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51

Synthesis and antiviral activity of water-soluble esters of acyclovir [9-[(2-hydroxyethoxy)methyl]guanine)

Colla, Leon, De Clercq, Erik, Busson, Roger, Vanderhaeghe, Hubert

Journal:

Journal of Medicinal Chemistry

Year:

1983

Language:

english

File:

PDF, 467 KB

english, 1983

52

Current race in the development of DAAs (direct-acting antivirals) against HCV

De Clercq, Erik

Journal:

Biochemical Pharmacology

Year:

2014

Language:

english

File:

PDF, 472 KB

english, 2014

53

Single carbon nanotube plucked by nano-tweezers

De Clercq, Erik, Eckstein, Fritz, Sternbach, Hans, Merigan, Thomas C.

Journal:

Year:

2007

Language:

english

File:

PDF, 117 KB

english, 2007

54

Biological Evaluation of Proanthocyanidin Dimers and Related Polyphenols

De Bruyne, Tess, Pieters, Luc, Witvrouw, Myriam, De Clercq, Erik, Vanden Berghe, Dirk, Vlietinck, Arnold J.

Journal:

Journal of Natural Products

Year:

1999

Language:

english

File:

PDF, 70 KB

english, 1999

55

Design and Synthesis of Hydroxyferroquine Derivatives with Antimalarial and Antiviral Activities

Biot, Christophe, Daher, Wassim, Chavain, Natascha, Fandeur, Thierry, Khalife, Jamal, Dive, Daniel, De Clercq, Erik

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 64 KB

english, 2006

56

Correlation of Anti-HIV Activity with Anion Spacing in a Series of Cosalane Analogues with Extended Polycarboxylate Pharmacophores

Santhosh, Kalpathy C., Paul, Gitendra C., De Clercq, Erik, Pannecouque, Christophe, Witvrouw, Myriam, Loftus, Tracy L., Turpin, Jim A., Buckheit,, Robert W., Cushman, Mark

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 257 KB

english, 2001

57

Scapular Muscle Recruitment Pattern: Electromyographic Response of the Trapezius Muscle to Sudden Shoulder Movement Before and After a Fatiguing Exercise

Cools, Ann M., Witvrouw, Erik E., De Clercq, Geert A., Danneels, Lieven A., Willems, Tine M., Cambier, Dirk C., Voight, Michael L.

Journal:

Journal of Orthopaedic and Sports Physical Therapy

Year:

2002

Language:

english

File:

PDF, 75 KB

english, 2002

58

Synthesis and Biological Evaluation of a Series of Substituted 2-Pyridine C-Nucleosides

Belmans, Marc, Esmans, Eddy, Dommisse, Roger, Lepoivre, Jozef, Alderweireldt, Frank, Balzarini, Jan, De Clercq, Erik

Journal:

Nucleosides and Nucleotides

Year:

1985

Language:

english

File:

PDF, 603 KB

english, 1985

59

Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections

De Clercq, Erik, Férir, Geoffrey, Kaptein, Suzanne, Neyts, Johan

Journal:

Year:

2010

Language:

english

File:

PDF, 918 KB

english, 2010

60

Historical Perspectives in the Development of Antiviral Agents Against Poxviruses

De Clercq, Erik

Journal:

Year:

2010

Language:

english

File:

PDF, 932 KB

english, 2010

61

Design, Synthesis, Anti-HIV Activities, and Metabolic Stabilities of Alkenyldiarylmethane (ADAM) Non-nucleoside Reverse Transcriptase Inhibitors

Silvestri, Maximilian A., Nagarajan, Muthukaman, De Clercq, Erik, Pannecouque, Christophe, Cushman, Mark

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 312 KB

english, 2004

62

New perspectives for the design of sustainable bioprocesses for phosphorus recovery from waste

Tarayre, Cédric, Clercq, Lies De, Charlier, Raphaëlle, Michels, Evi, Meers, Erik, Camargo-Valero, Miller, Delvigne, Frank

Journal:

Bioresource Technology

Year:

2016

Language:

english

File:

PDF, 1.23 MB

english, 2016

63

Antivirals: current state of the art

De Clercq, Erik

Journal:

Future Virology

Year:

2008

Language:

english

File:

PDF, 1.71 MB

english, 2008

64

Approved Antiviral Drugs over the Past 50 Years

De Clercq, Erik, Li, Guangdi

Journal:

Clinical Microbiology Reviews

Year:

2016

Language:

english

File:

PDF, 9.36 MB

english, 2016

65

Gait-Related Risk Factors for Exercise-Related Lower-Leg Pain during Shod Running

WILLEMS, TINE MARIEKE, WITVROUW, ERIK, DE COCK, ANNELEEN, DE CLERCQ, DIRK

Journal:

Medicine & Science in Sports & Exercise

Year:

2007

Language:

english

File:

PDF, 236 KB

english, 2007

66

Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.

Saboulard, Didier, Naesens, Lieve, Cahard, Dominique, Salgado, Antonio, Pathirana, Ranjith, Velazquez, Sonsoles, McGuigan, Christopher, {De Clercq}, Erik, Balzarini, Jan

Journal:

Molecular Pharmacology

Year:

1999

Language:

english

File:

PDF, 212 KB

english, 1999

67

Injury prevention in physical education teacher education students: lessons from sports. A systematic review

Goossens, Lennert, De Ridder, Roel, Cardon, Greet, Witvrouw, Erik, Verrelst, Ruth, De Clercq, Dirk

Journal:

European Physical Education Review

Year:

2017

Language:

english

File:

PDF, 317 KB

english, 2017

68

The discovery of novel diarylpyri(mi)dine derivatives with high level activity against a wide variety of HIV-1 strains as well as against HIV-2

Lu, Xueyi, Yang, Jiapei, Kang, Dongwei, Gao, Ping, Daelemans, Dirk, De Clercq, Erik, Pannecouque, Christophe, Zhan, Peng, Liu, Xinyong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

69

Characterisation of Phosphate Accumulating Organisms and Techniques for Polyphosphate Detection: A Review

Tarayre, Cédric, Nguyen, Huu-Thanh, Brognaux, Alison, Delepierre, Anissa, De Clercq, Lies, Charlier, Raphaëlle, Michels, Evi, Meers, Erik, Delvigne, Frank

Journal:

Year:

2016

Language:

english

File:

PDF, 965 KB

english, 2016

70

Fifty years in search of selective antiviral drugs

De Clercq, Erik

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 702 KB

english, 2019

71

An E460D substitution in the NS5 protein of tick-borne encephalitis virus confers resistance to the inhibitor Galidesivir (BCX4430) and also attenuates the virus for mice

Eyer, Ludek, Nougairède, Antoine, Uhlířová, Marie, Driouich, Jean-Sélim, Zouharová, Darina, Valdés, James J., Haviernik, Jan, Gould, Ernest A., De Clercq, Erik, de Lamballerie, Xavier, Ruzek, Daniel

Journal:

Journal of Virology

Year:

2019

Language:

english

File:

PDF, 3.60 MB

english, 2019

72

Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities

Sun, Lin, Dick, Alexej, Meuser, Megan E., Huang, Tianguang, Zalloum, Waleed A., Chen, Chin-Ho, Cherukupalli, Srinivasulu, Xu, Shujing, Ding, Xiao, Gao, Ping, Kang, Dongwei, De Clercq, Erik, Pannecouqu

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 906 KB

2020

73

Treatment of severe laryngeal papillomatosis with intralesional injections of cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine]

Snoeck, Robert, Wellens, Willy, Desloovere, Christian, Ranst, Mark Van, Naesens, Lieve, De Clercq, Erik, Feenstra, Louw

Journal:

Journal of Medical Virology

Year:

1998

Language:

english

File:

PDF, 234 KB

english, 1998

74

Treatment of classical Kaposi's sarcoma with intralesional injections of cidofovir: Report of a case

Simonart, Thierry, Noel, Jean-Christophe, De Dobbeleer, Gilbert, Parent, Dominique, Van Vooren, Jean-Paul, De Clercq, Erik, Snoeck, Robert

Journal:

Journal of Medical Virology

Year:

1998

Language:

english

File:

PDF, 135 KB

english, 1998

75

Cidofovir, a new approach for the treatment of cervix intraepithelial neoplasia grade III (CIN III)

Snoeck, Robert, Noel, Jean-Christophe, Muller, Christine, De Clercq, Erik, Bossens, Michel

Journal:

Journal of Medical Virology

Year:

2000

Language:

english

File:

PDF, 1.18 MB

english, 2000

76

Hydrogels containing monocaprin prevent intravaginal and intracutaneous infections with HSV-2 in mice: Impact on the search for vaginal microbicides

Neyts, Johan, Kristmundsd�ttir, T., De Clercq, Erik, Thormar, Halldor

Journal:

Journal of Medical Virology

Year:

2000

Language:

english

File:

PDF, 156 KB

english, 2000

77

Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands

John N. Champness, Matthew S. Bennett, Frank Wien, Rob Visse, William C. Summers, Piet Herdewijn, Erik de Clercq, Tomasz Ostrowski, Richard L. Jarvest, Mark R. Sanderson

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1998

Language:

english

File:

PDF, 947 KB

english, 1998

78

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment of human immunodeficiency virus type 1 (HIV-1) infections: Strategies to overcome drug resistance development

Journal:

Medicinal Research Reviews

Year:

1996

Language:

english

File:

PDF, 3.07 MB

english, 1996

79

The HIV-1 Reverse Transcription (RT) Process as Target for RT Inhibitors

Heidi Jonckheere, Jozef Anné, Erik De Clercq

Journal:

Medicinal Research Reviews

Year:

2000

Language:

english

File:

PDF, 608 KB

english, 2000

80

Charge modification of plasma and milk proteins results in antiviral active compounds

Pieter J. Swart, Martin C. Harmsen, Mirjam E. Kuipers, Alard A. Van Dijk, Barry W.A. Van Der Strate, Patrick H.C. Van Berkel, Jan H. Nuijens, Catharina Smit, Miryam Witvrouw, Erik De Clercq, Marie-Pie

Journal:

Journal of Peptide Science

Year:

1999

Language:

english

File:

PDF, 169 KB

english, 1999

81

What can be Expected from Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs) in the Treatment of Human Immunodeficiency Virus Type 1 (HIV-1) Infections?

Journal:

Reviews in Medical Virology

Year:

1996

Language:

english

File:

PDF, 2.37 MB

english, 1996

82

Synthesis and Antiviral and Cytostatic Activities of Carbocyclic Nucleosides Incorporating a Modified Cyclobutane Ring

M. José Figueira, J. Manuel Blanco, Olga Caamaño, Franco Fernández, Xerardo García-Mera, Carmen López, Graciela Andrei, Robert Snoeck, Elisabeth Padalko, Johan Neyts, Jan Balzarini, Erik De Clercq

Journal:

Archiv der Pharmazie

Year:

1999

Language:

english

File:

PDF, 81 KB

english, 1999

83

Inhibition of Human Immunodeficiency Virus Type (HIV-1) Replication by some Diversely Functionalized Spirocyclopropyl Derivatives

Myriam Witvrouw, Christophe Pannecouque, Erik De Clercq, Eldiberto Fernández-Alvarez, José L. Marco

Journal:

Archiv der Pharmazie

Year:

1999

Language:

english

File:

PDF, 73 KB

english, 1999

84

Potent inhibition of hemangiosarcoma development in mice by cidofovir

Sandra Liekens, Erik Verbeken, Erik De Clercq, Johan Neyts

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 311 KB

english, 2001

85

Current lead natural products for the chemotherapy of human immunodeficiency virus (HIV) infection

Journal:

Medicinal Research Reviews

Year:

2000

Language:

english

File:

PDF, 444 KB

english, 2000

86

Novel compounds in preclinical/early clinical development for the treatment of HIV infections

Journal:

Reviews in Medical Virology

Year:

2000

Language:

english

File:

PDF, 447 KB

english, 2000

87

Diverging binding capacities of natural LD78β isoforms of macrophage inflammatory protein-1α to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophils

Sofie Struyf, Patricia Menten, Jean-Pierre Lenaerts, Willy Put, Anne D'Haese, Erik De Clercq, Dominique Schols, Paul Proost, Jo Van Damme

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 160 KB

english, 2001

88

1,2,4-Triazole Derivatives Inhibiting the Human Immunodeficiency Virus Type 1 (HIV-1) in vitro

Irene M. Lagoja, Christophe Pannecouque, Laura Musumeci, Matheus Froeyen, Arthur Van Aerschot, Jan Balzarini, Piet Herdewijn, Erik De Clercq

Journal:

Helvetica Chimica Acta

Year:

2002

Language:

english

File:

PDF, 150 KB

english, 2002

89

Chemo-Enzymatic Synthesis of 3-Deoxy-β-D-ribofuranosyl Purines

Vladimir N. Barai, Anatoli I. Zinchenko, Ludmilla A. Eroshevskaya, Elena V. Zhernosek, Erik De Clercq, Igor A. Mikhailopulo

Journal:

Helvetica Chimica Acta

Year:

2002

Language:

english

File:

PDF, 93 KB

english, 2002

90

Pridine Oxide Derivatives: Structure-Activity Relationship for Inhibition of Human Immunodeficiency Virus and Cytomegalovirus Replication in Cell Culture

Jan Balzarini, Miguel Stevens, Graciela Andrei, Robert Snoeck, Richard Strunk, James B. Pierce, John A. Lacadie, Erik De Clercq, Christophe Pannecouque

Journal:

Helvetica Chimica Acta

Year:

2002

Language:

english

File:

PDF, 135 KB

english, 2002

91

Palladium-Catalyzed Aryl Amination Reactions of 6-Bromo- and 6-Chloropurine Nucleosides

Paul F. Thomson, Pallavi Lagisetty, Jan Balzarini, Erik De Clercq, Mahesh K. Lakshman

Journal:

Advanced Synthesis & Catalysis

Year:

2010

Language:

english

File:

PDF, 225 KB

english, 2010

92

Assessment of the in vitro broad-spectrum antiviral activity of some selected antitumor metallocene and metallocenium complexes

Sarah G Ward, R Craig Taylor, Petra Köpf-Maier, Hartmut Köpf, Jan Balzarini, Erik De Clercq

Journal:

Applied Organometallic Chemistry

Year:

1989

Language:

english

File:

PDF, 540 KB

english, 1989

93

Assessment of the in vitro broad-spectrum antiviral activity of some selected antitumor organotin complexes

Sarah G Ward, R Craig Taylor, Alan J Crowe, Jan Balzarini, Erik De Clercq

Journal:

Applied Organometallic Chemistry

Year:

1989

Language:

english

File:

PDF, 461 KB

english, 1989

94

Syntheses and Antiviral Activities of Some 5′-O-Acyl Derivatives

Klaus Keppeler, Gebhard Kiefer, Erik De Clercq

Journal:

Archiv der Pharmazie

Year:

1984

Language:

english

File:

PDF, 341 KB

english, 1984

95

Prodrugs of 5-Ethyl-2′-deoxyuridine, II Syntheses and Antiviral Activities of 5′- and 3′-Ester Derivatives

Gebhard Kiefer, Klaus Keppeler, Erik De Clercq

Journal:

Archiv der Pharmazie

Year:

1986

Language:

english

File:

PDF, 318 KB

english, 1986

96

Synthesis and Antiviral Activity of Acyclic Derivatives of 5-Ethyl-2′-Deoxyuridine

Klaus Keppeler, Gebhard Kiefer, Erik de Clercq

Journal:

Archiv der Pharmazie

Year:

1986

Language:

english

File:

PDF, 298 KB

english, 1986

97

Synthese und antivirale Aktivität von 2,3(1H, 4H)-Chinoxalindion-Derivaten

Klaus Keppeler, Erik De Clercq

Journal:

Archiv der Pharmazie

Year:

1987

File:

PDF, 214 KB

1987

98

Novel Carbocyclic Nucleosides Containing a Cyclopentyl Ring. Adenosine and Uridine Analogues

Carmen Balo, Franco Fernández, Evangelina Lens, Carmen López, Graciela Andrei, Robert Snoeck, Jan Balzarini, Erik De Clercq

Journal:

Archiv der Pharmazie

Year:

1997

Language:

english

File:

PDF, 339 KB

english, 1997

99

Non-nucleoside HIV Reverse Transcriptase Inhibitors, Part 6[1]: Synthesis and Anti-HIV Activity of Novel 2-[(Arylcarbonylmethyl)thio]-6-arylthio DABO Analogues

Guang-Fu Sun, Yun-Yan Kuang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque

Journal:

Archiv der Pharmazie

Year:

2005

Language:

english

File:

PDF, 91 KB

english, 2005

100

Synthesis and Anti-HIV Activity Evaluation of Novel 2,4-Disubstituted 7-Methyl-1,1,3-trioxo-2,4-dihydro-pyrazolo-[4,5-e][1,2]thiadiazines

Xin-yong Liu, Ren-zhang Yan, Yan Wang, Peng Zhan, Erik De Clercq, Christophe Pannecouque, Myriam Witvrouw, Maria Teresa Molina, Salvador Vega

Journal:

Archiv der Pharmazie

Year:

2008

Language:

english

File:

PDF, 398 KB

english, 2008

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