cacciari, Barbara, Manfredini, Stefano, Pollini, Gian Piero, Simoni, Daniele, Spalluto, Giampiero, Zanirato, Vinicio

Journal:

Journal of Organic Chemistry

Year:

1995

Language:

english

File:

PDF, 350 KB

english, 1995

68

Novel N 6 -(Substituted-phenylcarbamoyl)adenosine-5‘-uronamides as Potent Agonists for A 3 Adenosine Receptors

Baraldi, Pier Giovanni, Cacciari, Barbara, Spalluto, Giampiero, Ji, Xiao-duo, Olah, Mark E., Stiles, Gary, Dionisotti, Silvio, Zocchi, Cristina, Ongini, Ennio, Jacobson, Kenneth A.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 146 KB

english, 1996

69

Scaffold Decoration at Positions 5 and 8 of 1,2,4-Triazolo[1,5- c ]Pyrimidines to Explore the Antagonist Profiling on Adenosine Receptors: A Preliminary Structure–Activity Relationship Study

Federico, Stephanie, Ciancetta, Antonella, Porta, Nicola, Redenti, Sara, Pastorin, Giorgia, Cacciari, Barbara, Klotz, Karl Norbert, Moro, Stefano, Spalluto, Giampiero

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 3.59 MB

english, 2014

70

Synthesis and Properties of Substituted CBI Analogs of CC-1065 and the Duocarmycins Incorporating the 7-Methoxy-1,2,9,9a-tetrahydrocyclopropa[ c ]benz[ e ]indol-4-one (MCBI) Alkylation Subunit: Magnitude of Electronic Effects on the Functional Reactivity

Boger, Dale L., McKie, Jeffrey A., Cai, Hui, Cacciari, Barbara, Baraldi, P. G.

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 1.07 MB

english, 1996

71

Synthesis, in Vitro Antiproliferative Activity, and DNA-Binding Properties of Hybrid Molecules Containing Pyrrolo[2,1- c ][1,4]benzodiazepine and Minor-Groove-Binding Oligopyrrole Carriers

Baraldi, Pier Giovanni, Balboni, Gianfranco, Cacciari, Barbara, Guiotto, Andrea, Manfredini, Stefano, Romagnoli, Romeo, Spalluto, Giampiero, Thurston, David E., Howard, Philip W., Bianchi, Nicoletta,

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 281 KB

english, 1999

72

Pyrazolo[4,3- e ]1,2,4-triazolo[1,5- c ]pyrimidine Derivatives as Highly Potent and Selective Human A 3 Adenosine Receptor Antagonists: Influence of the Chain at the N 8 Pyrazole Nitrogen

Baraldi, Pier Giovanni, Cacciari, Barbara, Romagnoli, Romeo, Spalluto, Giampiero, Moro, Stefano, Klotz, Karl-Norbert, Leung, Edward, Varani, Katia, Gessi, Stefania, Merighi, Stefania, Borea, Pier Andr

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 200 KB

english, 2000

73

Synthesis, Biological Properties, and Molecular Modeling Investigation of the First Potent, Selective, and Water-Soluble Human A 3 Adenosine Receptor Antagonist

Maconi, Anna, Pastorin, Giorgia, Da Ros, Tatiana, Spalluto, Giampiero, Gao, Zhan-guo, Jacobson, Kenneth A., Baraldi, Pier Giovanni, Cacciari, Barbara, Varani, Katia, Moro, Stefano, Borea, Pier Andrea

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 142 KB

english, 2002

74

Demystifying the three dimensional structure of G protein-coupled receptors (GPCRs) with the aid of molecular modeling

Moro, Stefano, Deflorian, Francesca, Spalluto, Giampiero, Pastorin, Giorgia, Cacciari, Barbara, Kim, Soo-Kyung, Jacobson, Kenneth A.

Journal:

Chemical Communications

Year:

2003

Language:

english

File:

PDF, 1.09 MB

english, 2003

75

Pyrazolo-Triazolo-Pyrimidine Derivatives as Adenosine Receptor Antagonists: A Possible Template for Adenosine Receptor Subtypes?

Baraldi, Pier, Cacciari, Barbara, Borea, Pier, Varani, Katia, Pastorin, Giorgia, Da Ros, Tatiana, Tabrizi, Mojgan, Fruttarolo, Francesca, Spalluto, Giampiero

Journal:

Current Pharmaceutical Design

Year:

2002

Language:

english

File:

PDF, 574 KB

english, 2002

76

A1 and A3 adenosine receptor agonists: an overview

Baraldi, Pier Giovanni, Cacciari, Barbara, Romagnoli, Romeo, Spalluto, Giampiero

Journal:

Expert Opinion on Therapeutic Patents

Year:

1999

Language:

english

File:

PDF, 128 KB

english, 1999

77

New 9-methyl-8-(4-hydroxyphenyl)adenine derivatives as A1 adenosine receptor antagonists

Lambertucci, Catia, Buccioni, Michela, Cacciari, Barbara, Dal Ben, Diego, Federico, Stephanie, Klotz, Karl-Norbert, Marucci, Gabriella, Volpini, Rosaria, Spalluto, Giampiero, Cristalli, Gloria

Journal:

Collection of Czechoslovak Chemical Communications

Year:

2011

Language:

english

File:

PDF, 473 KB

english, 2011

78

Cognitive Performance following Carotid Endarterectomy or Stenting in Asymptomatic Patients with Severe ICA Stenosis

Picchetto, Livio, Spalletta, Gianfranco, Casolla, Barbara, Cacciari, Claudia, Cavallari, Michele, Fantozzi, Cristiano, Ciuffoli, Alessandro, Rasura, Maurizia, Imperiale, Francesca, Sette, Giuliano, Ca

Journal:

Cardiovascular Psychiatry and Neurology

Year:

2013

Language:

english

File:

PDF, 133 KB

english, 2013

79

A2B Adenosine Receptor Antagonists: Recent Developments

Cacciari, Barbara, Pastorin, Giorgia, Bolcato, Chiara, Spalluto, Giampiero, Bacilieri, Magdalena, Moro, Stefano

Journal:

Mini Reviews in Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 149 KB

english, 2005

80

A New Synthetic Approach to Indazole Synthesis

Baraldi, Pier Giovanni, Cacciari, Barbara, Spalluto, Giampiero, Romagnoli, Romeo, Braccioli, Giovanni, Zaid,, Pineda de las Infantas, Maria J.

Journal:

Year:

1997

File:

PDF, 248 KB

1997

81

1H-Pyrazolo[2,3-d][1,2,4]triazine-3,7-diones as a New Class of Human Leukocyte Elastase Inhibitors

Baraldi, Pier, Cacciari, Barbara, Romagnoli, Romeo, Spalluto, Giampiero

Journal:

Arzneimittelforschung

Year:

2011

Language:

english

File:

PDF, 52 KB

english, 2011

82

Non Peptidic αvβ3 Antagonists: Recent Developments

Cacciari, Barbara, Spalluto, Giampiero

Journal:

Current Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 576 KB

english, 2005

83

An Efficient Procedure for the Synthesis of 5H-6-Substituted-pyrazolo[1,5-d]-1,2,4-triazine-4,7-diones

Baraldi, Pier Giovanni, Cacciari, Barbara, Romagnoli, Romeo, Spalluto, Giampiero

Journal:

Year:

1999

Language:

english

File:

PDF, 142 KB

english, 1999

84

Oligonucleotides and Oligonucleotide Conjugates: A New Approach for Cancer Treatment

Ros, Tatiana, Spalluto, Giampiero, Prato, Maurizio, Saison-Behmoaras, Tula, Boutorine, Alexandre, Cacciari, Barbara

Journal:

Current Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 541 KB

english, 2005

85

Medicinal Chemistry of A2A Adenosine Receptor Antagonists

Cacciari, Barbara, Pastorin, Giorgia, Spalluto, Giampiero

Journal:

Current Topics in Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 196 KB

english, 2003

86

5,7-Disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazines as pharmacological tools to explore the antagonist selectivity profiles toward adenosine receptors

Federico, Stephanie, Ciancetta, Antonella, Porta, Nicola, Redenti, Sara, Pastorin, Giorgia, Cacciari, Barbara, Klotz, Karl Norbert, Moro, Stefano, Spalluto, Giampiero

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.23 MB

english, 2016

87

Synthesis and Calcium Antagonist Activity of Dialkyl 1,4-Dihydro-2,6-dimethyl-4-(nitrogenous heteroaryl)-3,5-pyridine Dicarboxylates

Baraldi, Pier G., Budriesi, Roberta, Cacciari, Barbara, Chiarini, Alberto, Garuti, Laura, Giovanninetti, Giuseppe, Leoni, Alberto, Roberti, Marinella

Journal:

Collection of Czechoslovak Chemical Communications

Year:

1992

Language:

english

File:

PDF, 469 KB

english, 1992

88

Potent and Selective A2A Adenosine Receptor Antagonists: Recent Improvements

Cacciari, Barbara, Pastorin, Giorgia, Moro, Stefano, Spalluto, Giampiero

Journal:

Frontiers in Medicinal Chemistry - Online

Year:

2005

Language:

english

File:

PDF, 115 KB

english, 2005

89

Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3′,4′,5′-trimethoxyphenyl)-3-(2′-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach

Preti, Delia, Romagnoli, Romeo, Rondanin, Riccardo, Cacciari, Barbara, Hamel, Ernest, Balzarini, Jan, Liekens, Sandra, Schols, Dominique, Estévez-Sarmiento, Francisco, Quintana, José, Estévez, Francis

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.79 MB

english, 2018

90

Transperitoneal Laparoscopic Adrenalectomy in Children

Catellani, Barbara, Acciuffi, Sara, Biondini, Diego, Ceccarelli, Pier Luca, Cacciari, Alfredo, Gelmini, Roberta

Journal:

JSLS Journal of the Society of Laparoendoscopic Surgeons

Year:

2014

Language:

english

File:

PDF, 421 KB

english, 2014

91

Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3â²,4â²,5â²-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold

Romagnoli, Romeo, Prencipe, Filippo, Oliva, Paola, Cacciari, Barbara, Balzarini, Jan, Liekens, Sandra, Hamel, Ernest, Brancale, Andrea, Ferla, Salvatore, Manfredini, Stefano, Zurlo, Matteo, Finotti, A

Journal:

Year:

2020

File:

PDF, 3.85 MB

2020

92

Ethyl-(R,S)-5-acetyl-4,5-dihydro-3-isoxazole Acetate

Baraldi, Pier Giovanni, Cacciari, Barbara, Romagnoli, Romeo, Spalluto, Giampiero

Journal:

Year:

1998

File:

PDF, 91 KB

1998

93

Schematic overview of oligosaccharides, with survey on their major physiological effects and a focus on milk ones

Hanau, Stefania, Almugadam, Shawgi Hago, Sapienza, Eugenia, Cacciari, Barbara, Manfrinato, Maria Cristina, Trentini, Alessandro, Kennedy, John Frederick

Journal:

Carbohydrate Polymer Technologies and Applications

Year:

2020

File:

PDF, 1.24 MB

2020