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1

Successful Drug Discovery || Development of T-Cell-Engaging Bispecific Antibody Blinatumomab (Blincyto®) for Treatment of B-Cell Malignancies

Fischer, János, Klein, Christian, Childers, Wayne E.

Year:

2018

Language:

english

File:

PDF, 462 KB

english, 2018

2

Oxidation of α,β-un saturated aldehydes

Balkrishna S. Bal, Wayne E. Childers Jr., Harold W. Pinnick

Journal:

Year:

1981

Language:

english

File:

PDF, 480 KB

english, 1981

3

The Apalachee Indians and Mission San Luisby John H. Hann; Bonnie G. McEwan

Review by: Ronald Wayne Childers

Journal:

The Florida Historical Quarterly

Year:

1999

Language:

english

File:

PDF, 357 KB

english, 1999

4

Identification and Characterization of Early Mission Phase Microorganisms Residing on the Mars Science Laboratory and Assessment of Their Potential to Survive Mars-like Conditions

Smith, Stephanie A., Benardini, James N., Anderl, David, Ford, Matt, Wear, Emmaleen, Schrader, Michael, Schubert, Wayne, DeVeaux, Linda, Paszczynski, Andrzej, Childers, Susan E.

Journal:

Year:

2017

Language:

english

File:

PDF, 501 KB

english, 2017

5

The Presidio System in Spanish Florida 1565–1763

Ronald Wayne Childers

Journal:

Historical Archaeology

Year:

2004

Language:

english

File:

PDF, 304 KB

english, 2004

6

Successful Drug Discovery || Patenting Small and Large Pharmaceutical Molecules

Fischer, János, Klein, Christian, Childers, Wayne E.

Year:

2018

Language:

english

File:

PDF, 643 KB

english, 2018

7

Successful Drug Discovery || Discovery and Development of Trifluridine/Tipiracil (Lonsurf ™)

Fischer, János, Klein, Christian, Childers, Wayne E.

Year:

2018

Language:

english

File:

PDF, 1.58 MB

english, 2018

8

Democratization of ecosystem services—a radical approach for assessing nature’s benefits in the face of urbanization

McHale, Melissa R., Beck, Scott M., Pickett, Steward T. A., Childers, Daniel L., Cadenasso, Mary L., Rivers, Louie, Swemmer, Louise, Ebersohn, Liesel, Twine, Wayne, Bunn, David N

Journal:

Ecosystem Health and Sustainability

Year:

2018

Language:

english

File:

PDF, 2.28 MB

english, 2018

9

Successful Drug Discovery ||

Fischer, János, Childers, Wayne E.

Year:

2016

Language:

english

File:

PDF, 15.82 MB

english, 2016

10

Successful Drug Discovery || Ocrelizumab: A New Generation of anti‐ CD20 mAb for Treatment of Multiple Sclerosis

Fischer, János, Klein, Christian, Childers, Wayne E.

Year:

2019

Language:

english

File:

PDF, 621 KB

english, 2019

11

Successful Drug Discovery ||

Fischer, János, Klein, Christian, Childers, Wayne E.

Year:

2019

File:

PDF, 6.44 MB

2019

12

The Resurrection of Phenotypic Drug Discovery

Childers, Wayne E., Elokely, Khaled M, Abou-Gharbia, Magid

Journal:

ACS Medicinal Chemistry Letters

Year:

2020

File:

PDF, 1.97 MB

2020

13

Disruption of Kv1.1 N-type inactivation by novel small molecule inhibitors (disinactivators)

Qiang Lu, Joseph Peevey, Flora Jow, Michael M. Monaghan, Grace Mendoza, Howard Zhang, Jerome Wu, Callain Y. Kim, James Bicksler, Lynn Greenblatt, Stephen S. Lin, Wayne Childers, Mark R. Bowlby

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 898 KB

english, 2008

14

3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3

Lisa M. Havran, Dan C. Chong, Wayne E. Childers, Paul J. Dollings, Arlene Dietrich, Boyd L. Harrison, Vasilios Marathias, Gregory Tawa, Ann Aulabaugh, Rebecca Cowling, Bhupesh Kapoor, Weixin Xu, Lidia

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 739 KB

english, 2009

15

Synthesis and structure–activity relationship of novel lactam-fused chroman derivatives having dual affinity at the 5-HT1A receptor and the serotonin transporter

Zhongqi Shen, P. Siva Ramamoorthy, Nicole T. Hatzenbuhler, Deborah A. Evrard, Wayne Childers, Boyd L. Harrison, Michael Chlenov, Geoffrey Hornby, Deborah L. Smith, Kelly M. Sullivan, Lee E. Schechter,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 341 KB

english, 2010

16

A convenient, reproducible two-step synthesis of 6,6-dimethylbicyclo[3.1.1]heptane-2,4-dione

Wayne E. Childers Jr., Jerome C. Wu, Vasilios M. Marathias

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 80 KB

english, 2006

17

Advances in the development of novel analgesics

Childers, Wayne E, Gilbert, Adam M, Kennedy, Jeffrey D, Whiteside, Garth T

Journal:

Expert Opinion on Therapeutic Patents

Year:

2008

Language:

english

File:

PDF, 921 KB

english, 2008

18

Stereoselective inhibition of human placental aromatase

Wayne E. Childers, Mei-Jue Shih, Paul S. Furth, Cecil H. Robinson

Journal:

Year:

1987

Language:

english

File:

PDF, 604 KB

english, 1987

19

Reduced provirus burden and enhanced humoral immune function in AZT-treated SCID-feline mice inoculated with feline immunodeficiency virus

Calvin M. Johnson, Dean W. Selleseth, M. Nixon Ellis, Tedd A. Childers, Mary B. Tompkins, Wayne A.F. Tompkins

Journal:

Veterinary Immunology and Immunopathology

Year:

1995

Language:

english

File:

PDF, 953 KB

english, 1995

20

Synthesis and SAR of Adatanserin: Novel Adamantyl Aryl- and Heteroarylpiperazines with Dual Serotonin 5-HT 1A and 5-HT 2 Activity as Potential Anxiolytic and Antidepressant Agents

Abou-Gharbia, Magid A., Childers, Wayne E., Fletcher, Horace, McGaughey, Georgia, Patel, Usha, Webb, Michael B., Yardley, John, Andree, Terrance, Boast, Carl, Kucharik, Robert J., Marquis, Karen, Morr

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 378 KB

english, 1999

21

The Synthesis and Biological Evaluation of Quinolyl-piperazinyl Piperidines as Potent Serotonin 5-HT 1A Antagonists

Childers, Wayne E., Havran, Lisa M., Asselin, Magda, Bicksler, James J., Chong, Dan C., Grosu, George T., Shen, Zhongqi, Abou-Gharbia, Magid, A., Bach, Alvin C., Harrison, Boyd L., Kagan, Natasha, Kle

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.59 MB

english, 2010

22

Discovery of Innovative Therapeutics: Today’s Realities and Tomorrow’s Vision. 1. Criticisms Faced by the Pharmaceutical Industry

Abou-Gharbia, Magid, Childers, Wayne E.

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.93 MB

english, 2013

23

Inhibition of human placental aromatase by novel homologated 19-oxiranyl and 19-thiiranyl steroids

Childers, Wayne E., Silverton, James V., Kellis, James T., Vickery, Larry E., Robinson, Cecil H.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 793 KB

english, 1991

24

N -Methyl- d -Aspartate Antagonists and Neuropathic Pain: The Search for Relief

Childers, Wayne E., Baudy, Reinhardt B.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 155 KB

english, 2007

25

Discovery of Innovative Therapeutics: Today’s Realities and Tomorrow’s Vision. 2. Pharma’s Challenges and Their Commitment to Innovation

Abou-Gharbia, Magid, Childers, Wayne E.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 3.00 MB

english, 2014

26

Essential roles of Leu/Ile/Phe-rich domain of JC virus agnoprotein in dimer/oligomer formation, protein stability and splicing of viral transcripts

Saribas, A. Sami, Abou-Gharbia, Magid, Childers, Wayne, Sariyer, Ilker K., White, Martyn K., Safak, Mahmut

Journal:

Year:

2013

Language:

english

File:

PDF, 2.37 MB

english, 2013

27

Synthesis and Biological Evaluation of Benzodioxanylpiperazine Derivatives as Potent Serotonin 5-HT 1A Antagonists: The Discovery of Lecozotan

Childers,, Wayne E., Abou-Gharbia, Magid A., Kelly, Michael G., Andree, Terrance H., Harrison, Boyd L., Ho, Douglas M., Hornby, Geoffrey, Huryn, Donna M., Potestio, Lisa, Rosenzweig-Lipson, Sharon J.,

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 123 KB

english, 2005

28

A novel approach to the synthesis of the cannabinoids

Childers, Wayne E., Pinnick, Harold W.

Journal:

Journal of Organic Chemistry

Year:

1984

Language:

english

File:

PDF, 264 KB

english, 1984

29

Synthesis of 10.beta.-oxiranyl and 10.beta.-thiiranyl steroids

Childers, Wayne E., Furth, Paul S., Shih, Mei Jue, Robinson, Cecil H.

Journal:

Journal of Organic Chemistry

Year:

1988

Language:

english

File:

PDF, 724 KB

english, 1988

30

Novel 10?-thiiranyl steroids as aromatase inhibitors

Childers, Wayne E., Robinson, Cecil H.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1987

Language:

english

File:

PDF, 227 KB

english, 1987

31

Epilepsy drug review: patent activity from 1999 to 2002

Bowlby, Mark R, Childers Jr, Wayne E

Journal:

Expert Opinion on Therapeutic Patents

Year:

2003

Language:

english

File:

PDF, 308 KB

english, 2003

32

Progressive Expansion of an L-Selectin-Negative CD8 Cell with Anti-Feline Immunodeficiency Virus (FIV) Suppressor Function in the Circulation of FIV-Infected Cats

Douglas H. Gebhard, Janet L. Dow, Tedd A. Childers, Jose I. Alvelo, Mary B. Tompkins and Wayne A. F. Tompkins

Journal:

The Journal of Infectious Diseases

Year:

1999

Language:

english

File:

PDF, 1.92 MB

english, 1999

33

Mucosally Transmitted Feline Immunodeficiency Virus Induces a CD8 + Antiviral Response that Correlates with Reduction of Cell‐Associated Virus

Bucci, Joseph G., English, Robert V., Jordan, Holly L., Childers, Tedd A., Tompkins, Mary B., Tompkins, Wayne A. F.

Journal:

The Journal of Infectious Diseases

Year:

1998

Language:

english

File:

PDF, 216 KB

english, 1998

34

Progressive Expansion of an L‐Selectin–Negative CD8 Cell with Anti–Feline Immunodeficiency Virus (FIV) Suppressor Function in the Circulation of FIV‐Infected Cats

Gebhard, Douglas H., Dow, Janet L., Childers, Tedd A., Alvelo, Jose I., Tompkins, Mary B., Tompkins, Wayne A. F.

Journal:

The Journal of Infectious Diseases

Year:

1999

Language:

english

File:

PDF, 235 KB

english, 1999

35

The CD8 + Cell Phenotype Mediating Antiviral Activity in Feline Immunodeficiency Virus‐Infected Cats Is Characterized by Reduced Surface Expression of the CD8 β Chain

Bucci, Joseph G., Gebhard, Douglas H., Childers, Tedd A., English, Robert V., Tompkins, Mary B., Tompkins, Wayne A. F.

Journal:

The Journal of Infectious Diseases

Year:

1998

Language:

english

File:

PDF, 206 KB

english, 1998

36

Life in Miami and the Keys: Two Reports and a Map from the MonacoAlaña Mission, 1743

R. Wayne Childers

Journal:

The Florida Historical Quarterly

Year:

2003

Language:

english

File:

PDF, 2.20 MB

english, 2003

37

Presidios of the North American Spanish Borderlands || The Presidio System in Spanish Florida 1565-1763

Ronald Wayne Childers

Journal:

Historical Archaeology

Year:

2004

Language:

english

File:

PDF, 1.07 MB

english, 2004

38

Ribosome-templated azide−alkyne cycloadditions: synthesis of potent macrolide antibiotics by in situ click chemistry

Glassford, Ian, Teijaro, Christiana N., Daher, Samer S., Weil, Amy, Small, Meagan C., Redhu, Shiv K., Colussi, Dennis J., Jacobson, Marlene A., Childers, Wayne E., Buttaro, Bettina, Nicholson, Allen W

Journal:

Journal of the American Chemical Society

Year:

2016

Language:

english

File:

PDF, 4.22 MB

english, 2016

39

[Annual Reports in Medicinal Chemistry] Annual Reports in Medicinal Chemistry Volume 40 Volume 40 || Recent Advances in Selective Serotonergic Agents

Childers,, Wayne E.

Year:

2005

Language:

english

File:

PDF, 191 KB

english, 2005

40

Historic Notes and Documents: A Late Seventeenth-Century Journey to Tampa Bay

Ronald Wayne Childers

Journal:

The Florida Historical Quarterly

Year:

2002

Language:

english

File:

PDF, 1.72 MB

english, 2002

41

Targeting neurodegenerative diseases: Drug discovery in a challenging arena

Abou-Gharbia, Magid, Childers, Wayne

Journal:

Pure & Applied Chemistry

Year:

2012

Language:

english

File:

PDF, 1.32 MB

english, 2012

42

Emerging From the Unknown: Structural and Functional Features of Agnoprotein of Polyomaviruses

Saribas, A. Sami, Coric, Pascale, Hamazaspyan, Anahit, Davis, William, Axman, Rachael, White, Martyn K., Abou-Gharbia, Magid, Childers, Wayne, Condra, Jon H., Bouaziz, Serge, Safak, Mahmut

Journal:

Journal of Cellular Physiology

Year:

2016

Language:

english

File:

PDF, 2.66 MB

english, 2016

43

Mucosally Transmitted Feline Immunodeficiency Virus Induces a CD8⁺ Antiviral Response That Correlates with Reduction of Cell-Associated Virus

Joseph G. Bucci, Robert V. English, Holly L. Jordan, Tedd A. Childers, Mary B. Tompkins and Wayne A. F. Tompkins

Journal:

The Journal of Infectious Diseases

Year:

1998

File:

PDF, 1.60 MB

1998

44

Mucosally Transmitted Feline Immunodeficiency Virus Induces a CD8⁺ Antiviral Response That Correlates with Reduction of Cell-Associated Virus

Joseph G. Bucci, Robert V. English, Holly L. Jordan, Tedd A. Childers, Mary B. Tompkins and Wayne A. F. Tompkins

Journal:

The Journal of Infectious Diseases

Year:

1998

Language:

english

File:

PDF, 1.60 MB

english, 1998

45

The CD8⁺ Cell Phenotype Mediating Antiviral Activity in Feline Immunodeficiency Virus-Infected Cats Is Characterized by Reduced Surface Expression of the CD8 β Chain

Joseph G. Bucci, Douglas H. Gebhard, Tedd A. Childers, Robert V. English, Mary B. Tompkins and Wayne A. F. Tompkins

Journal:

The Journal of Infectious Diseases

Year:

1998

Language:

english

File:

PDF, 1.85 MB

english, 1998

46

Design, synthesis, and evaluation of (2S, 4R)-Ketoconazole sulfonamide analogs as potential treatments for metabolic syndrome

Blass, Benjamin E, Iyer, Pravin, Abou-Gharbia, Magid, Childers, Wayne W, Gordon, John C, Ramanjulu, Mercy, Morton, George, Arumugam, Premkumar, Boruwa, Joshodeep, Ellingboe, John, Mitra, Sayan, Nimmar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 689 KB

english, 2016

47

Successful Drug Discovery || Romidepsin and the Zinc-Binding Thiol Family of Natural Product HDAC Inhibitors

Fischer, János, Childers, Wayne E.

Year:

2016

Language:

english

File:

PDF, 669 KB

english, 2016

48

Successful Drug Discovery || Sofosbuvir: The Discovery of a Curative Therapy for the Treatment of Hepatitis C Virus

Fischer, János, Childers, Wayne E.

Year:

2016

Language:

english

File:

PDF, 1.10 MB

english, 2016

49

Successful Drug Discovery || Discovery of Delamanid for the Treatment of Multidrug-Resistant Pulmonary Tuberculosis

Fischer, János, Childers, Wayne E.

Year:

2016

Language:

english

File:

PDF, 1.57 MB

english, 2016

50

Successful Drug Discovery || Discovery and Development of Nintedanib: A Novel Antiangiogenic and Antifibrotic Agent

Fischer, János, Childers, Wayne E.

Year:

2016

Language:

english

File:

PDF, 825 KB

english, 2016

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