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51

α-1-Antitrypsin: Structural relationships of the substitutions of the S and Z variants

Maurice C. Owen, Michel Lorier, Robin W. Carrell

Journal:

Year:

1978

Language:

english

File:

PDF, 161 KB

english, 1978

52

New carbohydrate site in mutant antithrombin (7 Ile→Asn) with decreased heparin affinity

Stephen O. Brennan, Jeanne-Yvonne Borg, Peter M. George, Claudine Soria, Jeannette Soria, Jacques Caen, Robin W. Carrell

Journal:

Year:

1988

Language:

english

File:

PDF, 676 KB

english, 1988

53

Antithrombin Glasgow, 393 arg to his: A P1 reactive site variant with increased heparin affinity but no thrombin inhibitory activity

Maurice C. Owen, Charles H. Beresford, Robin W. Carrell

Journal:

Year:

1988

Language:

english

File:

PDF, 965 KB

english, 1988

54

Antithrombin Cambridge, 384 Ala to Pro: A new variant identified using the polymerase chain reaction

David J. Perry, Paul L. Harper, Stuart Fairham, Martina Daly, Robin W. Carrell

Journal:

Year:

1989

Language:

english

File:

PDF, 463 KB

english, 1989

55

Antithrombin Dublin (−3 Val → Glu): an N-terminal variant which has an aberrant signal peptidase cleavage site

Martina Daly, David Bruce, David J. Perry, John Price, Paul L. Harper, Anne O'Meara, Robin W. Carrell

Journal:

Year:

1990

Language:

english

File:

PDF, 411 KB

english, 1990

56

Proteolytic inactivation of human α1 antitrypsin by human stromelysin

Paul G. Winyard, Zhi Zhang, Keith Chidwick, David R. Blake, Robin W. Carrell, Gillian Murphy

Journal:

Year:

1991

Language:

english

File:

PDF, 469 KB

english, 1991

57

Effect of alanine insertion (P′5) on the reactive centre of α1-antitrypsin

Ann Avron, Francesca H. Reeve, Josephine M. Lickorish, Robin W. Carrell

Journal:

Year:

1991

Language:

english

File:

PDF, 404 KB

english, 1991

58

How Small Peptides Block and Reverse Serpin Polymerisation

Aiwu Zhou, Penelope E. Stein, James A. Huntington, Pasupathy Sivasothy, David A. Lomas, Robin W. Carrell

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 1.13 MB

english, 2004

59

Dimers Initiate and Propagate Serine Protease Inhibitor Polymerisation

Aiwu Zhou, Robin W. Carrell

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 886 KB

english, 2008

60

The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release

Aiwu Zhou, Zhenquan Wei, Peter L.D. Stanley, Randy J. Read, Penelope E. Stein, Robin W. Carrell

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.20 MB

english, 2008

61

Angiotensinogen cleavage by renin: importance of a structurally constrained N-terminus

Rosa M.A Streatfeild-James, David Williamson, Robert N Pike, Duane Tewksbury, Robin W Carrell, Paul B Coughlin

Journal:

Year:

1998

Language:

english

File:

PDF, 149 KB

english, 1998

62

Structure of β-Antithrombin and the Effect of Glycosylation on Antithrombin's Heparin Affinity and Activity

Airlie J. McCoy, Xue Yuan Pei, Richard Skinner, Jan-Pieter Abrahams, Robin W. Carrell

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.54 MB

english, 2003

63

Association between conformational mutations in neuroserpin and onset and severity of dementia

Richard L Davis, Antony E Shrimpton, Robin W Carrell, David A Lomas, Lieselotte Gerhard, Bruno Baumann, Daniel A Lawrence, Manuel Yepes, Tai Seung Kim, Bernardino Ghetti, Pedro Piccardo, Masaki Takao,

Journal:

Year:

2002

Language:

english

File:

PDF, 1.39 MB

english, 2002

64

S3-02-04 Neuroserpin provides a structural model for the causation and rational therapy of dementia

Robin W. Carrell, Aiwu Zhou, David A. Lomas

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 313 KB

english, 2004

65

Conformational changes and disease — serpins, prions and Alzheimer's

Robin W Carrell, Bibek Gooptu

Journal:

Current Opinion in Structural Biology

Year:

1998

Language:

english

File:

PDF, 1.32 MB

english, 1998

66

Antithrombin and heparin

Robin Carrell, Richard Skinner, Mark Wardell, James Whisstock

Journal:

Molecular Medicine Today

Year:

1995

Language:

english

File:

PDF, 5.98 MB

english, 1995

67

Carboxy terminal fragment of human α-1-antitrypsin from hydroxylamine clevage: Homology with antithrombin III

Robin Carrell, Maurice Owen, Stephen Brennan, Lloyd Vaughan

Journal:

Biochemical and Biophysical Research Communications

Year:

1979

Language:

english

File:

PDF, 386 KB

english, 1979

68

Active site of α1-antitrypsin: Homologous site in antithrombin-III

Robin W. Carrell, D.Ross Boswell, Stephen O. Brennan, Maurice C. Owen

Journal:

Biochemical and Biophysical Research Communications

Year:

1980

Language:

english

File:

PDF, 206 KB

english, 1980

69

Red Cell Superoxide Dismutase Activity in the Newborn

MICHAEL LEGGE, MAUREEN BRIAN, CHRISTINE WINTERBOURN, ROBIN CARRELL

Journal:

Journal of Paediatrics and Child Health

Year:

1977

Language:

english

File:

PDF, 291 KB

english, 1977

70

How Changes in Affinity of Corticosteroid-binding Globulin Modulate Free Cortisol Concentration

Chan, Wee Lee, Carrell, Robin W., Zhou, Aiwu, Read, Randy J.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2013

Language:

english

File:

PDF, 623 KB

english, 2013

71

Alpha 1 -Antitrypsin Deficiency — A Model for Conformational Diseases

Carrell, Robin W., Lomas, David A.

Journal:

Boston Medical and Surgical Journal

Year:

2002

Language:

english

File:

PDF, 311 KB

english, 2002

72

α1-Antitrypsin and the serpins: variation and countervariation

Carrell, Robin, Travis, James

Journal:

Trends in Biochemical Sciences

Year:

1985

Language:

english

File:

PDF, 693 KB

english, 1985

73

Hermann Lehmann, 1910–1985

Carrell, Robin W.

Journal:

Trends in Biochemical Sciences

Year:

1985

Language:

english

File:

PDF, 244 KB

english, 1985

74

α1-Antitrypsin deficiency and tuberculosis

Journal:

Trends in Biochemical Sciences

Year:

1983

Language:

english

File:

PDF, 91 KB

english, 1983

75

α1-Antitrypsin: Molecules and medicine

Ross Boswell, D., Carrell, Robin

Journal:

Trends in Biochemical Sciences

Year:

1986

Language:

english

File:

PDF, 219 KB

english, 1986

76

Serpins: Mobile conformations in a family of proteinase inhibitors

Carrell, Robin W., Evans, Dyfed L.I.

Journal:

Current Opinion in Structural Biology

Year:

1992

Language:

english

File:

PDF, 936 KB

english, 1992

77

The Anticoagulant Activation of Antithrombin by Heparin

Lei Jin, Jan Pieter Abrahams, Richard Skinner, Maurice Petitou, Robert N. Pike and Robin W. Carrell

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.58 MB

english, 1997

78

Bringing Molecules to Life

Review by: Robin Carrell

Journal:

Notes and Records / the Royal Society journal of the history of science

Year:

2008

Language:

english

File:

PDF, 641 KB

english, 2008

79

Proteolysis of human native and oxidised α1-proteinase inhibitor by matrulysin and stromelysin

Zhang, Zhi, Winyard, Paul G., Chidwick, Keith, Murphy, Gillian, Wardell, Mark, Robin W., Carrell, Blake, David R.

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1994

Language:

english

File:

PDF, 601 KB

english, 1994

80

Circulating proalbumin associated with a variant proteinase inhibitor

Brennan, Stephen O., Owen, Maurice C., Boswell, D. Ross, Lewis, Jessica H., Carrell, Robin W.

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1984

Language:

english

File:

PDF, 119 KB

english, 1984

81

Heparin Binding Site, Conformational Change, and Activation of Antithrombin. [Erratum to document cited in CA118:98803]

Evans, Dyfed Ll., Marshall, Craig J., Christey, Peter B., Carrell, Robin W.

Journal:

Year:

1995

File:

PDF, 31 KB

1995

82

Preparative Induction and Characterization of L-Antithrombin: A Structural Homologue of Latent Plasminogen Activator Inhibitor-1 †

Wardell, Mark R., Chang, Wun-Shaing W., Bruce, David, Skinner, Richard, Lesk, Arthur M., Carrell, Robin W.

Journal:

Year:

1997

Language:

english

File:

PDF, 306 KB

english, 1997

83

Effect of the Z mutation on the physical and inhibitory properties of .alpha.1-antitrypsin

Lomas, David A., Evans, Dyfed L., Stone, Stuart R., Chang, Wun Shaing W., Carrell, Robin W.

Journal:

Year:

1993

Language:

english

File:

PDF, 2.07 MB

english, 1993

84

Introduction of a Mutation in the Shutter Region of Antithrombin (Phe77 → Leu) Increases Affinity for Heparin and Decreases Thermal Stability †

Quinsey, Noelene S., Fitton, Hazel L., Coughlin, Paul, Whisstock, James C., Dafforn, Timothy R., Carrell, Robin W., Bottomley, Stephen P., Pike, Robert N.

Journal:

Year:

2003

Language:

english

File:

PDF, 168 KB

english, 2003

85

Effects of mutations in the hinge region of serpins

Hopkins, Paul C. R., Carrell, Robin W., Stone, Stuart R.

Journal:

Year:

1993

Language:

english

File:

PDF, 2.05 MB

english, 1993

86

Heparin binding site, conformational change, and activation of antithrombin

Evans, Dyfed L., Marshall, Craig J., Christey, Peter B., Carrell, Robin W.

Journal:

Year:

1992

Language:

english

File:

PDF, 2.67 MB

english, 1992

87

Reactive-Centre Variants of ClrAntitrypsin. A New Range of Anti-inflammatory Agents

Carrell, Robin W.

Journal:

Biotechnology and Genetic Engineering Reviews

Year:

1986

Language:

english

File:

PDF, 1.20 MB

english, 1986

88

Haemoglobin - A Frustrated Oxidase? Implications for Red Cell Metabolism

Carrell, Robin W., Winterbourn, Christine C., French, John K.

Journal:

Year:

1977

Language:

english

File:

PDF, 403 KB

english, 1977

89

Reactivity of the p-93 Sh Groups in Hb Köln

Winterbourn, Christine C., Carrell, Robin W.

Journal:

Year:

1976

Language:

english

File:

PDF, 342 KB

english, 1976

90

Mutation of Antitrypsin to Antithrombin

Owen, Maurice C., Brennan, Stephen O., Lewis, Jessica H., Carrell, Robin W.

Journal:

Boston Medical and Surgical Journal

Year:

1983

Language:

english

File:

PDF, 3.16 MB

english, 1983

91

Kinetic Studies on the Interaction of α 1 -Proteinase Inhibitor (Pittsburgh) with Trypsin-Like Serine Proteinases

TRAVIS, James, MATHESON, Nancy R., GEORGE, Peter M., CARRELL, Robin W.

Journal:

Biological Chemistry Hoppe-Seyler

Year:

1986

File:

PDF, 2.31 MB

1986

92

What We Owe to α 1 ‐Antitrypsin and to Carl‐Bertil Laurell

Carrell, Robin W.

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Year:

2004

Language:

english

File:

PDF, 477 KB

english, 2004

93

Temperature-Responsive Release of Cortisol from Its Binding Globulin: A Protein Thermocouple

Cameron, Angus, Henley, David, Carrell, Robin, Zhou, Aiwu, Clarke, Anthony, Lightman, Stafford

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

File:

PDF, 245 KB

2010

94

Temperature-Responsive Release of Cortisol from Its Binding Globulin: A Protein Thermocouple

Cameron, Angus, Henley, David, Carrell, Robin, Zhou, Aiwu, Clarke, Anthony, Lightman, Stafford

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 245 KB

english, 2010

95

The serpins: nature's molecular Mousetraps

Huntington, James A., Carrell, Robin W.

Journal:

Science Progress

Year:

2001

Language:

english

File:

PDF, 128 KB

english, 2001

96

Conformational Changes in Serpins and the Mechanism of α 1 -Antitrypsin Deficiency

Carrell, Robin W., Whisstock, James, Lomas, David A.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

1994

Language:

english

File:

PDF, 654 KB

english, 1994

97

[Methods in Enzymology] Serpin Structure and Evolution Volume 501 || Serpins as Hormone Carriers

Year:

2011

Language:

english

File:

PDF, 646 KB

english, 2011

98

Long-term follow-up after implantation of the Shelhigh® No-React® complete biological aortic valved conduit

Reineke, David C., Kaya, Abdullah, Heinisch, Paul P., Oezdemir, Berna, Winkler, Bernhard, Huber, Christoph, Heijmen, Robin H., Morshuis, Wim, Carrel, Thierry P., Englberger, Lars

Journal:

European Journal of Cardio-Thoracic Surgery

Year:

2015

Language:

english

File:

PDF, 185 KB

english, 2015

99

P7 The effect of a reducing end extension on pentasaccharide binding by antithrombin

Belzar, Klara J., Dafforn, Timothy, Petitou, Maurice, Carrell, Robin W., Huntington, James A.

Journal:

Blood Coagulation & Fibrinolysis

Year:

1999

File:

PDF, 92 KB

1999

100

O2 Propagation of inactivation of antithrombin and the onset of thrombosis

Zhou, Aiwu, Huntington, James, Carrell, Robin

Journal:

Blood Coagulation & Fibrinolysis

Year:

1999

File:

PDF, 179 KB

1999