Chêne, Patrick: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Inhibiting the p53–MDM2 interaction: an important target for cancer therapy

Chène, Patrick

Journal:

Nature Reviews Cancer

Year:

2003

Language:

english

File:

PDF, 1.08 MB

english, 2003

2

Potentiality of front-face fluorescence and mid-infrared spectroscopies coupled with partial least square regression to predict lipid oxidation in pound cakes during storage

Nhouchi, Zeineb, Botosoa, Eliot Patrick, Chene, Christine, Karoui, Romdhane

Journal:

Year:

2019

Language:

english

File:

PDF, 761 KB

english, 2019

3

Aib-based peptide backbone as scaffolds for helical peptide mimics

Raja Banerjee, Gautam Basu, Siddhartha Roy, Patrick Chène

Journal:

Chemical Biology & Drug Design

Year:

2002

Language:

english

File:

PDF, 162 KB

english, 2002

4

The TEAD4-YAP/TAZ Protein-Protein Interaction: Expected Similarities and Unexpected Differences

Hau, Jean Christophe, Erdmann, Dirk, Mesrouze, Yannick, Furet, Pascal, Fontana, Patrizia, Zimmermann, Catherine, Schmelzle, Tobias, Hofmann, Francesco, Chène, Patrick

Journal:

Year:

2013

Language:

english

File:

PDF, 990 KB

english, 2013

5

Characterization of p53 mutants identified in human tumors with a missense mutation in the tetramerization domain

Christiane Rollenhagen, Patrick Chène

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 127 KB

english, 1998

6

Functional analyses of a unique p53 germline mutant (y236Δ) associated with a familial brain tumor syndrome

Patrick Chène, Katherine Ory, Daniela Rüedi, Thierry Soussi, Monika E. Hegi

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 112 KB

english, 1999

7

Oligomerisierung von p53 nach kooperativer Bindung an DNA: ein Beitrag zum strukturellen Verständnis der Funktion von p53

Patrick Chene, Wolfgang Jahnke

Journal:

Angewandte Chemie

Year:

2002

Language:

german

File:

PDF, 94 KB

german, 2002

8

Oligomerization of p53 upon Cooperative DNA Binding: Towards a Structural Understanding of p53 Function

Patrick Chene, Wolfgang Jahnke

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 92 KB

english, 2002

9

ChemInform Abstract: Oligomerization of p53 upon Cooperative DNA Binding: Towards a Structural Understanding of p53 Function

Patrick Chene, Wolfgang Jahnke

Journal:

Year:

2002

File:

PDF, 25 KB

2002

10

Microtubule assembly protects the region 28–38 of the β- tubulin subunit

Patrick Chène, Honoré Mazarguiland, Michel Wright

Journal:

Year:

1992

Language:

english

File:

PDF, 1.15 MB

english, 1992

11

Drugs Targeting Protein–Protein Interactions

Journal:

Year:

2006

Language:

english

File:

PDF, 768 KB

english, 2006

12

Can highly active antiretroviral therapy be interrupted in patients with sustained moderate HIV RNA and > 400 CD4+ cells/µl? Impact on immunovirological parameters

Isabelle Pellegrin, Rodolphe Thiébaut, Patrick Blanco, Jean-François Viallard, Marie-Hélène Schrive, Patrick Merel, Geneviève Chêne, Hervé Fleury, Jean-François Moreau, Jean-Luc Pellegrin

Journal:

Journal of Medical Virology

Year:

2005

Language:

english

File:

PDF, 188 KB

english, 2005

13

Neutralizing antibodies to interferon-α and circulating interferon in patients with chronic hepatitis C non-responding to pegylated interferon plus ribavirin re-treated by pegylated interferon-α-2a and ribavirin (ANRS HC16 GAMMATRI substudy*)

Philippe Halfon, Sophie Pérusat, Marc Bourlière, Jean-Pierre Bronowicki, Pascale Trimoulet, Yves Benhamou, Vincent Leroy, Patrick Marcellin, Juliette Foucher, Guillaume Penaranda, Geneviève Chêne, Pat

Journal:

Journal of Medical Virology

Year:

2010

Language:

english

File:

PDF, 71 KB

english, 2010

14

Inhibition of DNA helicases with DNA-competitive inhibitors

Sandy Dubaele, Wolfang Jahnke, Joseph Schoepfer, Jean Fuchs, Patrick Chène

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 174 KB

english, 2006

15

“4D Biology for health and disease” workshop report

Jan-Pieter Abrahams, Rolf Apweiler, Rudi Balling, Michela G. Bertero, Janusz M. Bujnicki, Naomi E. Chayen, Patrick Chène, Gary L. Corthals, Tomasz Dyląg, Friedrich Förster, Albert J.R. Heck, Peter J.F

Journal:

New Biotechnology

Year:

2011

Language:

english

File:

PDF, 94 KB

english, 2011

16

Discovery of a new class of catalytic topoisomerase II inhibitors targeting the ATP-binding site by structure based design. Part I

Pascal Furet, Joseph Schoepfer, Thomas Radimerski, Patrick Chène

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 965 KB

english, 2009

17

2-Amino-aryl-7-aryl-benzoxazoles as potent, selective and orally available JAK2 inhibitors

Marc Gerspacher, Pascal Furet, Carole Pissot-Soldermann, Christoph Gaul, Philipp Holzer, Eric Vangrevelinghe, Marc Lang, Dirk Erdmann, Thomas Radimerski, Catherine H. Regnier, Patrick Chene, Alain De

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.56 MB

english, 2010

18

Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein–protein interaction

Carlos Garcı́a-Echeverrı́a, Pascal Furet, Patrick Chène

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 117 KB

english, 2001

19

Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue

Patrick Chène, Joëlle Rudloff, Joseph Schoepfer, Pascal Furet, Peter Meier, Zhiyan Qian, Jean-Marc Schlaeppi, Rita Schmitz, Thomas Radimerski

Journal:

BMC Chemical Biology

Year:

2009

Language:

english

File:

PDF, 2.36 MB

english, 2009

20

ATPases as drug targets: learning from their structure

Chène, Patrick

Journal:

Nature Reviews Drug Discovery

Year:

2002

Language:

english

File:

PDF, 743 KB

english, 2002

21

The role of tetramerization in p53 function

Chène, Patrick

Journal:

Year:

2001

Language:

english

File:

PDF, 248 KB

english, 2001

22

Phylogenetic implications of the structure-function relationships of tubulin

Patrick Chene, Honore Mazarguil, Pierre Rouge

Journal:

Biochemical Systematics and Ecology

Year:

1992

Language:

english

File:

PDF, 574 KB

english, 1992

23

The central valine concept provides an entry in a new class of non peptide inhibitors of the p53–MDM2 interaction

Pascal Furet, Patrick Chène, Alain De Pover, Thérèse Stachyra Valat, Joanna Hergovich Lisztwan, Joerg Kallen, Keiichi Masuya

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

24

PcrA/UvrD/Rep DNA helicases in bacterial genomes

Journal:

Biochemical Systematics and Ecology

Year:

2008

Language:

english

File:

PDF, 216 KB

english, 2008

25

Challenges in design of biochemical assays for the identification of small molecules to target multiple conformations of protein kinases

Journal:

Drug Discovery Today

Year:

2008

Language:

english

File:

PDF, 445 KB

english, 2008

26

Can biochemistry drive drug discovery beyond simple potency measurements?

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 376 KB

english, 2012

27

Role of Isoleucine-164 at the Active Site of Rubisco fromRhodospirillum rubrum

Patrick Chène, Anthony G. Day, Alan R. Fersht

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 109 KB

english, 1997

28

Mutations at Position 277 Modify the DNA-Binding Specificity of Human p53 in Vitro

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 138 KB

english, 1999

29

Molecular characterization of the hdm2-p53 interaction

Angelika Böttger, Volker Böttger, Carlos Garcia-Echeverria, Patrick Chène, Heinz-Kurt Hochkeppel, Wayne Sampson, Kiah Ang, Stephanie F. Howard, Steven M. Picksley, David P. Lane

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 497 KB

english, 1997

30

In vitro structure-function analysis of the β-strand 326-333 of human p53

Patrick Chène, Peer Mittl, Markus Grütter

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 460 KB

english, 1997

31

P53 mutants without a functional tetramerisation domain are not oncogenic

Patrick Chène, Elisabeth Bechter

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 263 KB

english, 1999

32

Influence of the N-terminal region on the oligomerisation between human and Xenopus laevis p53

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 706 KB

english, 1999

33

Cellular characterisation of p53 mutants with a single missense mutation in the β-strand 326–333 and correlation of their cellular activities with in vitro properties

Patrick Chène, Elisabeth Bechter

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 319 KB

english, 1999

34

A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines

Patrick Chène, Jean Fuchs, Jacqueline Bohn, Carlos Garcı́a-Echeverrı́a, Pascal Furet, Doriano Fabbro

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 286 KB

english, 2000

35

Preferential localization of a protein methylating-demethylating system in proximal tubules of rat kidney

Luc Chéné, Lucie Bourget, Patrick Vinay, Claude Gagnon

Journal:

Archives of Biochemistry and Biophysics

Year:

1982

Language:

english

File:

PDF, 624 KB

english, 1982

36

Mutation of asparagine 111 of rubisco from Rhodospirillum rubrum alters the carboxylase/oxygenase specificity

Patrick Chène, Anthony G. Day, Alan R. Fersht

Journal:

Journal of Molecular Biology

Year:

1992

Language:

english

File:

PDF, 835 KB

english, 1992

37

Glucose effect on the expression of 150 kDa oxygen-regulated protein in HeLa cells

Marzanna Cechowska-Pasko, Edward Bańkowski, Patrick Chene

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 267 KB

english, 2005

38

Study of the ATP-binding site of helicase IV from Escherichia coli

Sandy Dubaele, Claude Lourdel, Patrick Chène

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 745 KB

english, 2006

39

Investigation of alkali borosilicate glass durability using tritium tracing, β-autoradiography, scanning electron microscopy and ion beam analysis

Jacques Chêne, Patrick Trocellier

Journal:

Journal of Non-Crystalline Solids

Year:

2004

Language:

english

File:

PDF, 798 KB

english, 2004

40

Study of the cytotoxic effect of a peptidic inhibitor of the p53–hdm2 interaction in tumor cells

Patrick Chène, Jean Fuchs, Ilaria Carena, Pascal Furet, Carlos Garcı́a Echeverrı́a

Journal:

Year:

2002

Language:

english

File:

PDF, 227 KB

english, 2002

41

Mutation of threonine-53 alters the kinetic properties of rubisco from Rhodospirillum rubrum

Patrick Chène, Christiane Chène

Journal:

Journal of Plant Physiology

Year:

1998

Language:

english

File:

PDF, 484 KB

english, 1998

42

The gain of function of the p53 mutant Asp281Gly is dependent on its ability to form tetramers

Annemieke Atema, Patrick Chène

Journal:

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

43

TT virus infection during chronic hepatitis C

Pascale Trimoulet, Victor de Lédinghen, Didier Ekouevi, Pierre-Henri Bernard, Patrick Merel, Geneviève Chêne, Patrice Couzigou, Hervé Fleury

Journal:

American Journal of Gastroenterology

Year:

2000

Language:

english

File:

PDF, 49 KB

english, 2000

44

Interferon-gamma with peginterferon alpha-2a and ribavirin in nonresponder patients with chronic hepatitis C (ANRS HC16 GAMMATRI)

Couzigou, Patrice, Pérusat, Sophie, Bourlière, Marc, Trimoulet, Pascale, Poynard, Thierry, Leroy, Vincent, Marcellin, Patrick, Foucher, Juliette, Bronowicki, Jean-Pierre, Chêne, Geneviève

Journal:

Journal of Gastroenterology and Hepatology

Year:

2013

Language:

english

File:

PDF, 385 KB

english, 2013

45

Monitoring Changes in Sponge Cakes during Aging by Front Face Fluorescence Spectroscopy and Instrumental Techniques

Botosoa, Eliot Patrick, Chénè, Christine, Karoui, Romdhane

Journal:

Journal of Agricultural and Food Chemistry

Year:

2013

Language:

english

File:

PDF, 593 KB

english, 2013

46

Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3- d ]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone

Brough, Paul A., Barril, Xavier, Borgognoni, Jenifer, Chene, Patrick, Davies, Nicholas G. M., Davis, Ben, Drysdale, Martin J., Dymock, Brian, Eccles, Suzanne A., Garcia-Echeverria, Carlos, Fromont, Ch

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 4.07 MB

english, 2009

47

Factors influencing the inhibition of protein kinases

Brockhoff, Marielle, Hau, Jean-Christophe, Fontana, Patrizia, Zimmermann, Catherine, De Pover, Alain, Erdmann, Dirk, Chène, Patrick

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 842 KB

english, 2012

48

Use of front face fluorescence for monitoring lipid oxidation during ageing of cakes

Botosoa, Eliot Patrick, Chèné, Christine, Karoui, Romdhane

Journal:

Year:

2013

Language:

english

File:

PDF, 662 KB

english, 2013

49

The Surprising Features of the TEAD4-Vgll1 Protein-Protein Interaction

Mesrouze, Yannick, Hau, Jean Christophe, Erdmann, Dirk, Zimmermann, Catherine, Fontana, Patrizia, Schmelzle, Tobias, Chène, Patrick

Journal:

Year:

2014

Language:

english

File:

PDF, 656 KB

english, 2014

50

Dual Specificity of Src Homology 2 Domains for Phosphotyrosine Peptide Ligands

Gay, Brigitte, Furet, Pascal, García-Echeverría, Carlos, Rahuel, Joseph, Chêne, Patrick, Fretz, Heinz, Schoepfer, Joseph, Caravatti, Giorgio

Journal:

Year:

1997

Language:

english

File:

PDF, 142 KB

english, 1997