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101

O4-03-08 Role of nicastrin in programmed cell death

Raphaelle Pardossi-Piquard, Gang Yu, Peter St George-Hyslop, Christophe Bourdon, Cristine Alves da Costa, Frédéric Checler

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 164 KB

english, 2004

102

P1-209 APH-1 and PEN-2: a study on their proteolysis

Julie Dunys, Peter St George-Hyslop, Cristine Alves da Costa, Frédéric Checler

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 154 KB

english, 2004

103

322 Inhibitors of cathepsin D block β-secretase-like cleavage in human cells

N. Chevallier, P. Marambaud, J. Vizzavona, C.P. Baur, M. Spillantini, P. Fulcrand, J. Martinez, M. Goedert, J.P. Vincent, F. Checler

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 164 KB

english, 1996

104

694 Development of immunological tools to identify the nature of Aβs in the various lesions observed in Alzheimer's disease

H. Barelli, A. Lebeau, O. Pasquier, J. Vizzavona, P. Delaere, J.P. Vincent, J. Martinez, F. Checler

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 297 KB

english, 1996

105

α-Synuclein and the Parkinson's disease-related mutant Ala53Thr-α-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells

K Ancolio, C Alves da Costa, K Uéda, F Checler

Journal:

Neuroscience Letters

Year:

2000

Language:

english

File:

PDF, 159 KB

english, 2000

106

Cyclooxygenase-2 in the hippocampus is up-regulated in Alzheimer's disease but not in variant Alzheimer's disease with cotton wool plaques in humans

Osamu Yokota, Seishi Terada, Hideki Ishizu, Takeshi Ishihara, Hiroshi Ujike, Hanae Nakashima, Yoshihiko Nakashima, Aki Kugo, Frédéric Checler, Shigetoshi Kuroda

Journal:

Neuroscience Letters

Year:

2003

Language:

english

File:

PDF, 242 KB

english, 2003

107

Lack of effect of Presenilin 1, βAPP and their Alzheimer's disease-related mutated forms on Xenopus oocytes membrane currents

Pascale Dauch, Guy Champigny, Jean-Ehrland Ricci, Frédéric Checler

Journal:

Neuroscience Letters

Year:

1997

Language:

english

File:

PDF, 108 KB

english, 1997

108

Le mystère préséniline. La recherche vainqueur par KO ?

Frédéric Checler

Journal:

Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie

Year:

1999

Language:

french

File:

PDF, 1.26 MB

french, 1999

109

Role of the proteasome in Alzheimer’s disease

Frédéric Checler, Cristine Alves da Costa, Karine Ancolio, Nathalie Chevallier, Elvira Lopez-Perez, Philippe Marambaud

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2000

Language:

english

File:

PDF, 301 KB

english, 2000

110

2.109 A novel function of parkin as a transcriptional repressor of the oncogene p53 and its impairment by familial associated Parkinson's disease mutations

C. Alves da Costa, E. Giaime, O. Corti, A. Brice, A. West, J. Shen, M. Goldberg, F. Checler

Journal:

Parkinsonism & Related Disorders

Year:

2007

Language:

english

File:

PDF, 55 KB

english, 2007

111

2.112 DJ-1 regulation of p53 pathway and its impairment by Parkinson's disease-associated mutations

E. Giaime, C. Sunyach, H. Ariga, M. Goldberg, J. Shen, P. Heutink, F. Checler, C. Alves da Costa

Journal:

Parkinsonism & Related Disorders

Year:

2007

Language:

english

File:

PDF, 53 KB

english, 2007

112

Role of endopeptidase 3.4.24.16 in the catabolism of neurotensin, in vivo, in the vascularly perfused dog ileum

H. Barelli, J.E.T. Fox-Threlkeld, V. Dive, E.E. Daniel, J.P. Vincent, F. Checler

Journal:

British Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.21 MB

english, 1994

113

S5-02-01: P53, apoptosis

Frederic Checler

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 50 KB

english, 2006

114

S2-02-03: Regulation of Aicd Generation

Frederic Checler

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 55 KB

english, 2008

115

O4-06-01: APP and PRPC physiological metabolisms are both controlled by muscarinic receptors via ADAM17 phosphorylation

Bruno Vincent, Moustapha Alfa Cissé, Claire Sunyach, Barbara E. Slack, Abraham Fisher, Frédéric Checler

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

116

S.23.05 New functions for presenilins: do they identify novel therapeutic targets?

Journal:

European Neuropsychopharmacology

Year:

2006

Language:

english

File:

PDF, 61 KB

english, 2006

117

DEGRADATION OF NEUROTENSIN BY BRAIN SYNAPTIC MEMBRANES

Frédéric Checler, Patrick Kitabgi, Jean-Pierre Vincent

Journal:

Annals of the New York Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 135 KB

english, 1982

118

MONOIODO-Trp11-NEUROTENSIN, A NEW LIGAND TO STUDY THE INTERACTION OF NEUROTENSIN WITH ITS RECEPTOR

Jean-Pierre Vincent, Jean Mazella, Claudine Poustis, Frédéric Checler, Patrick Kitabgi, Catherin Labbé, Claude Granier, Jurphaas van Rietschoten

Journal:

Annals of the New York Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 99 KB

english, 1982

119

[TRP11]-Neurotensin and xenopsin discriminate between rat and guinea-pig neurotensin receptors

Frédéric Checler, Catherine Labbé, Claude Granier, Jurphass van Rietschoten, Patrick Kitabgi, Jean-Pierre Vincent

Journal:

Year:

1982

Language:

english

File:

PDF, 352 KB

english, 1982

120

A survey of the cerebral regionalization and ontogeny of eight exo- and endopeptidases in murines

Pascale Dauch, Yoshinori Masuo, Jean-Pierre Vincent, Frédéric Checler

Journal:

Year:

1993

Language:

english

File:

PDF, 653 KB

english, 1993

121

Differential catabolic fate of neuromedin N and neurotensin in the canine intestinal mucosa

Hélène Barelli, Y.K. Mao, B. Vincent, E.E. Daniel, J.P. Vincent, F. Checler

Journal:

Year:

1993

Language:

english

File:

PDF, 775 KB

english, 1993

122

Contribution of endopeptidase 3.4.24.15 to central neurotensin inactivation

Bruno Vincent, Jirı̀ Jiracek, Florence Noble, Mart Loog, Bernard Roques, Vincent Dive, Jean-Pierre Vincent, Frédéric Checler

Journal:

European Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 61 KB

english, 1997

123

Beta- and gamma-secretases: Could they be seen as therapeutic molecular targets

Journal:

European Neuropsychopharmacology

Year:

2001

Language:

english

File:

PDF, 312 KB

english, 2001

124

Gamma-secretase as a molecular target: Design, characterization and properties of new non peptidic inhibitors

F. Checler, A. Petit

Journal:

European Neuropsychopharmacology

Year:

2002

Language:

english

File:

PDF, 261 KB

english, 2002

125

Neurotensin Receptor Localization on Neurons Bearing the Neurotensin-Degrading Enzyme Endopeptidase 24-16

J. CHABRY, F. CHECLER, J. P. VINCENT, J. MAZELLA

Journal:

Annals of the New York Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 160 KB

english, 1992

126

Neurotensin and Neuromedin N Undergo Distinct Proteolytic Inactivation in Ventral Tegmental Area and Nucleus Accumbens

FRÉDÉRIC CHECLER, PASCALE DAUCH, YOSHINORI MASUO, JEAN-PIERRE VINCENT

Journal:

Annals of the New York Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 201 KB

english, 1992

127

ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1

Duplan, E., Giaime, E., Viotti, J., Sevalle, J., Corti, O., Brice, A., Ariga, H., Qi, L., Checler, F., Alves da Costa, C.

Journal:

Journal of Cell Science

Year:

2013

Language:

english

File:

PDF, 902 KB

english, 2013

128

BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer’s disease

Linda Chami, Frédéric Checler

Journal:

Molecular Neurodegeneration

Year:

2012

Language:

english

File:

PDF, 503 KB

english, 2012

129

Synthesis and analgesic effects of N-[3-[(hydroxyamino)carbonyl]-1-oxo-2(R)-benzylpropyl]-L-isoleucyl-L-leucine, a new potent inhibitor of multiple neurotensin/neuromedin N degrading enzymes

Doulut, Sylvie, Dubuc, Isabelle, Rodriguez, M., Vecchini, F., Fulcrand, H., Barelli, H., Checler, F., Bourdel, E., Aumelas, A.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 1.31 MB

english, 1993

130

Alzheimer's and prion diseases: PDK1 at the crossroads

Checler, Frédéric

Journal:

Nature Medicine

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013

131

Parkin acts as a transcription factor modulating presenilin-1 and presenilin-2 promoter transactivations

Duplan, Eric, Sévalle, Jean, Viotti, Julien, Goiran, Thomas, Bauer, Charlotte, Renbaum, Paul, Levy-Lahad, Ephrat, Gautier, Clément A, Corti, Olga, Leroudier, Nathalie, Checler, Frédéric, da Costa, Cri

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 87 KB

english, 2013

132

The beta-secretase-derived C-terminal fragment of APP (C99): a key determinant for intraneuronal pathology in the 3xTgAD mouse

Lauritzen, Inger, Pardossi-Piquard, Raphaelle, Druon, Charlotte, Brigham, Elizabeth, Abraham, Daniel, Ranaldi, Sébatien, Chami, Linda, Dunys, Julie, Checler, Fréderic

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 66 KB

english, 2013

133

Leaky Ryanodine receptors increases Amyloid-beta load and induces memory impairments in Tg2576 mouse model of Alzheimer disease

Oulès, Bénédicte, Del Prete, Dolores, Greco, Barbara, Zhang, Xuexin, Lauritzen, Inger, Trebak, Mohamed, Benfenati, Fabio, Checler, Frédéric, Chami, Mounia

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 84 KB

english, 2013

134

The transcription factor XBP-1 in neurodegenerative diseases

Frédéric Checler,Eric Duplan,Cristine Alves da Costa

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 74 KB

english, 2013

135

Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta -amyloid peptides

Greenfield, J. P., Tsai, J., Gouras, G. K., Hai, B., Thinakaran, G., Checler, F., Sisodia, S. S., Greengard, P., Xu, H.

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 434 KB

english, 1999

136

Données fondamentales sur les pathologies amyloïde et Tau dans la maladie d’Alzheimer : quelles perspectives thérapeutiques ?

Checler, F., Buée, L.

Journal:

Annales Pharmaceutiques Françaises

Year:

2009

Language:

french

File:

PDF, 1.01 MB

french, 2009

137

Neurotensin metabolism in various tissues of central and peripheral origins: ubiquitous involvement of a novel neurotensin degrading metalloendopeptidase

Checler, Frédéric, Barelli, Hélène, Kitabgi, Patrick, Vincent, Jean-Pierre

Journal:

Year:

1988

Language:

english

File:

PDF, 711 KB

english, 1988

138

P1-9 Etude de la production du fragment C-terminal du précurseur de la protéine beta amyloïde (AICD) à partir des substrats C99 et C83

Flammang, B., Pardossi-Piquard, R., Checler, F.

Journal:

Revue Neurologique

Year:

2009

Language:

french

File:

PDF, 106 KB

french, 2009

139

P3-381 Endocytosis-dependent function of cellular prion

Sunyach, Claire, Checler, Frédéric

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 332 KB

english, 2004

140

Study on Aβ34 biology and detection in transgenic mice brains

Caillava, Céline, Ranaldi, Sébastien, Lauritzen, Inger, Bauer, Charlotte, Fareh, Jeannette, Abraham, Jean-Daniel, Checler, Frédéric

Journal:

Neurobiology of Aging

Year:

2014

Language:

english

File:

PDF, 2.15 MB

english, 2014

141

p53 in neurodegenerative diseases and brain cancers

Checler, Frédéric, Alves da Costa, Cristine

Journal:

Pharmacology & Therapeutics

Year:

2014

Language:

english

File:

PDF, 689 KB

english, 2014

142

γ-secretase composition and cellular trafficking

Meckler, Xavier, Checler, Frederic

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 50 KB

english, 2011

143

Author index

Buggia, Virginie, Lisowski, Vincent, Hernandez, Jean-François, Rossner, Steffen, Checler, Frédéric

Journal:

Journal of Biotechnology

Year:

1990

Language:

english

File:

PDF, 144 KB

english, 1990

144

Diary of the Week

Buggia, Virginie, Lisowski, Vincent, Hernandez, Jean-François, Rossner, Steffen, Checler, Frédéric

Journal:

Year:

1982

Language:

english

File:

PDF, 143 KB

english, 1982

145

P3-237

Buggia, Virginie, Lisowski, Vincent, Hernandez, Jean-François, Rossner, Steffen, Checler, Frédéric

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

146

ROYAL COLLEGE OF SURGEONS OF ENGLAND.

Buggia, Virginie, Lisowski, Vincent, Hernandez, Jean-François, Rossner, Steffen, Checler, Frédéric

Journal:

Year:

1868

Language:

english

File:

PDF, 874 KB

english, 1868

147

Giant congenital right atrium: A very rare entity diagnosed in an adult patient

Moceri, Pamela, Berkane, Nathalie, Checler, Carine, Chiche, Olivier, Ferrari, Emile

Journal:

International Journal of Cardiology

Year:

2013

Language:

english

File:

PDF, 491 KB

english, 2013

148

Regulation of the amyloid precursor protein processing by the Nuclear Factor-kappa B

Chami, Linda, Buggia-Prevot, Virginie, Checler, Frederic

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 48 KB

english, 2011

149

P1-4 Régulation de BACE1 par NFkB

Chami, L., Buggia-Prevot, V., Checler, F.

Journal:

Revue Neurologique

Year:

2009

Language:

french

File:

PDF, 131 KB

french, 2009

150

Analogues radioactifs de la neurotensine. II. Préparation de neurotensine tritiée à partir d'un dérivé multi-insaturé de synthèse

Labbé-Jullié, Catherine, Blanot, Didier, Morgat, Jean-Louis, Kitabgi, Patrick, Checler, Frédéric, Vincent, Jean-Pierre, Granier, Claude, Van Rietschoten, Jurphaas

Journal:

Year:

1983

Language:

english

File:

PDF, 796 KB

english, 1983