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51

In situ radiation-inactivation size of fibroblast membrane-bound acid β-glucosidase in Gaucher type 1, type 2 and type 3 disease

Francis Y.M. Choy, Mary Woo, Michel Potier

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1986

Language:

english

File:

PDF, 456 KB

english, 1986

52

Targeting hedgehog-GLI-2 pathway in osteosarcoma

Wen Yang, Xianzhe Liu, Edwin Choy, Henry Mankin, Francis J. Hornicek, Zhenfeng Duan

Journal:

Journal of Orthopaedic Research

Year:

2012

Language:

english

File:

PDF, 1.34 MB

english, 2012

53

A Novel Complex Allele and Two New Point Mutations in Type 2 (Acute Neuronopathic) Gaucher Disease

Graham Sinclair, Francis Y.M Choy, Lisa Humphries

Journal:

Blood Cells, Molecules, and Diseases

Year:

1998

Language:

english

File:

PDF, 157 KB

english, 1998

54

Heterologous Expression and Characterization of a Rare Gaucher Disease Mutation (c.481C > T) from a Canadian Aboriginal Population Using Archival Tissue Samples

Graham Sinclair, Francis Y.M. Choy, Patrick Ferreira

Journal:

Molecular Genetics and Metabolism

Year:

2001

Language:

english

File:

PDF, 178 KB

english, 2001

55

Purification and reconstitution studies of the nucleoside transporter from pig erythrocytes

Francis Y.P. Kwong, Chung-Ming Tse, Simon M. Jarvis, Matthew Y.M. Choy, James D. Young

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1987

Language:

english

File:

PDF, 993 KB

english, 1987

56

Glucocerebrosidase recombinant allele: Molecular evolution of the glucocerebrosidase gene and pseudogene in primates

Julie R. Wafaei, Francis Y.M. Choy

Journal:

Blood Cells, Molecules, and Diseases

Year:

2005

Language:

english

File:

PDF, 1.00 MB

english, 2005

57

Gaucher disease among Chinese patients: Review on genotype/phenotype correlation from 29 patients and identification of novel and rare alleles

Francis Y.M. Choy, Weimin Zhang, Hui-Ping Shi, Agnes Zay, Tessa Campbell, Nelson Tang, Patrick Ferreira

Journal:

Blood Cells, Molecules, and Diseases

Year:

2007

Language:

english

File:

PDF, 353 KB

english, 2007

58

Lentiviral shRNA screen of human kinases identifies PLK1 as a potential therapeutic target for osteosarcoma

Zhenfeng Duan, Diana Ji, Edward J. Weinstein, Xianzhe Liu, Michiro Susa, Edwin Choy, Cao Yang, Henry Mankin, Francis J. Hornicek

Journal:

Year:

2010

Language:

english

File:

PDF, 1.93 MB

english, 2010

59

Generation of a conditional knockout of murine glucocerebrosidase: Utility for the study of Gaucher disease

Graham B. Sinclair, Gareth Jevon, Karen E. Colobong, Derrick R. Randall, Francis Y.M. Choy, Lorne A. Clarke

Journal:

Molecular Genetics and Metabolism

Year:

2007

Language:

english

File:

PDF, 2.08 MB

english, 2007

60

79 Type II perinatal lethal Gaucher disease: Identification of a novel mutation, P332L, in a case study from Vancouver Island, British Columbia, Canada

Francis Choy, Agnes Zay, Patrick MacLeod, Cherrie R. Tan-Dy

Journal:

Molecular Genetics and Metabolism

Year:

2007

Language:

english

File:

PDF, 55 KB

english, 2007

61

Acyl-GPC and alkenyl/alkyl-GPC:acyl-CoA acyltransferases

Patrick C Choy, Monika Skrzypczak, Douglas Lee, Francis T Jay

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1997

Language:

english

File:

PDF, 111 KB

english, 1997

62

Synonymous codon usage bias and the expression of human glucocerebrosidase in the methylotrophic yeast, Pichia pastoris

Graham Sinclair, Francis Y.M. Choy

Journal:

Protein Expression and Purification

Year:

2002

Language:

english

File:

PDF, 247 KB

english, 2002

63

Purification and characterization of activated human erythrocyte prolidase

Richter, Andrea M., Lancaster, Gerald L., Choy, Francis Y. M., Hechtman, Peter

Journal:

Biochemistry and Cell Biology

Year:

1989

Language:

english

File:

PDF, 1.17 MB

english, 1989

64

Stereoselective aldol condensation. Use of chiral boron enolates

Masamune, Satoru, Choy, William, Kerdesky Francis A. J.,, Imperiali, Barbara

Journal:

Journal of the American Chemical Society

Year:

1981

Language:

english

File:

PDF, 360 KB

english, 1981

65

Coordination chemistry of siloles: synthesis, reactions, and stereochemistry of silicon-substituted (.eta.4-2,5-diphenylsilacyclopentadiene)transition-metal complexes. Crystal structure of dicarbonyl[phenyl((.eta.4-exo-1-methyl-2,5-diphenylsilacyclopentadien-1-yl)oxy)carbene]iron

Carre, Francis., Corriu, Robert J. P., Guerin, Christian., Henner, Bernard J. L., Wong Chi Man, Wong Wee Choy.

Journal:

Organometallics

Year:

1989

Language:

english

File:

PDF, 1.50 MB

english, 1989

66

Human α-N-acetylglucosaminidase: cDNA cryptic site removal and native secretion signal addition significantly enhance enzyme expression and secretion

Jantzen, Roni Rebecca, Truelson, Sarah N., Choy, Francis Y.M.

Journal:

Process Biochemistry

Year:

2013

Language:

english

File:

PDF, 664 KB

english, 2013

67

Two novel mutations in glucocerebrosidase, C23W and IVS7−1 G>A, identified in Type 1 Gaucher patients heterozygous for N370S

Jack, Alexandria, Amato, Dominick, Morris, Geoffrey, Choy, Francis Y.M.

Journal:

Year:

2014

Language:

english

File:

PDF, 385 KB

english, 2014

68

Cyclin-dependent kinase 11 (CDK11) is crucial in the growth of liposarcoma cells

Jia, Bin, Choy, Edwin, Cote, Gregory, Harmon, David, Ye, Shunan, Kan, Quancheng, Mankin, Henry, Hornicek, Francis, Duan, Zhenfeng

Journal:

Year:

2014

Language:

english

File:

PDF, 1.90 MB

english, 2014

69

Neoadjuvant chemoradiotherapy for patients with high-risk extremity and truncal sarcomas: A 10-year single institution retrospective study

Hong, Nicole J. Look, Hornicek, Francis J., Harmon, David C., Choy, Edwin, Chen, Yen-Lin, Yoon, Sam S., Nielsen, G. Petur, Szymonifka, Jackie, Yeap, Beow Y., DeLaney, Thomas F., Mullen, John T.

Journal:

European Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 317 KB

english, 2013

70

Secretion of human glucocerebrosidase from stable transformed insect cells using native signal sequences

Sinclair, Graham, Pfeifer, Tom A, Grigliatti, Thomas A, Choy, Francis Y.M

Journal:

Biochemistry and Cell Biology

Year:

2006

File:

PDF, 234 KB

2006

71

Synthesis and Evaluation of (2-(4-Methoxyphenyl)-4-quinolinyl)(2-piperidinyl)methanol (NSC23925) Isomers To Reverse Multidrug Resistance in Cancer

Duan, Zhenfeng, Li, Xin, Huang, Haoxi, Yuan, Wei, Zheng, Shao-Liang, Liu, Xianzhe, Zhang, Zhan, Choy, Edwin, Harmon, David, Mankin, Henry, Hornicek, Francis

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 4.13 MB

english, 2012

72

Interaction of Daunomycin with Acetylated Chromatin

Sprigg, Lyndsay, Li, Andra, Choy, Francis Y. M., Ausió, Juan

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 4.44 MB

english, 2010

73

Purification and the effect of peptide N -glycosidase F on lysosomal membrane-bound glucocerebrosidase from human cultured fibroblasts

Choy, Francis Y. M., Woo, Mary

Journal:

Biochemistry and Cell Biology

Year:

1991

Language:

english

File:

PDF, 933 KB

english, 1991

74

Glycine cleavage enzyme complex: Rabbit H-protein cDNA sequence analysis and comparison to human, cow, and chicken

Choy, Francis, Sharp, Lisa, Applegarth, Derek A

Journal:

Biochemistry and Cell Biology

Year:

2000

File:

PDF, 3.58 MB

2000

75

Glycine cleavage enzyme complex: Molecular cloning and expression of the H-protein cDNA from cultured human skin fibroblasts

Zay, Agnes, Choy, Francis Y.M., Patrick, Chelsea, Sinclair, Graham

Journal:

Biochemistry and Cell Biology

Year:

2011

File:

PDF, 761 KB

2011

76

Investigation of Pharmacological Chaperones and Gluthathione in the Enhancement of NAcetylgalactosamine- 6-Sulfate Sulfatase (GALNS) in the Treatment of Mucopolysaccharidosis IVA

Walter, Patrick, Otto, Shane, Sharf, Kyle, Riddett, Elizabeth, Huey Tan, Hsein, Fournier, Roxanne, Zhang, Fuming, Choy, Francis, Linhardt, Robert, Lum, Julian, Harmatz, Paul

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 90 KB

english, 2014

77

Prognostic significance of miRNA-1 (miR-1) expression in patients with chordoma

Duan, Zhenfeng, Shen, Jacson, Yang, Xiaoqian, Yang, Pei, Osaka, Eiji, Choy, Edwin, Cote, Gregory, Harmon, David, Zhang, Yu, Nielsen, G. Petur, Spentzos, Dimitrios, Mankin, Henry, Hornicek, Francis

Journal:

Journal of Orthopaedic Research

Year:

2014

Language:

english

File:

PDF, 599 KB

english, 2014

78

Anti-HLA Alloantibody Is Found in Children But Does Not Correlate with a Lack of HIV Type 1 Transmission from Infected Mothers

LUSCHER, MARK A., CHOY, GREGORY, EMBREE, JOANNE E., NAGELKERKE, NICOLAAS J.D., BWAYO, JOB J., NJENGA, SIMON, PLUMMER, FRANCIS A., BARBER, BRIAN H., MacDONALD, KELLY S.

Journal:

AIDS Research and Human Retroviruses

Year:

1998

Language:

english

File:

PDF, 1.56 MB

english, 1998

79

Naturally Occurring IgG Anti-HLA Alloantibody Does Not Correlate with HIV Type 1 Resistance in Nairobi Prostitutes

LUSCHER, MARK A., CHOY, GREGORY, NJAGI, EPHANTAS, BWAYO, JOB J., ANZALA, AGGREY O., NDINYA-ACHOLA, JACKONIAH O., BALL, T. BLAKE, WADE, JUDY A., PLUMMER, FRANCIS A., BARBER, BRIAN H., MacDONALD, KELLY

Journal:

AIDS Research and Human Retroviruses

Year:

1998

Language:

english

File:

PDF, 1.18 MB

english, 1998

80

Effects of amino acids and ethanolamine on choline uptake and phosphatidylcholine biosynthesis in baby hamster kidney-21 cells

Zha, Xiliang, Jay, Francis T., Choy, Patrick C.

Journal:

Biochemistry and Cell Biology

Year:

1992

Language:

english

File:

PDF, 941 KB

english, 1992

81

Cluster of Differentiation 44 Targeted Hyaluronic Acid Based Nanoparticles forMDR1siRNA Delivery to Overcome Drug Resistance in Ovarian Cancer

Yang, Xiaoqian, Iyer, Arun K., Singh, Amit, Milane, Lara, Choy, Edwin, Hornicek, Francis J., Amiji, Mansoor M., Duan, Zhenfeng

Journal:

Pharmaceutical Research

Year:

2015

Language:

english

File:

PDF, 4.80 MB

english, 2015

82

Targeting programmed cell death ligand 1 in osteosarcoma: an auto-commentary on therapeutic potential

Shen, Jacson K, Cote, Gregory M, Choy, Edwin, Hornicek, Francis J, Duan, Zhenfeng

Journal:

Year:

2014

Language:

english

File:

PDF, 250 KB

english, 2014

83

Prognostic significance of treatment-induced pathologic necrosis in extremity and truncal soft tissue sarcoma after neoadjuvant chemoradiotherapy

Mullen, John T., Hornicek, Francis J., Harmon, David C., Raskin, Kevin A., Chen, Yen-Lin, Szymonifka, Jackie, Yeap, Beow Y., Choy, Edwin, DeLaney, Thomas F., Nielsen, G. Petur

Journal:

Year:

2014

Language:

english

File:

PDF, 195 KB

english, 2014

84

MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer

Yang, Xiaoqian, lyer, Arun K., Singh, Amit, Choy, Edwin, Hornicek, Francis J., Amiji, Mansoor M., Duan, Zhenfeng

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 4.58 MB

english, 2015

85

A-770041 reverses paclitaxel and doxorubicin resistance in osteosarcoma cells

Duan, Zhenfeng, Zhang, Jianming, Ye, Shunan, Shen, Jacson, Choy, Edwin, Cote, Gregory, Harmon, David, Mankin, Henry, Hua, Yingqi, Zhang, Yu, Gray, Nathanael S, Hornicek, Francis J

Journal:

Year:

2014

Language:

english

File:

PDF, 1.35 MB

english, 2014

86

NSC23925 prevents the emergence of multidrug resistance in ovarian cancer in vitro and in vivo

Yang, Xiaoqian, Feng, Yong, Gao, Yan, Shen, Jacson, Choy, Edwin, Cote, Gregory, Harmon, David, Zhang, Zhan, Mankin, Henry, Hornicek, Francis J., Duan, Zhenfeng

Journal:

Gynecologic Oncology

Year:

2015

Language:

english

File:

PDF, 1.57 MB

english, 2015

87

A new missense mutation in glucocerebrosidase exon 9 of a non Jewish Caucasian type 1 Gaucher disease patient

Choy, Francis Y.M., Wei, Chao, Applegarth, Derek A., Yong, Siu-Li

Journal:

Human Molecular Genetics

Year:

1994

Language:

english

File:

PDF, 2.24 MB

english, 1994

88

Gaucher Disease and Cancer: Concept and Controversy

Choy, Francis Y. M., Campbell, Tessa N.

Journal:

International Journal of Cell Biology

Year:

2011

Language:

english

File:

PDF, 95 KB

english, 2011

89

Expression of Active α-N-Acetylglucosaminidase/TAT Chimerae in Cultured Spodoptera frugiperda Cells

Bandsmer, Judith, Campbell, Tessa, Cheyne, Ian, Choy, Francis

Journal:

Protein & Peptide Letters

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

90

Gaucher Disease with Prenatal Onset and Perinatal Death Due to Compound Heterozygosity for the Missense R131C and Null RecNciI GBA Mutations

Goebl, April, Ferrier, Raechel A., Ferreira, Patrick, Pinto-Rojas, Alfredo, Matshes, Evan, Choy, Francis Y. M.

Journal:

Pediatric and Developmental Pathology

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

91

CD44 is a direct target of miR-199a-3p and contributes to aggressive progression in osteosarcoma

Gao, Yan, Feng, Yong, Shen, Jacson K., Lin, Min, Choy, Edwin, Cote, Gregory M., Harmon, David C., Mankin, Henry J., Hornicek, Francis J., Duan, Zhenfeng

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.17 MB

english, 2015

92

Sanfilippo syndrome type B: Reprogramming cultured skin fibroblasts to induced pluripotent stem cells using non-integrating Sendai virus vector

Turner, Kelly A., Choy, Francis Y.

Journal:

Molecular Genetics and Metabolism

Year:

2015

Language:

english

File:

PDF, 54 KB

english, 2015

93

Survey, purification, and properties of sugar phosphate phosphohydrolase among microorganisms

Choy, Francis Y. M., Lee, Ya-Pin

Journal:

Biochemistry and Cell Biology

Year:

1983

Language:

english

File:

PDF, 1.10 MB

english, 1983

94

Gaucher's Disease. I. Solubilization and Electrophoresis of β-Glucosidase from Leukocytes and Cultured Fibroblasts

Choy, Francis Y M, Davidson, Ronald G

Journal:

Pediatric Research

Year:

1978

Language:

english

File:

PDF, 608 KB

english, 1978

95

p53 overexpression increases chemosensitivity in multidrug-resistant osteosarcoma cell lines

Ye, Shunan, Shen, Jacson, Choy, Edwin, Yang, Cao, Mankin, Henry, Hornicek, Francis, Duan, Zhenfeng

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.37 MB

english, 2016

96

Pinhole-Free and Surface-Nanostructured NiOx Film by Room-Temperature Solution Process for High-Performance Flexible Perovskite Solar Cells with Good Stability and Reproducibility

ZHANG, Hong, Cheng, Jiaqi, Lin, Francis, He, hexiang, Mao, Jian, Wong, Kam Sing, Jen, Alex K. -Y., Choy, Wallace C.H.

Journal:

Year:

2015

Language:

english

File:

PDF, 3.21 MB

english, 2015

97

Development and potential applications of CRISPR-Cas9 genome editing technology in sarcoma

Liu, Tang, Shen, Jacson K., Li, Zhihong, Choy, Edwin, Hornicek, Francis J., Duan, Zhenfeng

Journal:

Year:

2016

Language:

english

File:

PDF, 1.39 MB

english, 2016

98

Targeting protein kinases to reverse multidrug resistance in sarcoma

Chen, Hua, Shen, Jacson, Choy, Edwin, Hornicek, Francis J., Duan, Zhenfeng

Journal:

Cancer Treatment Reviews

Year:

2016

Language:

english

File:

PDF, 1.41 MB

english, 2016

99

Identification of novel splice site mutation IVS9+1(G>A) and novel complex allele G355R/R359X in Type 1 Gaucher patients heterozygous for mutation N370S

Hoitsema, Kourtnee, Amato, Dominick, Khan, Aneal, Sirrs, Sandra, Choy, Francis Y.M.

Journal:

Year:

2016

Language:

english

File:

PDF, 786 KB

english, 2016

100

Inhibition of polo-like kinase 1 leads to the suppression of osteosarcoma cell growth in vitro and in vivo

Liu, Xianzhe, Choy, Edwin, Harmon, David, Yang, Shuhua, Yang, Cao, Mankin, Henry, Hornicek, Francis J., Duan, Zhenfeng

Journal:

Anti-Cancer Drugs

Year:

2011

Language:

english

File:

PDF, 469 KB

english, 2011