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51

Isoprenaline induces endothelium-independent relaxation and accumulation of cyclic nucleotides in the rat aorta

Anita E. Eckly, Jean-Claude Stoclet, Claire Lugnier

Journal:

European Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 339 KB

english, 1994

52

Drug effects on cGMP-stimulated phosphodiesterase from cardiac tissues

Narcisse Komas, Claire Lugnier, Jean-Claude Stoclet

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1990

Language:

english

File:

PDF, 96 KB

english, 1990

53

Characterization of low Km cyclic AMP phosphodiesterases from guinea pig cardiac ventricles

Bernard Muller, Claire Lugnier, Jean-Claude Stoclet

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1991

Language:

english

File:

PDF, 107 KB

english, 1991

54

G-proteins from cultured bovine aortic endothelial cells

José Gil-Longo, Claire Lugnier

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1992

Language:

english

File:

PDF, 110 KB

english, 1992

55

PDE inhibitors: a new approach to treat metabolic syndrome?

Journal:

Current Opinion in Pharmacology

Year:

2011

Language:

english

File:

PDF, 395 KB

english, 2011

56

Increased levels of cyclic adenosine monophosphate contribute to the hyporesponsiveness of mast cells in alloxan diabetes

Emiliano O Barreto, Vinicius F Carvalho, Vincent Lagente, Claire Lugnier, Renato S.B Cordeiro, Marco A Martins, Patrı́cia M.R e Silva

Journal:

International Immunopharmacology

Year:

2004

Language:

english

File:

PDF, 301 KB

english, 2004

57

Identification of PDE1 and PDE5 in adult rat left ventricular cardiomyocytes

Thérèse Keravis, Grégoire Vandecasteele, Walid Mokni, Rodolphe Fischmeister, Claire Lugnier

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2007

Language:

english

File:

PDF, 63 KB

english, 2007

58

Characterization of cyclic nucleotide phosphodiesterase isoforms associated to isolated cardiac nuclei

Claire Lugnier, Thérèse Keravis, Alain Le Bec, Olivier Pauvert, Sonia Proteau, Eric Rousseau

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1999

Language:

english

File:

PDF, 482 KB

english, 1999

59

Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors

Narcisse Komas, Claire Lugnier, Jean-Claude Stoclet

Journal:

British Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 1.68 MB

english, 1991

60

Multiple actions of glaucine on cyclic nucleotide phosphodiesterases, α1-adrenoceptor and benzothiazepine binding site at the calcium channel

M. Dolores Ivorra, Claire Lugnier, Christa Schott, Maria Catret, M. Antonia Noguera, Elsa Anselmi, Pilar D'Ocon

Journal:

British Journal of Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.50 MB

english, 1992

61

Investigations of the dual contractile/relaxant properties showed by antioquine in rat aorta

M. Dolores Ivorra, Claire Lugnier, Maria Catret, Elsa Anselmi, Diego Cortes, Pilar D'Ocon

Journal:

British Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 1.57 MB

english, 1993

62

Role of phosphodiesterases III and IV in the modulation of vascular cyclic AMP content by the NO/cyclic GMP pathway

Anita E. Eckly, Claire Lugnier

Journal:

British Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.20 MB

english, 1994

63

Mechanism of the cardiovascular activity of laudanosine: comparison with papaverine and other benzylisoquinolines

Susana Chuliá, M. Dolores Ivorra, Claire Lugnier, Elisabeth Vila, M. Antonia Noguera, Pilar D'Ocon

Journal:

British Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.55 MB

english, 1994

64

Thymoquinone reduces migration and invasion of human glioblastoma cells associated with FAK, MMP-2 and MMP-9 down-regulation

Kaouther Kolli-Bouhafs, Abdelaziz Boukhari, Abdurazzag Abusnina, Emilie Velot, Jean-Pierre Gies, Claire Lugnier, Philippe Rondé

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 973 KB

english, 2012

65

Variations in endogenous phosphodiesterase activator content of rat aorta

Claire Lugnier, Brigitte Ilien, Jean-Claude Stoclet

Journal:

European Journal of Pharmacology

Year:

1978

Language:

english

File:

PDF, 267 KB

english, 1978

66

Chelerythrine, a protein kinase C inhibitor, interacts with cyclic nucleotide phosphodiesterases

Anita E Eckly-Michel, Alain Le Bec, Claire Lugnier

Journal:

European Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 154 KB

english, 1997

67

Cyclic Nucleotides and Calcium Regulation in Heart and Smooth Muscle Cells

JEAN-CLAUDE STOCLET, CHANTAL BOULANGER-SAUNIER, BERNARD LASSEGUE, CLAIRE LUGNIER

Journal:

Annals of the New York Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 617 KB

english, 1988

68

Design, Synthesis, and Pharmacological Evaluation of N -Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active Phosphodiesterase-4 Inhibitors

Kümmerle, Arthur E., Schmitt, Martine, Cardozo, Suzana V. S., Lugnier, Claire, Villa, Pascal, Lopes, Alexandra B., Romeiro, Nelilma C., Justiniano, Hélène, Martins, Marco A., Fraga, Carlos A. M., Bour

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.46 MB

english, 2012

69

Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogs

Marivet, Michel C., Bourguignon, Jean Jacques, Lugnier, Claire, Mann, Andre, Stoclet, Jean Claude, Wermuth, Camille Georges

Journal:

Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 933 KB

english, 1989

70

Design of Small-Sized Libraries by Combinatorial Assembly of Linkers and Functional Groups to a Given Scaffold: Application to the Structure-Based Optimization of a Phosphodiesterase 4 Inhibitor

Krier, Mireille, de Araújo-Júnior, João X., Schmitt, Martine, Duranton, Jérôme, Justiano-Basaran, Hélène, Lugnier, Claire, Bourguignon, Jean-Jacques, Rognan, Didier

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 551 KB

english, 2005

71

9-Benzyladenines: Potent and Selective cAMP Phosphodiesterase Inhibitors

Bourguignon, Jean-Jacques, Désaubry, Laurent, Raboisson, Pierre, Wermuth, Camille-Georges, Lugnier, Claire

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 94 KB

english, 1997

72

Phosphodiesterase Methods and Protocols Volume 307 || Identification of Promoter Elements in 5'-Flanking Region of Murine Cyclic Nucleotide Phosphodiesterase 3B Gene

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

73

Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling

Yougbaré, Issaka, Keravis, Thérèse, Abusnina, Abdurazzag, Decossas, Marion, Schall, Nicolas, Muller, Sylviane, Lugnier, Claire

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2014

Language:

english

File:

PDF, 1.27 MB

english, 2014

74

Negative Feedback Exerted by cAMP-dependent Protein Kinase and cAMP Phosphodiesterase on Subsarcolemmal cAMP Signals in Intact Cardiac Myocytes

Rochais, Francesca, Vandecasteele, Grégoire, Lefebvre, Florence, Lugnier, Claire, Lum, Hazel, Mazet, Jean-Luc, Cooper, Dermot M. F., Fischmeister, Rodolphe

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 1014 KB

english, 2004

75

NCS 613 exhibits anti-inflammatory effects on PBMCs from lupus patients by inhibiting p38 MAPK and NF-κB signalling pathways while reducing proinflammatory cytokine production

Yougbaré, Issaka, Boire, Gilles, Roy, Michelle, Lugnier, Claire, Rouseau, Éric

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

2013

File:

PDF, 1.39 MB

2013

76

Specific cyclic nucleotide phosphodiesterase inhibitors differently modulate contractile kinetics in airway smooth muscle

Rousseau, Eric, Dostie, Josée, Beaudry, Catherine, Taoudi-Benchekroun, Majda, Cadieux, Alain, Lugnier, Claire

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.07 MB

english, 1995

77

Phosphodiesterase Methods and Protocols Volume 307 ||

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 5.49 MB

english, 2005

78

Section Review: Cardiovascular & Renal: Cyclic nucleotide phosphodiesterases as therapeutic targets in cardiovascular diseases

Stoclet, Jean-Claude, Keravis, Thérèse, Komas, Narcisse, Lugnier, Claire

Journal:

Expert Opinion on Investigational Drugs

Year:

1995

Language:

english

File:

PDF, 2.00 MB

english, 1995

79

Disease Progression in MRL/lpr Lupus-Prone Mice Is Reduced by NCS 613, a Specific Cyclic Nucleotide Phosphodiesterase Type 4 (PDE4) Inhibitor

Keravis, Thérèse, Monneaux, Fanny, Yougbaré, Issaka, Gazi, Lucien, Bourguignon, Jean-Jacques, Muller, Sylviane, Lugnier, Claire, Bobé, Pierre

Journal:

Year:

2012

Language:

english

File:

PDF, 503 KB

english, 2012

80

Cyclic Nucleotide Hydrolysis in Bovine Aortic Endothelial Cells in Culture: Differential Regulation in Cobblestone and Spindle Phenotypes

Keravis, Th&eacute, r&egrave, se, Komas, Narcisse, Lugnier, Claire

Journal:

Journal of Vascular Research

Year:

2000

Language:

english

File:

PDF, 820 KB

english, 2000

81

Reverse Pharmacognosy: Application of Selnergy, a New Tool for Lead Discovery. The Example of ε-Viniferin

Do, Quoc-Tuan, Renimel, Isabelle, Andre, Patrice, Lugnier, Claire, Muller, Christian, Bernard, Philippe

Journal:

Current Drug Discovery Technologies

Year:

2005

Language:

english

File:

PDF, 143 KB

english, 2005

82

Biflavones of Decussocarpus rospigliosii as Phosphodiesterases Inhibitors

Chaabi, Mehdi, Antheaume, Cyril, Weniger, Bernard, Justiniano, Hélène, Lugnier, Claire, Lobstein, Annelise

Journal:

Year:

2007

Language:

english

File:

PDF, 112 KB

english, 2007

83

Implication of Cyclic Nucleotide Phosphodiesterase Inhibition in the Vasorelaxant Activity of the Citrus-Fruits Flavonoid (±)-Naringenin

Orallo, Francisco, Camiña, Mercedes, Álvarez, Ezequiel, Basaran, Hélène, Lugnier, Claire

Journal:

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

84

Phosphodiesterase Methods and Protocols Volume 307 || Study of Cyclic Adenosine Monophosphate Microdomains in Cells

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 333 KB

english, 2005

85

Phosphodiesterase Methods and Protocols Volume 307 || Cyclic Guanosine 5'-Monophosphate Binding to Regulatory GAF Domains of Photoreceptor Phosphodiesterase

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 134 KB

english, 2005

86

Phosphodiesterase Methods and Protocols Volume 307 || Generation of PDE4 Knockout Mice by Gene Targeting

Lugnier, Claire

Year:

2005

File:

PDF, 197 KB

2005

87

Phosphodiesterase Methods and Protocols Volume 307 || Purification of PDE6 Isozymes From Mammalian Retina

Lugnier, Claire

Year:

2005

File:

PDF, 246 KB

2005

88

Phosphodiesterase Methods and Protocols Volume 307 || Determination of Ca2+/Calmodulin-Stimulated Phosphodiesterase Activity in Intact Cells

Lugnier, Claire

Year:

2005

File:

PDF, 134 KB

2005

89

Phosphodiesterase Methods and Protocols Volume 307 || High-Throughput Screening of Phosphodiesterase Activity in Living Cells

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 187 KB

english, 2005

90

Phosphodiesterase Methods and Protocols Volume 307 || High-Resolution Measurements of Cyclic Adenosine Monophosphate Signals in 3D Microdomains

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 151 KB

english, 2005

91

Phosphodiesterase Methods and Protocols Volume 307 || Investigation of Extracellular Signal-Regulated Kinase 2 Mitogen-Activated Protein Kinase Phosphorylation and Regulation of Activity of PDE4 Cyclic Adenosine Monophosphate-Specific Phosphodiesterases

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 175 KB

english, 2005

92

Phosphodiesterase Methods and Protocols Volume 307 || Renaturation of the Catalytic Domain of PDE4A Expressed in Escherichia coli as Inclusion Bodies

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 146 KB

english, 2005

93

Phosphodiesterase Methods and Protocols Volume 307 || Determination of Ca2+/Calmodulin-Stimulated Phosphodiesterase Activity in Intact Cells

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 134 KB

english, 2005

94

Phosphodiesterase Methods and Protocols Volume 307 || Purification of PDE6 Isozymes From Mammalian Retina

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 246 KB

english, 2005

95

Phosphodiesterase Methods and Protocols Volume 307 || Generation of PDE4 Knockout Mice by Gene Targeting

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 197 KB

english, 2005

96

Postnatal Maturation of Phosphodiesterase 5 (PDE5) in Piglet Pulmonary Arteries: Activity, Expression, Effects of PDE5 Inhibitors, and Role of the Nitric Oxide/Cyclic GMP Pathway

Moreno, Laura, Losada, Begoña, Cogolludo, Angel L, Lodi, Federica, Lugnier, Claire, Villamor, Eduardo, Moro, Manuel, Tamargo, Juan, Pérez-Vizcaíno, Francisco

Journal:

Pediatric Research

Year:

2004

Language:

english

File:

PDF, 279 KB

english, 2004

97

Phosphodiesterase Methods and Protocols Volume 307 || Radiolabeled Ligand Binding to the Catalytic or Allosteric Sites of PDE5 and PDE11

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 453 KB

english, 2005

98

Phosphodiesterase Methods and Protocols Volume 307 || Immunoprecipitation of PDE2 Phosphorylated and Inactivated by an Associated Protein Kinase

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 206 KB

english, 2005

99

Phosphodiesterase Methods and Protocols Volume 307 || Interactions Between Catalytic and Inhibitory Subunits of PDE6

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 138 KB

english, 2005

100

Phosphodiesterase Methods and Protocols Volume 307 || Purification, Reconstitution on Lipid Vesicles, and Assays of PDE6 and Its Activator G Protein, Transducin

Lugnier, Claire

Year:

2005

Language:

english

File:

PDF, 177 KB

english, 2005

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