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1

Estimating the safe starting dose in phase I clinical trials and no observed effect level based on QSAR modeling of the human maximum recommended daily dose

Joseph F. Contrera, Edwin J. Matthews, Naomi L. Kruhlak, R. Daniel Benz

Journal:

Regulatory Toxicology and Pharmacology

Year:

2004

Language:

english

File:

PDF, 491 KB

english, 2004

2

Predicting the carcinogenic potential of pharmaceuticals in rodents using molecular structural similarity and E-state indices

Joseph F Contrera, Edwin J Matthews, R Daniel Benz

Journal:

Regulatory Toxicology and Pharmacology

Year:

2003

Language:

english

File:

PDF, 389 KB

english, 2003

3

AIP Conference Proceedings [AIP XII MEXICAN WORKSHOP ON PARTICLES AND FIELDS - Mazatlán, (Mexico) (9–14 November 2009)] - Introduction to effective Lagrangians for QCD

Schechter, Joseph, Ayala, Alejandro, Contreras, Guillermo, Leon, Ildefonso, Podesta, Pedro

Year:

2011

Language:

english

File:

PDF, 708 KB

english, 2011

4

Validation of Toxtree and SciQSAR in silico predictive software using a publicly available benchmark mutagenicity database and their applicability for the qualification of impurities in pharmaceuticals

Contrera, Joseph F.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2013

Language:

english

File:

PDF, 522 KB

english, 2013

5

Association of Self-efficacy for Fruit and Vegetable Intake with Reported Dietary Intake in 5th Grade Children

Santiago Rivera, Olga J., Carlson, Joseph, Eisenmann, J.C., Pfeiffer, K., Feltz, D., Avila, B., Contreras, D.

Journal:

Journal of Nutrition Education and Behavior

Year:

2013

Language:

english

File:

PDF, 68 KB

english, 2013

6

Reviews

Moore, Joseph Price, Contreras, Antonio

Journal:

Capitalism Nature Socialism

Year:

1994

Language:

english

File:

PDF, 425 KB

english, 1994

7

Conservation Status of Imperiled North American Freshwater and Diadromous Fishes

Jelks, Howard L., Walsh, Stephen J., Burkhead, Noel M., Contreras-Balderas, Salvador, Diaz-Pardo, Edmundo, Hendrickson, Dean A., Lyons, John, Mandrak, Nicholas E., McCormick, Frank, Nelson, Joseph S.,

Journal:

Year:

2008

Language:

english

File:

PDF, 15.65 MB

english, 2008

8

Vocational training and employment attainment among substance abuse recovering individuals within a communal living environment

Gomez, Daisy, A. Jason, Leonard, Contreras, Richard, DiGangi, Julia, R. Ferrari, Joseph

Journal:

Therapeutic Communities The International Journal of Therapeutic Communities

Year:

2014

Language:

english

File:

PDF, 227 KB

english, 2014

9

Catheter Ablation of Atypical Atrioventricular Nodal Reentrant Tachycardia

Katritsis, Demosthenes G., Marine, Joseph E., Contreras, Fernando M., Fujii, Akira, Latchamsetty, Rakesh, Siontis, Konstantinos C., Katritsis, George D., Zografos, Theodoros A., John, Roy M., Epstein,

Journal:

Year:

2016

Language:

english

File:

PDF, 1.55 MB

english, 2016

10

Pharmacological mechanisms of alcohol analgesic-like properties in mouse models of acute and chronic pain

Neddenriep, Bradley, Bagdas, Deniz, Contreras, Katherine M., Ditre, Joseph W., Wolstenholme, Jennifer T., Miles, Michael F., Damaj, M. Imad

Journal:

Neuropharmacology

Year:

2019

Language:

english

File:

PDF, 1018 KB

english, 2019

11

Comparisons of Vaccine Hesitancy across Five Low- and Middle-Income Countries

Wagner, Abram L., Masters, Nina B., Domek, Gretchen J., Mathew, Joseph L., Sun, Xiaodong, Asturias, Edwin J., Ren, Jia, Huang, Zhuoying, Contreras-Roldan, Ingrid L., Gebremeskel, Berhanu, Boulton, Mat

Journal:

Year:

2019

Language:

english

File:

PDF, 612 KB

english, 2019

12

[IEEE 2019 53rd Asilomar Conference on Signals, Systems, and Computers - Pacific Grove, CA, USA (2019.11.3-2019.11.6)] 2019 53rd Asilomar Conference on Signals, Systems, and Computers - Real-Time Seizure State Tracking Using Two Channels: A Mixed-Filter Approach

Ahmadi, Mohammad Badri, Craik, Alexander, Azgomi, Hamid Fekri, Francis, Joseph T., Contreras-Vidal, Jose L., Faghih, Rose T.

Year:

2019

File:

PDF, 13.75 MB

2019

13

ChemInform Abstract: Synthesis of Indolylindolines Mediated by t-BuNH2.

Oscar R. Suarez-Castillo, Myriam Melendez-Rodriguez, Ana L. Morales-Garcia, Indira C. Cano-Escudero, Yaneth M. A. Contreras-Martinez, Martha S. Morales-Rios, Pedro Joseph-Nathan

Journal:

Year:

2009

Language:

english

File:

PDF, 25 KB

english, 2009

14

Syntheses and structures of two new dibenzobicyclic phenylboronates

Norberto Farfán, Pedro Joseph-Nathan, Luis Manuel Chiquete, Rosalinda Contreras

Journal:

Journal of Organometallic Chemistry

Year:

1988

Language:

english

File:

PDF, 439 KB

english, 1988

15

NMR and X-ray diffraction studies of two bicyclic borates containing chiral boron and nitrogen atoms

Norberto Farfán, Teresa Mancilla, Dolores Castillo, Guillermo Uribe, Lourdes Carrillo, Pedro Joseph-Nathan, Rosalinda Contreras

Journal:

Journal of Organometallic Chemistry

Year:

1990

Language:

english

File:

PDF, 705 KB

english, 1990

16

Coordination compounds derived from the interaction of streptomycin and cobalt, nickel, copper, and calcium salts characterized by 13C NMR and spectroscopic studies. Structure and bonding properties of the streptidine fraction

Norah Barba-Behrens, Juan L. Bautista, M.Esther Ruiz, Pedro Joseph-Nathan, Angelina Flores-Parra, Rosalinda Contreras

Journal:

Journal of Inorganic Biochemistry

Year:

1990

Language:

english

File:

PDF, 836 KB

english, 1990

17

Hand-Portable Gas Chromatograph-Toroidal Ion Trap Mass Spectrometer (GC-TMS) for Detection of Hazardous Compounds

Jesse A. Contreras, Jacolin A. Murray, Samuel E. Tolley, Joseph L. Oliphant, H. Dennis Tolley, Stephen A. Lammert, Edgar D. Lee, Douglas W. Later, Milton L. Lee

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2008

Language:

english

File:

PDF, 1.06 MB

english, 2008

18

Conformational studies of N-carbomethoxy-2-alkoxyindolenines by dynamic NMR, crystallography, and molecular mechanics

Oscar R. Suárez-Castillo, Yaneth M.A. Contreras-Martínez, Lidia Beiza-Granados, Myriam Meléndez-Rodríguez, J. Roberto Villagómez-Ibarra, J. Martín Torres-Valencia, Martha S. Morales-Ríos, Pedro Joseph

Journal:

Year:

2005

Language:

english

File:

PDF, 998 KB

english, 2005

19

Response to Monro and Mehta proposal for use of single-dose toxicology studies to support single-dose studies of new drugs in humans

Choudary, Jasti, Contrera, Joseph F., DeFelice, Albert, DeGeorge, Joseph J., Farrelly, James G., Fitzgerald, Glenna, Goheer, M. Anwar, Jacobs, Abby, Jordan, Alexander, Meyers, Laraine, Osterberg, Robe

Journal:

Clinical Pharmacology & Therapeutics

Year:

1996

Language:

english

File:

PDF, 297 KB

english, 1996

20

Preparation of new quinic acid boron esters in aprotic media

Angelina Flores-Parra, Concepción Paredes-Tepox, Pedro Joseph-Nathan, Rosalinda Contreras

Journal:

Year:

1990

Language:

english

File:

PDF, 651 KB

english, 1990

21

Effects of high-dose fenfluramine treatment on monoamine uptake sites in rat brain: Assessment using quantitative autoradiography

Nathan M. Appel, Wm. Mark Mitchell, Joseph F. Contrera, Errol B. Desouza

Journal:

Year:

1990

Language:

english

File:

PDF, 4.16 MB

english, 1990

22

A review of the in vitro and in vivo neurochemical characterization of the NMDA/PCP/Glycine/Ion channel receptor macrocomplex

Paul L. Wood, Tadimeti S. Rao, Smriti Iyengar, Thomas Lanthorn, Joseph Monahan, Alex Cordi, Eric Sun, Michael Vazquez, Nancy Gray, Patricia Contreras

Journal:

Neurochemical Research

Year:

1990

Language:

english

File:

PDF, 1.39 MB

english, 1990

23

Preparation and characterization of new transition metal complexes of nitroimidazoles. X-Ray crystal structures of two copper complexes: bis-[(μ-chloro)chloro-bis-(1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole)copper(II)] and dichloro-bis-(2-methyl-s-nitroimidazole)copper(II). First observation of nitro group coordination to the metal ion in these heterocycles

Norah Barba-Behrens, Ana María Mutio-Rico, Pedro Joseph-Nathan, Rosalinda Contreras

Journal:

Year:

1991

Language:

english

File:

PDF, 769 KB

english, 1991

24

Contrasting Neurochemical Interactions of Tiletamine, a Potent Phencyclidine (PCP) Receptor Ligand, with the N-Methyl-D-Aspartate-Coupled and -Uncoupled PCP Recognition Sites

Tadimeti S. Rao, Patricia C. Contreras, Julie A. Cler, Steve J. Mick, Vickie M. Dilworth, Smriti Iyengar, Joseph B. Monahan, Paul L. Wood

Journal:

Journal of Neurochemistry

Year:

1991

Language:

english

File:

PDF, 822 KB

english, 1991

25

The Amphibian Melanization Inhibiting Factor (MIF) Blocks the α-MSH Effect on Mouse Malignant Melanocytes

ANA M. LÓPEZ-CONTRERAS, JOSÉ H. MARTÍNEZ-LIARTE, FRANCISCO SOLANO, PREMINDA SAMARAWEERA, J.M. NEWTON, JOSEPH T. BAGNARA

Journal:

Pigment Cell & Melanoma Research

Year:

1996

Language:

english

File:

PDF, 694 KB

english, 1996

26

Preparation, X-ray crystal structure and 13C- and 1H-NMR study of 1-methyl-2-(N-methyl-N-phenylglycyl)-3-(N-methylanilino)indole

Norberto Farfán, J. Manuel Hernández, Pedro Joseph-Nathan, Rosalinda Contreras

Journal:

Journal of Heterocyclic Chemistry

Year:

1990

File:

PDF, 268 KB

1990

27

Phencyclidine

Patricia C. Contreras, Joseph B. Monahan, Thomas H. Lanthorn, Linda M. Pullan, Debora A. DiMaggio, Gail E. Handelmann, Nancy M. Gray, Thomas L. O’Donohue

Journal:

Molecular Neurobiology

Year:

1987

Language:

english

File:

PDF, 2.37 MB

english, 1987

28

Methylphenidate and pemoline do not cause depletion of rat brain monoamine markers similar to that observed with methamphetamine

Robert Zaczek, George Battaglia, Joseph F. Contrera, Steven Culp, Errol B. De Souza

Journal:

Toxicology and Applied Pharmacology

Year:

1989

Language:

english

File:

PDF, 663 KB

english, 1989

29

Comparison of the effects of repeated oral versus subcutaneous fenfluramine administration on rat brain monoamine neurons: Pharmacokinetic and dose-response data

Errol B. De Souza, Robert Zaczek, Steven Culp, Nathan M. Appel, Joseph F. Contrera

Journal:

Pharmacology Biochemistry and Behavior

Year:

1991

Language:

english

File:

PDF, 748 KB

english, 1991

30

Progress in QSAR toxicity screening of pharmaceutical impurities and other FDA regulated products

Naomi L. Kruhlak, Joseph F. Contrera, R. Daniel Benz, Edwin J. Matthews

Journal:

Advanced Drug Delivery Reviews

Year:

2007

Language:

english

File:

PDF, 514 KB

english, 2007

31

Effects of dehydroepiandrosterone on proliferation, migration, and death of breast cancer cells

Rebeca López-Marure, Piedad Gómez Contreras, Joseph S. Dillon

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

32

Prediction of rodent carcinogenic potential of naturally occurring chemicals in the human diet using high-throughput QSAR predictive modeling

Luis G. Valerio Jr., Kirk B. Arvidson, Ronald F. Chanderbhan, Joseph F. Contrera

Journal:

Toxicology and Applied Pharmacology

Year:

2007

Language:

english

File:

PDF, 280 KB

english, 2007

33

An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: I. Identification of carcinogens using surrogate endpoints

Edwin J. Matthews, Naomi L. Kruhlak, Michael C. Cimino, R. Daniel Benz, Joseph F. Contrera

Journal:

Regulatory Toxicology and Pharmacology

Year:

2006

Language:

english

File:

PDF, 624 KB

english, 2006

34

An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: II. Identification of genotoxicants, reprotoxicants, and carcinogens using in silico methods

Edwin J. Matthews, Naomi L. Kruhlak, Michael C. Cimino, R. Daniel Benz, Joseph F. Contrera

Journal:

Regulatory Toxicology and Pharmacology

Year:

2006

Language:

english

File:

PDF, 539 KB

english, 2006

35

A comprehensive model for reproductive and developmental toxicity hazard identification: II. Construction of QSAR models to predict activities of untested chemicals

Edwin J. Matthews, Naomi L. Kruhlak, R. Daniel Benz, Julian Ivanov, Gilles Klopman, Joseph F. Contrera

Journal:

Regulatory Toxicology and Pharmacology

Year:

2007

Language:

english

File:

PDF, 268 KB

english, 2007

36

Comparison of MC4PC and MDL-QSAR rodent carcinogenicity predictions and the enhancement of predictive performance by combining QSAR models

Joseph F. Contrera, Naomi L. Kruhlak, Edwin J. Matthews, R. Daniel Benz

Journal:

Regulatory Toxicology and Pharmacology

Year:

2007

Language:

english

File:

PDF, 880 KB

english, 2007

37

A comprehensive model for reproductive and developmental toxicity hazard identification: I. Development of a weight of evidence QSAR database

Edwin J. Matthews, Naomi L. Kruhlak, R. Daniel Benz, Joseph F. Contrera

Journal:

Regulatory Toxicology and Pharmacology

Year:

2007

Language:

english

File:

PDF, 242 KB

english, 2007

38

Identification of structure–activity relationships for adverse effects of pharmaceuticals in humans. Part A: Use of FDA post-market reports to create a database of hepatobiliary and urinary tract toxicities

Carling J. Ursem, Naomi L. Kruhlak, Joseph F. Contrera, Philip M. MacLaughlin, R. Daniel Benz, Edwin J. Matthews

Journal:

Regulatory Toxicology and Pharmacology

Year:

2009

Language:

english

File:

PDF, 315 KB

english, 2009

39

Identification of structure–activity relationships for adverse effects of pharmaceuticals in humans: Part C: Use of QSAR and an expert system for the estimation of the mechanism of action of drug-induced hepatobiliary and urinary tract toxicities

Edwin J. Matthews, Naomi L. Kruhlak, R. Daniel Benz, David Aragonés Sabaté, Carol A. Marchant, Joseph F. Contrera

Journal:

Regulatory Toxicology and Pharmacology

Year:

2009

Language:

english

File:

PDF, 354 KB

english, 2009

40

Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans: Part B. Use of (Q)SAR systems for early detection of drug-induced hepatobiliary and urinary tract toxicities

Edwin J. Matthews, Carling J. Ursem, Naomi L. Kruhlak, R. Daniel Benz, David Aragonés Sabaté, Chihae Yang, Gilles Klopman, Joseph F. Contrera

Journal:

Regulatory Toxicology and Pharmacology

Year:

2009

Language:

english

File:

PDF, 293 KB

english, 2009

41

Improved in silico prediction of carcinogenic potency (TD50) and the risk specific dose (RSD) adjusted Threshold of Toxicological Concern (TTC) for genotoxic chemicals and pharmaceutical impurities

Joseph F. Contrera

Journal:

Regulatory Toxicology and Pharmacology

Year:

2011

Language:

english

File:

PDF, 261 KB

english, 2011

42

Insulin-like growth factor-I prevents development of a vincristine neuropathy in mice

Patricia C Contreras, Jeffry L Vaught, John A Gruner, Celia Brosnan, Cathy Steffler, Joseph C Arezzo, Michael E Lewis, John A Kessler, Stuart C Apfel

Journal:

Year:

1997

Language:

english

File:

PDF, 444 KB

english, 1997

43

Does social environment decrease propensity to fight in male mice?

J.N. Crawley, Wolfgang M. Schleidt, Joseph F. Contrera

Journal:

Behavioral Biology

Year:

1975

Language:

english

File:

PDF, 1.93 MB

english, 1975

44

A multicenter, prospective, randomized, comparative evaluation of dual- versus triple-lumen catheters for hemodialysis and apheresis in 485 patients

Gabriel Contreras, Ping-Yu Liu, Lawrence Elzinga, Michael S Anger, Jean Lee, Nurian Robert, Robert Chvala, Ronald L Mars, Thomas Vesely, Tim E Taber, Douglas Shemin, Randy Shafritz, Joseph Pulliam

Journal:

American Journal of Kidney Diseases

Year:

2003

Language:

english

File:

PDF, 106 KB

english, 2003

45

Plasma and Urinary Levels of Erythropoietin in Cooley's Anemia

Albert S. Gordon, Arthur H. Weintraub, James F. Camiscoli, Joseph F. Contrera

Journal:

Annals of the New York Academy of Sciences

Year:

1964

Language:

english

File:

PDF, 788 KB

english, 1964

46

THE RENAL ERYTHROPOIETIC FACTOR. I. STUDIES ON ITS PURIFICATION AND PROPERTIES

Joseph F. Contrera, Albert S. Gordon

Journal:

Annals of the New York Academy of Sciences

Year:

1968

Language:

english

File:

PDF, 326 KB

english, 1968

47

Carcinogenicity Testing and the Evaluation of Regulatory Requirements for Pharmaceuticals

Joseph F Contrera, Abigail C Jacobs, Joseph J DeGeorge

Journal:

Regulatory Toxicology and Pharmacology

Year:

1997

Language:

english

File:

PDF, 144 KB

english, 1997

48

A New Highly Specific Method for Predicting the Carcinogenic Potential of Pharmaceuticals in Rodents Using EnhancedMCASEQSAR-ES Software

Edwin J. Matthews, Joseph F. Contrera

Journal:

Regulatory Toxicology and Pharmacology

Year:

1998

Language:

english

File:

PDF, 179 KB

english, 1998

49

Cobalt-induced alterations in plasma proteins, proteases and kinin system of the rat

Robert J. Smith, Joseph F. Contrera

Journal:

Biochemical Pharmacology

Year:

1974

Language:

english

File:

PDF, 662 KB

english, 1974

50

Glycine modulation of the phencyclidine binding site in mammalian brain

John W. Thomas, William F. Hood, Joseph B. Monahan, Patricia C. Contreras, Thomas L. O'Donohue

Journal:

Year:

1988

Language:

english

File:

PDF, 274 KB

english, 1988