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51

Cordycepin analogs of 2',5'-oligoadenylate inhibit human immunodeficiency virus infection via inhibition of reverse transcriptase

Mueller, Werner E. G., Weiler, Barbara E., Charubala, Ramamurthy, Pfleiderer, Wolfgang, Leserman, Lee, Sobol, Robert W., Suhadolnik, Robert J., Schroeder, Heinz C.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.77 MB

english, 1991

52

2′,5′-Adenylate and Cordycepin Trimer Cores: Metabolic Stability and Evidence for Antimitogenesis without 5′-Rephosphorylation

Suhadolnik, Robert J., Doetsch, Paul W., Devash, Yair, Henderson, Earl E., Charubala, Ramamurthy, Pfleiderer, Wolfgang

Journal:

Nucleosides and Nucleotides

Year:

1983

Language:

english

File:

PDF, 792 KB

english, 1983

53

New Photolabile Protecting Groups in Nucleoside and Nucleotide Chemistry—Synthesis, Cleavage Mechanisms and Applications

Giegrich, H., Eisele-Bühler, S., Hermann, Chr, Kvasyuk, E., Charubala, R., Pfleiderer, W.

Journal:

Nucleosides and Nucleotides

Year:

1998

Language:

english

File:

PDF, 408 KB

english, 1998

54

Structural and Functional Features of the 37-kDa 2-5A-Dependent RNase L in Chronic Fatigue Syndrome

Shetzline, Susan E., Martinand-Mari, Camille, Reichenbach, Nancy L., Buletic, Zivjena, Lebleu, Bernard, Pfleiderer, Wolfgang, Charubala, Ramamurthy, De Meirleir, Kenny, De Becker, Pascale, Peterson, D

Journal:

Journal of Interferon & Cytokine Research

Year:

2002

Language:

english

File:

PDF, 484 KB

english, 2002

55

[Part 2: Biological Sciences] || Core (2′-5′)oligoadenylate and the Cordycepin Analog: Inhibitors of Epstein--Barr Virus-Induced Transformation of Human Lymphocytes in the Absence of Interferon

Paul W. Doetsch, Robert J. Suhadolnik, Yosuke Sawada, Joseph D. Mosca, Maryann B. Flick, Nancy L. Reichenbach, An Quoc Dang, Joseph M. Wu, Ramamurthy Charubala, Wolfgang Pfleiderer and Earl E. Henders

Journal:

Proceedings of the National Academy of Sciences

Year:

1981

Language:

english

File:

PDF, 892 KB

english, 1981

56

Phosphorothioate and Cordycepin Analogues of 2′,5′-oligoadenylate: Inhibition of Human Immunodeficiency Virus Type 1 Reverse Transcriptase and Infection in vitro

David C. Montefiori, Robert W. Sobol, Shi Wu Li, Nancy L. Reichenbach, Robert J. Suhadolnik, Ramamurthy Charubala, Wolfgang Pfleiderer, Ann Modliszewski, W. Edward Robinson and William M. Mitchell

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 744 KB

english, 1989

57

Phosphorothioate analogs of 2',5'-oligoadenylate. Enzymatically synthesized 2',5'-phosphorothioate dimer and trimer: unequivocal structural assignment and activation of 2',5'-oligoadenylate-dependent endoribonuclease

Kariko, Katalin, Sobol, Robert W., Suhadolnik, Lorraine, Li, Shi Wu, Reichenbach, Nancy Lee, Suhadolnik, Robert J., Charubala, Ramamurthy, Pfleiderer, Wolfgang

Journal:

Year:

1987

Language:

english

File:

PDF, 1.65 MB

english, 1987

58

Phosphorothioate analogs of 2',5'-oligoadenylate. Activation of 2',5'-oligoadenylate-dependent endoribonuclease by 2',5'-phosphorothioate cores and 5'-monophosphates

Kariko, Katalin, Li, Shi Wu, Sobol, Robert W., Suhadolnik, Robert J., Charubala, Ramamurthy, Pfleiderer, Wolfgang

Journal:

Year:

1987

Language:

english

File:

PDF, 1.86 MB

english, 1987

59

The synthesis of a proerythrinadienone system by phenol oxidation

Kametani, T., Charubala, R., Ihara, M., Koizumi, M., Fukumoto, K.

Journal:

Journal of the Chemical Society D Chemical Communications

Year:

1971

Language:

english

File:

PDF, 153 KB

english, 1971

60

An approach to the synthesis of sinomenine

Kametani, T., Sugahara, T., Yagi, H., Fukumoto, K., Pai, B. R., Charubala, R.

Journal:

Journal of the Chemical Society C Organic

Year:

1970

Language:

english

File:

PDF, 348 KB

english, 1970

61

Inhibition of HIV Type 1 Replication in CD4 + and CD14 + Cells Purified from HIV Type 1-Infected Individuals by the 2-5A Agonist Immunomodulator, 2-5A N6B

Dimitrova, Dessislava I., Reichenbach, Nancy L., Yang, Xiaowei, Pfleiderer, Wolfgang, Charubala, Ramamurthy, Gaughan, John P., Suh, Byungse, Henderson, Earl E., Suhadolnik, Robert J., Rogers, Thomas J

Journal:

AIDS Research and Human Retroviruses

Year:

2007

Language:

english

File:

PDF, 873 KB

english, 2007

62

Synthesis of 3′-Deoxyadenylate Trimer

Himmelsbach, F., Uhlmann, E., Charubala, R., Pfleiderer, W.

Journal:

Nucleosides and Nucleotides

Year:

1985

Language:

english

File:

PDF, 172 KB

english, 1985

63

Synthesis of P-Thioadenylyl (2′-5′) Adenosine and P-Thioadenylyl (2′-5′)-P-Thioadenylyl-(2′-5′)-Adenosine

Charubala, R., Pfleiderer, W.

Journal:

Nucleosides and Nucleotides

Year:

1987

Language:

english

File:

PDF, 157 KB

english, 1987

64

Recent Progress in Oligoribonucleotide Synthesis

Pfister, Magdalena, Farkas, Silke, Charubala, Ramamurthy, Pfleiderer, Wolfgang

Journal:

Nucleosides and Nucleotides

Year:

1988

Language:

english

File:

PDF, 220 KB

english, 1988

65

Cordycepin Analogs of 2–5 a as Activators of RNase L: Study of the Structural Requirements for RNase L Activation

Kariko, Katalin, Reichenbach, Nancy L., Suhadolnik, Robert J., Charubala, Ramamurthy, Pfleiderer, Wolfgang

Journal:

Nucleosides and Nucleotides

Year:

1987

Language:

english

File:

PDF, 212 KB

english, 1987

66

Pteridine Nucleosides—New Versatile Building Blocks in Oligonucleotide Synthesis

Charubala, Ramamurthy, Maurinsh, Juris, Rösler, Angelika, Melguizo, Manuel, Jungmann, Oliver, Gottlieb, Margarete, Lehbauer, Jörg, Hawkins, Mary, Pfleiderer, Wolfgang

Journal:

Nucleosides and Nucleotides

Year:

1997

Language:

english

File:

PDF, 419 KB

english, 1997

67

2′,5′-Phosphodiesterase Activity Depends Upon the Presence of a 3-Hydroxyl Moiety in the Penultimate Position of the Oligonucleotide Substrate

Alster, David, Brozda, Danuta, Kitade, Yukio, Wong, Alice, Charubala, Ramamurthy, Pfleiderer, Wolfgang, Torrence, Paul

Journal:

Nucleosides and Nucleotides

Year:

1987

Language:

english

File:

PDF, 109 KB

english, 1987

68

Conformationsl analysis of the trinucleoside diphosphate 3′d(A2′-5′A2′-5′A). An NMR and CD study

Doornbos, Johannes, Charubala, Ramamurthy, Pfleiderer, Wolfgang, Altona, Cornelis

Journal:

Nucleic Acids Research

Year:

1983

Language:

english

File:

PDF, 524 KB

english, 1983

69

Synthesis and Biological Activity of 3′-Modified 2′-5′ Adenylate Trimers

Herdewijn, P., Charubala, R., Pauwels, R., Clercq, E. De, Pfleiderer, W.

Journal:

Nucleosides and Nucleotides

Year:

1987

Language:

english

File:

PDF, 111 KB

english, 1987

70

The Chemical Syntheses of (2′-5′)-P-Thioadenylate Dimers, Trimers and Tetramers

Charubala, R., Pfleiderer, W.

Journal:

Nucleosides and Nucleotides

Year:

1988

Language:

english

File:

PDF, 173 KB

english, 1988

71

Synthesis and Activity of Oligonucleotides Containing a Biologically Active Nucleoside at the 2′End

Herdewijn, P., Charubala, R., Pauwels, R., Clercq, E. De, Pfleiderer, W.

Journal:

Nucleosides and Nucleotides

Year:

1987

Language:

english

File:

PDF, 97 KB

english, 1987

72

Stereochemical Problems in Oligonucleotide Synthesis

Charubala, R., Stengele, K. P., Pfleiderer, W.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

1989

Language:

english

File:

PDF, 154 KB

english, 1989

73

Synthesis and Biological Activity of a Bis-Substituted 3′-Deoxyadenosine Analog of 2–5A

Charubala, Ramamurthy, Pfleiderer, Wolfgang, Alster, David, Brozda, Danuta, Torrence, Paul F.

Journal:

Nucleosides and Nucleotides

Year:

1989

Language:

english

File:

PDF, 514 KB

english, 1989

74

Syntheses of tri, penta and nonameric nucleotides containing purine and pteridine bases

Charubala, R., Pfleiderer, W.

Journal:

Nucleic Acids Research

Year:

1978

Language:

english

File:

PDF, 140 KB

english, 1978

75

The Ultraviolet Spectra of Phenolic Aporphines in Basic Solution

Shamma, Maurice, Yao, S, Pai, B, Charubala, R

Journal:

Journal of Organic Chemistry

Year:

1971

Language:

english

File:

PDF, 189 KB

english, 1971

76

Model Studies Towards the Automated Synthesis of tRNAs

Pfleiderer, W., Pfister, M., Farkas, S., Schirmeister, H., Charubala, R., Stengele, K. P., Mohr, M., Bergmann, F., Gokhale, S.

Journal:

Nucleosides and Nucleotides

Year:

1991

Language:

english

File:

PDF, 228 KB

english, 1991

77

2′-OH Protection by the p-Nitrophenylethylsulfonyl (NPES) Group in Oligoribonucleotide Synthesis

Charubala, R., Pfleiderer, W.

Journal:

Nucleosides and Nucleotides

Year:

1987

Language:

english

File:

PDF, 166 KB

english, 1987

78

Chemical synthesis and biological characterization of phosphorothioate analogs of 2’, 5’-3’-deoxyadenylate trimer

Sobol, Robert W., Charubala, Ramamurthy, Pfleiderer, Wolfgang, Suhadolnik, Robert J.

Journal:

Nucleic Acids Research

Year:

1993

Language:

english

File:

PDF, 2.32 MB

english, 1993

79

Nucleotides XXIV; 1 Preparative Synthesis of Trimeric (2′-5′) Oligoadenylic Acid

Kyasyuk, Evgeny I., Kulak, Tamara I., Khripach, Natalya B., Mikhailopulo, Igor A., Uhlmann, Eugen, Charubala, Ramamurthy, Pfleiderer, Wolfgang

Journal:

Year:

1987

File:

PDF, 545 KB

1987

80

Nucleotides; XXIII 1 Synthesis of Protected 2′-Deoxyribonucleoside-3′,-phosphotriesters containing the p -Nitrophenylethyl Phosphate Blocking Group

Charubala, R., Uhlmann, E., Beiter, A. H., Pfleiderer, W.

Journal:

Year:

1984

File:

PDF, 389 KB

1984

81

Nucleosides. LXII. Synthesis of 6-Methyl-8-(2-deoxy-β-D-ribofuranosyl)-isoxanthopterin and Derivatives

Melguizo, M., Gottlieb, M., Charubala, R., Pfleiderer, W.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

1998

Language:

english

File:

PDF, 837 KB

english, 1998

82

Phosphorothioate Analogs OF 2-5A: Activation / Inhibition of Rnase L and Inhibition of HIV-1 Reverse Transcriftase

Suhadolnik, Robert, Lebleu, Bernard, Pfleiderer, Wolfgang, Charubala, Ramamurthy, Montefiori, David, Mitchell, William, Sobol, Robert, Li, Shi Wu, Kariko, Katalin, Reichenbach, Nancy

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

1989

Language:

english

File:

PDF, 409 KB

english, 1989

83

ChemInform Abstract: Nucleotides. Part 24. Preparative Synthesis of Trimeric (2′-5′)Oligoadenylic Acid.

KVASYUK, E. I., KULAK, T. I., KHRIPACH, N. B., MIKHAILOPULO, I. A., UHLMANN, E., CHARUBALA, R., PFLEIDERER, W.

Journal:

Year:

1987

File:

PDF, 87 KB

1987

84

Phosphorothioate and cordycepin analogues of 2',5'-oligoadenylate: inhibition of human immunodeficiency virus type 1 reverse transcriptase and infection in vitro.

Montefiori, D. C., Sobol, R. W., Li, S. W., Reichenbach, N. L., Suhadolnik, R. J., Charubala, R., Pfleiderer, W., Modliszewski, A., Robinson, W. E., Mitchell, W. M.

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 814 KB

english, 1989

85

ChemInform Abstract: Nucleotides. Part 25. Chemical Synthesis of the Hexaribonucleotide C-A-A-C-C-A.

ICHIBA, M., CHARUBALA, R., VARMA, R. S., PFLEIDERER, W.

Journal:

Year:

1987

File:

PDF, 319 KB

1987

86

ChemInform Abstract: Nucleotides. Part 30. Chemical Synthesis of Adenylyl-(2′ → 5′)-adenylyl-(2′ → 5′)-8-azidoadenosine, and Activation and Photoaffinity Labeling of RNase L by (32P)p5′A2′p5′A2′p5′N3 8A.

CHARUBALA, R., PFLEIDERER, W., SOBOL, R. W., LI, S. W., SUHADOLNIK, R. J.

Journal:

Year:

1989

File:

PDF, 103 KB

1989

87

ChemInform Abstract: Nucleotides. Part 31. Modified Oligomeric 2′-5′ A Analogues: Synthesis of 2′-5′ Oligonucleotides with 9-(3′-Azido-3′-deoxy-β-D-xylofuranosyl)adenine and 9-(3′-Amino-3′-deoxy-β-D-xylofuranosyl)adenine as Modified Nucleosides.

HERDEWIJN, P., CHARUBALA, R., PFLEIDERER, W.

Journal:

Year:

1990

File:

PDF, 200 KB

1990

88

Core (2'-5')oligoadenylate and the cordycepin analog: inhibitors of Epstein--Barr virus-induced transformation of human lymphocytes in the absence of interferon.

Doetsch, P. W., Suhadolnik, R. J., Sawada, Y., Mosca, J. D., Flick, M. B., Reichenbach, N. L., Dang, A. Q., Wu, J. M., Charubala, R., Pfleiderer, W., Henderson, E. E.

Journal:

Proceedings of the National Academy of Sciences

Year:

1981

Language:

english

File:

PDF, 1.07 MB

english, 1981

89

ChemInform Abstract: Nucleotides. Part 28. Chemical Syntheses of the 2′-5′-Cordycepin-Trimer Core (I).

CHARUBALA, R., UHLMANN, E., HIMMELSBACH, F., PFLEIDERER, W.

Journal:

Year:

1988

File:

PDF, 109 KB

1988

90

Inhibition of Morphine-Potentiated HIV-1 Replication in Peripheral Blood Mononuclear Cells With the Nuclease-Resistant 2-5A Agonist Analog, 2-5AN6B

Homan, Joseph W., Steele, Amber D., Martinand-Mari, Camille, Rogers, Thomas J., Henderson, Earl E., Charubala, Ramamurthy, Pfleiderer, Wolfgang, Reichenbach, Nancy L., Suhadolnik, Robert J.

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2002

File:

PDF, 7.66 MB

2002

91

ChemInform Abstract: Nucleotides. Part 27. Bis(2-(p-nitrophenyl)ethyl) Phosphorochloridate, a New Versatile Phosphorylating Agent in Nucleotide Chemistry.

HIMMELSBACH, F., CHARUBALA, R., PFLEIDERER, W.

Journal:

Year:

1987

File:

PDF, 256 KB

1987

92

ChemInform Abstract: Nucleotides. Part 32. Synthesis of 2′-5′ Connected Oligonucleotides. Prodrugs for Antiviral and Antitumoral Nucleosides.

HERDEWIJN, P., CHARUBALA, R., DE CLERCQ, E., PFLEIDERER, W.

Journal:

Year:

1990

File:

PDF, 164 KB

1990

93

Inhibition of Morphine-Potentiated HIV-1 Replication in Peripheral Blood Mononuclear Cells With the Nuclease-Resistant 2-5A Agonist Analog, 2-5AN6B

Homan, Joseph W., Steele, Amber D., Martinand-Mari, Camille, Rogers, Thomas J., Henderson, Earl E., Charubala, Ramamurthy, Pfleiderer, Wolfgang, Reichenbach, Nancy L., Suhadolnik, Robert J.

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2002

File:

PDF, 7.66 MB

2002

94

Studies in Protoberberine Aikaloids XVII — Neooxyberberine Acetone

R. Govindachari, Tuticorin, R. Pai, Bantwal, Rajeswari, Sundaramurthy, Natarajan, Sankaran, Chandrasekaran, Sundaram, S. Premila, Manakkal, Charubala, Ramamurthy

Journal:

Year:

1981

Language:

english

File:

PDF, 540 KB

english, 1981

95

Studies on the Syntheses of Heterocyclic Compounds. CDLXXXII. Total Photolytic Synthesis of (±)-Epicrinine

KAMETANI, TETSUJI, KOHNO, TETSUYA, CHARUBALA, RAMAMURTY, SHIBUYA, SHIROSHI, FUKUMOTO, KEIICHIRO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1972

File:

PDF, 588 KB

1972

96

Syntheses of a proerythrinadienone by phenolic oxidation and a morphinandienone system by a photo-pschorr reaction

Kametani, T., Charubala, R., Ihara, M., Koizumi, M., Takahashi, K., Fukumoto, K.

Journal:

Journal of the Chemical Society C Organic

Year:

1971

Language:

english

File:

PDF, 564 KB

english, 1971

97

Phosphorothioate and cordycepin analogues of 2',5'-oligoadenylate: inhibition of human immunodeficiency virus type 1 reverse transcriptase and infection in vitro.

Montefiori, D C, Sobol, R W, Li, S W, Reichenbach, N L, Suhadolnik, R J, Charubala, R, Pfleiderer, W, Modliszewski, a, Robinson, W E, Mitchell, W M

Journal:

Proceedings of the National Academy of Sciences of the United States of America

Year:

1989

Language:

english

File:

PDF, 814 KB

english, 1989

98

Biochemical Dysregulation of the 2-5A Synthetase/RNase L Antiviral Defense Pathway in Chronic Fatigue Syndrome

Suhadolnik, Robert J., Lombardi, Vincent, Peterson, Daniel L., Welsch, Suzanne, Cheney, Paul R., Furr, Elizabeth G., Horvath, Susan E., Charubala, Ramamurthy, Reichenbach, Nancy L., Pfleiderer, Wolfga

Journal:

Journal of Chronic Fatigue Syndrome

Year:

1999

Language:

english

File:

PDF, 334 KB

english, 1999

99

ChemInform Abstract: PROTOBERBERIN-ALKALOIDE 3. MITT. STEREOCHEMIE VON 13-METHYL-PROTOBERBERINEN

GOVINDACHARI, T. R., NAGARAJAN, K., CHARUBALA, R., PAI, B. R., SUBRAMANIAN, P. S.

Journal:

Chemischer Informationsdienst. Organische Chemie

Year:

1970

File:

PDF, 113 KB

1970

100

ChemInform Abstract: PROTOBERBERIN-ALKALOIDE 1. MITT. SYNTH. VON TETRAHYDROBERBERIN UND -EPIBERBERIN

GOVINDACHARI, T. R., NAGARAJAN, K., CHARUBALA, R., PAI, B. R.

Journal:

Chemischer Informationsdienst. Organische Chemie

Year:

1970

File:

PDF, 128 KB

1970