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51

DNA-Binding Activity of Adeno-Associated Virus Rep Is Required for Inverted Terminal Repeat-Dependent Complex Formation with Herpes Simplex Virus ICP8

Alex, M., Weger, S., Mietzsch, M., Slanina, H., Cathomen, T., Heilbronn, R.

Journal:

Journal of Virology

Year:

2012

Language:

english

File:

PDF, 933 KB

english, 2012

52

Genome Editing Technologies: Defining a Path to Clinic

Corrigan-Curay, Jacqueline, O'Reilly, Marina, Kohn, Donald B, Cannon, Paula M, Bao, Gang, Bushman, Frederic D, Carroll, Dana, Cathomen, Toni, Joung, J Keith, Roth, David, Sadelain, Michel, Scharenberg

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 636 KB

english, 2015

53

Influence of N-linked oligosaccharide chains on the processing, cell surface expression and function of the measles virus fusion protein

Hu, A., Cathomen, T., Cattaneo, R., Norrby, E.

Journal:

Journal of General Virology

Year:

1995

Language:

english

File:

PDF, 3.32 MB

english, 1995

54

Expanding or Restricting the Target Site Repertoire of Zinc-finger Nucleases: The Inter-domain Linker as a Major Determinant of Target Site Selectivity

Händel, Eva-Maria, Alwin, Stephen, Cathomen, Toni

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 986 KB

english, 2009

55

Impaired Axonal Transport in Motor Neurons Correlates with Clinical Prion Disease

Ermolayev, Vladimir, Cathomen, Toni, Merk, Julia, Friedrich, Mike, Härtig, Wolfgang, Harms, Gregory S., Klein, Michael A., Flechsig, Eckhard, Agrimi, Umberto

Journal:

Year:

2009

Language:

english

File:

PDF, 735 KB

english, 2009

56

Integration Preferences of Wildtype AAV-2 for Consensus Rep-Binding Sites at Numerous Loci in the Human Genome

Hüser, Daniela, Gogol-Döring, Andreas, Lutter, Timo, Weger, Stefan, Winter, Kerstin, Hammer, Eva-Maria, Cathomen, Toni, Reinert, Knut, Heilbronn, Regine, Cullen, Bryan R.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.74 MB

english, 2010

57

Hemoglobin mass and intravascular volume kinetics during and after exposure to 3,454 m altitude

Siebenmann, Christoph, Cathomen, Adrian, Hug, Mike, Keiser, Stefanie, Lundby, Anne-Kristine Meinild, Hilty, Matthias Peter, Goetze, Jens Peter, Rasmussen, Peter, Lundby, Carsten

Journal:

Journal of Applied Physiology

Year:

2015

Language:

english

File:

PDF, 336 KB

english, 2015

58

Cerebrovascular reactivity is increased with acclimatization to 3,454 m altitude

Flück, Daniela, Siebenmann, Christoph, Keiser, Stefanie, Cathomen, Adrian, Lundby, Carsten

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2015

Language:

english

File:

PDF, 985 KB

english, 2015

59

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases

Mock, Ulrike, Riecken, Kristoffer, Berdien, Belinda, Qasim, Waseem, Chan, Emma, Cathomen, Toni, Fehse, Boris

Journal:

Scientific Reports

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

60

TALEN-mediated functional correction of X-linked chronic granulomatous disease in patient-derived induced pluripotent stem cells

Dreyer, Anne-Kathrin, Hoffmann, Dirk, Lachmann, Nico, Ackermann, Mania, Steinemann, Doris, Timm, Barbara, Siler, Ulrich, Reichenbach, Janine, Grez, Manuel, Moritz, Thomas, Schambach, Axel, Cathomen, T

Journal:

Year:

2015

Language:

english

File:

PDF, 2.89 MB

english, 2015

61

Targeted Genome Modifications Using Integrase‐deficient Lentiviral Vectors

Cornu, Tatjana I, Cathomen, Toni

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 261 KB

english, 2007

62

Proven and novel strategies for efficient editing of the human genome

C. Mussolino, T. Mlambo, T. Cathomen

Year:

2015

Language:

english

File:

PDF, 871 KB

english, 2015

63

Enantioselective Construction of Indanones from Cyclobutanols Using a Rhodium-Catalyzed C-C/C-H/C-C Bond Activation Process

Seiser, Tobias, Cathomen, Gino, Cramer, Nicolai

Journal:

Year:

2010

Language:

english

File:

PDF, 118 KB

english, 2010

64

Zinc-finger Nuclease-induced Gene Repair With Oligodeoxynucleotides: Wanted and Unwanted Target Locus Modifications

Radecke, Sarah, Radecke, Frank, Cathomen, Toni, Schwarz, Klaus

Journal:

Molecular Therapy

Year:

2010

Language:

english

File:

PDF, 433 KB

english, 2010

65

DNA-binding Specificity Is a Major Determinant of the Activity and Toxicity of Zinc-finger Nucleases

Cornu, Tatjana I, Thibodeau-Beganny, Stacey, Guhl, Eva, Alwin, Stephen, Eichtinger, Magdalena, Joung, JK, Cathomen, Toni

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 270 KB

english, 2008

66

Histone Deacetylase Inhibition Rescues Gene Knockout Levels Achieved with Integrase-Defective Lentiviral Vectors Encoding Zinc-Finger Nucleases

Pelascini, Laetitia P.L., Maggio, Ignazio, Liu, Jin, Holkers, Maarten, Cathomen, Toni, Gonçalves, Manuel A.F.V.

Journal:

Human Gene Therapy Methods

Year:

2013

Language:

english

File:

PDF, 1.36 MB

english, 2013

67

Streptococcus thermophilus CRISPR-Cas9 systems enable specific editing of the human genome

Müller, Maximilian, Lee, Ciaran M., Gasiunas, Giedrius, Davis, Timothy H., Cradick, Thomas J., Siksnys, Virginijus, Bao, Gang, Cathomen, Toni, Mussolino, Claudio

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 1.20 MB

english, 2015

68

[Advances in Experimental Medicine and Biology] Genome Editing ||

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 6.55 MB

english, 2016

69

[Advances in Experimental Medicine and Biology] Genome Editing || Strategies to Determine Off-Target Effects of Engineered Nucleases

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 886 KB

english, 2016

70

[Advances in Experimental Medicine and Biology] Genome Editing || Engineered Nucleases and Trinucleotide Repeat Diseases

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 445 KB

english, 2016

71

[Advances in Experimental Medicine and Biology] Genome Editing || The Development and Use of Zinc-Finger Nucleases

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 309 KB

english, 2016

72

[Advances in Experimental Medicine and Biology] Genome Editing || Gene Editing 20 Years Later

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 295 KB

english, 2016

73

[Advances in Experimental Medicine and Biology] Genome Editing || Phage Integrases for Genome Editing

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 339 KB

english, 2016

74

[Advances in Experimental Medicine and Biology] Genome Editing || Using Engineered Nucleases to Create HIV-Resistant Cells

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 625 KB

english, 2016

75

[Advances in Experimental Medicine and Biology] Genome Editing || Cellular Engineering and Disease Modeling with Gene-Editing Nucleases

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 752 KB

english, 2016

76

[Advances in Experimental Medicine and Biology] Genome Editing || The Use and Development of TAL Effector Nucleases

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 517 KB

english, 2016

77

[IEEE Proceedings of HICSS-29: 29th Hawaii International Conference on System Sciences - Wailea, HI, USA (1996.01.3-1996.01.6)] Proceedings of HICSS-29: 29th Hawaii International Conference on System Sciences - The diffusion of FEDI in the United Kingdom and Switzerland: a comparative case study

Cathomen, I., Williams, H.

Year:

1996

Language:

english

File:

PDF, 797 KB

english, 1996

78

[Advances in Experimental Medicine and Biology] Genome Editing || Genome Editing by Aptamer-Guided Gene Targeting (AGT)

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 1.21 MB

english, 2016

79

[Advances in Experimental Medicine and Biology] Genome Editing || Genome Editing for Neuromuscular Diseases

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 479 KB

english, 2016

80

[Advances in Experimental Medicine and Biology] Genome Editing || Precise Genome Modification Using Triplex Forming Oligonucleotides and Peptide Nucleic Acids

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 534 KB

english, 2016

81

The Development of FEDI in Switzerland: A Life-Cycle Approach

Cathomen, Ivo, Klein, Stefan

Journal:

International Journal of Electronic Commerce

Year:

1997

Language:

english

File:

PDF, 1.44 MB

english, 1997

82

Targeted gene addition strategies for the treatment of X-linked lymphoproliferative disease

Houghton, Ben, Mussolino, Claudio, Cathomen, Toni, Gaspar, H Bobby, Booth, Claire

Journal:

Year:

2016

Language:

english

File:

PDF, 58 KB

english, 2016

83

Zinc-Finger Nuclease Based Genome Surgery: Its All About Specificity

Handel, Eva-Maria, Cathomen, Toni

Journal:

Current Gene Therapy

Year:

2011

Language:

english

File:

PDF, 846 KB

english, 2011

84

SNAI1 gene disruption in rhabdomyosarcoma cells using CRISPR/Cas9 and TALEN nucleases

Skrzypek, Klaudia, Ulman, Aleksandra, Szewczyk, Barbara, Mussolino, Claudio, Cathomen, Toni, Majka, Marcin

Journal:

New Biotechnology

Year:

2016

Language:

english

File:

PDF, 46 KB

english, 2016

85

Deciphering the impact of parameters influencing transgene expression kinetics after repeated cell transduction with integration-deficient retroviral vectors

Schott, Juliane W., Jaeschke, Nico M., Hoffmann, Dirk, Maetzig, Tobias, Ballmaier, Matthias, Godinho, Tamaryin, Cathomen, Toni, Schambach, Axel

Journal:

Cytometry Part A

Year:

2015

Language:

english

File:

PDF, 1.02 MB

english, 2015

86

Discoloration of the mucosa caused by different restorative materials - a spectrophotometric in vitro study

Ioannidis, Alexis, Cathomen, Elena, Jung, Ronald E., Fehmer, Vincent, Hüsler, Jürg, Thoma, Daniel S.

Journal:

Clinical Oral Implants Research

Year:

2016

Language:

english

File:

PDF, 416 KB

english, 2016

87

[Advances in Experimental Medicine and Biology] Genome Editing || Stimulation of AAV Gene Editing via DSB Repair

Cathomen, Toni, Hirsch, Matthew, Porteus, Matthew

Year:

2016

Language:

english

File:

PDF, 197 KB

english, 2016

88

Systems for Computer-Mediated Digital Commerce || The Development of FEDI in Switzerland: A Life-Cycle Approach

Ivo Cathomen and Stefan Klein

Journal:

International Journal of Electronic Commerce

Year:

1997

Language:

english

File:

PDF, 1.61 MB

english, 1997

89

Gene editing – From modeling diseases to treating patients

Journal:

Journal of Reproductive Immunology

Year:

2016

Language:

english

File:

PDF, 93 KB

english, 2016

90

LB795 TALEN-mediated elimination of mutant keratin 14 as a gene therapy for epidermolysis bullosa simplex

Aushev, M., Mussolino, C., Cathomen, T., Reichelt, J.

Journal:

The Journal of Investigative Dermatology

Year:

2016

Language:

english

File:

PDF, 50 KB

english, 2016

91

692. Genome Editing for Personalized Gene Therapy of IVSI-110 Beta-Thalassemia

Patsali, Petros, Mussolino, Claudio, Loucari, Constantinos, Stephanou, Coralea, Antoniou, Michael, Cathomen, Toni, Lederer, Carsten W., Kleanthous, Marina

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 300 KB

english, 2016

92

325. Targeted Gene Addition Strategies for the Treatment of X-Linked Lymphoproliferative Disease

Houghton, Benjamin C., Mussolino, Claudio, Cathomen, Toni, Gaspar, H Bobby, Booth, Claire

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 378 KB

english, 2016

93

118. Inhibition of Hepatitis B Virus Replication In Vivo Following Delivery of Antiviral TALENs With Recombinant Adeno-Associated Viral Vectors

Nicholson, Samantha, Moyo, Buhle, Bloom, Kristie, Mussolino, Claudio, Cathomen, Toni, Watashi, Koichi, Ely, Abdullah, Arbuthnot, Patrick

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 297 KB

english, 2015

94

483. Epigenetic Silencing of Hepatitis B cccDNA In Vitro and In Vivo Using AAV-Delivered Engineered Repressor Transcription Activator-Like Effector

Moyo, Buhle, Nicholson, Samantha, Roelofse, Ilke, Crowther, Carol, Bloom, Kristie, Mussolino, Claudio, Cathomen, Toni, Watashi, Koichi, Ely, Abdullah, Arbuthnot, Patrick

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 302 KB

english, 2015

95

Genom-Editierung — neue Wege im klinischen Alltag

Viviane Dettmer,Toni Cathomen,Markus Hildenbeutel

Journal:

Year:

2017

Language:

german

File:

PDF, 610 KB

german, 2017

96

Traceless Targeting and Isolation of Gene-Edited Immortalized Keratinocytes from Epidermolysis Bullosa Simplex Patients

Aushev, Magomet, Koller, Ulrich, Mussolino, Claudio, Cathomen, Toni, Reichelt, Julia

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2017

Language:

english

File:

PDF, 617 KB

english, 2017

97

Generation of a gene-corrected isogenic control iPSC line from cystic fibrosis patient-specific iPSCs homozygous for p.Phe508del mutation mediated by TALENs and ssODN

Merkert, Sylvia, Bednarski, Christien, Göhring, Gudrun, Cathomen, Toni, Martin, Ulrich

Journal:

Stem Cell Research

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

98

Gene Repair: Pointing the finger at genetic disease

Cathomen, T, Weitzman, M D

Journal:

Year:

2005

Language:

english

File:

PDF, 90 KB

english, 2005

99

Genome and epigenome editing to treat disorders of the hematopoietic system

Mussolino, Claudio, Alzubi, Jamal, Pennucci, Valentina, Turchiano, Giandomenico, Cathomen, Toni

Journal:

Human Gene Therapy

Year:

2017

Language:

english

File:

PDF, 401 KB

english, 2017

100

Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model

Alzubi, Jamal, Pallant, Celeste, Mussolino, Claudio, Howe, Steven J., Thrasher, Adrian J., Cathomen, Toni

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.44 MB

english, 2017